ID29517A - Prosedur pemurnian insulin secara kromatografis - Google Patents

Prosedur pemurnian insulin secara kromatografis

Info

Publication number
ID29517A
ID29517A IDW20010441A ID20010441A ID29517A ID 29517 A ID29517 A ID 29517A ID W20010441 A IDW20010441 A ID W20010441A ID 20010441 A ID20010441 A ID 20010441A ID 29517 A ID29517 A ID 29517A
Authority
ID
Indonesia
Prior art keywords
purification
insulin
procedure
chromatographic
chromatographic purification
Prior art date
Application number
IDW20010441A
Other languages
English (en)
Inventor
Werner Dr Siever
Richard Dr Bicker
Jorg Von Dr Eysmondt
Frank Dr Richard
Dieter Desch
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of ID29517A publication Critical patent/ID29517A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
IDW20010441A 1998-08-24 1999-08-11 Prosedur pemurnian insulin secara kromatografis ID29517A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19838097A DE19838097A1 (de) 1998-08-24 1998-08-24 Verfahren zur chromatographischen Reinigung von Insulinen

Publications (1)

Publication Number Publication Date
ID29517A true ID29517A (id) 2001-09-06

Family

ID=7878335

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20010441A ID29517A (id) 1998-08-24 1999-08-11 Prosedur pemurnian insulin secara kromatografis

Country Status (23)

Country Link
US (1) US6710167B1 (id)
EP (1) EP1107988B1 (id)
JP (1) JP2002523732A (id)
KR (1) KR100703578B1 (id)
CN (1) CN1198843C (id)
AT (1) ATE380827T1 (id)
AU (1) AU756105B2 (id)
BR (1) BR9913092A (id)
CA (1) CA2341355C (id)
CY (1) CY1107877T1 (id)
CZ (1) CZ300604B6 (id)
DE (2) DE19838097A1 (id)
DK (1) DK1107988T3 (id)
ES (1) ES2296407T3 (id)
HK (1) HK1039130B (id)
HU (1) HU227753B1 (id)
ID (1) ID29517A (id)
PL (1) PL201880B1 (id)
PT (1) PT1107988E (id)
RU (1) RU2222546C2 (id)
TR (1) TR200100634T2 (id)
WO (1) WO2000011030A2 (id)
ZA (1) ZA200101096B (id)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19838097A1 (de) * 1998-08-24 2000-03-02 Hoechst Marion Roussel De Gmbh Verfahren zur chromatographischen Reinigung von Insulinen
AU2003278550A1 (en) * 2002-12-05 2004-06-23 Edupuganti B. Raju Process for the extraction and isolation of insulin from recombinant sources
US6921703B2 (en) * 2003-05-13 2005-07-26 Texas Instruments Incorporated System and method for mitigating oxide growth in a gate dielectric
EP1589045B1 (en) * 2004-04-20 2007-03-14 Rohm And Haas Company Polymeric adsorbent, and method of preparation and use
WO2005115303A1 (en) * 2004-05-24 2005-12-08 Wockhardt Limited Purification of insulin-like material by reverse phase chromatography
DE102004051807B4 (de) * 2004-10-25 2008-10-09 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verwendung von hydrophobiertem Kieselgel als selektives Sorbens zur Entfernung von organischen Siliziumverbindungen
CN100368804C (zh) * 2006-01-24 2008-02-13 李振国 测定注射剂中高分子量物质含量的方法
JP2012532862A (ja) * 2009-07-09 2012-12-20 バイオコン リミティド 調製用非線形勾配に基づくクロマトグラフィー法及びその精製産物
EP2659501B1 (en) * 2010-12-28 2017-09-06 Quest Diagnostics Investments Incorporated Quantitation of insulin by mass spectrometry
RU2453331C1 (ru) * 2011-06-29 2012-06-20 Общество с ограниченной ответственностью "Завод Медсинтез" Способ получения высокоочищенного кристаллического инсулина любого происхождения
PL2748181T3 (pl) 2011-09-30 2016-08-31 Ge Healthcare Bioprocess R&D Ab Sposób oczyszczania rozszczepionej proinsuliny
WO2014099577A1 (en) 2012-12-17 2014-06-26 Merck Sharp & Dohme Corp. Process for purifying insulin and analogues thereof
CN103275210B (zh) * 2013-06-25 2015-02-25 珠海联邦制药股份有限公司 脂肪酸单酰化胰岛素的色谱纯化方法
WO2015138548A1 (en) 2014-03-14 2015-09-17 Merck Sharp & Dohme Corp. Purifying insulin using cation exchange and reverse phase chromatography in the presence of an organic modifier and elevated temperature
US10155799B2 (en) 2014-07-21 2018-12-18 Merck Sharp & Dohme Corp. Chromatography process for purification of insulin and insulin analogs
CN105111305B (zh) * 2015-10-10 2018-12-14 山东阿华生物药业有限公司 酰化胰岛素的色谱纯化方法
RU2736358C2 (ru) * 2015-12-09 2020-11-16 Общество С Ограниченной Ответственностью "Синбио" Способ очистки полисиалированного инсулина человека

