HUP9802209A3 - Carrier particles for use in dry powder inhalers - Google Patents

Carrier particles for use in dry powder inhalers

Info

Publication number
HUP9802209A3
HUP9802209A3 HU9802209A HUP9802209A HUP9802209A3 HU P9802209 A3 HUP9802209 A3 HU P9802209A3 HU 9802209 A HU9802209 A HU 9802209A HU P9802209 A HUP9802209 A HU P9802209A HU P9802209 A3 HUP9802209 A3 HU P9802209A3
Authority
HU
Hungary
Prior art keywords
dry powder
carrier particles
powder inhalers
inhalers
particles
Prior art date
Application number
HU9802209A
Other languages
English (en)
Original Assignee
Vectura Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10768844&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP9802209(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vectura Ltd filed Critical Vectura Ltd
Publication of HUP9802209A2 publication Critical patent/HUP9802209A2/hu
Publication of HUP9802209A3 publication Critical patent/HUP9802209A3/hu
Publication of HU229965B1 publication Critical patent/HU229965B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7012—Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
HU9802209A 1995-01-31 1996-01-31 Száraz por inhalátorban alkalmazható hordozó részecskék HU229965B1 (hu)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9501841.2 1995-01-31
GBGB9501841.2A GB9501841D0 (en) 1995-01-31 1995-01-31 Improvements in and relating to carrier particles for use in dry powder inhalers
GB9521937.4 1995-10-26
GBGB9521937.4A GB9521937D0 (en) 1995-01-31 1995-10-26 Improvementsin and relating to carrier particles for use in dry powder inhailers
PCT/GB1996/000215 WO1996023485A1 (en) 1995-01-31 1996-01-31 Carrier particles for use in dry powder inhalers

Publications (3)

Publication Number Publication Date
HUP9802209A2 HUP9802209A2 (hu) 1999-02-01
HUP9802209A3 true HUP9802209A3 (en) 2000-06-28
HU229965B1 HU229965B1 (hu) 2015-03-30

Family

ID=10768844

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9802209A HU229965B1 (hu) 1995-01-31 1996-01-31 Száraz por inhalátorban alkalmazható hordozó részecskék

Country Status (33)

Country Link
US (5) US6153224A (hu)
EP (6) EP0806938B1 (hu)
JP (1) JP4042867B2 (hu)
KR (1) KR100500694B1 (hu)
CN (1) CN1303974C (hu)
AT (3) ATE526946T1 (hu)
AU (1) AU699131B2 (hu)
BG (1) BG101858A (hu)
BR (3) BRPI9612950B8 (hu)
CA (1) CA2211874C (hu)
CZ (1) CZ294259B6 (hu)
DE (2) DE69636961T2 (hu)
DK (3) DK1232745T3 (hu)
EA (1) EA000352B1 (hu)
EE (1) EE9700176A (hu)
ES (3) ES2213172T3 (hu)
FI (1) FI119676B (hu)
GB (2) GB9501841D0 (hu)
GE (1) GEP19991687B (hu)
HK (1) HK1084897A1 (hu)
HU (1) HU229965B1 (hu)
IS (1) IS4531A (hu)
MX (1) MX9705847A (hu)
NO (1) NO324037B1 (hu)
NZ (1) NZ300654A (hu)
PL (1) PL186757B1 (hu)
PT (3) PT806938E (hu)
SI (2) SI1232745T1 (hu)
SK (1) SK282630B6 (hu)
TR (1) TR199700722T1 (hu)
UA (1) UA61051C2 (hu)
WO (1) WO1996023485A1 (hu)
ZA (1) ZA96721B (hu)

Families Citing this family (148)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743777B1 (en) * 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
GB9322014D0 (en) * 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
GB9501841D0 (en) * 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
GB9515182D0 (en) * 1995-07-24 1995-09-20 Co Ordinated Drug Dev Improvements in and relating to powders for use in dry powder inhalers
AUPN661995A0 (en) 1995-11-16 1995-12-07 Memtec America Corporation Electrochemical cell 2
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US5871010A (en) * 1996-06-10 1999-02-16 Sarnoff Corporation Inhaler apparatus with modified surfaces for enhanced release of dry powders
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
GB9806477D0 (en) 1998-03-26 1998-05-27 Glaxo Group Ltd Improved crystals
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
US20070212422A1 (en) * 1999-11-10 2007-09-13 Manfred Keller Dry powder for inhalation
EP2266548B1 (de) * 1998-11-13 2020-05-20 Jagotec AG Trockenpulver zur inhalation
GB9827145D0 (en) * 1998-12-09 1999-02-03 Co Ordinated Drug Dev Improvements in or relating to powders
ATE294571T1 (de) * 1999-03-03 2005-05-15 Lilly Co Eli Echinocandin pharmazeutische zusammensetzungen
DK1157030T3 (da) 1999-03-03 2003-12-22 Lilly Co Eli Enchinocanidin/carbohydratkomplekser
IT1309592B1 (it) * 1999-03-05 2002-01-24 Chiesi Farma Spa Particelle veicolo modificate da utilizzarsi nella preparazione diformulazioni farmaceutiche sotto forma di polimeri per inalazione e
CZ298489B6 (cs) 1999-03-05 2007-10-17 Chiesi Farmaceutici S. P. A. Prášek pro použití v inhalátoru
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
ITMI991582A1 (it) 1999-07-16 2001-01-16 Chiesi Farma Spa Polveri costituite da particelle aventi la superficie perfettamente levigata da utilizzare come veicoli per la preparazione di miscele inala
US6586008B1 (en) 1999-08-25 2003-07-01 Advanced Inhalation Research, Inc. Use of simple amino acids to form porous particles during spray drying
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
US20010036481A1 (en) * 1999-08-25 2001-11-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
US7252840B1 (en) 1999-08-25 2007-08-07 Advanced Inhalation Research, Inc. Use of simple amino acids to form porous particles
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
WO2001026630A1 (fr) * 1999-10-12 2001-04-19 Kaken Pharmaceutical Co., Ltd. Preparations pour inhalation en poudre et leur procede de production
EP1129705A1 (en) 2000-02-17 2001-09-05 Rijksuniversiteit te Groningen Powder formulation for inhalation
AU3400501A (en) * 2000-02-28 2001-09-12 Vectura Ltd Improvements in or relating to the delivery of oral drugs
EP1274400A1 (en) * 2000-04-11 2003-01-15 Dura Pharmaceuticals, Inc. Physically stabilized dry powder formulations
GB0009469D0 (en) 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formalities for use in inhaler devices
GB0009468D0 (en) 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formulations for use in inhaler devices
CA2406206C (en) * 2000-04-17 2012-03-20 Vectura Limited Improvements in or relating to formulations for use in inhaler devices
PE20011227A1 (es) * 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
JP5698423B2 (ja) * 2000-06-27 2015-04-08 ベクトゥラ・リミテッド 医薬組成物で使用するための粒子の製造法
IL153705A0 (en) 2000-06-27 2003-07-06 Vectura Ltd Method of making particles for use in a pharmaceutical composition
JP2004509920A (ja) * 2000-09-29 2004-04-02 ボード　オブ　トラスティーズ　オペレーティング　ミシガン　ステート　ユニヴァーシティ カテコールアミン医薬組成物および方法
WO2002043702A2 (en) † 2000-11-30 2002-06-06 Vectura Limited Pharmaceutical compositions for inhalation
ES2708961T3 (es) 2000-11-30 2019-04-12 Vectura Ltd Composiciones farmacéuticas para inhalación
DE60140268D1 (de) * 2000-11-30 2009-12-03 Vectura Ltd Partikel zur verwendung in einer pharmazeutischen zusammensetzung
WO2002043693A2 (en) * 2000-11-30 2002-06-06 Vectura Limited Pharmaceutical compositions for inhalation
GB0030074D0 (en) * 2000-12-08 2001-01-24 Univ London Pharmacy Particulate inhalation carrier
WO2002056948A1 (en) 2001-01-17 2002-07-25 Vectura Limited An inhaler device
EG24184A (en) * 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
WO2003024396A2 (en) 2001-09-17 2003-03-27 Glaxo Group Limited Dry powder medicament formulations
US20030129250A1 (en) * 2001-11-20 2003-07-10 Advanced Inhalation Research Inc. Particulate compositions for improving solubility of poorly soluble agents
DK1455755T3 (da) * 2001-11-20 2013-07-15 Civitas Therapeutics Inc Forbedrede partikelsammensætning til levering i lunge
WO2003047553A1 (en) * 2001-12-07 2003-06-12 Eiffel Technologies Limited Synthesis of small particles
US6941948B2 (en) 2002-03-07 2005-09-13 Vectura Drug Delivery Medicament storage and delivery devices
US7754242B2 (en) 2002-03-20 2010-07-13 Alkermes, Inc. Inhalable sustained therapeutic formulations
AU2006220411B2 (en) * 2002-03-20 2008-06-26 Alkermes, Inc. Inhalable Sustained Therapeutic Formulations
WO2003079885A2 (en) * 2002-03-20 2003-10-02 Advanced Inhalation Research, Inc. Inhalable sustained therapeutic formulations
GB0210527D0 (en) * 2002-05-08 2002-06-19 Univ Bath Process for the treatment of particles for use in pharmaceutical formulations
US6991800B2 (en) * 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
US20050158248A1 (en) * 2002-08-21 2005-07-21 Xian-Ming Zeng Method of preparing dry powder inhalation compositions
NZ538965A (en) * 2002-08-21 2006-11-30 Norton Healthcare Ltd Dry powder inhalation compositions
GB0219511D0 (en) * 2002-08-21 2002-10-02 Norton Healthcare Ltd Method of preparing dry powder inhalation compositions
CN1694689A (zh) * 2002-09-30 2005-11-09 阿库斯菲尔公司 供吸入的缓释多孔微粒
EP1610878B1 (en) * 2003-02-21 2014-09-03 University Of Bath Process for the production of particles
AU2004231342A1 (en) 2003-04-14 2004-11-04 Vectura Ltd Dry power inhaler devices and dry power formulations for enhancing dosing efficiency
US20050026948A1 (en) * 2003-07-29 2005-02-03 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a betamimetic
US20050026886A1 (en) * 2003-07-29 2005-02-03 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a PDE IV inhibitor
GB0321607D0 (en) 2003-09-15 2003-10-15 Vectura Ltd Manufacture of pharmaceutical compositions
