ZA893862B - Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents - Google Patents

Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents

Info

Publication number
ZA893862B
ZA893862B ZA893862A ZA893862A ZA893862B ZA 893862 B ZA893862 B ZA 893862B ZA 893862 A ZA893862 A ZA 893862A ZA 893862 A ZA893862 A ZA 893862A ZA 893862 B ZA893862 B ZA 893862B
Authority
ZA
South Africa
Prior art keywords
aromatic
antineoplastic agents
carboxamide derivatives
heterocyclic carboxamide
heterocyclic
Prior art date
Application number
ZA893862A
Other languages
English (en)
Inventor
Anton Franz Josef Fliri
Franz Josef Fliri Anton
Rodney Caughren Schnur
Caughren Schnur Rodney
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA893862B publication Critical patent/ZA893862B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Graft Or Block Polymers (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA893862A 1988-05-24 1989-05-23 Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents ZA893862B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19803488A 1988-05-24 1988-05-24

Publications (1)

Publication Number Publication Date
ZA893862B true ZA893862B (en) 1991-01-30

Family

ID=22731735

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA893862A ZA893862B (en) 1988-05-24 1989-05-23 Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents

Country Status (25)

Country Link
EP (1) EP0343893B1 (xx)
JP (1) JPH0678331B2 (xx)
KR (1) KR910006864B1 (xx)
CN (1) CN1023700C (xx)
AT (1) ATE79114T1 (xx)
AU (1) AU601905B2 (xx)
CA (1) CA1328871C (xx)
DD (1) DD283815A5 (xx)
DE (1) DE68902358T2 (xx)
DK (1) DK249389A (xx)
ES (1) ES2043012T3 (xx)
FI (1) FI892498A (xx)
GR (1) GR3005844T3 (xx)
HU (1) HU202507B (xx)
IE (1) IE891667L (xx)
IL (1) IL90337A0 (xx)
MX (1) MX173140B (xx)
MY (1) MY106035A (xx)
NO (1) NO172389C (xx)
NZ (1) NZ229234A (xx)
PL (1) PL154875B1 (xx)
PT (1) PT90622B (xx)
SU (1) SU1681728A3 (xx)
YU (1) YU47019B (xx)
ZA (1) ZA893862B (xx)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2790299B2 (ja) * 1989-02-01 1998-08-27 保土谷化学工業株式会社 ペンゾチアゾール誘導体
US5262400A (en) * 1991-06-20 1993-11-16 Merck & Co., Inc. 4α-substituted avermectin derivatives
US6100423A (en) * 1995-08-30 2000-08-08 G. D. Searle & Co. Amino benzenepropanoic acid compounds and derivatives thereof
BR9610422A (pt) 1995-08-30 1999-07-13 Searle & Co Derivados de meta-guanidina uréia tiouréia ou ácido aminobenzóico azacíclico como antagonistas de integrina
US5716281A (en) * 1995-11-27 1998-02-10 Sega Enterprises, Ltd. Game apparatus using a vehicle with an optical image synthesizing system
TW513418B (en) * 1996-07-31 2002-12-11 Otsuka Pharma Co Ltd Thiazole derivatives, their production and use
ES2256969T3 (es) 1997-11-10 2006-07-16 Bristol-Myers Squibb Company Compuestos de benzotiazol inhibidores de proteina tirosina qauinasa.
SI0928793T1 (en) * 1998-01-02 2002-10-31 F. Hoffmann-La Roche Ag Thiazole derivatives
AU3406599A (en) * 1998-04-09 1999-11-01 Institut Fur Diagnostikforschung Gmbh An Der Freien Universitat Berlin Novel benzyl guanidine derivatives for therapy and (in-vivo) and (in-vitro) diagnosis
PL207384B1 (pl) 2000-06-21 2010-12-31 Hoffmann La Roche Pochodne benzotiazolu, sposób ich wytwarzania, lek i ich zastosowanie do wytwarzania leku
US6624163B2 (en) * 2001-11-29 2003-09-23 Hoffman-La Roche Inc. Benzothiazole derivatives
GB0130868D0 (en) * 2001-12-24 2002-02-06 Univ Strathclyde New compounds
CN100357283C (zh) * 2002-04-02 2007-12-26 中国科学院上海药物研究所 一类甲硫氨酰氨肽酶抑制剂
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
PL1753760T3 (pl) 2004-05-24 2008-06-30 Hoffmann La Roche (4-metoksy-7-morffolin-4-ylobenzatiazol-2-ilo)amid kwasu 4-hydroksy-4-metylopiperydyno-1-karboksylowego
EP1812392B1 (en) 2004-11-05 2008-07-09 F.Hoffmann-La Roche Ag Process for preparation of isonicotinic acid derivatives
CN101180299B (zh) 2005-03-23 2010-12-15 弗·哈夫曼-拉罗切有限公司 作为mglur2拮抗剂的乙炔基-吡唑并嘧啶衍生物
ES2340321T3 (es) 2005-09-27 2010-06-01 F.Hoffmann-La Roche Ag Oxadiazolilpirazolo-pirimidinas, como antagonistas de mglur2.
CN101405278A (zh) * 2006-03-15 2009-04-08 4Sc股份公司 新颖的杂环NF-κB抑制剂
GB0619325D0 (en) 2006-09-30 2006-11-08 Univ Strathclyde New compounds
JP2011525535A (ja) * 2008-06-24 2011-09-22 武田薬品工業株式会社 ＰＩ３Ｋ／ｍＴＯＲ阻害剤
US9499790B2 (en) 2010-08-26 2016-11-22 Kyoto University Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells
AP2014007595A0 (en) * 2011-09-30 2014-04-30 Kineta Inc Anti-viral compounds
EP2808383B1 (en) 2012-01-27 2018-07-25 Kyoto University Method for inducing cardiac differentiation of pluripotent stem cell
EP2966166B1 (en) 2013-03-08 2019-04-03 Kyoto University Promoter of differentiation of pluripotent stem cell into myocardium, which comprises egf receptor inhibitor
WO2015037706A1 (ja) * 2013-09-13 2015-03-19 国立大学法人京都大学 多能性幹細胞の心筋分化を促進する化合物
US10233426B2 (en) 2014-05-30 2019-03-19 Kyoto University Method for inducing cardiac differentiation of pluripotent stem cell with low-molecular compounds
CN109776486A (zh) * 2019-02-26 2019-05-21 武汉松石科技股份有限公司 一种硫酸亚丙酯的制备方法
CN110590735B (zh) * 2019-09-30 2021-07-23 江苏国泰超威新材料有限公司 一种环状硫酸酯的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61225168A (ja) * 1985-03-30 1986-10-06 Nippon Tokushu Noyaku Seizo Kk 新規ベンズアミド、その製法及び殺虫剤
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
GB8611606D0 (en) * 1986-05-13 1986-06-18 Fbc Ltd Fungicides

