ID18685A - Senyawa trisiklik tersubstitusi - Google Patents

Senyawa trisiklik tersubstitusi

Info

Publication number
ID18685A
ID18685A IDP973534A ID973534A ID18685A ID 18685 A ID18685 A ID 18685A ID P973534 A IDP973534 A ID P973534A ID 973534 A ID973534 A ID 973534A ID 18685 A ID18685 A ID 18685A
Authority
ID
Indonesia
Prior art keywords
trisiclic
substituted
compounds
trisiclic compounds
substituted trisiclic
Prior art date
Application number
IDP973534A
Other languages
English (en)
Indonesian (id)
Inventor
Nicholas James Bach
Robert Delane Dillard
Susan Elizabeth Draheim
John Michael Junior Morin
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ID18685A publication Critical patent/ID18685A/id

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572Five-membered rings
    • C07F9/5728Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Fats And Perfumes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Steroid Compounds (AREA)
IDP973534A 1996-10-30 1997-10-27 Senyawa trisiklik tersubstitusi ID18685A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2984996P 1996-10-30 1996-10-30

Publications (1)

Publication Number Publication Date
ID18685A true ID18685A (id) 1998-04-30

Family

ID=21851210

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP973534A ID18685A (id) 1996-10-30 1997-10-27 Senyawa trisiklik tersubstitusi

Country Status (26)

Country Link
EP (1) EP0839806B1 (zh)
JP (1) JP2001503055A (zh)
KR (1) KR20000049210A (zh)
CN (1) CN1233176A (zh)
AR (1) AR010050A1 (zh)
AT (1) ATE244703T1 (zh)
AU (1) AU734096B2 (zh)
BR (1) BR9713261A (zh)
CA (1) CA2269203A1 (zh)
CO (1) CO4920250A1 (zh)
CZ (1) CZ136899A3 (zh)
DE (1) DE69723393T2 (zh)
DK (1) DK0839806T3 (zh)
EA (1) EA003992B1 (zh)
ES (1) ES2202560T3 (zh)
ID (1) ID18685A (zh)
IL (1) IL129481A0 (zh)
NO (1) NO314899B1 (zh)
NZ (1) NZ335246A (zh)
PE (1) PE10999A1 (zh)
PL (1) PL332896A1 (zh)
PT (1) PT839806E (zh)
TR (1) TR199900956T2 (zh)
TW (1) TW513428B (zh)
WO (1) WO1998018464A1 (zh)
YU (1) YU19299A (zh)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU9123198A (en) * 1997-08-28 1999-03-16 Eli Lilly And Company Method for treatment of non-rheumatoid athritis
KR20010042307A (ko) 1998-03-31 2001-05-25 시오노 요시히코 피롤로[1,2-a]피라진 sPLA2 억제제
ID23219A (id) * 1998-04-17 2000-03-30 Lilly Co Eli Trisiklik tersubstitusi
DZ2769A1 (fr) * 1998-04-17 2003-12-01 Lilly Co Eli Composés tricycliques substitués.
WO1999057100A1 (en) 1998-05-01 1999-11-11 Eli Lilly And Company Spla2 inhibitor compounds for treatment of disease
CA2332528A1 (en) 1998-05-21 1999-11-25 Shionogi & Co., Ltd. Pyrrolo[1,2-b]pyridazine spla2 inhibitory
DE69931963D1 (de) * 1998-10-14 2006-07-27 Shionogi & Co Spla2-inhibitoren zur behandlung von ischämischen reperfusionsschäden
CA2356162A1 (en) * 1998-12-22 2000-06-29 Eli Lilly And Company Substituted tricyclics
WO2001005789A1 (fr) 1999-07-19 2001-01-25 Shionogi & Co., Ltd. Composes tricycliques a action inhibitrice a l'encontre de spla¿2?
AU6023200A (en) 1999-08-02 2001-02-19 Shionogi & Co., Ltd. Tricyclic compounds having spla2-inhibitory activities
WO2001014378A1 (fr) 1999-08-23 2001-03-01 Shionogi & Co., Ltd. DERIVES DE PYRROLOTRIAZINE A ACTIVITES INHIBANT sPLA¿2?
MY125942A (en) 1999-09-07 2006-09-29 Upjohn Co Aminoalkoxy carbazoles for the treatment of cns diseases
US6756376B1 (en) 1999-11-15 2004-06-29 Shionogi & Co., Ltd. Tricyclic azaindolizine derivatives having an sPLA2-inhibitory activities
JP2003519198A (ja) * 2000-01-06 2003-06-17 イーライ・リリー・アンド・カンパニー 炎症性疾患および呼吸器疾患の処置のための併用療法
US6967200B2 (en) 2000-06-29 2005-11-22 Shionogi & Co., Ltd. Remedies for cirrhosis
JPWO2002000621A1 (ja) 2000-06-29 2004-04-22 塩野義製薬株式会社 X型sPLA2阻害作用を有する化合物
EP1345898A2 (en) 2000-12-18 2003-09-24 Eli Lilly And Company Teracyclic carbazole derivates and their use as spla2 inhibitors
TWI314457B (zh) * 2001-03-19 2009-09-11 Shionogi & Co
AUPS282602A0 (en) 2002-06-07 2002-06-27 Garvan Institute Of Medical Research Method of inhibiting cell proliferation
SI1852433T1 (sl) 2004-10-29 2012-06-29 Zeria Pharm Co Ltd Derivat karbazola, njegov solvat ali njegova farmacevtsko sprejemljiva sol
EP3307323B1 (en) 2015-06-15 2022-07-13 Raziel Therapeutics Ltd. Carbazole derivatives for the treatment of fibrotic diseases and related symptoms, and conditions thereof
CN112409493B (zh) * 2020-08-12 2022-09-30 浙江工业大学 一种重组融合酶及其在乙醛酸甲酯合成中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3479391A (en) * 1966-10-03 1969-11-18 Squibb & Sons Inc Delta**3,14-17alpha-hydroxy-norprogesterone and esters
US3939177A (en) * 1972-11-22 1976-02-17 Sterling Drug Inc. 4-Aminomethyl-9-benzyl-1,2,3,4-tetrahydrocarbazoles
US3979391A (en) * 1972-11-22 1976-09-07 Sterling Drug Inc. 1,2,3,4-Tetrahydrocarbazoles
US5420289A (en) * 1989-10-27 1995-05-30 American Home Products Corporation Substituted indole-, indene-, pyranoindole- and tetrahydrocarbazole-alkanoic acid derivatives as inhibitors of PLA2 and lipoxygenase
IL109309A (en) * 1993-04-16 2000-06-29 Lilly Co Eli 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them
IL109311A0 (en) * 1993-04-16 1994-07-31 Lilly Co Eli 1H-indole-3-acetamide sPla2 inhibitors

Also Published As

Publication number Publication date
NZ335246A (en) 2001-09-28
NO991831D0 (no) 1999-04-16
AR010050A1 (es) 2000-05-17
CO4920250A1 (es) 2000-05-29
PL332896A1 (en) 1999-10-25
PE10999A1 (es) 1999-02-10
PT839806E (pt) 2003-11-28
WO1998018464A1 (en) 1998-05-07
BR9713261A (pt) 2000-03-28
EP0839806B1 (en) 2003-07-09
NO991831L (no) 1999-06-21
EP0839806A1 (en) 1998-05-06
EA199900305A1 (ru) 1999-12-29
KR20000049210A (ko) 2000-07-25
NO314899B1 (no) 2003-06-10
ATE244703T1 (de) 2003-07-15
AU5149498A (en) 1998-05-22
AU734096B2 (en) 2001-06-07
YU19299A (sh) 2000-03-21
DK0839806T3 (da) 2003-10-27
CA2269203A1 (en) 1998-05-07
EA003992B1 (ru) 2003-12-25
JP2001503055A (ja) 2001-03-06
DE69723393D1 (de) 2003-08-14
DE69723393T2 (de) 2004-06-09
IL129481A0 (en) 2000-02-29
ES2202560T3 (es) 2004-04-01
CZ136899A3 (cs) 1999-09-15
TW513428B (en) 2002-12-11
CN1233176A (zh) 1999-10-27
TR199900956T2 (xx) 1999-07-21

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