EP1663164A2 (en) * 2003-09-15 2006-06-07 Vectura Limited Methods for preparing pharmaceutical compositions
GB0327723D0 (en) 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
GB0326632D0 (en) 2003-11-14 2003-12-17 Jagotec Ag Dry powder formulations
CA2562585A1 (en) 2004-04-23 2005-11-10 Cydex, Inc. Dpi formulation containing sulfoalkyl ether cyclodextrin
GB0409703D0 (en) 2004-04-30 2004-06-02 Vectura Ltd Pharmaceutical compositions
WO2006055950A1 (en) * 2004-11-18 2006-05-26 Nektar Therapeutics Pharmaceutical dry powder formulation on the basis particles comprising multiple active agents
GB0425758D0 (en) * 2004-11-23 2004-12-22 Vectura Ltd Preparation of pharmaceutical compositions
KR20070119631A (ko) * 2005-02-10 2007-12-20 글락소 그룹 리미티드 사전-분류 기술을 이용한 락토오스 제조 공정 및 이로부터제조된 약제 제형
US8524734B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
MX359219B (es) 2005-05-18 2018-09-19 Raptor Pharmaceuticals Inc Fluoroquinolonas aerosolizadas y sus usos.
ITMI20051999A1 (it) 2005-10-21 2007-04-22 Eratech S R L Formulazioni inalatorie di farmaci in fora di polvere secca per somministrazione come tale o con nebulizzatore e dotate di elevata erogabilita' respirabilita' e stabilita'
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
EP1954246A4 (en) * 2005-11-11 2012-01-18 Biolab Sanus Farmaceutica Ltda SOLID PHARMACEUTICAL COMPOSITION WITH AGGLOMERATE NANOTEILES AND MANUFACTURING METHOD THEREFOR
GB0525254D0 (en) 2005-12-12 2006-01-18 Jagotec Ag Powder compositions for inhalation
WO2007070851A2 (en) * 2005-12-15 2007-06-21 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for pulmonary or nasal administration
GB0602897D0 (en) * 2006-02-13 2006-03-22 Jagotec Ag Improvements In Or Relating To Dry Powder Inhaler Devices
EP1993645A4 (en) * 2006-03-03 2011-05-18 Stc Unm DRY POWDER INHALER WITH AEROELASTIC SPREADING MECHANISM
GB0613161D0 (en) 2006-06-30 2006-08-09 Novartis Ag Organic Compounds
GB0622818D0 (en) * 2006-11-15 2006-12-27 Jagotec Ag Improvements in or relating to organic compounds
GB0625303D0 (en) * 2006-12-19 2007-01-24 Jagotec Ag Improvements in and relating to metered dose inhalers
WO2008134817A1 (en) * 2007-05-03 2008-11-13 The University Of Sydney Composite carriers for dry powder inhalation therapy
US20090048155A1 (en) 2007-08-15 2009-02-19 Endacea, Inc. Methods for preventing and treating tissue injury and sepsis associated with Yersinia pestis infection
GB0721394D0 (en) * 2007-10-31 2007-12-12 Vectura Group Plc Compositions for trating parkinson's disease
JP5603248B2 (ja) 2007-12-21 2014-10-08 エンダセア， インコーポレイテッド Ａ１アデノシン受容体アンタゴニスト
GB0801876D0 (en) * 2008-02-01 2008-03-12 Vectura Group Plc Suspension formulations
NO2252275T3 (hu) 2008-02-13 2018-04-28
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
WO2009142852A2 (en) * 2008-05-22 2009-11-26 3M Innovative Properties Company Process for manufacturing flowable powder drug compositions
US9956170B2 (en) * 2008-06-26 2018-05-01 3M Innovative Properties Company Dry powder pharmaceutical compositions for pulmonary administration, and methods of manufacturing thereof
EP2309984B1 (en) * 2008-07-02 2018-04-11 3M Innovative Properties Company Method of making a dry powder pharmaceutical composition
AU2009276498A1 (en) * 2008-07-30 2010-02-04 Stc.Unm Formulations containing large-size carrier particles for dry powder inhalation aerosols
US8629139B2 (en) 2008-10-07 2014-01-14 Mpex Pharmaceuticals, Inc. Topical use of Levofloxacin for reducing lung inflammation
CN105520922A (zh) 2008-10-07 2016-04-27 拉普特制药有限公司 用于改进的药物动力学的氟喹诺酮气雾剂制剂
EP2400950B1 (en) 2009-02-26 2019-05-22 Glaxo Group Limited Pharmaceutical formulations comprising 4-{(1 r)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol
AU2010238641A1 (en) * 2009-04-24 2011-11-10 Merck Sharp & Dohme Corp. Agglomerate formulations useful in dry powder inhalers
EP2473170B1 (en) 2009-09-04 2019-06-19 Horizon Orphan LLC Use of aerosolized levofloxacin for treating cystic fibrosis
GB0918249D0 (en) 2009-10-19 2009-12-02 Respivert Ltd Compounds
CA2779488A1 (en) 2009-11-12 2011-05-19 Stc.Unm Dry powder inhaler with flutter dispersion member
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
GB0921481D0 (en) 2009-12-08 2010-01-20 Vectura Ltd Process and product
US9877967B2 (en) 2010-01-26 2018-01-30 Endacea, Inc. Methods and pharmaceutical compositions for preventing and treating renal impairment
NO2560611T3 (hu) 2010-04-21 2018-06-02
UY33337A (es) 2010-10-18 2011-10-31 Respivert Ltd DERIVADOS SUSTITUIDOS DE 1H-PIRAZOL[ 3,4-d]PIRIMIDINA COMO INHIBIDORES DE LAS FOSFOINOSITIDA 3-QUINASAS
TW201304822A (zh) 2010-11-15 2013-02-01 Vectura Ltd 組成物及用途
WO2012073025A1 (en) 2010-11-30 2012-06-07 Vectura Limited Glucosaminoglucans such as heparin for use in the treatment of pulmonary inflammation such as copd
ES2646748T3 (es) 2010-12-07 2017-12-15 Respira Therapeutics, Inc. Inhalador de polvo seco
US10092552B2 (en) 2011-01-31 2018-10-09 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
JO3510B1 (ar) 2011-03-04 2020-07-05 Heptares Therapeutics Ltd استخدام جلايكوبيرولات لعلاج عدم انتظام دقات القلب
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
HUE060421T2 (hu) * 2012-01-25 2023-02-28 Chiesi Farm Spa Kortikoszteroidot és béta-adrenerg szert tartalmazó száraz porkészítmény inhalálással történõ beadásra
EP2809780B1 (en) 2012-02-01 2018-05-02 Protalix Ltd. Dnase i polypeptides, polynucleotides encoding same, methods of producing dnase i and uses thereof in therapy
US10463815B2 (en) 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
LT2834244T (lt) 2012-03-13 2016-11-10 Respivert Limited Kristalinės pi3 kinazės slopikliai
EP2641900A1 (en) 2012-03-20 2013-09-25 Almirall, S.A. Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
GB201305825D0 (en) 2013-03-28 2013-05-15 Vectura Ltd New use
WO2014186754A2 (en) 2013-05-16 2014-11-20 Board Of Regents The University Of Texas System Dry solid aluminum adjuvant-containing vaccines and related methods thereof
US20150044288A1 (en) 2013-07-31 2015-02-12 Windward Pharma, Inc. Aerosol tyrosine kinase inhibitor compounds and uses thereof
US9427376B2 (en) * 2013-10-10 2016-08-30 Chiesi Farmaceutici S.P.A. Process for preparing pharmaceutical formulations for inhalation comprising a high-dosage strength active ingredient
CA2936330C (en) 2014-01-10 2023-01-03 Genoa Pharmaceuticals Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
AU2015231413B2 (en) 2014-03-19 2020-04-23 Infinity Pharmaceuticals, Inc. Heterocyclic compounds for use in the treatment of PI3K-gamma mediated disorders
WO2015179369A1 (en) 2014-05-20 2015-11-26 Infinity Pharmaceuticals, Inc. Treatment of pulmonary or respiratory diseases by inhalation administration of pi3 kinase inhibitors
US10532041B2 (en) 2014-09-09 2020-01-14 Vectura Limited Formulation comprising glycopyrrolate, method and apparatus
CN107106641B (zh) 2014-10-31 2021-12-21 葛兰素史密斯克莱知识产权发展有限公司 粉末制剂
RU2661521C1 (ru) * 2014-11-26 2018-07-17 Вектура Деливери Дивайсиз Лимитед Сухопорошковый ингалятор
CN107427650A (zh) 2015-01-14 2017-12-01 瑞必治公司 粉末分散方法和装置
EP3340982B1 (en) 2015-08-26 2021-12-15 Achillion Pharmaceuticals, Inc. Compounds for treatment of immune and inflammatory disorders
AR106018A1 (es) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
SI3346990T1 (sl) 2015-09-09 2020-07-31 Vectura Limited Postopek mletja s curkom
KR20180118667A (ko) 2016-03-08 2018-10-31 메레오 바이오파마 1 리미티드 만성 폐쇄성 폐 질환의 급성 악화 치료를 위한 투약법
CA3016368A1 (en) 2016-03-08 2017-09-14 Mereo Biopharma 1 Limited Dosage regimen for the treatment of acute exacerbations of inflammatory conditions
MX2018016046A (es) 2016-06-27 2019-05-02 Achillion Pharmaceuticals Inc Quinazolina y compuestos indol para tratar trastornos medicos.
CA3083953A1 (en) 2017-12-11 2019-06-20 Board Of Regents, The University Of Texas System Dry adjuvanted immune stimulating compositions and use thereof for mucosal administration
CA3085545A1 (en) 2017-12-11 2019-06-20 Mereo Biopharma 1 Limited Use of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamide in the treatment of acute exacerbations of chronic obstructive pulmonary disease
KR20200097310A (ko) 2017-12-11 2020-08-18 메레오 바이오파마 1 리미티드 만성 폐쇄성 폐 질환의 급성 악화의 예방 또는 감소에서의 3-[5-아미노-4-(3-시아노벤조일)-피라졸-1-일]-n-시클로프로필-4-메틸벤즈아미드의 용도
KR20210018199A (ko) 2018-03-26 2021-02-17 씨4 테라퓨틱스, 인코포레이티드 이카로스의 분해를 위한 세레블론 결합제
JP2021535112A (ja) 2018-08-20 2021-12-16 アキリオン ファーマシューティカルズ，インコーポレーテッド 補体ｄ因子の医学的障害の治療のための医薬化合物
EP3866773A4 (en) 2018-10-16 2022-10-26 Georgia State University Research Foundation, Inc. CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL CONDITIONS
PL3947384T3 (pl) 2019-04-04 2024-03-25 Chiesi Farmaceutici S.P.A. Pochodne izochromenu jako inhibitory kinaz 3-fosfoinozytydów
JP2022549445A (ja) 2019-09-24 2022-11-25 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ 吸入用乾燥粉末製剤のための新規担体粒子
WO2022047047A1 (en) * 2020-08-26 2022-03-03 Cila Therapeutic Inc. Inhalable therapeutic agents
CN112451509B (zh) * 2020-12-19 2023-03-07 沈阳药科大学 一种川丁特罗吸入粉雾剂及其制备方法
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
WO2023028364A1 (en) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Targeted compositions and uses therof
WO2023196663A1 (en) * 2022-04-07 2023-10-12 Board Of Regents, The University Of Texas System Methods of preparing carrier-based dry powders for inhalation
CN115855911B (zh) * 2023-02-24 2023-06-13 湖南三友环保科技有限公司 粉末载体生物亲和性的测定方法及应用

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2533065A (en) * 1947-03-08 1950-12-05 George V Taplin Micropulverized therapeutic agents
GB786499A (en) * 1953-11-02 1957-11-20 Grace W R & Co A process of deagglomerating dried agglomerated microspheroidal gel catalyst particles
GB905723A (en) * 1959-12-10 1962-09-12 Alfred Ernest Tragham Pharmaceutical compositions comprising phenacitin
GB1132583A (en) * 1964-12-16 1968-11-06 Glaxo Lab Ltd Pharmaceutical compositions containing cephalosporins
US3957965A (en) * 1967-08-08 1976-05-18 Fisons Limited Sodium chromoglycate inhalation medicament
GB1242212A (en) * 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Drug for use in pharmaceutical composition
GB1242211A (en) * 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
GB1230087A (hu) * 1967-08-17 1971-04-28
GB1310527A (en) * 1969-06-13 1973-03-21 Fisons Ltd Comminuting apparatus
GB1381872A (en) * 1971-06-22 1975-01-29 Fisons Ltd Pharmaceutical compositions for inhalation
GB1410588A (en) * 1971-08-10 1975-10-22 Fisons Ltd Composition
IT1197640B (it) * 1983-05-03 1988-12-06 Italsil Spa Apparecchio e metodo per la purificazione di sabbie silicee mediante attrizione
EP0187433B1 (en) * 1983-08-01 1990-12-27 Teijin Limited Powdery pharmaceutical composition suitable for application to mucosa of oral or nasal cavity
IT1204826B (it) * 1986-03-04 1989-03-10 Chiesi Farma Spa Composizioni farmaceutiche per inalazione
US5376386A (en) * 1990-01-24 1994-12-27 British Technology Group Limited Aerosol carriers
GB9001635D0 (en) * 1990-01-24 1990-03-21 Ganderton David Aerosol carriers
IE67185B1 (en) * 1990-02-02 1996-03-06 Fisons Plc Propellant compositions
DE69109284T2 (de) * 1990-03-23 1995-08-24 Minnesota Mining & Mfg Verwendung von fluorierten löslichen tensiden zur herstellung von aerosolarzneimitteln mit dosierter abgabe.
GB9024366D0 (en) * 1990-11-09 1991-01-02 Glaxo Group Ltd Medicaments
DE4140689B4 (de) * 1991-12-10 2007-11-22 Boehringer Ingelheim Kg Inhalationspulver und Verfahren zu ihrer Herstellung
US5626871A (en) * 1992-06-12 1997-05-06 Teijin Limited Preparation for intratracheobronchial administration
WO1993025198A1 (en) * 1992-06-12 1993-12-23 Teijin Limited Ultrafine powder for inhalation and production thereof
GB2269992A (en) * 1992-08-14 1994-03-02 Rh Ne Poulenc Rorer Limited Powder inhalation formulations
ZA94155B (en) 1992-11-06 1995-07-11 Adcock Ingram Pharma Pharmaceutical composition
SE9203743D0 (sv) * 1992-12-11 1992-12-11 Astra Ab Efficient use
US5506203C1 (en) * 1993-06-24 2001-02-06 Astra Ab Systemic administration of a therapeutic preparation
IS1796B (is) * 1993-06-24 2001-12-31 Ab Astra Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
TW402506B (en) * 1993-06-24 2000-08-21 Astra Ab Therapeutic preparation for inhalation
GB9322014D0 (en) * 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
GB9501841D0 (en) 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
GB9515182D0 (en) * 1995-07-24 1995-09-20 Co Ordinated Drug Dev Improvements in and relating to powders for use in dry powder inhalers
CZ298489B6 (cs) * 1999-03-05 2007-10-17 Chiesi Farmaceutici S. P. A. Prášek pro použití v inhalátoru
PE20011227A1 (es) * 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
GB0009469D0 (en) * 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formalities for use in inhaler devices
IL153705A0 (en) * 2000-06-27 2003-07-06 Vectura Ltd Method of making particles for use in a pharmaceutical composition
JP3486405B2 (ja) 2001-08-10 2004-01-13 三菱重工業株式会社 減揺装置

Also Published As

Publication number Publication date
ES2278828T3 (es) 2007-08-16
DE69636961T2 (de) 2007-06-14
SI1232745T1 (sl) 2007-06-30
ZA96721B (en) 1996-08-19
CN1303974C (zh) 2007-03-14
DE69631119D1 (de) 2004-01-29
BR9607490A (pt) 2018-04-17
CA2211874C (en) 2006-08-29
EA199700153A1 (ru) 1997-12-30
EP1666023A2 (en) 2006-06-07
ATE256450T1 (de) 2004-01-15
DK1666023T3 (da) 2012-01-30
US7011818B2 (en) 2006-03-14
ATE526946T1 (de) 2011-10-15
BRPI9612950B8 (pt) 2018-04-17
NO324037B1 (no) 2007-07-30
SK282630B6 (sk) 2002-10-08
AU699131B2 (en) 1998-11-26
BG101858A (en) 1998-04-30
EP1232745A1 (en) 2002-08-21
NO973502D0 (no) 1997-07-30
CZ244397A3 (cs) 1998-01-14
JPH10513174A (ja) 1998-12-15
DE69636961D1 (de) 2007-04-19
EP2258342A3 (en) 2014-01-08
BR9607490B8 (pt) 2018-04-17
CZ294259B6 (cs) 2004-11-10
US6521260B1 (en) 2003-02-18
HUP9802209A2 (hu) 1999-02-01
US20060029552A1 (en) 2006-02-09
US20100330188A1 (en) 2010-12-30
US7718163B2 (en) 2010-05-18
EP1159955A1 (en) 2001-12-05
US8920781B2 (en) 2014-12-30
BRPI9612950B1 (hu) 2011-08-23
SI1666023T1 (sl) 2012-01-31
EP2213279A2 (en) 2010-08-04
AU4545696A (en) 1996-08-21
GEP19991687B (en) 1999-08-05
PT1666023E (pt) 2012-01-12
US20030170183A1 (en) 2003-09-11
IS4531A (is) 1997-07-25
EP0806938B1 (en) 2003-12-17
DK0806938T3 (da) 2004-04-13
TR199700722T1 (xx) 1998-02-21
NO973502L (no) 1997-09-30
ATE355822T1 (de) 2007-03-15
EE9700176A (et) 1998-02-16
PT1232745E (pt) 2007-04-30
EP2258342A2 (en) 2010-12-08
ES2375007T3 (es) 2012-02-24
EP1666023A3 (en) 2009-05-06
SK103697A3 (en) 1998-01-14
PL321572A1 (en) 1997-12-08
PT806938E (pt) 2004-05-31
KR100500694B1 (ko) 2006-03-22
BR9612950B1 (pt) 2011-08-23
MX9705847A (es) 1998-08-30
EP1666023B1 (en) 2011-10-05
NZ300654A (en) 1999-02-25
GB9501841D0 (en) 1995-03-22
EA000352B1 (ru) 1999-04-29
FI973151A0 (fi) 1997-07-30
HK1084897A1 (en) 2006-08-11
JP4042867B2 (ja) 2008-02-06
CA2211874A1 (en) 1996-08-08
PL186757B1 (pl) 2004-02-27
DE69631119T2 (de) 2004-09-16
GB9521937D0 (en) 1996-01-03
HU229965B1 (hu) 2015-03-30
EP1232745B1 (en) 2007-03-07
CN1179097A (zh) 1998-04-15
WO1996023485A1 (en) 1996-08-08
ES2213172T3 (es) 2004-08-16
FI973151A (fi) 1997-09-30
KR19980701844A (ko) 1998-06-25
EP2213279A3 (en) 2010-10-13
UA61051C2 (en) 2003-11-17
US6153224A (en) 2000-11-28
DK1232745T3 (da) 2007-07-09
EP0806938A1 (en) 1997-11-19
FI119676B (fi) 2009-02-13

Similar Documents

Publication Publication Date Title
HUP9802209A3 (en) Carrier particles for use in dry powder inhalers
GB9322014D0 (en) Improvements in and relating to carrier particles for use in dry powder inhalers
HU9502612D0 (en) Dry powder inhalator medicament carrier
HU9602818D0 (en) Dry powder inhaler
SG52348A1 (en) Dry powder inhalers
HUP9903819A3 (en) Dry powder inhaler
HUP0001799A3 (en) Dry powder inhaler
PL320825A1 (en) Prolyposomes containing inhalation powders
EP0835147A4 (en) INHALING DEVICE WITH POWDER POWDER
GB9416663D0 (en) Particle delivery
ZA957933B (en) Apparatus and methods for dispersing dry powder medicaments
GB9626263D0 (en) Powder inhaler
IL135027A0 (en) Dry powder delivery system apparatus
GB9502879D0 (en) Particle delivery
GB9605690D0 (en) Particle delivery
PL332503A1 (en) Coated particles containing preparation
AU1904692A (en) Improvements in coated perfume particles
IL114709A (en) Absorbent particles methods for the preparation thereof and absorbent devices using the same
GB9619002D0 (en) Particle delivery
GB9719093D0 (en) Improvements to dry powder inhalers
PL341319A1 (en) Apparatus for inhaling powdered substances
ZA9643B (en) Particles containing perfume
GB2316081B (en) Dispensing of particles
GB9521416D0 (en) Dry powder inhalation device
GB9716906D0 (en) Powders for use in a dry powder inhaler

Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: VECTURA LIMITED, GB

Free format text: FORMER OWNER(S): CO-ORDINATED DRUG DEVELOPMENT LIMITED, GB; VECTURA GROUP PLC, GB; VECTURA LIMITED, GB

HC9A Change of name, address

Owner name: VECTURA LIMITED, GB

Free format text: FORMER OWNER(S): CO-ORDINATED DRUG DEVELOPMENT LIMITED, GB; VECTURA GROUP PLC, GB; VECTURA LIMITED, GB