IL100090A - Crystalline form of N -] 4 -] 5 -) Cyclopentyloxycarbonyl (amino - 1 - methyl - indole - 3 - ylmethyl [- 3 - methoxybenzoyl [- 2 - methylbenzene] - Google Patents

Crystalline form of N -] 4 -] 5 -) Cyclopentyloxycarbonyl (amino - 1 - methyl - indole - 3 - ylmethyl [- 3 - methoxybenzoyl [- 2 - methylbenzene]

Info

Publication number
IL100090A
IL100090A IL10009091A IL10009091A IL100090A IL 100090 A IL100090 A IL 100090A IL 10009091 A IL10009091 A IL 10009091A IL 10009091 A IL10009091 A IL 10009091A IL 100090 A IL100090 A IL 100090A
Authority
IL
Israel
Prior art keywords
methoxybenzoyl
methyl
indol
amino
ylmethyl
Prior art date
Application number
IL10009091A
Other languages
English (en)
Hebrew (he)
Other versions
IL100090A0 (en
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of IL100090A0 publication Critical patent/IL100090A0/xx
Publication of IL100090A publication Critical patent/IL100090A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL10009091A 1990-12-12 1991-11-19 Crystalline form of N -] 4 -] 5 -) Cyclopentyloxycarbonyl (amino - 1 - methyl - indole - 3 - ylmethyl [- 3 - methoxybenzoyl [- 2 - methylbenzene] IL100090A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909027018A GB9027018D0 (en) 1990-12-12 1990-12-12 Heterocyclic compounds

Publications (2)

Publication Number Publication Date
IL100090A0 IL100090A0 (en) 1992-08-18
IL100090A true IL100090A (en) 1996-09-12

Family

ID=10686919

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10009091A IL100090A (en) 1990-12-12 1991-11-19 Crystalline form of N -] 4 -] 5 -) Cyclopentyloxycarbonyl (amino - 1 - methyl - indole - 3 - ylmethyl [- 3 - methoxybenzoyl [- 2 - methylbenzene]

Country Status (28)

Country Link
US (1) US5294636A (da)
EP (1) EP0490649B1 (da)
JP (1) JP2650807B2 (da)
KR (1) KR100194479B1 (da)
CN (2) CN1032469C (da)
AP (1) AP286A (da)
AT (1) ATE145199T1 (da)
AU (1) AU656344B2 (da)
CA (1) CA2056067C (da)
CZ (1) CZ288151B6 (da)
DE (1) DE69123123T2 (da)
DK (1) DK0490649T3 (da)
ES (1) ES2094797T3 (da)
FI (1) FI101296B (da)
GB (2) GB9027018D0 (da)
GR (1) GR3021605T3 (da)
HK (1) HK81497A (da)
HU (2) HU213109B (da)
IE (1) IE914316A1 (da)
IL (1) IL100090A (da)
MX (1) MX9102475A (da)
MY (1) MY108629A (da)
NZ (1) NZ240940A (da)
PH (1) PH30041A (da)
RU (1) RU2107682C1 (da)
SK (1) SK279018B6 (da)
TW (1) TW222264B (da)
ZA (1) ZA919772B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE113581T1 (de) * 1990-05-04 1994-11-15 Ciba Geigy Ag Substituierte indole.
IL100091A (en) * 1990-12-12 1998-08-16 Zeneca Ltd Pharmaceutical preparations containing the physical form of [4] 5) Cyclopentyloxycarbyl (amino 1 methyl indole 3 methyl methyl [3 methoxybenzoyl [2 methylbenzole)
GB9119001D0 (en) * 1991-09-05 1991-10-23 Ici Plc Pharmaceutical agents
GR1001368B (el) * 1992-10-08 1993-10-29 Ici Plc Φαρμακευτικοί φορείς.
DE4235133A1 (de) * 1992-10-19 1994-04-21 Bayer Ag Kristallines (R)-(-)-2-Cycloheptyl-N-methylsulfonyl-[4-(2-chinolinyl-methoxy)-phenyl]-acetamid
IL111080A (en) * 1993-10-01 1999-08-17 Astra Ab Method for treating a finely divided powder medicament
IS1736B (is) 1993-10-01 1999-12-30 Astra Ab Aðferð og tæki sem stuðla að aukinni samloðun agna
GB9723985D0 (en) * 1997-11-14 1998-01-14 Zeneca Ltd Pharmaceutical compositions
GB9726735D0 (en) * 1997-12-18 1998-02-18 Zeneca Ltd Pharmaceutical compositions
IL139243A0 (en) * 2000-10-24 2001-11-25 Internat Specialty Products Is Ethanolate of zafirlukast, process for manufacture and pharmaceutical compositions thereof
TWI353979B (en) * 2002-04-10 2011-12-11 Nippon Zoki Pharmaceutical Co Novel crystal form of 5-hydroxy-1-methylhydantoin
US20050026882A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a leukotriene receptor antagonist for treatment of asthma or chronic obstructive pulmonary disease
US20090317476A1 (en) * 2003-07-31 2009-12-24 Robinson Cynthia B Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a leukotriene receptor antagonist for treatment of asthma or chronic obstructive pulmonary disease
US20050113410A1 (en) * 2003-11-03 2005-05-26 Mark Tawa Pharmaceutical salts of zafirlukast
EP1855651A4 (en) * 2005-03-03 2011-06-15 Elan Pharma Int Ltd NANOPARTICULAR COMPOSITIONS OF HETEROCYCLIC AMIDE DERIVATIVES
US20070197467A1 (en) * 2006-02-06 2007-08-23 Srinivasulu Rangineni Zafirlukast compositions
US20090012146A1 (en) * 2007-07-02 2009-01-08 Giridhar Reddy Buggana Solubility-enhanced pharmaceutical compositions comprising zafirlukast
CA2695008A1 (en) * 2007-07-30 2009-02-05 Auspex Pharmaceuticals, Inc. Substituted indoles
TWI469965B (zh) * 2008-12-22 2015-01-21 Ono Pharmaceutical Co 乙炔基吲哚化合物
WO2014012954A1 (en) 2012-07-18 2014-01-23 Takeda Gmbh Treatment of partly controlled or uncontrolled severe asthma
CN103396353B (zh) * 2013-08-23 2015-05-20 海南通用三洋药业有限公司 一种扎鲁司特无定型态及其制备方法
CA2936332A1 (en) 2014-01-22 2015-07-30 Takeda Gmbh Treatment of partly controlled or uncontrolled severe asthma with a pde4 inhibitor (and in combination with a leukotriene modifier)
PT109030B (pt) 2015-12-15 2019-09-25 Hovione Farmaciência, S.A. Preparação de partículas inaláveis de zafirlucaste
WO2018140858A1 (en) 2017-01-30 2018-08-02 Western New England University Thiol isomerases inhibitors and use thereof
WO2022243942A1 (en) 2021-05-19 2022-11-24 Quercis Pharma AG Quercetin-containing compositions for use in treating amyotrophic lateral sclerosis
WO2023214391A1 (en) 2022-05-06 2023-11-09 Quercis Pharma AG Method for treating cancers and neurological diseases using quercetin-containing compositions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4161516A (en) * 1975-07-25 1979-07-17 Fisons Limited Composition for treating airway disease
GB8607294D0 (en) * 1985-04-17 1986-04-30 Ici America Inc Heterocyclic amide derivatives

