DE69723393D1 - Substituierte tricyclische Verbindungen - Google Patents
Substituierte tricyclische VerbindungenInfo
- Publication number
- DE69723393D1 DE69723393D1 DE69723393T DE69723393T DE69723393D1 DE 69723393 D1 DE69723393 D1 DE 69723393D1 DE 69723393 T DE69723393 T DE 69723393T DE 69723393 T DE69723393 T DE 69723393T DE 69723393 D1 DE69723393 D1 DE 69723393D1
- Authority
- DE
- Germany
- Prior art keywords
- tricyclic compounds
- substituted tricyclic
- substituted
- compounds
- tricyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- C07F9/5728—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Fats And Perfumes (AREA)
- Steroid Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2984996P | 1996-10-30 | 1996-10-30 | |
| US29849P | 1996-10-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69723393D1 true DE69723393D1 (de) | 2003-08-14 |
| DE69723393T2 DE69723393T2 (de) | 2004-06-09 |
Family
ID=21851210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69723393T Expired - Lifetime DE69723393T2 (de) | 1996-10-30 | 1997-10-29 | Substituierte tricyclische Verbindungen |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP0839806B1 (de) |
| JP (1) | JP2001503055A (de) |
| KR (1) | KR20000049210A (de) |
| CN (1) | CN1233176A (de) |
| AR (1) | AR010050A1 (de) |
| AT (1) | ATE244703T1 (de) |
| AU (1) | AU734096B2 (de) |
| BR (1) | BR9713261A (de) |
| CA (1) | CA2269203A1 (de) |
| CO (1) | CO4920250A1 (de) |
| CZ (1) | CZ136899A3 (de) |
| DE (1) | DE69723393T2 (de) |
| DK (1) | DK0839806T3 (de) |
| EA (1) | EA003992B1 (de) |
| ES (1) | ES2202560T3 (de) |
| ID (1) | ID18685A (de) |
| IL (1) | IL129481A0 (de) |
| NO (1) | NO314899B1 (de) |
| NZ (1) | NZ335246A (de) |
| PE (1) | PE10999A1 (de) |
| PL (1) | PL332896A1 (de) |
| PT (1) | PT839806E (de) |
| TR (1) | TR199900956T2 (de) |
| TW (1) | TW513428B (de) |
| WO (1) | WO1998018464A1 (de) |
| YU (1) | YU19299A (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6610728B2 (en) * | 1997-08-28 | 2003-08-26 | Eli Lilly And Company | Method for treatment of non-rheumatoid arthritis |
| US6407104B1 (en) | 1998-03-31 | 2002-06-18 | Shionogi & Co., Ltd. | Pyrrolo[1,2-a]pyrazine spla2 inhibitor |
| DZ2769A1 (fr) * | 1998-04-17 | 2003-12-01 | Lilly Co Eli | Composés tricycliques substitués. |
| IL129484A0 (en) * | 1998-04-17 | 2000-02-29 | Lilly Co Eli | Substituted tricyclics |
| AU3656299A (en) | 1998-05-01 | 1999-11-23 | Eli Lilly And Company | Spla2 inhibitor compounds for treatment of disease |
| CN1302300A (zh) | 1998-05-21 | 2001-07-04 | 盐野义制药株式会社 | 吡咯并[1,2－b]哒嗪sPLA2抑制剂 |
| US7098237B1 (en) | 1998-10-14 | 2006-08-29 | Shionogi & Co., Ltd. | Remedies for ischemia reperfusion injury |
| DE69910432D1 (de) * | 1998-12-22 | 2003-09-18 | Lilly Co Eli | Substituierte pyrroloindole |
| AU6015600A (en) | 1999-07-19 | 2001-02-05 | Shionogi & Co., Ltd. | Tricyclic compounds having spla2-inhibitory activities |
| AU6023200A (en) | 1999-08-02 | 2001-02-19 | Shionogi & Co., Ltd. | Tricyclic compounds having spla2-inhibitory activities |
| JP4623483B2 (ja) | 1999-08-23 | 2011-02-02 | 塩野義製薬株式会社 | ｓＰＬＡ２阻害作用を有するピロロトリアジン誘導体 |
| MY125942A (en) | 1999-09-07 | 2006-09-29 | Upjohn Co | Aminoalkoxy carbazoles for the treatment of cns diseases |
| AU1304801A (en) | 1999-11-15 | 2001-05-30 | Shionogi & Co., Ltd. | Tricyclic azaindolizine derivatives having an SPLA2- inhibiting effect |
| AU2728301A (en) * | 2000-01-06 | 2001-07-16 | Eli Lilly And Company | Combination therapy for the treatment of inflammatory and respiratory diseases |
| US7026318B2 (en) | 2000-06-29 | 2006-04-11 | Shionogi & Co., Ltd. | Compounds exhibiting X-type sPLA2 inhibiting effect |
| AU2001267825A1 (en) | 2000-06-29 | 2002-01-08 | Shionogi And Co., Ltd. | Remedies for cirrhosis |
| CA2431028A1 (en) | 2000-12-18 | 2002-06-27 | Ho-Shen Lin | Tetracyclic carbazole derivates and their use as spla2 inhibitors |
| TWI314457B (de) * | 2001-03-19 | 2009-09-11 | Shionogi & Co | |
| AUPS282602A0 (en) | 2002-06-07 | 2002-06-27 | Garvan Institute Of Medical Research | Method of inhibiting cell proliferation |
| CN101048402B (zh) | 2004-10-29 | 2011-11-09 | 泽里新药工业株式会社 | 咔唑衍生物、其溶剂合物或其药学上允许的盐 |
| US10632102B2 (en) | 2015-06-15 | 2020-04-28 | Raziel Therapeutics Ltd | Carbazole derivatives for the treatment of fibrotic diseases and related symptoms, and conditions thereof |
| CN112409493B (zh) * | 2020-08-12 | 2022-09-30 | 浙江工业大学 | 一种重组融合酶及其在乙醛酸甲酯合成中的应用 |
| US12208031B2 (en) | 2020-10-21 | 2025-01-28 | Purewick Corporation | Adapters for fluid collection devices |
| US12440370B2 (en) | 2020-10-21 | 2025-10-14 | Purewick Corporation | Apparatus with compressible casing for receiving discharged urine |
| US12257174B2 (en) | 2020-10-21 | 2025-03-25 | Purewick Corporation | Fluid collection assemblies including at least one of a protrusion or at least one expandable material |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3479391A (en) * | 1966-10-03 | 1969-11-18 | Squibb & Sons Inc | Delta**3,14-17alpha-hydroxy-norprogesterone and esters |
| US3939177A (en) * | 1972-11-22 | 1976-02-17 | Sterling Drug Inc. | 4-Aminomethyl-9-benzyl-1,2,3,4-tetrahydrocarbazoles |
| US3979391A (en) * | 1972-11-22 | 1976-09-07 | Sterling Drug Inc. | 1,2,3,4-Tetrahydrocarbazoles |
| US5420289A (en) * | 1989-10-27 | 1995-05-30 | American Home Products Corporation | Substituted indole-, indene-, pyranoindole- and tetrahydrocarbazole-alkanoic acid derivatives as inhibitors of PLA2 and lipoxygenase |
| IL109311A0 (en) * | 1993-04-16 | 1994-07-31 | Lilly Co Eli | 1H-indole-3-acetamide sPla2 inhibitors |
| IL109309A (en) * | 1993-04-16 | 2000-06-29 | Lilly Co Eli | 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them |
-
1997
- 1997-10-23 BR BR9713261-6A patent/BR9713261A/pt unknown
