ATE244703T1 - Substituierte tricyclische verbindungen - Google Patents
Substituierte tricyclische verbindungenInfo
- Publication number
- ATE244703T1 ATE244703T1 AT97308645T AT97308645T ATE244703T1 AT E244703 T1 ATE244703 T1 AT E244703T1 AT 97308645 T AT97308645 T AT 97308645T AT 97308645 T AT97308645 T AT 97308645T AT E244703 T1 ATE244703 T1 AT E244703T1
- Authority
- AT
- Austria
- Prior art keywords
- tricyclic compounds
- substituted tricyclic
- substituted
- compounds
- tricyclic
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- C07F9/5728—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyridine Compounds (AREA)
- Fats And Perfumes (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2984996P | 1996-10-30 | 1996-10-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE244703T1 true ATE244703T1 (de) | 2003-07-15 |
Family
ID=21851210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97308645T ATE244703T1 (de) | 1996-10-30 | 1997-10-29 | Substituierte tricyclische verbindungen |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP0839806B1 (de) |
| JP (1) | JP2001503055A (de) |
| KR (1) | KR20000049210A (de) |
| CN (1) | CN1233176A (de) |
| AR (1) | AR010050A1 (de) |
| AT (1) | ATE244703T1 (de) |
| AU (1) | AU734096B2 (de) |
| BR (1) | BR9713261A (de) |
| CA (1) | CA2269203A1 (de) |
| CO (1) | CO4920250A1 (de) |
| CZ (1) | CZ136899A3 (de) |
| DE (1) | DE69723393T2 (de) |
| DK (1) | DK0839806T3 (de) |
| EA (1) | EA003992B1 (de) |
| ES (1) | ES2202560T3 (de) |
| ID (1) | ID18685A (de) |
| IL (1) | IL129481A0 (de) |
| NO (1) | NO314899B1 (de) |
| NZ (1) | NZ335246A (de) |
| PE (1) | PE10999A1 (de) |
| PL (1) | PL332896A1 (de) |
| PT (1) | PT839806E (de) |
| TR (1) | TR199900956T2 (de) |
| TW (1) | TW513428B (de) |
| WO (1) | WO1998018464A1 (de) |
| YU (1) | YU19299A (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1011670A4 (de) * | 1997-08-28 | 2004-10-27 | Lilly Co Eli | Verfahren zur behandlung von nicht-rheumatischer arthritis |
| AU3054399A (en) | 1998-03-31 | 1999-10-25 | Shionogi & Co., Ltd. | Pyrrolo(1,2-a)pyrazine sPLA2 inhibitor |
| DZ2769A1 (fr) * | 1998-04-17 | 2003-12-01 | Lilly Co Eli | Composés tricycliques substitués. |
| ID23219A (id) * | 1998-04-17 | 2000-03-30 | Lilly Co Eli | Trisiklik tersubstitusi |
| US6340699B1 (en) | 1998-05-01 | 2002-01-22 | Eli Lilly And Company | SPLA2 inhibitor compounds for treatment of disease |
| CA2332528A1 (en) | 1998-05-21 | 1999-11-25 | Shionogi & Co., Ltd. | Pyrrolo[1,2-b]pyridazine spla2 inhibitory |
| CA2346334A1 (en) * | 1998-10-14 | 2000-04-20 | Shionogi & Co., Ltd. | Composition for treating or preventing ischemia reperfusion injury |
| AU1928800A (en) * | 1998-12-22 | 2000-07-12 | Eli Lilly And Company | Substituted tricyclics |
| JP4636521B2 (ja) | 1999-07-19 | 2011-02-23 | 塩野義製薬株式会社 | ｓＰＬＡ２阻害作用を有する三環系化合物 |
| JP4636522B2 (ja) | 1999-08-02 | 2011-02-23 | 塩野義製薬株式会社 | ｓＰＬＡ２阻害作用を有する三環式化合物 |
| WO2001014378A1 (fr) | 1999-08-23 | 2001-03-01 | Shionogi & Co., Ltd. | DERIVES DE PYRROLOTRIAZINE A ACTIVITES INHIBANT sPLA¿2? |
| MY125942A (en) | 1999-09-07 | 2006-09-29 | Upjohn Co | Aminoalkoxy carbazoles for the treatment of cns diseases |
| AU1304801A (en) | 1999-11-15 | 2001-05-30 | Shionogi & Co., Ltd. | Tricyclic azaindolizine derivatives having an SPLA2- inhibiting effect |
| WO2001049323A1 (en) * | 2000-01-06 | 2001-07-12 | Eli Lilly And Company | Combination therapy for the treatment of inflammatory and respiratory diseases |
| JPWO2002000621A1 (ja) | 2000-06-29 | 2004-04-22 | 塩野義製薬株式会社 | Ｘ型ｓＰＬＡ２阻害作用を有する化合物 |
| AU2001267825A1 (en) | 2000-06-29 | 2002-01-08 | Shionogi And Co., Ltd. | Remedies for cirrhosis |
| WO2002050034A2 (en) * | 2000-12-18 | 2002-06-27 | Eli Lilly And Company | Tetracyclic carbazole derivates and their use as spla2 inhibitors |
| TWI314457B (de) * | 2001-03-19 | 2009-09-11 | Shionogi & Co | |
| AUPS282602A0 (en) | 2002-06-07 | 2002-06-27 | Garvan Institute Of Medical Research | Method of inhibiting cell proliferation |
| WO2006046779A1 (ja) | 2004-10-29 | 2006-05-04 | Zeria Pharmaceutical Co., Ltd. | カルバゾール誘導体、その溶媒和物、又は薬学的に許容されるその塩 |
| DK3307323T3 (da) | 2015-06-15 | 2022-08-15 | Raziel Therapeutics Ltd | Carbazolderivater til behandling af fibrotiske sygdomme og relaterede symptomer, og tilstande deraf |
| CN112409493B (zh) * | 2020-08-12 | 2022-09-30 | 浙江工业大学 | 一种重组融合酶及其在乙醛酸甲酯合成中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3479391A (en) * | 1966-10-03 | 1969-11-18 | Squibb & Sons Inc | Delta**3,14-17alpha-hydroxy-norprogesterone and esters |
| US3979391A (en) * | 1972-11-22 | 1976-09-07 | Sterling Drug Inc. | 1,2,3,4-Tetrahydrocarbazoles |
| US3939177A (en) * | 1972-11-22 | 1976-02-17 | Sterling Drug Inc. | 4-Aminomethyl-9-benzyl-1,2,3,4-tetrahydrocarbazoles |
| US5420289A (en) * | 1989-10-27 | 1995-05-30 | American Home Products Corporation | Substituted indole-, indene-, pyranoindole- and tetrahydrocarbazole-alkanoic acid derivatives as inhibitors of PLA2 and lipoxygenase |
| IL109309A (en) * | 1993-04-16 | 2000-06-29 | Lilly Co Eli | 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them |
| IL109311A0 (en) * | 1993-04-16 | 1994-07-31 | Lilly Co Eli | 1H-indole-3-acetamide sPla2 inhibitors |
-
1997
- 1997-10-23 KR KR1019990703309A patent/KR20000049210A/ko not_active Application Discontinuation
- 1997-10-23 CA CA002269203A patent/CA2269203A1/en not_active Abandoned
- 1997-10-23 NZ NZ335246A patent/NZ335246A/en unknown
- 1997-10-23 CZ CZ991368A patent/CZ136899A3/cs unknown
- 1997-10-23 WO PCT/US1997/019183 patent/WO1998018464A1/en not_active Application Discontinuation
- 1997-10-23 TR TR1999/00956T patent/TR199900956T2/xx unknown
- 1997-10-23 EA EA199900305A patent/EA003992B1/ru not_active IP Right Cessation
- 1997-10-23 YU YU19299A patent/YU19299A/sh unknown
- 1997-10-23 BR BR9713261-6A patent/BR9713261A/pt unknown
- 1997-10-23 PL PL97332896A patent/PL332896A1/xx unknown
- 1997-10-23 IL IL12948197A patent/IL129481A0/xx unknown
- 1997-10-23 CN CN97198834A patent/CN1233176A/zh active Pending
- 1997-10-23 AU AU51494/98A patent/AU734096B2/en not_active Ceased
- 1997-10-23 JP JP10520585A patent/JP2001503055A/ja active Pending
- 1997-10-24 PE PE1997000950A patent/PE10999A1/es not_active Application Discontinuation
- 1997-10-27 ID IDP973534A patent/ID18685A/id unknown
- 1997-10-28 AR ARP970104997A patent/AR010050A1/es active IP Right Grant
- 1997-10-28 CO CO97063171A patent/CO4920250A1/es unknown
- 1997-10-29 ES ES97308645T patent/ES2202560T3/es not_active Expired - Lifetime
- 1997-10-29 PT PT97308645T patent/PT839806E/pt unknown
- 1997-10-29 DK DK97308645T patent/DK0839806T3/da active
- 1997-10-29 EP EP97308645A patent/EP0839806B1/de not_active Expired - Lifetime
- 1997-10-29 DE DE69723393T patent/DE69723393T2/de not_active Expired - Lifetime
- 1997-10-29 AT AT97308645T patent/ATE244703T1/de active
- 1997-10-30 TW TW086116217A patent/TW513428B/zh not_active IP Right Cessation
-
1999
- 1999-04-16 NO NO19991831A patent/NO314899B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0839806B1 (de) | 2003-07-09 |
| BR9713261A (pt) | 2000-03-28 |
| JP2001503055A (ja) | 2001-03-06 |
| PT839806E (pt) | 2003-11-28 |
| AR010050A1 (es) | 2000-05-17 |
| NZ335246A (en) | 2001-09-28 |
| NO991831L (no) | 1999-06-21 |
| CO4920250A1 (es) | 2000-05-29 |
| AU5149498A (en) | 1998-05-22 |
| EP0839806A1 (de) | 1998-05-06 |
| DK0839806T3 (da) | 2003-10-27 |
| NO314899B1 (no) | 2003-06-10 |
| AU734096B2 (en) | 2001-06-07 |
| EA003992B1 (ru) | 2003-12-25 |
| DE69723393T2 (de) | 2004-06-09 |
| WO1998018464A1 (en) | 1998-05-07 |
| EA199900305A1 (ru) | 1999-12-29 |
| PL332896A1 (en) | 1999-10-25 |
| ID18685A (id) | 1998-04-30 |
| NO991831D0 (no) | 1999-04-16 |
| KR20000049210A (ko) | 2000-07-25 |
| CZ136899A3 (cs) | 1999-09-15 |
| YU19299A (sh) | 2000-03-21 |
| PE10999A1 (es) | 1999-02-10 |
| TW513428B (en) | 2002-12-11 |
| TR199900956T2 (xx) | 1999-07-21 |
| ES2202560T3 (es) | 2004-04-01 |
| CN1233176A (zh) | 1999-10-27 |
| CA2269203A1 (en) | 1998-05-07 |
| DE69723393D1 (de) | 2003-08-14 |
| IL129481A0 (en) | 2000-02-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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