ZA883301B - Hydrazine derivatives,process for their preparation and pharmaceutical compositions in which they are present - Google Patents

Hydrazine derivatives,process for their preparation and pharmaceutical compositions in which they are present

Info

Publication number
ZA883301B
ZA883301B ZA883301A ZA883301A ZA883301B ZA 883301 B ZA883301 B ZA 883301B ZA 883301 A ZA883301 A ZA 883301A ZA 883301 A ZA883301 A ZA 883301A ZA 883301 B ZA883301 B ZA 883301B
Authority
ZA
South Africa
Prior art keywords
preparation
present
pharmaceutical compositions
hydrazine derivatives
hydrazine
Prior art date
Application number
ZA883301A
Inventor
Miocque Marcel
Binet Pierre
Galons Herve
Original Assignee
Les Laboratoires Meram
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Les Laboratoires Meram filed Critical Les Laboratoires Meram
Publication of ZA883301B publication Critical patent/ZA883301B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C07C251/86—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to carbon atoms of six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/16—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of hydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
ZA883301A 1987-05-14 1988-05-10 Hydrazine derivatives,process for their preparation and pharmaceutical compositions in which they are present ZA883301B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8706801A FR2615188B1 (en) 1987-05-14 1987-05-14 HYDRAZINE DERIVATIVES, PROCESS FOR OBTAINING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

Publications (1)

Publication Number Publication Date
ZA883301B true ZA883301B (en) 1988-11-14

Family

ID=9351109

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA883301A ZA883301B (en) 1987-05-14 1988-05-10 Hydrazine derivatives,process for their preparation and pharmaceutical compositions in which they are present

Country Status (15)

Country Link
EP (1) EP0294258A1 (en)
JP (1) JPS6463561A (en)
KR (1) KR880013881A (en)
CN (1) CN88102858A (en)
AU (1) AU1613488A (en)
DK (1) DK265788A (en)
FI (1) FI882267A (en)
FR (1) FR2615188B1 (en)
MA (1) MA21273A1 (en)
NO (1) NO882030L (en)
NZ (1) NZ224617A (en)
OA (1) OA08734A (en)
SU (1) SU1672929A3 (en)
TN (1) TNSN88045A1 (en)
ZA (1) ZA883301B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5623072A (en) * 1994-10-11 1997-04-22 Monsanto Company 3-phenylpyridazines, herbicidal compositions and uses thereof
KR100736838B1 (en) * 2001-05-03 2007-07-10 씨제이 주식회사 Novel catechol N-methylhydrazide derivatives and process for preparation thereof
KR100866285B1 (en) * 2002-09-06 2008-10-31 씨제이제일제당 (주) Novel catechol hydrazide derivatives and process for preparation thereof
DE10346913A1 (en) 2003-10-09 2005-05-04 Merck Patent Gmbh acylhydrazone
CN100355748C (en) * 2004-09-20 2007-12-19 中国人民解放军军事医学科学院毒物药物研究所 Aromatic hydrazide kind compound and its use in preparation of immune inhibitor
US8193168B2 (en) 2007-02-02 2012-06-05 Redpoint Bio Corporation Use of a TRPM5 inhibitor to regulate insulin and GLP-1 release
EP2310016B1 (en) 2008-08-05 2017-10-04 Omeros Corporation Pde10 inhibitors and related compositions and methods

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654294A (en) * 1967-07-27 1972-04-04 R & L Molecular Research Ltd Certain isothiazolylacetylenemercaptides
US3708591A (en) * 1970-03-18 1973-01-02 Rohm & Haas Certain formylhydrazones used as aphicides
US3753680A (en) * 1970-05-14 1973-08-21 Stauffer Chemical Co Arylidene semicarbazones and their utility as herbicides
DD107255A1 (en) * 1973-06-14 1974-07-20
US3867425A (en) * 1974-01-09 1975-02-18 American Cyanamid Co Substituted benzyl carbazic acid esters
JPS5459326A (en) * 1977-10-18 1979-05-12 Nissan Chem Ind Ltd Insecticide
FR2457288A2 (en) * 1978-09-12 1980-12-19 Rhone Poulenc Agrochimie NOVEL OXADIAZOLINE-1,3,4-ONE-5 DERIVATIVES, THEIR PREPARATION AND INSECTICIDE COMPOSITIONS CONTAINING THEM
HU190795B (en) * 1982-05-04 1986-11-28 Egyt Gyogyszervegyeszeti Gyar,Hu Process for producing carbazinic derivatives and compositions containing them for increasing weight yield
DE3624349A1 (en) * 1986-07-17 1988-01-28 Schering Ag SUBSTITUTED HYDRAZONE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A PEST CONTROL

