IE891667L - Aromatic and heterocyclic carboxamide derivatives as¹antineoplastic agents - Google Patents

Aromatic and heterocyclic carboxamide derivatives as¹antineoplastic agents

Info

Publication number
IE891667L
IE891667L IE891667A IE166789A IE891667L IE 891667 L IE891667 L IE 891667L IE 891667 A IE891667 A IE 891667A IE 166789 A IE166789 A IE 166789A IE 891667 L IE891667 L IE 891667L
Authority
IE
Ireland
Prior art keywords
agents
aromatic
carboxamide derivatives
heterocyclic carboxamide
heterocyclic
Prior art date
Application number
IE891667A
Other languages
English (en)
Original Assignee
Martin Francis Finn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Martin Francis Finn filed Critical Martin Francis Finn
Publication of IE891667L publication Critical patent/IE891667L/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Graft Or Block Polymers (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IE891667A 1988-05-24 1989-05-23 Aromatic and heterocyclic carboxamide derivatives as¹antineoplastic agents IE891667L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19803488A 1988-05-24 1988-05-24

Publications (1)

Publication Number Publication Date
IE891667L true IE891667L (en) 1989-11-24

Family

ID=22731735

Family Applications (1)

Application Number Title Priority Date Filing Date
IE891667A IE891667L (en) 1988-05-24 1989-05-23 Aromatic and heterocyclic carboxamide derivatives as¹antineoplastic agents

Country Status (25)

Country Link
EP (1) EP0343893B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH0678331B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR910006864B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1023700C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE79114T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU601905B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1328871C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD283815A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE68902358T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK249389A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2043012T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI892498A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3005844T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU202507B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE891667L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL90337A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX173140B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY106035A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO172389C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ229234A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL154875B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT90622B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (1) SU1681728A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU47019B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA893862B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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JP2790299B2 (ja) * 1989-02-01 1998-08-27 保土谷化学工業株式会社 ペンゾチアゾール誘導体
US5262400A (en) * 1991-06-20 1993-11-16 Merck & Co., Inc. 4α-substituted avermectin derivatives
US6100423A (en) * 1995-08-30 2000-08-08 G. D. Searle & Co. Amino benzenepropanoic acid compounds and derivatives thereof
US6028223A (en) 1995-08-30 2000-02-22 G. D. Searle & Co. Meta-guanidine, urea, thiourea or azacyclic amino benzoic acid compounds and derivatives thereof
US5716281A (en) * 1995-11-27 1998-02-10 Sega Enterprises, Ltd. Game apparatus using a vehicle with an optical image synthesizing system
TW513418B (en) * 1996-07-31 2002-12-11 Otsuka Pharma Co Ltd Thiazole derivatives, their production and use
DE69833224T2 (de) 1997-11-10 2006-09-28 Bristol-Myers Squibb Co. Benzothiazole als protein tyrosin-kinase inhibitoren
SI0928793T1 (en) * 1998-01-02 2002-10-31 F. Hoffmann-La Roche Ag Thiazole derivatives
AU3406599A (en) * 1998-04-09 1999-11-01 Institut Fur Diagnostikforschung Gmbh An Der Freien Universitat Berlin Novel benzyl guanidine derivatives for therapy and (in-vivo) and (in-vitro) diagnosis
DK1303272T3 (da) 2000-06-21 2008-05-26 Hoffmann La Roche Benzothiazolderivater til behandling af Alzheimers sygdom og Parkinsons sygdom
US6620811B2 (en) * 2001-11-19 2003-09-16 Hoffmann-La Roche Inc. Isonicotin- and nicotinamide derivatives of benzothiazoles
US6599901B1 (en) * 2001-11-19 2003-07-29 Hoffman-La Roche Inc. Pyridone substituted benzothiazole derivatives
US6624163B2 (en) * 2001-11-29 2003-09-23 Hoffman-La Roche Inc. Benzothiazole derivatives
GB0130868D0 (en) * 2001-12-24 2002-02-06 Univ Strathclyde New compounds
CN100357283C (zh) * 2002-04-02 2007-12-26 中国科学院上海药物研究所 一类甲硫氨酰氨肽酶抑制剂
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
WO2004101558A1 (en) * 2003-05-13 2004-11-25 F. Hoffmann-La Roche Ag 2-imidazo-benzothiazoles as adenosine receptor ligands
ES2301991T3 (es) * 2003-05-19 2008-07-01 F. Hoffmann-La Roche Ag Derivados de benzotiazol como ligandos del receptor de adenosina.
BRPI0410754A (pt) * 2003-05-21 2006-06-27 Hoffmann La Roche derivados de benzotiazol e uso desses derivados no tratamento de doenças relacionadas com o receptor de adenosina a2a
ES2307015T3 (es) * 2003-05-30 2008-11-16 F. Hoffmann-La Roche Ag Derivados de benzotiazol y su empleo en el tratamiento de enfermedades relacionadas con el receptor de la adenosina a2a.
CN100591679C (zh) * 2003-07-28 2010-02-24 詹森药业有限公司 苯并咪唑、苯并噻唑和苯并唑衍生物及其作为lta4h调节剂的应用
ATE382619T1 (de) 2004-05-24 2008-01-15 Hoffmann La Roche 4-hydroxy-4-methylpiperidin-1-carbonsäure-(4- methoxy-7-morpholin-4-ylbenzothiazol-2-yl)-amid
KR100818028B1 (ko) * 2004-07-22 2008-03-31 에프. 호프만-라 로슈 아게 치환된 벤조티아졸
EP1773827B1 (en) * 2004-07-22 2010-02-17 F.Hoffmann-La Roche Ag Benzothiazole derivatives
ATE400557T1 (de) 2004-11-05 2008-07-15 Hoffmann La Roche Verfahren zur herstellung von isonikotinsäurederivaten
CN101180299B (zh) 2005-03-23 2010-12-15 弗·哈夫曼-拉罗切有限公司 作为mglur2拮抗剂的乙炔基-吡唑并嘧啶衍生物
AU2006298829B2 (en) 2005-09-27 2011-03-03 F. Hoffmann-La Roche Ag Oxadiazolyl pyrazolo-pyrimidines as mGluR2 antagonists
CN101405278A (zh) * 2006-03-15 2009-04-08 4Sc股份公司 新颖的杂环NF-κB抑制剂
GB0619325D0 (en) 2006-09-30 2006-11-08 Univ Strathclyde New compounds
US20110178070A1 (en) * 2008-06-24 2011-07-21 Takeda Pharmaceutical Company Limited PI3K/mTOR INHIBITORS
US9499790B2 (en) 2010-08-26 2016-11-22 Kyoto University Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells
BR112014007599A2 (pt) * 2011-09-30 2017-04-11 Kineta Inc compostos anti-virais
US9587220B2 (en) 2012-01-27 2017-03-07 Kyoto University Method for inducing cardiac differentiation of pluripotent stem cell
EP2966166B1 (en) 2013-03-08 2019-04-03 Kyoto University Promoter of differentiation of pluripotent stem cell into myocardium, which comprises egf receptor inhibitor
JP6333830B2 (ja) * 2013-09-13 2018-05-30 国立大学法人京都大学 多能性幹細胞の心筋分化を促進する化合物
JP6651218B2 (ja) 2014-05-30 2020-02-19 国立大学法人京都大学 低分子化合物を用いた多能性幹細胞の心筋分化誘導法
CN109776486A (zh) * 2019-02-26 2019-05-21 武汉松石科技股份有限公司 一种硫酸亚丙酯的制备方法
CN110590735B (zh) * 2019-09-30 2021-07-23 江苏国泰超威新材料有限公司 一种环状硫酸酯的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61225168A (ja) * 1985-03-30 1986-10-06 Nippon Tokushu Noyaku Seizo Kk 新規ベンズアミド、その製法及び殺虫剤
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
GB8611606D0 (en) * 1986-05-13 1986-06-18 Fbc Ltd Fungicides

Also Published As

Publication number Publication date
NO172389B (no) 1993-04-05
ZA893862B (en) 1991-01-30
CN1023700C (zh) 1994-02-09
SU1681728A3 (ru) 1991-09-30
YU105989A (en) 1990-08-31
JPH0678331B2 (ja) 1994-10-05
FI892498A0 (fi) 1989-05-23
CN1037898A (zh) 1989-12-13
CA1328871C (en) 1994-04-26
IL90337A0 (en) 1989-12-15
YU47019B (sh) 1994-11-15
EP0343893B1 (en) 1992-08-05
AU601905B2 (en) 1990-09-20
DE68902358D1 (de) 1992-09-10
HUT51606A (en) 1990-05-28
HU202507B (en) 1991-03-28
PL154875B1 (en) 1991-09-30
DE68902358T2 (de) 1992-12-10
DK249389D0 (da) 1989-05-23
NO892059L (no) 1989-11-27
MX16158A (es) 1993-06-01
KR890017248A (ko) 1989-12-15
PL279613A1 (en) 1989-11-27
EP0343893A1 (en) 1989-11-29
JPH0217181A (ja) 1990-01-22
MX173140B (es) 1994-02-02
NO892059D0 (no) 1989-05-23
MY106035A (en) 1995-03-31
PT90622B (pt) 1994-10-31
FI892498A7 (fi) 1989-11-25
ES2043012T3 (es) 1993-12-16
NZ229234A (en) 1990-09-26
DK249389A (da) 1989-11-27
ATE79114T1 (de) 1992-08-15
PT90622A (pt) 1989-11-30
NO172389C (no) 1993-07-14
DD283815A5 (de) 1990-10-24
AU3509889A (en) 1989-11-30
GR3005844T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-06-07
KR910006864B1 (ko) 1991-09-09

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