Also Published As

Publication number Publication date
ATE145199T1 (de) 1996-11-15
EP0490649B1 (en) 1996-11-13
FI915825A0 (fi) 1991-12-11
IE914316A1 (en) 1992-06-17
CN1074411C (zh) 2001-11-07
GB2250743B (en) 1995-02-15
HU211125A9 (en) 1995-10-30
FI915825A (fi) 1992-06-13
KR920012031A (ko) 1992-07-25
HU913863D0 (en) 1992-02-28
GB2250743A (en) 1992-06-17
RU2107682C1 (ru) 1998-03-27
GB9027018D0 (en) 1991-01-30
HUT60717A (en) 1992-10-28
CA2056067A1 (en) 1992-06-13
AU656344B2 (en) 1995-02-02
DE69123123T2 (de) 1997-03-06
JP2650807B2 (ja) 1997-09-10
DE69123123D1 (de) 1996-12-19
JPH04266872A (ja) 1992-09-22
HU213109B (en) 1997-02-28
MY108629A (en) 1996-10-31
CA2056067C (en) 2001-09-04
ZA919772B (en) 1992-09-30
DK0490649T3 (da) 1997-04-21
ES2094797T3 (es) 1997-02-01
CN1032469C (zh) 1996-08-07
US5294636A (en) 1994-03-15
PH30041A (en) 1996-11-08
AP9100341A0 (en) 1992-01-31
GR3021605T3 (en) 1997-02-28
FI101296B1 (fi) 1998-05-29
AU8899591A (en) 1992-06-18
CN1063100A (zh) 1992-07-29
KR100194479B1 (ko) 1999-06-15
IL100090A0 (en) 1992-08-18
CS375891A3 (en) 1992-06-17
CZ288151B6 (en) 2001-05-16
EP0490649A1 (en) 1992-06-17
HK81497A (en) 1997-06-27
NZ240940A (en) 1994-05-26
GB9126353D0 (en) 1992-02-12
MX9102475A (es) 1992-06-01
SK279018B6 (sk) 1998-05-06
FI101296B (fi) 1998-05-29
AP286A (en) 1993-09-26
CN1148491A (zh) 1997-04-30
TW222264B (da) 1994-04-11

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