HUT61047A - Process for producing genetic structures for the expression of nerve cell growth factor in eucaryotic cells - Google Patents

Process for producing genetic structures for the expression of nerve cell growth factor in eucaryotic cells Download PDF

Info

Publication number
HUT61047A
HUT61047A HU907174A HU717490A HUT61047A HU T61047 A HUT61047 A HU T61047A HU 907174 A HU907174 A HU 907174A HU 717490 A HU717490 A HU 717490A HU T61047 A HUT61047 A HU T61047A
Authority
HU
Hungary
Prior art keywords
ngf
plasmid
human
fragment
vector
Prior art date
Application number
HU907174A
Other languages
English (en)
Hungarian (hu)
Other versions
HU907174D0 (en
Inventor
Valle Francesco Della
Lanfranco Callegaro
Allesandro Negro
Original Assignee
Fidia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Spa filed Critical Fidia Spa
Publication of HU907174D0 publication Critical patent/HU907174D0/hu
Publication of HUT61047A publication Critical patent/HUT61047A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU907174A 1989-11-16 1990-11-16 Process for producing genetic structures for the expression of nerve cell growth factor in eucaryotic cells HUT61047A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT04856489A IT1238348B (it) 1989-11-16 1989-11-16 Processo per la preparazione di costrutti genetici per l'espressione del fattore di crescita nervoso in cellule eucariote.

Publications (2)

Publication Number Publication Date
HU907174D0 HU907174D0 (en) 1991-05-28
HUT61047A true HUT61047A (en) 1992-11-30

Family

ID=11267348

Family Applications (1)

Application Number Title Priority Date Filing Date
HU907174A HUT61047A (en) 1989-11-16 1990-11-16 Process for producing genetic structures for the expression of nerve cell growth factor in eucaryotic cells

Country Status (22)

Country Link
US (1) US5457034A (https=)
EP (1) EP0432510B1 (https=)
JP (2) JP3121611B2 (https=)
KR (1) KR910009929A (https=)
CN (1) CN1051934A (https=)
AR (1) AR246983A1 (https=)
AT (1) ATE214735T1 (https=)
CA (1) CA2030108C (https=)
DE (1) DE69033937T2 (https=)
ES (1) ES2173856T3 (https=)
FI (1) FI905691A7 (https=)
HU (1) HUT61047A (https=)
IE (1) IE904120A1 (https=)
IL (1) IL96347A (https=)
IT (1) IT1238348B (https=)
NZ (1) NZ236058A (https=)
PE (1) PE28191A1 (https=)
PL (1) PL287811A1 (https=)
PT (1) PT95911B (https=)
TW (1) TW205069B (https=)
YU (1) YU217890A (https=)
ZA (1) ZA909122B (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169762A (en) * 1983-03-03 1992-12-08 Genentech, Inc. Human nerve growth factor by recombinant technology
US6090781A (en) * 1996-11-06 2000-07-18 Genentech, Inc. Stabilizing formulation for NGF
US6964947B1 (en) * 1995-11-07 2005-11-15 Genentech, Inc. Stabilizing formulation for NGF
JP4486256B2 (ja) * 1998-10-22 2010-06-23 ザ・ジェネラル・ホスピタル・コーポレイション 副甲状腺ホルモン（ＰＴＨ）および副甲状腺ホルモン関連ペプチド（ＰＴＨｒＰ）の生物活性ペプチドおよびペプチド誘導体
WO2001023521A2 (en) * 1999-09-29 2001-04-05 The General Hospital Corporation Polypeptide derivatives of parathyroid hormone (pth)
ATE412670T1 (de) 1999-09-29 2008-11-15 Gen Hospital Corp Parathyroid hormon (pth) polypeptidderivate
AU2001279073B2 (en) 2000-07-28 2006-08-24 Christopher J. Murphy Transplant media
AU2002339843B2 (en) * 2001-07-23 2007-12-06 The General Hospital Corporation Conformationally constrained parathyroid hormone (PTH) analogs
US7795220B2 (en) 2003-03-19 2010-09-14 The General Hospital Corporation Conformationally constrained parathyroid hormones with alpha-helix stabilizers
JP4871128B2 (ja) 2003-07-17 2012-02-08 ザ ジェネラル ホスピタル コーポレイション 高次構造的に制約された副甲状腺ホルモン（ｐｔｈ）アナログ
US20070207209A1 (en) * 2004-08-27 2007-09-06 Murphy Christopher J Trophic factor combinations for nervous system treatment
WO2008019062A2 (en) * 2006-08-04 2008-02-14 The General Hospital Corporation Polypeptide derivatives of parathyroid hormone (pth)
CN101260398B (zh) * 2007-03-07 2013-06-05 舒泰神（北京）生物制药股份有限公司 神经生长因子基因定位改造动物及其制备方法和应用
CN104072606B (zh) * 2007-08-01 2017-09-22 总医院有限公司 利用g蛋白偶联受体和相关组合物的筛选方法
CN101927012B (zh) * 2009-06-26 2013-08-14 丽珠医药集团股份有限公司 神经生长因子的病毒灭活方法
MX358161B (es) 2010-05-13 2018-08-06 The General Hospital Corp Star Analogos de hormona paratiroidea y usos para los mismos.
CN102816766A (zh) * 2012-05-04 2012-12-12 沈阳医学院 蛇毒神经生长因子活性多肽的筛选方法
WO2023004784A1 (zh) * 2021-07-30 2023-02-02 成都优洛生物科技有限公司 一种重组cho细胞、其构建方法、利用其的检测系统和方法
CN115894705A (zh) * 2021-09-30 2023-04-04 三生国健药业（上海）股份有限公司 一种β-NGF融合蛋白、其制备方法及用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK161152C (da) * 1983-03-03 1991-11-11 Genentech Inc Polypeptid med egenskaber som human beta-nervevaekstfaktor og fremgangsmaade til fremstilling deraf, dna-isolat omfattende en sekvens som koder for polypeptidet, replicerbar udtrykkelsesvektor for dna-sekvensen, rekombinant vaertscelle transformeret med vektoren, farmaceutisk praeparat indeholdende polypeptidet og fremg. der omfatter anvendelsen af polypeptidet til fremst. af et farmaceutisk praeparat
US4796580A (en) * 1987-09-11 1989-01-10 Allied-Signal Inc. Idle control valve for use with a throttle assembly of an internal combustion engine
JPH01211490A (ja) * 1988-02-19 1989-08-24 Tosoh Corp ヒト神経成長因子遺伝子セグメント
US5272063A (en) * 1988-11-22 1993-12-21 Syntex (U.S.A.) Inc. Process of making human nerve growth factor

