BR9601275A - Compostos processo para sua preparação medicamentos preparação farmacêutica processo para sua produção e uso - Google Patents

Compostos processo para sua preparação medicamentos preparação farmacêutica processo para sua produção e uso

Info

Publication number
BR9601275A
BR9601275A BR9601275A BR9601275A BR9601275A BR 9601275 A BR9601275 A BR 9601275A BR 9601275 A BR9601275 A BR 9601275A BR 9601275 A BR9601275 A BR 9601275A BR 9601275 A BR9601275 A BR 9601275A
Authority
BR
Brazil
Prior art keywords
preparation
production
compounds
pharmaceutical preparation
medicines pharmaceutical
Prior art date
Application number
BR9601275A
Other languages
English (en)
Inventor
Henning Boettcher
Karl Ulrich Buehring
Hartmut Greiner
Rd Bartoszyk
Christoph Seyfried
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of BR9601275A publication Critical patent/BR9601275A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
BR9601275A 1995-04-05 1996-04-04 Compostos processo para sua preparação medicamentos preparação farmacêutica processo para sua produção e uso BR9601275A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19512639A DE19512639A1 (de) 1995-04-05 1995-04-05 Benzonitrile und -fluoride

Publications (1)

Publication Number Publication Date
BR9601275A true BR9601275A (pt) 1998-01-13

Family

ID=7758788

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9601275A BR9601275A (pt) 1995-04-05 1996-04-04 Compostos processo para sua preparação medicamentos preparação farmacêutica processo para sua produção e uso

Country Status (28)

Country Link
US (1) US6310068B1 (pt)
EP (1) EP0736525B1 (pt)
JP (1) JP3834098B2 (pt)
KR (1) KR100437751B1 (pt)
CN (1) CN1072209C (pt)
AR (1) AR002982A1 (pt)
AT (1) ATE194595T1 (pt)
AU (1) AU709708B2 (pt)
BR (1) BR9601275A (pt)
CA (1) CA2173418C (pt)
CO (1) CO4700469A1 (pt)
CY (1) CY2242B1 (pt)
CZ (1) CZ289449B6 (pt)
DE (2) DE19512639A1 (pt)
DK (1) DK0736525T3 (pt)
ES (1) ES2150039T3 (pt)
GR (1) GR3034514T3 (pt)
HU (1) HUP9600876A3 (pt)
NO (1) NO305903B1 (pt)
PL (1) PL183147B1 (pt)
PT (1) PT736525E (pt)
RU (1) RU2168508C2 (pt)
SI (1) SI0736525T1 (pt)
SK (1) SK281457B6 (pt)
TR (1) TR199600286A2 (pt)
TW (1) TW323279B (pt)
UA (1) UA45325C2 (pt)
ZA (1) ZA962768B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR004229A1 (es) * 1995-11-06 1998-11-04 Wyeth Corp Derivados indolalquilo de benzodioxanmetilamina y su uso para preparar medicamentos
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
DK1147083T3 (da) * 1999-01-07 2004-08-16 Wyeth Corp Arylpiperazinyl-cyclohexylindolderivater til behandling af depression
CA2359244C (en) 1999-01-13 2013-10-08 Bayer Corporation .omega.-carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors
EP1140840B1 (en) * 1999-01-13 2006-03-22 Bayer Pharmaceuticals Corp. -g(v)-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
HUP0302751A3 (en) * 2000-11-14 2007-06-28 Merck Patent Gmbh Novel uses of combined 5-ht1a agonists and serotonin reuptake inhibitors
UA76130C2 (en) 2000-11-20 2006-07-17 Merck Patent Gmbh Use of compounds combining properties of selective inhibitors of serotonin re-uptake and agonists of 5-ht1a receptor for treatment of irritable bowel syndrome
AR035521A1 (es) * 2000-12-22 2004-06-02 Lundbeck & Co As H Derivados de 3-indolina y composicion farmaceutica que los comprende
US7371763B2 (en) * 2001-04-20 2008-05-13 Bayer Pharmaceuticals Corporation Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
ES2275931T5 (es) * 2001-12-03 2018-10-23 Bayer Healthcare Llc Compuestos de aril-urea en combinación con otros agentes citostáticos o citotóxicos para tratamiento de cánceres humanos
US20030207872A1 (en) * 2002-01-11 2003-11-06 Bayer Corporation Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
DK1478358T3 (da) 2002-02-11 2013-10-07 Bayer Healthcare Llc Sorafenibtosylat til behandling af sygdomme kendetegnet ved unormal angiogenese
WO2003068229A1 (en) 2002-02-11 2003-08-21 Bayer Pharmaceuticals Corporation Pyridine, quinoline, and isoquinoline n-oxides as kinase inhibitors
UY28213A1 (es) 2003-02-28 2004-09-30 Bayer Pharmaceuticals Corp Nuevos derivados de cianopiridina útiles en el tratamiento de cáncer y otros trastornos.
PT1626714E (pt) 2003-05-20 2007-08-24 Bayer Pharmaceuticals Corp Diarilureias para doenças mediadas por pdgfr
ES2297490T3 (es) 2003-07-23 2008-05-01 Bayer Pharmaceuticals Corporation Omega-carboxiarildifenilurea fluoro sustituida para el tratamiento y prevencion de enfermadades y afecciones.
TWI367098B (en) * 2004-12-23 2012-07-01 Kowa Co Treating agent for glaucoma
CN102875538A (zh) * 2012-10-16 2013-01-16 北京诚创思达医药科技有限公司 维拉唑酮或其盐酸盐的制备方法
EP3027607B1 (en) 2013-07-29 2020-08-26 Sunshine Lake Pharma Co., Ltd. Substituted heteroaryl compounds and methods of use thereof
CN104725359B (zh) 2013-12-20 2017-05-03 广东东阳光药业有限公司 取代的哌嗪化合物及其使用方法和用途
US10316025B2 (en) 2015-06-03 2019-06-11 Sunshine Lake Pharma Co., Ltd. Substituted piperazine compounds and methods of use and use thereof
ES2974248T3 (es) 2017-09-29 2024-06-26 Sunshine Lake Pharma Co Ltd Compuesto de pirimidin-piperazina sustituido y uso del mismo

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1075156A (en) 1963-08-27 1967-07-12 Luso Farmaco Inst Substituted piperazines
US3468882A (en) 1966-10-07 1969-09-23 Sterling Drug Inc Phenylhydrazone derivatives as intermediates for preparing indoles
DE2138865A1 (de) 1970-08-15 1973-02-22 Sumitomo Chemical Co 3-indolylpiperazine, verfahren zu ihrer herstellung und arzneimittel
GB8830312D0 (en) 1988-12-28 1989-02-22 Lundbeck & Co As H Heterocyclic compounds
DE4101686A1 (de) * 1991-01-22 1992-07-23 Merck Patent Gmbh Indolderivate

Also Published As

Publication number Publication date
HUP9600876A3 (en) 2000-04-28
DE59605568D1 (de) 2000-08-17
UA45325C2 (uk) 2002-04-15
TW323279B (pt) 1997-12-21
DE19512639A1 (de) 1996-10-10
PT736525E (pt) 2000-12-29
TR199600286A2 (tr) 1997-03-21
US6310068B1 (en) 2001-10-30
NO961346D0 (no) 1996-04-02
KR960037675A (ko) 1996-11-19
CN1072209C (zh) 2001-10-03
CO4700469A1 (es) 1998-12-29
HUP9600876A2 (hu) 1998-09-28
SK281457B6 (sk) 2001-03-12
JPH09151174A (ja) 1997-06-10
NO305903B1 (no) 1999-08-16
AR002982A1 (es) 1998-05-27
CN1137036A (zh) 1996-12-04
PL183147B1 (pl) 2002-05-31
AU5040896A (en) 1996-10-17
EP0736525A1 (de) 1996-10-09
GR3034514T3 (en) 2000-12-29
ES2150039T3 (es) 2000-11-16
CA2173418A1 (en) 1996-10-06
NO961346L (no) 1996-10-07
PL313632A1 (en) 1996-10-14
JP3834098B2 (ja) 2006-10-18
DK0736525T3 (da) 2000-10-30
CY2242B1 (en) 2003-07-04
SK40396A3 (en) 1996-11-06
HU9600876D0 (en) 1996-05-28
ZA962768B (en) 1996-11-13
ATE194595T1 (de) 2000-07-15
RU2168508C2 (ru) 2001-06-10
CZ96496A3 (en) 1996-10-16
SI0736525T1 (en) 2001-02-28
CZ289449B6 (cs) 2002-01-16
CA2173418C (en) 2007-06-12
KR100437751B1 (ko) 2004-08-25
AU709708B2 (en) 1999-09-02
EP0736525B1 (de) 2000-07-12

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Legal Events

Date Code Title Description
FB34 Technical and formal requirements: requirement - article 34 of industrial property law
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DE INT. CL. 7 C07D295/04, A61K 31/495

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFERIMENTO DO PRESENTE PEDIDO COM BASE NOS ARTIGOS 8O E 13O DA LPI, LEI NO 9.279 DE 14/05/1996.