IE62974B1 - Method for determination of a polyvalent substance using an immunoaggregate - Google Patents
Method for determination of a polyvalent substance using an immunoaggregateInfo
- Publication number
- IE62974B1 IE62974B1 IE68389A IE68389A IE62974B1 IE 62974 B1 IE62974 B1 IE 62974B1 IE 68389 A IE68389 A IE 68389A IE 68389 A IE68389 A IE 68389A IE 62974 B1 IE62974 B1 IE 62974B1
- Authority
- IE
- Ireland
- Prior art keywords
- specific
- igg
- aggregates
- reactants
- mab33
- Prior art date
Links
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- 238000011533 pre-incubation Methods 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 229940097325 prolactin Drugs 0.000 description 1
- 210000002307 prostate Anatomy 0.000 description 1
- 239000000941 radioactive substance Substances 0.000 description 1
- 238000003127 radioimmunoassay Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000010405 reoxidation reaction Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- HELHAJAZNSDZJO-OLXYHTOASA-L sodium L-tartrate Chemical compound [Na+].[Na+].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O HELHAJAZNSDZJO-OLXYHTOASA-L 0.000 description 1
- 239000001433 sodium tartrate Substances 0.000 description 1
- 229960002167 sodium tartrate Drugs 0.000 description 1
- 235000011004 sodium tartrates Nutrition 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 229940043517 specific immunoglobulins Drugs 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/6857—Antibody fragments
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/824—Immunological separation techniques
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/825—Pretreatment for removal of interfering factors from sample
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Electrotherapy Devices (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/164,054 US4914040A (en) | 1988-03-03 | 1988-03-03 | Reagent and method for determination of a polyvalent substance using an immunoaggregate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE890683L IE890683L (en) | 1989-09-03 |
| IE62974B1 true IE62974B1 (en) | 1995-03-08 |
Family
ID=22592781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE68389A IE62974B1 (en) | 1988-03-03 | 1989-03-02 | Method for determination of a polyvalent substance using an immunoaggregate |
Country Status (18)
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3730059A1 (de) * | 1987-09-08 | 1989-03-30 | Behringwerke Ag | Verfahren zur bestimmung von "loeslichem" fibrin |
| US5141853A (en) * | 1988-07-22 | 1992-08-25 | Abbott Laboratories | Determination of ammonia levels in a sample |
| DE3829245A1 (de) * | 1988-08-29 | 1990-03-01 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung einer spezifisch bindefaehigen substanz |
| AU6710790A (en) * | 1989-10-24 | 1991-05-31 | E.I. Du Pont De Nemours And Company | Use of polymerized immunoglobulin to reduce the incidence of false-positive responses in immunoassays |
| DE4020204A1 (de) * | 1990-06-25 | 1992-01-02 | Boehringer Mannheim Gmbh | Durchfuehrung eines homogenen immunoassays nach dem agglutinationsprinzip |
| US6274325B1 (en) | 1990-06-25 | 2001-08-14 | Boehringer Mannheim Gmbh | Method for carrying out a homogeneous-immunoassay based on agglutination |
| JPH04350559A (ja) * | 1991-05-28 | 1992-12-04 | Dai Ichi Pure Chem Co Ltd | 特異抗体の測定法 |
| WO1993003366A1 (en) * | 1991-07-26 | 1993-02-18 | E.I. Du Pont De Nemours And Company | Method for eliminating erroneous results in an immunoassay |
| US5460944A (en) * | 1991-10-28 | 1995-10-24 | Boehringer Mannheim Gmbh | Storable protein solution |