Also Published As

Publication number Publication date
KR910006864B1 (ko) 1991-09-09
DK249389D0 (da) 1989-05-23
AU601905B2 (en) 1990-09-20
DD283815A5 (de) 1990-10-24
IL90337A0 (en) 1989-12-15
DE68902358T2 (de) 1992-12-10
YU105989A (en) 1990-08-31
SU1681728A3 (ru) 1991-09-30
CN1023700C (zh) 1994-02-09
FI892498A (fi) 1989-11-25
ES2043012T3 (es) 1993-12-16
ATE79114T1 (de) 1992-08-15
MY106035A (en) 1995-03-31
JPH0678331B2 (ja) 1994-10-05
NO172389B (no) 1993-04-05
PL279613A1 (en) 1989-11-27
IE891667L (en) 1989-11-24
MX173140B (es) 1994-02-02
NO892059D0 (no) 1989-05-23
PL154875B1 (en) 1991-09-30
FI892498A0 (fi) 1989-05-23
AU3509889A (en) 1989-11-30
PT90622B (pt) 1994-10-31
NZ229234A (en) 1990-09-26
DE68902358D1 (de) 1992-09-10
JPH0217181A (ja) 1990-01-22
PT90622A (pt) 1989-11-30
HU202507B (en) 1991-03-28
GR3005844T3 (xx) 1993-06-07
CA1328871C (en) 1994-04-26
HUT51606A (en) 1990-05-28
NO172389C (no) 1993-07-14
NO892059L (no) 1989-11-27
KR890017248A (ko) 1989-12-15
EP0343893A1 (en) 1989-11-29
CN1037898A (zh) 1989-12-13
EP0343893B1 (en) 1992-08-05
YU47019B (sh) 1994-11-15
MX16158A (es) 1993-06-01
DK249389A (da) 1989-11-27

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