HUP9600876A3 - Benzonitril- and -fluoride derivatives, pharmaceutical compositions containing them, process for producing them and their use - Google Patents
Benzonitril- and -fluoride derivatives, pharmaceutical compositions containing them, process for producing them and their useInfo
- Publication number
- HUP9600876A3 HUP9600876A3 HU9600876A HUP9600876A HUP9600876A3 HU P9600876 A3 HUP9600876 A3 HU P9600876A3 HU 9600876 A HU9600876 A HU 9600876A HU P9600876 A HUP9600876 A HU P9600876A HU P9600876 A3 HUP9600876 A3 HU P9600876A3
- Authority
- HU
- Hungary
- Prior art keywords
- benzonitril
- producing
- pharmaceutical compositions
- compositions containing
- fluoride derivatives
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19512639A DE19512639A1 (de) | 1995-04-05 | 1995-04-05 | Benzonitrile und -fluoride |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU9600876D0 HU9600876D0 (en) | 1996-05-28 |
| HUP9600876A2 HUP9600876A2 (hu) | 1998-09-28 |
| HUP9600876A3 true HUP9600876A3 (en) | 2000-04-28 |
Family
ID=7758788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9600876A HUP9600876A3 (en) | 1995-04-05 | 1996-04-04 | Benzonitril- and -fluoride derivatives, pharmaceutical compositions containing them, process for producing them and their use |
Country Status (28)
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR004229A1 (es) * | 1995-11-06 | 1998-11-04 | Wyeth Corp | Derivados indolalquilo de benzodioxanmetilamina y su uso para preparar medicamentos |
| US7189753B1 (en) | 1997-11-06 | 2007-03-13 | Cady Roger K | Preemptive prophylaxis of migraine |
| US7517880B2 (en) | 1997-12-22 | 2009-04-14 | Bayer Pharmaceuticals Corporation | Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas |
| DK1147083T3 (da) * | 1999-01-07 | 2004-08-16 | Wyeth Corp | Arylpiperazinyl-cyclohexylindolderivater til behandling af depression |
| EP2298311B1 (en) * | 1999-01-13 | 2012-05-09 | Bayer HealthCare LLC | w-Carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors |
| US7351834B1 (en) | 1999-01-13 | 2008-04-01 | Bayer Pharmaceuticals Corporation | ω-Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| EP1140840B1 (en) * | 1999-01-13 | 2006-03-22 | Bayer Pharmaceuticals Corp. | -g(v)-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| US8124630B2 (en) | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| PL204331B1 (pl) * | 2000-11-14 | 2010-01-29 | Merck Patent Gmbh | Zastosowanie związków będących kombinowanymi selektywnymi inhibitorami wychwytu zwrotnego serotoniny (5-HT)(SSRIs) i agonistami receptora 5-HT1A do wytwarzania leków weterynaryjnych |
| UA76130C2 (en) * | 2000-11-20 | 2006-07-17 | Merck Patent Gmbh | Use of compounds combining properties of selective inhibitors of serotonin re-uptake and agonists of 5-ht1a receptor for treatment of irritable bowel syndrome |
| AR035521A1 (es) * | 2000-12-22 | 2004-06-02 | Lundbeck & Co As H | Derivados de 3-indolina y composicion farmaceutica que los comprende |
| US7371763B2 (en) * | 2001-04-20 | 2008-05-13 | Bayer Pharmaceuticals Corporation | Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas |
| ES2400070T3 (es) * | 2001-12-03 | 2013-04-05 | Bayer Healthcare Llc | Compuestos de aril-urea en combinación con otros agentes citostáticos o citotóxicos para tratamiento de cánceres humanos |
| US20030207872A1 (en) * | 2002-01-11 | 2003-11-06 | Bayer Corporation | Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| PT1478358E (pt) | 2002-02-11 | 2013-09-11 | Bayer Healthcare Llc | Tosilato de sorafenib para o tratamento de doenças caracterizadas por angiogénese anormal |
| AU2003209119A1 (en) | 2002-02-11 | 2003-09-04 | Bayer Pharmaceuticals Corporation | Pyridine, quinoline, and isoquinoline n-oxides as kinase inhibitors |
| UY28213A1 (es) | 2003-02-28 | 2004-09-30 | Bayer Pharmaceuticals Corp | Nuevos derivados de cianopiridina útiles en el tratamiento de cáncer y otros trastornos. |
| ATE366108T1 (de) | 2003-05-20 | 2007-07-15 | Bayer Pharmaceuticals Corp | Diaryl-harnstoffe für durch pdgfr vermittelte krankheiten |
| DK1663978T3 (da) | 2003-07-23 | 2008-04-07 | Bayer Pharmaceuticals Corp | Fluorsubstitueret omega-carboxyaryl-diphenylurinstof til behandling og forebyggelse af sygdomme og lidelser |
| TWI367098B (en) * | 2004-12-23 | 2012-07-01 | Kowa Co | Treating agent for glaucoma |
| CN102875538A (zh) * | 2012-10-16 | 2013-01-16 | 北京诚创思达医药科技有限公司 | 维拉唑酮或其盐酸盐的制备方法 |
| EP3027607B1 (en) | 2013-07-29 | 2020-08-26 | Sunshine Lake Pharma Co., Ltd. | Substituted heteroaryl compounds and methods of use thereof |
| CN104725359B (zh) | 2013-12-20 | 2017-05-03 | 广东东阳光药业有限公司 | 取代的哌嗪化合物及其使用方法和用途 |
| WO2016192657A1 (en) | 2015-06-03 | 2016-12-08 | Sunshine Lake Pharma Co., Ltd. | Substituted piperazine compounds and methods of use and use thereof |
| CN109574993B (zh) | 2017-09-29 | 2020-12-18 | 广东东阳光药业有限公司 | 取代的嘧啶哌嗪化合物及其用途 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1075156A (en) | 1963-08-27 | 1967-07-12 | Luso Farmaco Inst | Substituted piperazines |
| US3468882A (en) | 1966-10-07 | 1969-09-23 | Sterling Drug Inc | Phenylhydrazone derivatives as intermediates for preparing indoles |
| DE2138865A1 (de) | 1970-08-15 | 1973-02-22 | Sumitomo Chemical Co | 3-indolylpiperazine, verfahren zu ihrer herstellung und arzneimittel |
| GB8830312D0 (en) | 1988-12-28 | 1989-02-22 | Lundbeck & Co As H | Heterocyclic compounds |
| DE3923045A1 (de) * | 1989-07-13 | 1991-01-17 | Merck Patent Gmbh | Indolderivate |
| DE4101686A1 (de) * | 1991-01-22 | 1992-07-23 | Merck Patent Gmbh | Indolderivate |
| TW226019B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1992-03-23 | 1994-07-01 | Sankyo Co |
-
1995
- 1995-04-05 DE DE19512639A patent/DE19512639A1/de not_active Withdrawn
-
1996
- 1996-03-13 TW TW085103014A patent/TW323279B/zh active
- 1996-03-27 SK SK403-96A patent/SK281457B6/sk unknown
- 1996-03-28 ES ES96104955T patent/ES2150039T3/es not_active Expired - Lifetime
- 1996-03-28 PT PT96104955T patent/PT736525E/pt unknown
- 1996-03-28 DK DK96104955T patent/DK0736525T3/da active
- 1996-03-28 AT AT96104955T patent/ATE194595T1/de not_active IP Right Cessation
- 1996-03-28 DE DE59605568T patent/DE59605568D1/de not_active Expired - Fee Related
- 1996-03-28 SI SI9630240T patent/SI0736525T1/xx unknown
- 1996-03-28 EP EP96104955A patent/EP0736525B1/de not_active Expired - Lifetime
- 1996-03-29 AU AU50408/96A patent/AU709708B2/en not_active Ceased
- 1996-04-02 NO NO961346A patent/NO305903B1/no not_active IP Right Cessation
- 1996-04-02 CZ CZ1996964A patent/CZ289449B6/cs not_active IP Right Cessation
- 1996-04-03 CA CA002173418A patent/CA2173418C/en not_active Expired - Fee Related
- 1996-04-03 UA UA96041301A patent/UA45325C2/uk unknown
- 1996-04-03 AR AR10204696A patent/AR002982A1/es active IP Right Grant
- 1996-04-03 CO CO96016455A patent/CO4700469A1/es unknown
- 1996-04-03 RU RU96106426/04A patent/RU2168508C2/ru not_active IP Right Cessation
- 1996-04-04 TR TR96/00286A patent/TR199600286A2/xx unknown
- 1996-04-04 PL PL96313632A patent/PL183147B1/pl not_active IP Right Cessation
- 1996-04-04 ZA ZA962768A patent/ZA962768B/xx unknown
- 1996-04-04 HU HU9600876A patent/HUP9600876A3/hu unknown
- 1996-04-04 KR KR1019960010119A patent/KR100437751B1/ko not_active Expired - Fee Related
- 1996-04-04 BR BR9601275A patent/BR9601275A/pt not_active Application Discontinuation
- 1996-04-04 CN CN96100544A patent/CN1072209C/zh not_active Expired - Fee Related
- 1996-04-05 US US08/628,250 patent/US6310068B1/en not_active Expired - Fee Related
- 1996-04-05 JP JP10871996A patent/JP3834098B2/ja not_active Expired - Fee Related
-
2000
- 2000-09-29 GR GR20000402204T patent/GR3034514T3/el not_active IP Right Cessation
-
2001
- 2001-10-12 CY CY0100031A patent/CY2242B1/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |