IL129481A0 - Substituted tricyclics - Google Patents

Substituted tricyclics

Info

Publication number
IL129481A0
IL129481A0 IL12948197A IL12948197A IL129481A0 IL 129481 A0 IL129481 A0 IL 129481A0 IL 12948197 A IL12948197 A IL 12948197A IL 12948197 A IL12948197 A IL 12948197A IL 129481 A0 IL129481 A0 IL 129481A0
Authority
IL
Israel
Prior art keywords
substituted tricyclics
tricyclics
substituted
Prior art date
Application number
IL12948197A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL129481A0 publication Critical patent/IL129481A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572Five-membered rings
    • C07F9/5728Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Pyridine Compounds (AREA)
IL12948197A 1996-10-30 1997-10-23 Substituted tricyclics IL129481A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2984996P 1996-10-30 1996-10-30
PCT/US1997/019183 WO1998018464A1 (en) 1996-10-30 1997-10-23 Substituted tricyclics

Publications (1)

Publication Number Publication Date
IL129481A0 true IL129481A0 (en) 2000-02-29

Family

ID=21851210

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12948197A IL129481A0 (en) 1996-10-30 1997-10-23 Substituted tricyclics

Country Status (26)

Country Link
EP (1) EP0839806B1 (xx)
JP (1) JP2001503055A (xx)
KR (1) KR20000049210A (xx)
CN (1) CN1233176A (xx)
AR (1) AR010050A1 (xx)
AT (1) ATE244703T1 (xx)
AU (1) AU734096B2 (xx)
BR (1) BR9713261A (xx)
CA (1) CA2269203A1 (xx)
CO (1) CO4920250A1 (xx)
CZ (1) CZ136899A3 (xx)
DE (1) DE69723393T2 (xx)
DK (1) DK0839806T3 (xx)
EA (1) EA003992B1 (xx)
ES (1) ES2202560T3 (xx)
ID (1) ID18685A (xx)
IL (1) IL129481A0 (xx)
NO (1) NO314899B1 (xx)
NZ (1) NZ335246A (xx)
PE (1) PE10999A1 (xx)
PL (1) PL332896A1 (xx)
PT (1) PT839806E (xx)
TR (1) TR199900956T2 (xx)
TW (1) TW513428B (xx)
WO (1) WO1998018464A1 (xx)
YU (1) YU19299A (xx)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610728B2 (en) * 1997-08-28 2003-08-26 Eli Lilly And Company Method for treatment of non-rheumatoid arthritis
CN1303384A (zh) 1998-03-31 2001-07-11 盐野义制药株式会社 吡咯并[1,2-a]吡嗪sPLA2抑制剂
IL129484A0 (en) * 1998-04-17 2000-02-29 Lilly Co Eli Substituted tricyclics
DZ2769A1 (fr) * 1998-04-17 2003-12-01 Lilly Co Eli Composés tricycliques substitués.
HUP0102243A2 (hu) 1998-05-01 2001-10-28 Eli Lilly And Co. sPLA2-inhibitor vegyületek betegség kezelésére
US6472389B1 (en) 1998-05-21 2002-10-29 Shionogi & Co., Ltd. Pyrrolo[1,2-b] pyridazine derivatives having sPLA2 inhibitory effect
CA2346334A1 (en) 1998-10-14 2000-04-20 Shionogi & Co., Ltd. Composition for treating or preventing ischemia reperfusion injury
AU1928800A (en) * 1998-12-22 2000-07-12 Eli Lilly And Company Substituted tricyclics
US6703385B1 (en) 1999-07-19 2004-03-09 Shionogi & Co., Ltd. Tricyclic compounds having sPLA2-inhibitory activities
WO2001009130A1 (fr) 1999-08-02 2001-02-08 Shionogi & Co., Ltd. COMPOSES TRICYCLIQUES A ACTIVITES INHIBANT sPLA¿2?
JP4623483B2 (ja) 1999-08-23 2011-02-02 塩野義製薬株式会社 sPLA2阻害作用を有するピロロトリアジン誘導体