Also Published As

Publication number Publication date
PE28191A1 (es) 1991-10-28
HU907174D0 (en) 1991-05-28
YU217890A (sh) 1993-05-28
IE904120A1 (en) 1991-05-22
CA2030108A1 (en) 1991-05-17
KR910009929A (ko) 1991-06-28
US5457034A (en) 1995-10-10
DE69033937D1 (de) 2002-04-25
PT95911B (pt) 1998-01-30
JP2001000194A (ja) 2001-01-09
CA2030108C (en) 1998-04-28
AU6655890A (en) 1991-05-23
DE69033937T2 (de) 2002-11-14
PL287811A1 (en) 1991-12-02
IT8948564A0 (it) 1989-11-16
ZA909122B (en) 1991-09-25
FI905691A0 (fi) 1990-11-16
AR246983A1 (es) 1994-10-31
CN1051934A (zh) 1991-06-05
FI905691L (fi) 1991-05-17
IT1238348B (it) 1993-07-13
FI905691A7 (fi) 1991-05-17
PT95911A (pt) 1991-09-13
JPH03224490A (ja) 1991-10-03
EP0432510A1 (en) 1991-06-19
IT8948564A1 (it) 1991-05-16
TW205069B (https=) 1993-05-01
IL96347A0 (en) 1991-08-16
ES2173856T3 (es) 2002-11-01
IL96347A (en) 1997-11-20
JP3121611B2 (ja) 2001-01-09
ATE214735T1 (de) 2002-04-15
AU645998B2 (en) 1994-02-03
NZ236058A (en) 1993-04-28
EP0432510B1 (en) 2002-03-20

Similar Documents

Publication Publication Date Title
JP3276933B2 (ja) エリスロポエチン活性を有する糖蛋白質の製造方法
HUT61047A (en) Process for producing genetic structures for the expression of nerve cell growth factor in eucaryotic cells
EP1961425B1 (en) Methods and erythropoeitin analogs for the prevention and treatment of anemia
US7973009B2 (en) Methods and compositions for the prevention and treatment of anemia
AU2001255516A1 (en) Methods and compositions for the prevention and treatment of anemia
EP0741188A2 (en) Single chain insulin with high bioactivity
IL196645A (en) Using the Hyperglycosylic Erythropoietin Analog to prepare a pharmaceutical composition to raise and maintain hematocrit level
EP0446931A1 (en) Human ciliary neuronotrophic factor, DNA sequence encoding the factor, and production of the factor by recombinant technology
EP0444638A2 (en) Process for the expression of human nerve growth factor in arthropoda frugiperda cells by infection with recombinant baculovirus
AU612594B2 (en) Human prorelaxin
RU2261276C2 (ru) Выделенная молекула днк, кодирующая эритропоэтин человека, (варианты), экспрессирующий плазмидный или вирусный днк-вектор, гликопротеид эритропоэтин (варианты) и способ его получения, фармацевтическая композиция (варианты), линия клеток млекопитающего (варианты)
HK1127275A (en) Methods and compositions for the prevention and treatment of anemia

Legal Events

Date Code Title Description
DFD9 Temporary protection cancelled due to non-payment of fee