| DE4202923A1 (de) * | 1992-02-01 | 1993-08-05 | Behringwerke Ag | Verfahren zur bestimmung von antigenen oder antikoerpern in gegenwart eines immunkomplexes |
| IL102495A (en) * | 1992-07-14 | 1998-06-15 | Patchornik Avraham | Universal standard reagents, method of preparing same and use thereof |
| IL106887A (en) * | 1993-09-02 | 1997-02-18 | Yissum Res Dev Co | Pharmaceutical and diagnostic compositions and a method for drug targeting |
| GB9403215D0 (en) * | 1994-02-19 | 1994-04-13 | Kodak Ltd | Chemical modification of antibodies and antigens |
| DE4407423A1 (de) * | 1994-03-05 | 1995-09-07 | Boehringer Mannheim Gmbh | Entstörmittel zum Einsatz bei Immunoassays |
| CA2184386C (en) * | 1994-03-05 | 2005-10-18 | Rosemarie Kientsch-Engel | Interference eliminating agent for application in immunoassays |
| DE4439452A1 (de) * | 1994-11-04 | 1996-05-09 | Boehringer Mannheim Gmbh | Antikörperklassenspezifisches Entstörungsreagenz |
| DE19621133A1 (de) * | 1996-05-24 | 1997-11-27 | Boehringer Mannheim Gmbh | Bestimmungsverfahren mit oligomerisierten Rezeptoren |
| DE19731465A1 (de) | 1997-07-22 | 1999-01-28 | Boehringer Mannheim Gmbh | Verwendung von Kontrollflächen zur Detektion von Störproben in einem Nachweisverfahren |
| ATE225511T1 (de) * | 1997-12-11 | 2002-10-15 | Roche Diagnostics Gmbh | Entstörung von diagnostischen verfahren durch peptide aus d-aminosäuren |
| DE19828466A1 (de) | 1998-06-26 | 1999-12-30 | Roche Diagnostics Gmbh | Entstörung von Immunoassays durch Substanzen, die aus den Framework-Regionen von Antikörpern abgeleitet sind |
| US6406858B1 (en) * | 1998-11-27 | 2002-06-18 | Bayer Corporation | System for the reduction of interferences in immunoassays |
| JP2004510161A (ja) * | 2000-09-25 | 2004-04-02 | アボット・ラボラトリーズ | 高分子ポリカチオンを用いることにより、特異的結合アッセイにおける血清または血漿含有アッセイ試料の干渉を減少させるための方法及びキット |
| DE10059720A1 (de) | 2000-11-30 | 2002-06-06 | Roche Diagnostics Gmbh | Verwendung intramolekular kovalent vernetzter Proteine als Bindepartner in Immunoassays |
| DE10064827A1 (de) | 2000-12-22 | 2002-06-27 | Dade Behring Marburg Gmbh | Nachweisverfahren |
| US20040091952A1 (en) * | 2002-07-25 | 2004-05-13 | Sysmex Corporation | Reagent kit for detecting lupus anticoagulant |
| US20040018556A1 (en) * | 2002-07-29 | 2004-01-29 | Cantor Thomas L. | Reagent and method for determination of a substance using an immunoaggregator |
| DE602004016906D1 (de) * | 2003-03-28 | 2008-11-20 | Sysmex Corp | Reagenz zum Nachweis von anti-Phospholipid Antikörper |
| JP2007526993A (ja) * | 2003-07-08 | 2007-09-20 | インバーネス・メデイカル・スウイツツアーランド・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | 粒子凝集検出方法および装置 |
| US20050112586A1 (en) * | 2003-11-24 | 2005-05-26 | Roland Janzen | Method and composition for stabilizing liquid reagents |
| EP1562047B1 (en) * | 2004-02-06 | 2008-05-14 | Sysmex Corporation | Reagent kit for detecting lupus anticoagulant |
| CN1969189B (zh) * | 2004-06-14 | 2012-03-21 | 协和梅迪克斯株式会社 | 非特异性反应被抑制的可溶性白介素-2受体免疫学测定方法和试剂 |
| US20060105402A1 (en) * | 2004-11-15 | 2006-05-18 | Gennady Rott | Blood type method system and device |
| US7172906B2 (en) * | 2004-11-16 | 2007-02-06 | Dade Behring Inc. | Reduction of non-specific binding in assays |
| CA2697656C (en) * | 2007-08-23 | 2017-10-03 | Mitsubishi Chemical Medience Corporation | Non-specific reaction inhibitor |
| US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
| WO2019207115A1 (en) * | 2018-04-26 | 2019-10-31 | Statens Serum Institut | Improved immunoassays |
| CN109342743B (zh) * | 2018-12-05 | 2022-02-18 | 菲鹏生物股份有限公司 | 一种能够与类风湿因子高效结合的变性IgG的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0083869B1 (en) * | 1982-01-05 | 1985-10-16 | International Institute Of Cellular And Molecular Pathology (Icp) | Method of immunoassay |
| DE3206729A1 (de) * | 1982-02-25 | 1983-09-01 | Behringwerke Ag, 3550 Marburg | Immunologisches agglutinationsverfahren |
| DE3225027A1 (de) * | 1982-07-05 | 1984-01-05 | Boehringer Mannheim Gmbh, 6800 Mannheim | Immunchemisches messverfahren |
| US4659678A (en) * | 1982-09-29 | 1987-04-21 | Serono Diagnostics Limited | Immunoassay of antigens |
| US4474892A (en) * | 1983-02-16 | 1984-10-02 | Board Of Trustees Of The Leland Stanford Junior University | Two-site immunoassays using monoclonal antibodies of different classes or subclasses and test kits for performing same |
| US4582810A (en) * | 1983-09-30 | 1986-04-15 | Becton, Dickinson And Company | Immuno-agglutination particle suspensions |
| JPS60256057A (ja) * | 1984-06-01 | 1985-12-17 | Dai Ichi Pure Chem Co Ltd | 免疫学的測定法 |
| JPS6165162A (ja) * | 1984-09-05 | 1986-04-03 | Chemo Sero Therapeut Res Inst | モノクロ−ナル抗体を用いた免疫学的測定方法における非特異反応吸収剤 |
| JPH0799372B2 (ja) * | 1985-07-13 | 1995-10-25 | 富士レビオ株式会社 | 逆受身凝集反応用非特異反応吸収剤 |
-
1988
- 1988-03-03 US US07/164,054 patent/US4914040A/en not_active Expired - Lifetime
-
1989
- 1989-02-23 DE DE3905505A patent/DE3905505A1/de not_active Withdrawn
- 1989-02-27 ES ES89103388T patent/ES2045216T3/es not_active Expired - Lifetime
- 1989-02-27 AT AT89103388T patent/ATE82072T1/de not_active IP Right Cessation
- 1989-02-27 EP EP89103388A patent/EP0331068B1/de not_active Expired - Lifetime
- 1989-02-27 DE DE8989103388T patent/DE58902586D1/de not_active Expired - Lifetime
- 1989-02-28 DD DD89326088A patent/DD280396A5/de not_active IP Right Cessation
- 1989-02-28 DK DK198900966A patent/DK175429B1/da not_active IP Right Cessation
- 1989-03-01 AU AU30908/89A patent/AU616484B2/en not_active Expired
- 1989-03-01 ZA ZA891568A patent/ZA891568B/xx unknown
- 1989-03-02 RU SU894613606A patent/RU2032906C1/ru active
- 1989-03-02 HU HU891015A patent/HU212322B/hu unknown
- 1989-03-02 IE IE68389A patent/IE62974B1/en not_active IP Right Cessation
- 1989-03-02 FI FI891012A patent/FI92879C/fi not_active IP Right Cessation
- 1989-03-02 PT PT89889A patent/PT89889B/pt not_active IP Right Cessation
- 1989-03-03 JP JP1050230A patent/JPH0823560B2/ja not_active Expired - Lifetime
- 1989-03-03 CA CA000592675A patent/CA1340572C/en not_active Expired - Lifetime
-
1993
- 1993-02-05 GR GR920402739T patent/GR3006991T3/el unknown
- 1993-06-02 LV LVP-93-465A patent/LV10538B/lv unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI92879B (fi) | 1994-09-30 |
| DD280396A5 (de) | 1990-07-04 |
| FI891012A0 (fi) | 1989-03-02 |
| ZA891568B (en) | 1989-11-29 |
| US4914040A (en) | 1990-04-03 |
| DE3905505A1 (de) | 1989-09-14 |
| JPH01254869A (ja) | 1989-10-11 |
| JPH0823560B2 (ja) | 1996-03-06 |
| DK96689D0 (da) | 1989-02-28 |
| AU616484B2 (en) | 1991-10-31 |
| RU2032906C1 (ru) | 1995-04-10 |
| IE890683L (en) | 1989-09-03 |
| FI92879C (fi) | 1995-01-10 |
| HUT50988A (en) | 1990-03-28 |
| EP0331068A1 (de) | 1989-09-06 |
| FI891012L (fi) | 1989-09-04 |
| PT89889A (pt) | 1989-11-10 |
| AU3090889A (en) | 1989-09-07 |
| DK175429B1 (da) | 2004-10-18 |
| GR3006991T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-06-30 |
| DE58902586D1 (de) | 1992-12-10 |
| HU212322B (en) | 1996-05-28 |
| ATE82072T1 (de) | 1992-11-15 |
| LV10538B (en) | 1995-12-20 |
| DK96689A (da) | 1989-09-04 |
| CA1340572C (en) | 1999-06-01 |
| EP0331068B1 (de) | 1992-11-04 |
| LV10538A (lv) | 1995-02-20 |
| ES2045216T3 (es) | 1994-01-16 |
| PT89889B (pt) | 1994-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK9A | Patent expired |