HUP9801608A2 - A 11. típusú humán papillomavírusból származó L1-fehérjét kódoló szintetikus HPV6/11-L1-hibrid-DNS - Google Patents

A 11. típusú humán papillomavírusból származó L1-fehérjét kódoló szintetikus HPV6/11-L1-hibrid-DNS

Info

Publication number
HUP9801608A2
HUP9801608A2 HU9801608A HUP9801608A HUP9801608A2 HU P9801608 A2 HUP9801608 A2 HU P9801608A2 HU 9801608 A HU9801608 A HU 9801608A HU P9801608 A HUP9801608 A HU P9801608A HU P9801608 A2 HUP9801608 A2 HU P9801608A2
Authority
HU
Hungary
Prior art keywords
protein
synthetic
human papillomavirus
papillomavirus type
hpv6
Prior art date
Application number
HU9801608A
Other languages
English (en)
Inventor
Hugh A. George
Kathryn J. Hofmann
Kathrin U. Jansen
Joseph G. Joyce
Ernest Dale Lehman
Michael P. Neeper
Original Assignee
Merck & Co. Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27022236&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP9801608(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co. Inc. filed Critical Merck & Co. Inc.
Publication of HUP9801608A2 publication Critical patent/HUP9801608A2/hu
Publication of HUP9801608A3 publication Critical patent/HUP9801608A3/hu
Publication of HU228490B1 publication Critical patent/HU228490B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

A találmány tárgyát szintetikűs DNS-mőlekűlák képezik, melyek atisztítőtt 11. típűsú hűmán papillőmavírűsból származó L1-fehérjét ésszármazékait kódőlják. A találmány tárgyát képezik tővábbá a találmány szerinti DNS-mőlekűlákat tartalmazó vektőrők, találmány szerinti DNS-mőlekűlákáltal kódőlt pőlipeptidek, a találmány szerinti DNS-mőlekűlákkal éspőlipeptidekkel reagáló ellenanyagők, a találmány szerinti mőlekűlákattartalmazó készítmények és őltóanyagők, valamint eljárásők a találmányszerinti mőlekűlák előállítására. A találmány szerinti megőldás alkalmas papillőmavírűsős fertőzésekmegelőzésére és kezelésére. ŕ
HU9801608A 1995-03-30 1996-03-26 Synthetic hpv6/11 hybrid l1 dna encoding human papillomavirus type 11 l1 protein HU228490B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41357295A 1995-03-30 1995-03-30
US41357195A 1995-03-30 1995-03-30
PCT/US1996/004117 WO1996030520A2 (en) 1995-03-30 1996-03-26 Synthetic hpv6/11 hybrid l1 dna encoding human papillomavirus type 11 l1 protein

Publications (3)

Publication Number Publication Date
HUP9801608A2 true HUP9801608A2 (hu) 1998-10-28
HUP9801608A3 HUP9801608A3 (en) 1999-04-28
HU228490B1 HU228490B1 (en) 2013-03-28

Family

ID=27022236

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9801608A HU228490B1 (en) 1995-03-30 1996-03-26 Synthetic hpv6/11 hybrid l1 dna encoding human papillomavirus type 11 l1 protein

Country Status (21)

Country Link
US (1) US6159729A (hu)
EP (1) EP0817852B1 (hu)
JP (1) JP3918877B2 (hu)
KR (1) KR100441477B1 (hu)
CN (1) CN1154732C (hu)
AT (1) ATE247712T1 (hu)
AU (1) AU708111B2 (hu)
CZ (1) CZ291375B6 (hu)
DE (1) DE69629556T2 (hu)
DK (1) DK0817852T3 (hu)
EA (1) EA000969B1 (hu)
ES (1) ES2203691T3 (hu)
HU (1) HU228490B1 (hu)
IL (1) IL117591A0 (hu)
NO (1) NO320086B1 (hu)
NZ (1) NZ306663A (hu)
PL (1) PL183299B1 (hu)
PT (1) PT817852E (hu)
SK (1) SK283998B6 (hu)
WO (1) WO1996030520A2 (hu)
ZA (1) ZA962526B (hu)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2177999C2 (ru) * 1994-09-22 2002-01-10 Мерк Энд Ко., Инк. Экспрессирующий вектор (варианты)
GB9621091D0 (en) 1996-10-09 1996-11-27 Fondation Pour Le Perfectionem Attenuated microorganisms strains and their uses
PT973546E (pt) * 1997-04-08 2004-06-30 Merck & Co Inc Formulacoes estabilizadas de virus de papiloma humano
PL347472A1 (en) * 1998-08-14 2002-04-08 Merck & Co Inc Process for purifying human papillomavirus virus-like particles
DE19840263C1 (de) * 1998-09-03 2000-05-25 Deutsches Krebsforsch Papillomviren, Mittel zu deren Nachweis sowie zur Therapie von durch sie verursachten Erkrankungen
US6380364B1 (en) 1998-11-23 2002-04-30 Loyola University Of Chicago Chimeric biotin-binding papillomavirus protein
AUPP765398A0 (en) 1998-12-11 1999-01-14 University Of Queensland, The Treatment of papillomavirus infections
DK1150712T3 (da) 1999-02-05 2009-02-02 Merck & Co Inc Vaccineformuleringer mod human papillomavirus
US7001995B1 (en) * 1999-08-25 2006-02-21 Merck & Co., Inc. Synthetic human papillomavirus genes
SI1421200T1 (sl) * 2001-08-23 2007-04-30 Merck & Co Inc Poskusi PCR fluorescentnih multipleks HPV-jev z uporabo vec fluoroforov
EP1302550A1 (en) * 2001-10-10 2003-04-16 King Car Food Industrial Co., Ltd. Method and detector for identifying subtypes of human papilloma viruses
US20040223976A1 (en) * 2003-03-07 2004-11-11 Elisabetta Bianchi Influenza virus vaccine
CN100506999C (zh) * 2003-03-24 2009-07-01 麦克公司 Hpv31l1在酵母中的优化表达
IL156670A0 (en) * 2003-06-26 2004-01-04 Zvi Zolotariov Aloe suppositories
EP1664348B8 (en) 2003-09-25 2019-06-12 Third Wave Technologies, Inc. Detection of hpv
MY140664A (en) * 2003-09-29 2010-01-15 Merck Sharp & Dohme Optimized expression of hpv 45 l1 in yeast
MY139500A (en) * 2003-11-12 2009-10-30 Merck Sharp & Dohme Optimized expression of hpv 58 l1 in yeast
PL1730175T3 (pl) * 2004-03-24 2010-09-30 Merck Sharp & Dohme Optymalizowana ekspresja L1 HPV 52 w drożdżach
ATE476528T1 (de) 2004-12-08 2010-08-15 Gen Probe Inc Nukleinsäuredetektion aus verschiedenen typen des humanen papillomavirus
CN101341257B (zh) * 2004-12-10 2012-10-10 杰纳罗生物系统有限责任公司 使用核酸探针、微珠和荧光激活的细胞分选器(facs)检测人乳头状瘤病毒(hpv)
PL1844164T3 (pl) * 2005-11-15 2010-12-31 Genoid Kft Sposób wykrywania patogenów z zastosowaniem sond typu "latarni molekularnych"
US8080643B2 (en) * 2006-09-05 2011-12-20 Third Wave Technologies, Inc. HPV primers
CN101200696B (zh) * 2007-11-14 2011-07-20 山东大学 人乳头瘤病毒的酵母增殖模型及建立方法与应用
KR20090073987A (ko) * 2007-12-31 2009-07-03 정운원 인간유두종바이러스 유전자형 검사를 위한 프라이머, 프로브 및 이를 포함하는 ｄｎａ칩, 이의 검사 방법 및 검사 키트
AU2011258501B2 (en) 2010-05-25 2016-07-07 Qiagen Gaithersburg, Inc. Fast results hybrid capture assay and associated strategically-truncated probes
WO2012065034A1 (en) 2010-11-12 2012-05-18 Merck Sharp & Dohme Corp. Enolase peptide conjugate vaccines against staphylococcus aureus
CN103717741B (zh) 2011-06-15 2016-04-13 中央大学校产学协力团 用于提高人乳头瘤病毒l1蛋白产量的方法
BR112018011331A2 (pt) 2015-12-04 2019-04-30 Xiamen Innovax Biotech Co., Ltd. mutante de proteìna l1 de papillomavirus humano tipo 11
KR20210064318A (ko) * 2018-09-26 2021-06-02 시아먼 유니버시티 Hpv 타입 51의 l1 단백질의 돌연변이체

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE122007000085I1 (de) * 1991-07-19 2008-03-27 Univ Queensland St Lucia Polynukleotidabschnitt des HPV16-Genoms
DE122007000014I1 (de) * 1993-03-09 2007-05-24 Univ Rochester Herstellung von menschlichem Papillomavirus Hüllprotein und virus-ähnlichen Teilchen

Also Published As

Publication number Publication date
CZ309197A3 (cs) 1998-02-18
NO974514D0 (no) 1997-09-29
CN1185810A (zh) 1998-06-24
PT817852E (pt) 2003-12-31
DE69629556D1 (de) 2003-09-25
CN1154732C (zh) 2004-06-23
NO974514L (no) 1997-11-27
PL183299B1 (pl) 2002-06-28
NZ306663A (en) 1999-10-28
CZ291375B6 (cs) 2003-02-12
EP0817852A2 (en) 1998-01-14
DE69629556T2 (de) 2004-06-17
SK129397A3 (en) 1998-05-06
KR100441477B1 (ko) 2004-10-06
JP3918877B2 (ja) 2007-05-23
ATE247712T1 (de) 2003-09-15
DK0817852T3 (da) 2003-11-24
AU708111B2 (en) 1999-07-29
US6159729A (en) 2000-12-12
WO1996030520A2 (en) 1996-10-03
JPH11503313A (ja) 1999-03-26
ES2203691T3 (es) 2004-04-16
EP0817852B1 (en) 2003-08-20
HUP9801608A3 (en) 1999-04-28
ZA962526B (en) 1996-09-04
SK283998B6 (sk) 2004-07-07
HU228490B1 (en) 2013-03-28
EA000969B1 (ru) 2000-08-28
KR19980703391A (ko) 1998-10-15
IL117591A0 (en) 1996-07-23
EA199700281A1 (ru) 1998-04-30
AU5527796A (en) 1996-10-16
WO1996030520A3 (en) 1996-11-07
NO320086B1 (no) 2005-10-24
PL322588A1 (en) 1998-02-02

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Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: MERCK SHARP & DOHME CORP., US

Free format text: FORMER OWNER(S): MERCK & CO., INC., US; MERCK SHARP & DOHME CORP., US; SCHERING CORPORATION, US

HC9A Change of name, address

Owner name: MERCK SHARP & DOHME CORP., US

Free format text: FORMER OWNER(S): MERCK & CO., INC., US; MERCK SHARP & DOHME CORP., US; SCHERING CORPORATION, US