MY125942A (en) 1999-09-07 2006-09-29 Upjohn Co Aminoalkoxy carbazoles for the treatment of cns diseases
AU1304801A (en) 1999-11-15 2001-05-30 Shionogi & Co., Ltd. Tricyclic azaindolizine derivatives having an SPLA2- inhibiting effect
EP1259260A1 (en) * 2000-01-06 2002-11-27 Eli Lilly And Company Combination therapy for the treatment of inflammatory and respiratory diseases
US6967200B2 (en) 2000-06-29 2005-11-22 Shionogi & Co., Ltd. Remedies for cirrhosis
AU2001267823A1 (en) 2000-06-29 2002-01-08 Shionogi And Co., Ltd. Compounds exhibiting x-type spla2 inhibiting effect
EP1345898A2 (en) 2000-12-18 2003-09-24 Eli Lilly And Company Teracyclic carbazole derivates and their use as spla2 inhibitors
TWI314457B (xx) * 2001-03-19 2009-09-11 Shionogi & Co
AUPS282602A0 (en) 2002-06-07 2002-06-27 Garvan Institute Of Medical Research Method of inhibiting cell proliferation
ATE534646T1 (de) 2004-10-29 2011-12-15 Zeria Pharm Co Ltd Carbazolderivat, solvat davon und pharmazeutisch unbedenkliches salz davon
ES2924728T3 (es) * 2015-06-15 2022-10-10 Raziel Therapeutics Ltd Derivados de carbazol para el tratamiento de enfermedades fibróticas, así como de síntomas y afecciones relacionados con las mismas
CN112409493B (zh) * 2020-08-12 2022-09-30 浙江工业大学 一种重组融合酶及其在乙醛酸甲酯合成中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3479391A (en) * 1966-10-03 1969-11-18 Squibb & Sons Inc Delta**3,14-17alpha-hydroxy-norprogesterone and esters
US3939177A (en) * 1972-11-22 1976-02-17 Sterling Drug Inc. 4-Aminomethyl-9-benzyl-1,2,3,4-tetrahydrocarbazoles
US3979391A (en) * 1972-11-22 1976-09-07 Sterling Drug Inc. 1,2,3,4-Tetrahydrocarbazoles
US5420289A (en) * 1989-10-27 1995-05-30 American Home Products Corporation Substituted indole-, indene-, pyranoindole- and tetrahydrocarbazole-alkanoic acid derivatives as inhibitors of PLA2 and lipoxygenase
IL109311A0 (en) * 1993-04-16 1994-07-31 Lilly Co Eli 1H-indole-3-acetamide sPla2 inhibitors
IL109309A (en) * 1993-04-16 2000-06-29 Lilly Co Eli 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
NO991831D0 (no) 1999-04-16
DE69723393T2 (de) 2004-06-09
NZ335246A (en) 2001-09-28
EP0839806A1 (en) 1998-05-06
EA199900305A1 (ru) 1999-12-29
CO4920250A1 (es) 2000-05-29
ID18685A (id) 1998-04-30
AU734096B2 (en) 2001-06-07
ATE244703T1 (de) 2003-07-15
WO1998018464A1 (en) 1998-05-07
EP0839806B1 (en) 2003-07-09
CA2269203A1 (en) 1998-05-07
AU5149498A (en) 1998-05-22
DE69723393D1 (de) 2003-08-14
PL332896A1 (en) 1999-10-25
CZ136899A3 (cs) 1999-09-15
NO991831L (no) 1999-06-21
NO314899B1 (no) 2003-06-10
TR199900956T2 (xx) 1999-07-21
DK0839806T3 (da) 2003-10-27
JP2001503055A (ja) 2001-03-06
AR010050A1 (es) 2000-05-17
KR20000049210A (ko) 2000-07-25
PE10999A1 (es) 1999-02-10
PT839806E (pt) 2003-11-28
TW513428B (en) 2002-12-11
YU19299A (sh) 2000-03-21
BR9713261A (pt) 2000-03-28
ES2202560T3 (es) 2004-04-01
EA003992B1 (ru) 2003-12-25
CN1233176A (zh) 1999-10-27

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