- 1997-10-23 YU YU19299A patent/YU19299A/sh unknown
- 1997-10-23 WO PCT/US1997/019183 patent/WO1998018464A1/en not_active Ceased
- 1997-10-23 EA EA199900305A patent/EA003992B1/ru not_active IP Right Cessation
- 1997-10-23 PL PL97332896A patent/PL332896A1/xx unknown
- 1997-10-23 JP JP10520585A patent/JP2001503055A/ja active Pending
- 1997-10-23 TR TR1999/00956T patent/TR199900956T2/xx unknown
- 1997-10-23 KR KR1019990703309A patent/KR20000049210A/ko not_active Ceased
- 1997-10-23 CN CN97198834A patent/CN1233176A/zh active Pending
- 1997-10-23 CZ CZ991368A patent/CZ136899A3/cs unknown
- 1997-10-23 CA CA002269203A patent/CA2269203A1/en not_active Abandoned
- 1997-10-23 IL IL12948197A patent/IL129481A0/xx unknown
- 1997-10-23 AU AU51494/98A patent/AU734096B2/en not_active Ceased
- 1997-10-23 NZ NZ335246A patent/NZ335246A/en unknown
- 1997-10-24 PE PE1997000950A patent/PE10999A1/es not_active Application Discontinuation
- 1997-10-27 ID IDP973534A patent/ID18685A/id unknown
- 1997-10-28 AR ARP970104997A patent/AR010050A1/es active IP Right Grant
- 1997-10-28 CO CO97063171A patent/CO4920250A1/es unknown
- 1997-10-29 EP EP97308645A patent/EP0839806B1/de not_active Expired - Lifetime
- 1997-10-29 DK DK97308645T patent/DK0839806T3/da active
- 1997-10-29 ES ES97308645T patent/ES2202560T3/es not_active Expired - Lifetime
- 1997-10-29 DE DE69723393T patent/DE69723393T2/de not_active Expired - Lifetime
- 1997-10-29 AT AT97308645T patent/ATE244703T1/de active
- 1997-10-29 PT PT97308645T patent/PT839806E/pt unknown
- 1997-10-30 TW TW086116217A patent/TW513428B/zh not_active IP Right Cessation
-
1999
- 1999-04-16 NO NO19991831A patent/NO314899B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PL332896A1 (en) | 1999-10-25 |
| TW513428B (en) | 2002-12-11 |
| KR20000049210A (ko) | 2000-07-25 |
| WO1998018464A1 (en) | 1998-05-07 |
| YU19299A (sh) | 2000-03-21 |
| DE69723393T2 (de) | 2004-06-09 |
| JP2001503055A (ja) | 2001-03-06 |
| PE10999A1 (es) | 1999-02-10 |
| DK0839806T3 (da) | 2003-10-27 |
| BR9713261A (pt) | 2000-03-28 |
| IL129481A0 (en) | 2000-02-29 |
| AU734096B2 (en) | 2001-06-07 |
| PT839806E (pt) | 2003-11-28 |
| CO4920250A1 (es) | 2000-05-29 |
| AR010050A1 (es) | 2000-05-17 |
| ATE244703T1 (de) | 2003-07-15 |
| ES2202560T3 (es) | 2004-04-01 |
| CA2269203A1 (en) | 1998-05-07 |
| EA003992B1 (ru) | 2003-12-25 |
| NZ335246A (en) | 2001-09-28 |
| ID18685A (id) | 1998-04-30 |
| EP0839806A1 (de) | 1998-05-06 |
| CN1233176A (zh) | 1999-10-27 |
| EA199900305A1 (ru) | 1999-12-29 |
| NO991831L (no) | 1999-06-21 |
| CZ136899A3 (cs) | 1999-09-15 |
| NO314899B1 (no) | 2003-06-10 |
| EP0839806B1 (de) | 2003-07-09 |
| AU5149498A (en) | 1998-05-22 |
| NO991831D0 (no) | 1999-04-16 |
| TR199900956T2 (xx) | 1999-07-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336 |
|
| 8328 | Change in the person/name/address of the agent |
Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN |