HUP9800901A3 - Process, medium and cell culture system for the preparation of recombinant factor viii in a protein free medium - Google Patents

Process, medium and cell culture system for the preparation of recombinant factor viii in a protein free medium

Info

Publication number
HUP9800901A3
HUP9800901A3 HU9800901A HUP9800901A HUP9800901A3 HU P9800901 A3 HUP9800901 A3 HU P9800901A3 HU 9800901 A HU9800901 A HU 9800901A HU P9800901 A HUP9800901 A HU P9800901A HU P9800901 A3 HUP9800901 A3 HU P9800901A3
Authority
HU
Hungary
Prior art keywords
medium
preparation
cell culture
factor viii
culture system
Prior art date
Application number
HU9800901A
Other languages
English (en)
Original Assignee
Bayer Corp Berkeley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25293446&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP9800901(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Corp Berkeley filed Critical Bayer Corp Berkeley
Publication of HU9800901D0 publication Critical patent/HU9800901D0/hu
Publication of HUP9800901A2 publication Critical patent/HUP9800901A2/hu
Publication of HUP9800901A3 publication Critical patent/HUP9800901A3/hu
Publication of HU224306B1 publication Critical patent/HU224306B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/35—Polyols, e.g. glycerin, inositol
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C12N2500/95—Protein-free medium and culture conditions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
HU9800901A 1997-04-18 1998-04-17 Eljárás, tápközeg és sejttenyésztő rendszer rekombináns VIII. faktor előállítására fehérjementes közegben HU224306B1 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/844,714 US5804420A (en) 1997-04-18 1997-04-18 Preparation of recombinant Factor VIII in a protein free medium

Publications (4)

Publication Number Publication Date
HU9800901D0 HU9800901D0 (en) 1998-07-28
HUP9800901A2 HUP9800901A2 (hu) 1999-05-28
HUP9800901A3 true HUP9800901A3 (en) 2001-08-28
HU224306B1 HU224306B1 (hu) 2005-07-28

Family

ID=25293446

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9800901A HU224306B1 (hu) 1997-04-18 1998-04-17 Eljárás, tápközeg és sejttenyésztő rendszer rekombináns VIII. faktor előállítására fehérjementes közegben

Country Status (29)

Country Link
US (2) US5804420A (hu)
EP (1) EP0872487B1 (hu)
JP (1) JP4257685B2 (hu)
KR (1) KR100496111B1 (hu)
CN (1) CN1127518C (hu)
AR (1) AR012451A1 (hu)
AT (1) ATE342921T1 (hu)
AU (1) AU748731B2 (hu)
BR (1) BRPI9801092B8 (hu)
CA (1) CA2234215C (hu)
CO (1) CO4790112A1 (hu)
CZ (1) CZ295049B6 (hu)
DE (1) DE69836164T2 (hu)
DK (1) DK0872487T3 (hu)
ES (1) ES2273380T3 (hu)
HK (1) HK1018797A1 (hu)
HU (1) HU224306B1 (hu)
ID (1) ID20193A (hu)
IL (1) IL124123A (hu)
MY (1) MY115583A (hu)
NZ (1) NZ330183A (hu)
PL (1) PL192072B1 (hu)
PT (1) PT872487E (hu)
RU (1) RU2222547C2 (hu)
SK (1) SK285684B6 (hu)
TR (1) TR199800493A1 (hu)
TW (1) TW490469B (hu)
UA (1) UA66340C2 (hu)
ZA (1) ZA983234B (hu)

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US6475725B1 (en) * 1997-06-20 2002-11-05 Baxter Aktiengesellschaft Recombinant cell clones having increased stability and methods of making and using the same
US6528286B1 (en) * 1998-05-29 2003-03-04 Genentech, Inc. Mammalian cell culture process for producing glycoproteins
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US6358703B1 (en) * 1998-12-10 2002-03-19 Bayer Corporation Expression system for factor VIII
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US20050224355A1 (en) * 1999-12-23 2005-10-13 Brendon Conlan Removal of biological contaminants
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ES2252028T3 (es) * 1999-07-13 2006-05-16 Biovitrum Ab Composiciones estables del factor viii.
US6767741B1 (en) 1999-08-27 2004-07-27 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
DE60041573D1 (de) 1999-08-31 2009-04-02 Sony Computer Entertainment Inc Unterhaltungssystem, aufzeichnungsmdeium und programm
US7077942B1 (en) * 1999-12-23 2006-07-18 Gradipore Limited Removal of biological contaminants
AUPQ691400A0 (en) 2000-04-14 2000-05-11 Life Therapeutics Limited Separation of micromolecules
CA2405033A1 (en) 2000-04-18 2001-10-25 Gradipore Limited Electrophoresis separation and treatment of samples
AUPQ697300A0 (en) 2000-04-18 2000-05-11 Life Therapeutics Limited Separation apparatus
US6923896B2 (en) * 2000-09-22 2005-08-02 The Texas A&M University System Electrophoresis apparatus and method
WO2002028516A1 (en) * 2000-10-06 2002-04-11 Gradipore Limited Multi-port separation apparatus and method
AUPR222300A0 (en) * 2000-12-21 2001-01-25 Life Therapeutics Limited Electrophoresis device and method
US7220718B2 (en) 2001-08-03 2007-05-22 United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Oral treatment of hemophilia
CN105131104B (zh) 2001-10-10 2018-11-16 诺和诺德公司 肽的重构和糖缀合
CA2470511C (en) * 2001-12-21 2014-05-27 Novo Nordisk Health Care Ag Liquid composition of factor vii polypeptides
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US20040009918A1 (en) * 2002-05-03 2004-01-15 Hanne Nedergaard Stabilised solid compositions of modified factor VII
EP1517698B2 (en) 2002-06-21 2017-12-06 Novo Nordisk Health Care AG STABILISED SOLID COMPOSITIONS OF FACTOR VIIa POLYPEPTIDES
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Also Published As

Publication number Publication date
HU224306B1 (hu) 2005-07-28
CO4790112A1 (es) 1999-05-31
EP0872487A2 (en) 1998-10-21
JP4257685B2 (ja) 2009-04-22
KR100496111B1 (ko) 2005-09-09
PT872487E (pt) 2007-01-31
CN1210866A (zh) 1999-03-17
BRPI9801092B8 (pt) 2021-07-06
DK0872487T3 (da) 2007-02-05
BRPI9801092B1 (pt) 2013-04-02
BRPI9801092A (pt) 2000-01-11
CA2234215A1 (en) 1998-10-18
CZ115698A3 (cs) 1998-11-11
EP0872487B1 (en) 2006-10-18
PL192072B1 (pl) 2006-08-31
NZ330183A (en) 1999-08-30
RU2222547C2 (ru) 2004-01-27
HK1018797A1 (en) 2000-01-07
DE69836164D1 (de) 2006-11-30
CA2234215C (en) 2008-06-17
US5804420A (en) 1998-09-08
ZA983234B (en) 1998-10-22
JPH10295397A (ja) 1998-11-10
AR012451A1 (es) 2000-10-18
MY115583A (en) 2003-07-31
HUP9800901A2 (hu) 1999-05-28
SK49798A3 (en) 1998-12-02
US6171825B1 (en) 2001-01-09
AU748731B2 (en) 2002-06-13
CN1127518C (zh) 2003-11-12
ID20193A (id) 1998-10-22
UA66340C2 (uk) 2004-05-17
SK285684B6 (sk) 2007-06-07
KR19980081531A (ko) 1998-11-25
TR199800493A1 (xx) 1998-11-23
EP0872487A3 (en) 1999-10-27
HU9800901D0 (en) 1998-07-28
AU6198298A (en) 1998-10-22
TW490469B (en) 2002-06-11
ATE342921T1 (de) 2006-11-15
IL124123A (en) 2006-07-05
ES2273380T3 (es) 2007-05-01
CZ295049B6 (cs) 2005-05-18
PL325862A1 (en) 1998-10-26
DE69836164T2 (de) 2007-08-16

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