IL103493A - שימוש ב - 2 - אמינו - 6 - )טריפלואורומתוקסי( בנזותיאזול להכנתתרופה לטיפול במחלות עצביות-מוטריות - Google Patents

שימוש ב - 2 - אמינו - 6 - )טריפלואורומתוקסי( בנזותיאזול להכנתתרופה לטיפול במחלות עצביות-מוטריות

Info

Publication number
IL103493A
IL103493A IL10349392A IL10349392A IL103493A IL 103493 A IL103493 A IL 103493A IL 10349392 A IL10349392 A IL 10349392A IL 10349392 A IL10349392 A IL 10349392A IL 103493 A IL103493 A IL 103493A
Authority
IL
Israel
Prior art keywords
amino
benzothiazole
treatment
trifluoromethoxy
preparing
Prior art date
Application number
IL10349392A
Other languages
English (en)
Other versions
IL103493A0 (en
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9427427&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL103493(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of IL103493A0 publication Critical patent/IL103493A0/xx
Publication of IL103493A publication Critical patent/IL103493A/he

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
IL10349392A 1992-03-06 1992-10-21 שימוש ב - 2 - אמינו - 6 - )טריפלואורומתוקסי( בנזותיאזול להכנתתרופה לטיפול במחלות עצביות-מוטריות IL103493A (he)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9202696A FR2688138B1 (fr) 1992-03-06 1992-03-06 Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique.

Publications (2)

Publication Number Publication Date
IL103493A0 IL103493A0 (en) 1993-03-15
IL103493A true IL103493A (he) 1996-07-23

Family

ID=9427427

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10349392A IL103493A (he) 1992-03-06 1992-10-21 שימוש ב - 2 - אמינו - 6 - )טריפלואורומתוקסי( בנזותיאזול להכנתתרופה לטיפול במחלות עצביות-מוטריות

Country Status (22)

Country Link
US (1) US5527814A (he)
EP (2) EP0558861A1 (he)
JP (1) JP2713384B2 (he)
KR (1) KR100190296B1 (he)
AT (1) ATE149833T1 (he)
AU (1) AU666150B2 (he)
CA (1) CA2117466C (he)
CZ (1) CZ281293B6 (he)
DE (1) DE69218255T2 (he)
DK (1) DK0627919T3 (he)
ES (1) ES2098558T3 (he)
FR (1) FR2688138B1 (he)
GR (1) GR3022797T3 (he)
HU (1) HU217130B (he)
IL (1) IL103493A (he)
MX (1) MX9206109A (he)
NO (1) NO306534B1 (he)
RU (1) RU2110260C1 (he)
SK (1) SK279046B6 (he)
UA (1) UA41879C2 (he)
WO (1) WO1993017683A1 (he)
ZA (1) ZA928213B (he)

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FR2702148B1 (fr) * 1993-03-05 1995-04-07 Rhone Poulenc Rorer Sa Application d'anticonvulsivants dans le traitement du neuro-sida.
FR2714828B1 (fr) * 1994-01-12 1996-02-02 Rhone Poulenc Rorer Sa Application du riluzole dans le traitement des maladies mitochondriales.
EP0866704B1 (fr) * 1995-10-26 2001-04-11 Sanofi-Synthelabo Utilisation de la 1-(2-napht-2-ylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de la sclerose laterale amyotrophique
FR2753379B1 (fr) * 1996-09-13 1998-10-30 Rhone Poulenc Rorer Sa Methode de traitement de la sclerose laterale amyotrophique
WO1999005091A1 (fr) 1997-07-25 1999-02-04 Nippon Kayaku Kabushiki Kaisha Nouveau compose capable de promouvoir une differenciation neuronale
US6417210B1 (en) 1998-01-09 2002-07-09 Mor-Research Applications Ltd. Treatment of dyskinesias and Parkinson's disease with riluzole and levodopa
EP1043996A2 (en) * 1998-01-09 2000-10-18 Mor-Research Applications Ltd. Treatment of dyskinesias
FR2785808B1 (fr) * 1998-11-13 2002-12-06 Aventis Laboratoire Association riluzole et alpha-tocopherol
DE60041365D1 (de) 1999-06-04 2009-02-26 Vereniging Voor Christelijk Wetenschappelijk Onderwijs Verwendung von Riluzol zur Behandlung Multipler Sklerose
ES2235896T3 (es) * 1999-06-04 2005-07-16 Vereniging Voor Christelijk Wetenschappelijk Onderwijs Uso de riluzol para el tratamaiento de la esclerosis multiple.
JP2001021609A (ja) * 1999-07-07 2001-01-26 Mitsubishi Electric Corp 半導体集積回路の検査方法
DE19940524C2 (de) * 1999-08-26 2003-06-18 Karl-Heinz Lenzkes Fahrzeugrad, insbesondere für Personenkraftfahrzeuge
US6350768B1 (en) 1999-11-24 2002-02-26 Aventis Pharma S.A. Combination of riluzole and of gabapentin and its use as a medicament
FR2801217B1 (fr) * 1999-11-24 2002-12-06 Aventis Pharma Sa Association de riluzole et de gabapentine et son utilisation comme medicament
US6964982B2 (en) 2000-04-20 2005-11-15 Neurotech Co., Ltd. Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system
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WO2002034264A1 (fr) * 2000-10-24 2002-05-02 Mitsubishi Pharma Corporation Medicaments pour traiter la sclerose laterale amyotrophique (sla)
AU2002239329B2 (en) * 2000-11-22 2006-08-10 Allergan, Inc. A high-throughput screen for identifying channel blockers that selectively distinguish transient from persistent sodium channels
US6479458B1 (en) 2001-11-08 2002-11-12 Allergan, Inc. Targeting the reverse mode of the Na+/Ca2+ exchanger for the treatment of optic neuropathy associated with glaucoma and ischemic optic neuropathy
US7361478B2 (en) * 2001-11-20 2008-04-22 Allergan, Inc. High-throughput screen for identifying selective persistent sodium channels channel blockers
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JP5006311B2 (ja) * 2005-05-25 2012-08-22 チョンワエ ファーマ コーポレーション 置換テトラフルオロベンジルアニリン化合物、及びその薬学的に許容される塩の製造方法
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US20100099700A1 (en) * 2006-09-20 2010-04-22 David Hung Hydrogenated pyrido (4,3-b) indoles for treating amyotrophic lateral sclerosis (als)
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MA46716A (fr) 2016-11-03 2019-09-11 Juno Therapeutics Inc Polythérapie de thérapie cellulaire et d'inhibiteur de la microglie
CN111201438A (zh) 2017-06-02 2020-05-26 朱诺治疗学股份有限公司 与和细胞疗法相关的毒性有关的制品和方法
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Also Published As

Publication number Publication date
RU94041223A (ru) 1996-10-20
KR950700060A (ko) 1995-01-16
AU2948292A (en) 1993-10-05
NO943256L (no) 1994-09-02
RU2110260C1 (ru) 1998-05-10
ATE149833T1 (de) 1997-03-15
HU217130B (hu) 1999-11-29
DE69218255D1 (de) 1997-04-17
DE69218255T2 (de) 1997-09-11
MX9206109A (es) 1993-09-01
FR2688138A1 (fr) 1993-09-10
HUT70946A (en) 1995-11-28
US5527814A (en) 1996-06-18
IL103493A0 (en) 1993-03-15
JP2713384B2 (ja) 1998-02-16
EP0558861A1 (fr) 1993-09-08
DK0627919T3 (da) 1997-05-12
CZ212094A3 (en) 1994-12-15
SK279046B6 (sk) 1998-06-03
FR2688138B1 (fr) 1995-05-05
SK104794A3 (en) 1995-05-10
NO943256D0 (no) 1994-09-02
ZA928213B (en) 1993-04-30
AU666150B2 (en) 1996-02-01
CZ281293B6 (cs) 1996-08-14
EP0627919A1 (fr) 1994-12-14
JPH07504655A (ja) 1995-05-25
NO306534B1 (no) 1999-11-22
UA41879C2 (uk) 2001-10-15
CA2117466A1 (fr) 1993-09-16
ES2098558T3 (es) 1997-05-01
EP0627919B1 (fr) 1997-03-12
WO1993017683A1 (fr) 1993-09-16
CA2117466C (fr) 2000-01-25
GR3022797T3 (en) 1997-06-30
KR100190296B1 (ko) 1999-06-01
HU9402558D0 (en) 1994-11-28

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