AU1613488A - Acyl hydrazine derivatives - Google Patents

Acyl hydrazine derivatives

Info

Publication number
AU1613488A
AU1613488A AU16134/88A AU1613488A AU1613488A AU 1613488 A AU1613488 A AU 1613488A AU 16134/88 A AU16134/88 A AU 16134/88A AU 1613488 A AU1613488 A AU 1613488A AU 1613488 A AU1613488 A AU 1613488A
Authority
AU
Australia
Prior art keywords
hydrazine derivatives
acyl hydrazine
acyl
derivatives
hydrazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU16134/88A
Inventor
Pierre Binet
Herve Galons
Marcel Miocque
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LES LABORATOIRES MERAM
Original Assignee
LES LABORATOIRES MERAM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LES LABORATOIRES MERAM filed Critical LES LABORATOIRES MERAM
Publication of AU1613488A publication Critical patent/AU1613488A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C07C251/86—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/16—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of hydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AU16134/88A 1987-05-14 1988-05-13 Acyl hydrazine derivatives Abandoned AU1613488A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8706801A FR2615188B1 (en) 1987-05-14 1987-05-14 HYDRAZINE DERIVATIVES, PROCESS FOR OBTAINING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
FR8706801 1987-05-14

Publications (1)

Publication Number Publication Date
AU1613488A true AU1613488A (en) 1988-11-17

Family

ID=9351109

Family Applications (1)

Application Number Title Priority Date Filing Date
AU16134/88A Abandoned AU1613488A (en) 1987-05-14 1988-05-13 Acyl hydrazine derivatives

Country Status (15)

Country Link
EP (1) EP0294258A1 (en)
JP (1) JPS6463561A (en)
KR (1) KR880013881A (en)
CN (1) CN88102858A (en)
AU (1) AU1613488A (en)
DK (1) DK265788A (en)
FI (1) FI882267A (en)
FR (1) FR2615188B1 (en)
MA (1) MA21273A1 (en)
NO (1) NO882030L (en)
NZ (1) NZ224617A (en)
OA (1) OA08734A (en)
SU (1) SU1672929A3 (en)
TN (1) TNSN88045A1 (en)
ZA (1) ZA883301B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9783521B2 (en) 2008-08-05 2017-10-10 Omeros Corporation PDE10 inhibitors and related compositions and methods

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5623072A (en) * 1994-10-11 1997-04-22 Monsanto Company 3-phenylpyridazines, herbicidal compositions and uses thereof
KR100736838B1 (en) * 2001-05-03 2007-07-10 씨제이 주식회사 Novel catechol N-methylhydrazide derivatives and process for preparation thereof
KR100866285B1 (en) * 2002-09-06 2008-10-31 씨제이제일제당 (주) Novel catechol hydrazide derivatives and process for preparation thereof
DE10346913A1 (en) 2003-10-09 2005-05-04 Merck Patent Gmbh acylhydrazone
CN100355748C (en) * 2004-09-20 2007-12-19 中国人民解放军军事医学科学院毒物药物研究所 Aromatic hydrazide kind compound and its use in preparation of immune inhibitor
WO2008097504A2 (en) 2007-02-02 2008-08-14 Redpoint Bio Corporation Use of a trpm5 inhibitor to regulate insulin and glp-1 release

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654294A (en) * 1967-07-27 1972-04-04 R & L Molecular Research Ltd Certain isothiazolylacetylenemercaptides
US3708591A (en) * 1970-03-18 1973-01-02 Rohm & Haas Certain formylhydrazones used as aphicides
US3753680A (en) * 1970-05-14 1973-08-21 Stauffer Chemical Co Arylidene semicarbazones and their utility as herbicides
DD107255A1 (en) * 1973-06-14 1974-07-20
US3867425A (en) * 1974-01-09 1975-02-18 American Cyanamid Co Substituted benzyl carbazic acid esters
JPS5459326A (en) * 1977-10-18 1979-05-12 Nissan Chem Ind Ltd Insecticide
FR2457288A2 (en) * 1978-09-12 1980-12-19 Rhone Poulenc Agrochimie NOVEL OXADIAZOLINE-1,3,4-ONE-5 DERIVATIVES, THEIR PREPARATION AND INSECTICIDE COMPOSITIONS CONTAINING THEM
HU190795B (en) * 1982-05-04 1986-11-28 Egyt Gyogyszervegyeszeti Gyar,Hu Process for producing carbazinic derivatives and compositions containing them for increasing weight yield
DE3624349A1 (en) * 1986-07-17 1988-01-28 Schering Ag SUBSTITUTED HYDRAZONE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A PEST CONTROL

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9783521B2 (en) 2008-08-05 2017-10-10 Omeros Corporation PDE10 inhibitors and related compositions and methods

Also Published As

Publication number Publication date
NO882030D0 (en) 1988-05-10
MA21273A1 (en) 1988-12-31
EP0294258A1 (en) 1988-12-07
ZA883301B (en) 1988-11-14
TNSN88045A1 (en) 1990-07-10
DK265788A (en) 1988-11-15
FR2615188B1 (en) 1989-11-17
KR880013881A (en) 1988-12-22
FR2615188A1 (en) 1988-11-18
FI882267A (en) 1988-11-15
DK265788D0 (en) 1988-05-13
OA08734A (en) 1989-03-31
FI882267A0 (en) 1988-05-13
CN88102858A (en) 1988-12-14
NZ224617A (en) 1991-02-26
SU1672929A3 (en) 1991-08-23
NO882030L (en) 1988-11-15
JPS6463561A (en) 1989-03-09

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