Also Published As

Publication number Publication date
JPS6463561A (en) 1989-03-09
DK265788A (en) 1988-11-15
AU1613488A (en) 1988-11-17
SU1672929A3 (en) 1991-08-23
OA08734A (en) 1989-03-31
CN88102858A (en) 1988-12-14
MA21273A1 (en) 1988-12-31
FI882267A (en) 1988-11-15
NO882030L (en) 1988-11-15
NO882030D0 (en) 1988-05-10
TNSN88045A1 (en) 1990-07-10
NZ224617A (en) 1991-02-26
DK265788D0 (en) 1988-05-13
FR2615188A1 (en) 1988-11-18
FI882267A0 (en) 1988-05-13
FR2615188B1 (en) 1989-11-17
EP0294258A1 (en) 1988-12-07
KR880013881A (en) 1988-12-22

Similar Documents

Publication Publication Date Title
IL92798A0 (en) Benzimidazole derivatives,process for their preparation and pharmaceutical compositions containing them
GR3032732T3 (en) Amido-3-pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them.
IL88363A0 (en) Fluorocytidine derivatives,their production and pharmaceutical compositions containing them
IL86877A (en) Carbazole derivatives,their preparation and pharmaceutical compositions containing them
IL103126A (en) 5-amino-4-hydroxyhexanoic acid derivatives, process for their preparation and pharmaceutical compositions containing them
IL85247A (en) Polyamine derivatives,process for their preparation and pharmaceutical compositions containing them
IL87949A0 (en) Dideoxycytidine derivatives,their preparation and pharmaceutical compositions containing them
IL87532A (en) Aristeromycin/adenosine derivatives, process for their preparation and pharmaceutical compositions containing them
IL87181A (en) Aminoalkoxyphenyl derivatives, their preparation and pharmaceutical and veterinary compositions containing them
GR3021933T3 (en) Pyridazine derivatives, process for their preparation and pharmaceutical compositions containing them
ZA887607B (en) 2,2-dimethylchromene derivatives,process for their preparation and pharmaceutical compositions in which they are present
IL98812A0 (en) Purine derivatives,process for their preparation and pharmaceutical compositions containing them
IL86411A (en) Catecholamine derivatives,their preparation and pharmaceutical compositions containing them
IL73888A (en) Ortho-condensed pyrrole derivatives,process for the preparation thereof and pharmaceutical compositions comprising the same
IL97656A0 (en) Purine derivatives,process for their preparation and pharmaceutical compositions comprising them
IL88138A0 (en) Purine derivatives,their preparation and pharmaceutical compositions containing them
IL87856A0 (en) Alkadiene derivatives,process for their preparation and pharmaceutical compositions containing them
EP0285089A3 (en) 4-thioquinazoline derivatives, processes for their preparation and pharmaceutical compositions
IL94485A0 (en) Purine derivatives,process for their preparation and pharmaceutical compositions containing them
ZA883301B (en) Hydrazine derivatives,process for their preparation and pharmaceutical compositions in which they are present
ZA899955B (en) Benzene derivatives,their preparation and pharmaceutical compositions in which they are present
IL87016A (en) Phenylpiperidine derivatives, their preparation and pharmaceutical compositions containing them
IL85738A0 (en) Nucleoside derivatives,their preparation and pharmaceutical compositions containing them
IL82332A (en) Substituted 2-phenylbenzothiazin(-3-)one derivatives,process for their preparation and pharmaceutical compositions containing them
AU1833888A (en) 2,2-dimethylchroman-3-ol derivatives, process for their preparation and pharmaceutical compositions in which they are present