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1285024A (en) * 1968-08-09 1972-08-09 Novo Terapeutisk Labor As Process of purifying insulin
NZ199391A (en) 1981-01-02 1985-12-13 Genentech Inc Chimeric polypeptides comprising a proinsulin sequence,and preparation by recombinant dna technique;production of human insulin
US4616078A (en) * 1985-04-08 1986-10-07 Eli Lilly And Company Process for purifying proinsulin-like materials
DE3837825A1 (de) 1988-11-08 1990-05-10 Hoechst Ag Neue insulinderivate, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
DE4028120C2 (de) 1990-09-05 1996-09-19 Hoechst Ag Verfahren zur Reinigung von Insulin und/oder Insulinderivaten
DE59208181D1 (de) * 1991-12-18 1997-04-17 Hoechst Ag Verfahren zur Gewinnung von insulinhaltigen Lösungen
DK0600372T3 (da) 1992-12-02 1997-08-11 Hoechst Ag Fremgangsmåde til fremstilling af proinsulin med korrekt forbundne cystinbroer.
DE4405179A1 (de) 1994-02-18 1995-08-24 Hoechst Ag Verfahren zur Gewinnung von Insulin mit korrekt verbundenen Cystinbrücken
DK0821006T3 (da) 1996-07-26 2004-08-16 Aventis Pharma Gmbh Insulinderivater med öget zinkbinding
DE19652713C2 (de) * 1996-12-18 2001-11-22 Aventis Pharma Gmbh Verfahren zur Reinigung von Insulin und Insulinderivaten durch Chromatographie an stark saurem Kationenaustauscher
DE19838097A1 (de) * 1998-08-24 2000-03-02 Hoechst Marion Roussel De Gmbh Verfahren zur chromatographischen Reinigung von Insulinen

Also Published As

Publication number Publication date
HK1039130A1 (en) 2002-04-12
EP1107988A2 (de) 2001-06-20
ATE380827T1 (de) 2007-12-15
CA2341355A1 (en) 2000-03-02
HUP0103325A2 (hu) 2001-12-28
DE59914580D1 (de) 2008-01-24
CY1107877T1 (el) 2013-06-19
JP2002523732A (ja) 2002-07-30
CZ2001646A3 (cs) 2001-09-12
AU5733199A (en) 2000-03-14
RU2222546C2 (ru) 2004-01-27
HU227753B1 (en) 2012-02-28
TR200100634T2 (tr) 2001-07-23
DE19838097A1 (de) 2000-03-02
CZ300604B6 (cs) 2009-06-24
PL346865A1 (en) 2002-03-11
DK1107988T3 (da) 2008-04-21
KR100703578B1 (ko) 2007-04-05
CN1198843C (zh) 2005-04-27
US6710167B1 (en) 2004-03-23
ZA200101096B (en) 2002-06-26
PL201880B1 (pl) 2009-05-29
EP1107988B1 (de) 2007-12-12
AU756105B2 (en) 2003-01-02
PT1107988E (pt) 2008-01-16
WO2000011030A2 (de) 2000-03-02
ES2296407T3 (es) 2008-04-16
HUP0103325A3 (en) 2003-09-29
HK1039130B (zh) 2006-05-12
CA2341355C (en) 2009-04-07
WO2000011030A3 (de) 2000-06-02
BR9913092A (pt) 2001-10-30
KR20010072914A (ko) 2001-07-31
CN1313866A (zh) 2001-09-19

Similar Documents

Publication Publication Date Title
ID29517A (id) Prosedur pemurnian insulin secara kromatografis
EP1081492A4 (en) FILLING FOR CHROMATOGRAPHY HAVING A NEW CHARACTERISTIC AND METHOD FOR ISOLATING A SUBSTANCE USING THE SAME
GB2437442A (en) Improved process for purification of 6 acetyl 4,1',6' trichlorogalactosucrose and 4,1',6' trichlorogalactosucrose by chromatography on silanized silica gel
PT934325E (pt) Trisanidridos biciclicos de tetrafosfonato
EA199800579A1 (ru) Новые производные 5-амино-3-циано-4-этилсульфинил-1-фенилпиразола и их применение в качестве пестицидов
DK0746398T3 (da) Antistofrensning
BR9807734A (pt) Composto para imunodiagnose de câncer de próstata e métodos para o uso dos memos
TR200001012T2 (tr) Yeni ariloksi-alkil-dialkilaminler.
EP0903578A3 (en) A composition and column used in HPLC, a method for preparing the composition, and a method for separating different chemicals in a sample
FI914150A (fi) Menetelmä insuliinien puhdistamiseksi kromatografisesti
WO2002018929A3 (en) Chromatography and other adsorptions using modified carbon adsorbents
TR200200353T2 (tr) Torsemid Polimorfları
ATE244728T1 (de) Antibiotisch wirksame, alkylierte hexapeptide
BR9102321A (pt) Composicao,metodo de estabilizar um material organico,composto
EA199900235A1 (ru) Аморфные бензотиофены, способы получения и способы применения
RU95112519A (ru) (3,4-ди-фторфенокси)метил оксиран и способ его получения
ES2100051T3 (es) Sintesis de bloques dimeros y su uso en el ensamblaje de oligonucleotidos.
BR9710386A (pt) Composto processo de prepara-Æo do composto e processo de transforma-Æo do composto
PT920447E (pt) Processo para a purificacao de ciclosporinas
DK1019521T3 (da) Fremgangsmåde til biotransformation af colchiconforbindelser til de tilsvarende 3-glycosylderivater
ATE376007T1 (de) Polyvinylether
AU4734097A (en) Method for discovering novel anthelmintic compounds
EA200000705A1 (ru) Промежуточные соединения и способ синтеза 17-замещенных 16.бета.-арилокси 4-азастероидов
EA199800274A1 (ru) Способ получения бензилзамещенных производных роданина
MX9605277A (es) Procedimiento para obtener carboxilatos croman.