IL103493A - Use of 2 - amino - 6 -) trifluoromethoxy (benzothiazole for the preparation of the drug for the treatment of neuro-motor diseases - Google Patents

Use of 2 - amino - 6 -) trifluoromethoxy (benzothiazole for the preparation of the drug for the treatment of neuro-motor diseases

Info

Publication number
IL103493A
IL103493A IL10349392A IL10349392A IL103493A IL 103493 A IL103493 A IL 103493A IL 10349392 A IL10349392 A IL 10349392A IL 10349392 A IL10349392 A IL 10349392A IL 103493 A IL103493 A IL 103493A
Authority
IL
Israel
Prior art keywords
amino
benzothiazole
treatment
trifluoromethoxy
preparing
Prior art date
Application number
IL10349392A
Other languages
English (en)
Hebrew (he)
Other versions
IL103493A0 (en
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9427427&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL103493(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of IL103493A0 publication Critical patent/IL103493A0/xx
Publication of IL103493A publication Critical patent/IL103493A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Surgical Instruments (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Medicinal Preparation (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
IL10349392A 1992-03-06 1992-10-21 Use of 2 - amino - 6 -) trifluoromethoxy (benzothiazole for the preparation of the drug for the treatment of neuro-motor diseases IL103493A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9202696A FR2688138B1 (fr) 1992-03-06 1992-03-06 Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique.

Publications (2)

Publication Number Publication Date
IL103493A0 IL103493A0 (en) 1993-03-15
IL103493A true IL103493A (en) 1996-07-23

Family

ID=9427427

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10349392A IL103493A (en) 1992-03-06 1992-10-21 Use of 2 - amino - 6 -) trifluoromethoxy (benzothiazole for the preparation of the drug for the treatment of neuro-motor diseases

Country Status (22)

Country Link
US (1) US5527814A (de)
EP (2) EP0558861A1 (de)
JP (1) JP2713384B2 (de)
KR (1) KR100190296B1 (de)
AT (1) ATE149833T1 (de)
AU (1) AU666150B2 (de)
CA (1) CA2117466C (de)
CZ (1) CZ281293B6 (de)
DE (1) DE69218255T2 (de)
DK (1) DK0627919T3 (de)
ES (1) ES2098558T3 (de)
FR (1) FR2688138B1 (de)
GR (1) GR3022797T3 (de)
HU (1) HU217130B (de)
IL (1) IL103493A (de)
MX (1) MX9206109A (de)
NO (1) NO306534B1 (de)
RU (1) RU2110260C1 (de)
SK (1) SK279046B6 (de)
UA (1) UA41879C2 (de)
WO (1) WO1993017683A1 (de)
ZA (1) ZA928213B (de)

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FR2699077B1 (fr) * 1992-12-16 1995-01-13 Rhone Poulenc Rorer Sa Application d'anticonvulsivants dans le traitement de lésions neurologiques liées à des traumatismes.
FR2702148B1 (fr) * 1993-03-05 1995-04-07 Rhone Poulenc Rorer Sa Application d'anticonvulsivants dans le traitement du neuro-sida.
FR2714828B1 (fr) * 1994-01-12 1996-02-02 Rhone Poulenc Rorer Sa Application du riluzole dans le traitement des maladies mitochondriales.
ATE200423T1 (de) * 1995-10-26 2001-04-15 Sanofi Synthelabo Verwendung von 1-(2-naphtylethyl)-4-(3- trifluoromethylphenyl)-1,2,3,6-tetrahydropyridi zur herstellung eines medikaments zur behandlung der amyotrophen lateralsklerode
FR2753379B1 (fr) 1996-09-13 1998-10-30 Rhone Poulenc Rorer Sa Methode de traitement de la sclerose laterale amyotrophique
KR20010022204A (ko) 1997-07-25 2001-03-15 닛뽄카야쿠가부시키가이샤 신경세포 분화 촉진작용을 가진 신규 화합물
CA2317811A1 (en) * 1998-01-09 1999-07-15 Mor-Research Applications Ltd. Treatment of dyskinesias
US6417210B1 (en) 1998-01-09 2002-07-09 Mor-Research Applications Ltd. Treatment of dyskinesias and Parkinson's disease with riluzole and levodopa
FR2785808B1 (fr) * 1998-11-13 2002-12-06 Aventis Laboratoire Association riluzole et alpha-tocopherol
US6872739B1 (en) 1999-06-04 2005-03-29 Vereniging Voor Christelijk Wetenshappelikjk Onderwijs Use of riluzole for the treatment of multiple sclerosis
EP1552831B1 (de) * 1999-06-04 2009-01-07 Vereniging Voor Christelijk Wetenschappelijk Onderwijs Verwendung von Riluzol zur Behandlung Multipler Sklerose
JP2001021609A (ja) * 1999-07-07 2001-01-26 Mitsubishi Electric Corp 半導体集積回路の検査方法
DE19940524C2 (de) * 1999-08-26 2003-06-18 Karl-Heinz Lenzkes Fahrzeugrad, insbesondere für Personenkraftfahrzeuge
FR2801217B1 (fr) * 1999-11-24 2002-12-06 Aventis Pharma Sa Association de riluzole et de gabapentine et son utilisation comme medicament
US6350768B1 (en) 1999-11-24 2002-02-26 Aventis Pharma S.A. Combination of riluzole and of gabapentin and its use as a medicament
US6964982B2 (en) 2000-04-20 2005-11-15 Neurotech Co., Ltd. Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system
IL136687A0 (en) * 2000-06-12 2001-06-14 Mor Research Applic Ltd Pharmaceutical composition for the treatment of multiple sclerosis
WO2002034264A1 (fr) * 2000-10-24 2002-05-02 Mitsubishi Pharma Corporation Medicaments pour traiter la sclerose laterale amyotrophique (sla)
JP2004531691A (ja) * 2000-11-22 2004-10-14 アラーガン、インコーポレイテッド 一過性ナトリウムチャネルと持続性ナトリウムチャネルとを選択的に識別するチャネル遮断薬を同定するためのハイスループットスクリーン
US6479458B1 (en) 2001-11-08 2002-11-12 Allergan, Inc. Targeting the reverse mode of the Na+/Ca2+ exchanger for the treatment of optic neuropathy associated with glaucoma and ischemic optic neuropathy
US7361478B2 (en) * 2001-11-20 2008-04-22 Allergan, Inc. High-throughput screen for identifying selective persistent sodium channels channel blockers
CA2468747C (en) * 2001-12-11 2011-05-31 University Of Virginia Patent Foundation Use of pramipexole to treat amyotrophic lateral sclerosis
DK1551793T3 (en) * 2002-06-19 2016-04-25 Gnt Pharma Co Ltd Tetrafluorobenzyl derivatives and pharmaceutical compositions containing these for the prevention and treatment of acute and chronic neurodegenerative diseases of the central nervous system
EP2526944B1 (de) * 2002-11-15 2016-06-01 Teva Pharmaceutical Industries Limited Verwendung von Rasagilin mit oder ohne Riluzol zur Behandlung amyotropher Lateralsklerose
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US9629817B2 (en) 2005-08-25 2017-04-25 Steven Michael Weiss Reducing myocardial damage and the incidence of arrhythmia arising from loss, reduction or interruption in coronary blood flow
US8518926B2 (en) 2006-04-10 2013-08-27 Knopp Neurosciences, Inc. Compositions and methods of using (R)-pramipexole
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JP2010504338A (ja) * 2006-09-20 2010-02-12 メディベイション ニューロロジー， インコーポレイテッド 筋萎縮性側索硬化症（ＡＬＳ）の治療のための水素化ピリド［４，３−ｂ］インドール
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WO2013096816A1 (en) 2011-12-22 2013-06-27 Biogen Idec Ma Inc. Improved synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
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Family Cites Families (9)

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FR2492258A1 (fr) * 1980-10-17 1982-04-23 Pharmindustrie Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole
US4826860A (en) * 1987-03-16 1989-05-02 Warner-Lambert Company Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents
FR2619713B1 (fr) * 1987-08-25 1990-08-31 Rhone Poulenc Sante Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement des troubles du sommeil et de la depression
US4918090A (en) * 1988-01-25 1990-04-17 Warner-Lambert Company Substituted 2-aminbenzothiazoles and derivatives useful as cerebrovascular agents
US5236940A (en) * 1988-12-15 1993-08-17 Rhone-Poulenc Sante Pharmaceutical compositions, 2-benzothiazolamine derivatives, and their preparation
DE68903484T2 (de) * 1988-12-15 1993-03-18 Rhone Poulenc Sante 2-imino-6-polyfluoralkoxy-benzothiazol-derivate, verfahren zu deren herstellung und arzneimittel, die sie enthalten.
FR2649702B1 (fr) * 1989-07-13 1991-11-22 Rhone Poulenc Sante Derives d'alkylimino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
FR2662160B1 (fr) * 1990-05-18 1992-07-24 Rhone Poulenc Sante Derives d'alkylthio-3 propyl-3 benzothiazoline leur preparation et les medicaments les contenant.
FR2663029B1 (fr) * 1990-06-07 1992-07-31 Rhone Poulenc Sante Derives de benzothiazole, leur preparation et les medicaments les contenant.

Also Published As

Publication number Publication date
DK0627919T3 (da) 1997-05-12
AU666150B2 (en) 1996-02-01
GR3022797T3 (en) 1997-06-30
DE69218255D1 (de) 1997-04-17
ATE149833T1 (de) 1997-03-15
HU9402558D0 (en) 1994-11-28
RU94041223A (ru) 1996-10-20
NO943256L (no) 1994-09-02
JPH07504655A (ja) 1995-05-25
HU217130B (hu) 1999-11-29
CZ212094A3 (en) 1994-12-15
AU2948292A (en) 1993-10-05
DE69218255T2 (de) 1997-09-11
JP2713384B2 (ja) 1998-02-16
CZ281293B6 (cs) 1996-08-14
US5527814A (en) 1996-06-18
WO1993017683A1 (fr) 1993-09-16
EP0627919B1 (de) 1997-03-12
KR950700060A (ko) 1995-01-16
KR100190296B1 (ko) 1999-06-01
FR2688138A1 (fr) 1993-09-10
CA2117466C (fr) 2000-01-25
CA2117466A1 (fr) 1993-09-16
IL103493A0 (en) 1993-03-15
SK279046B6 (sk) 1998-06-03
ES2098558T3 (es) 1997-05-01
NO943256D0 (no) 1994-09-02
EP0558861A1 (de) 1993-09-08
SK104794A3 (en) 1995-05-10
ZA928213B (en) 1993-04-30
UA41879C2 (uk) 2001-10-15
FR2688138B1 (fr) 1995-05-05
MX9206109A (es) 1993-09-01
NO306534B1 (no) 1999-11-22
EP0627919A1 (de) 1994-12-14
HUT70946A (en) 1995-11-28
RU2110260C1 (ru) 1998-05-10

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