HUP0203722A3 - Substituted phenyl-piperazine derivatives, pharmaceutical compositions containing them and their use - Google Patents
Substituted phenyl-piperazine derivatives, pharmaceutical compositions containing them and their useInfo
- Publication number
- HUP0203722A3 HUP0203722A3 HU0203722A HUP0203722A HUP0203722A3 HU P0203722 A3 HUP0203722 A3 HU P0203722A3 HU 0203722 A HU0203722 A HU 0203722A HU P0203722 A HUP0203722 A HU P0203722A HU P0203722 A3 HUP0203722 A3 HU P0203722A3
- Authority
- HU
- Hungary
- Prior art keywords
- pharmaceutical compositions
- substituted phenyl
- compositions containing
- piperazine derivatives
- piperazine
- Prior art date
Links
- 239000008194 pharmaceutical composition Chemical class 0.000 title 1
- YZTJYBJCZXZGCT-UHFFFAOYSA-N phenylpiperazine Chemical class C1CNCCN1C1=CC=CC=C1 YZTJYBJCZXZGCT-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA199901885 | 1999-12-30 | ||
| PCT/DK2000/000721 WO2001049678A1 (en) | 1999-12-30 | 2000-12-20 | Substituted phenyl-piperazine derivatives, their preparation and use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0203722A2 HUP0203722A2 (hu) | 2003-03-28 |
| HUP0203722A3 true HUP0203722A3 (en) | 2005-03-29 |
Family
ID=8108803
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0203722A HUP0203722A3 (en) | 1999-12-30 | 2000-12-20 | Substituted phenyl-piperazine derivatives, pharmaceutical compositions containing them and their use |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6699864B2 (hu) |
| EP (1) | EP1246816B1 (hu) |
| JP (1) | JP2003519224A (hu) |
| KR (1) | KR100790916B1 (hu) |
| CN (1) | CN1230432C (hu) |
| AR (1) | AR029428A1 (hu) |
| AT (1) | ATE261959T1 (hu) |
| AU (1) | AU2152101A (hu) |
| BG (1) | BG65262B1 (hu) |
| BR (1) | BR0016952A (hu) |
| CA (1) | CA2395705C (hu) |
| CZ (1) | CZ20022319A3 (hu) |
| DE (1) | DE60009155T2 (hu) |
| EA (1) | EA006071B1 (hu) |
| ES (1) | ES2213634T3 (hu) |
| HU (1) | HUP0203722A3 (hu) |
| IL (2) | IL150241A0 (hu) |
| IS (1) | IS2174B (hu) |
| MX (1) | MXPA02006223A (hu) |
| NO (1) | NO322666B1 (hu) |
| NZ (1) | NZ519647A (hu) |
| PL (1) | PL199351B1 (hu) |
| PT (1) | PT1246816E (hu) |
| SK (1) | SK9442002A3 (hu) |
| TR (2) | TR200400645T4 (hu) |
| UA (1) | UA72948C2 (hu) |
| WO (1) | WO2001049678A1 (hu) |
| ZA (1) | ZA200204814B (hu) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA81749C2 (uk) | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
| DE10259244A1 (de) * | 2002-12-17 | 2004-07-01 | Merck Patent Gmbh | N-(Indolethyl-)cycloamin-Verbindungen |
| UA81300C2 (en) * | 2003-04-04 | 2007-12-25 | Lundbeck & Co As H | Derivates of 4-(2-fenilsulfanilfenil)-1,2,3,6-tetrahydropiridin as retarding agents of serotonin recapture |
| AU2004226838B8 (en) | 2003-04-04 | 2009-06-11 | H. Lundbeck A/S | 4-(2-phenylsulfanyl-phenyl)-piperidine derivatives as serotonin reuptake inhibitors |
| MXPA06007172A (es) | 2003-12-23 | 2006-08-23 | Lundbeck & Co As H | Derivados de 2-(1h-indolilsulfanil)-bencilamina como ssri. |
| SE0400441D0 (sv) | 2004-02-25 | 2004-02-25 | Active Biotech Ab | Novel Benzofurans and Indols |
| AR052308A1 (es) | 2004-07-16 | 2007-03-14 | Lundbeck & Co As H | Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto |
| AR054393A1 (es) | 2005-06-17 | 2007-06-20 | Lundbeck & Co As H | Derivados de benzo(b)furano y benzo(b)tiofeno, composiciones farmaceuticas que los contienen y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por la inhibicion de la reabsorcion de neurotransmisores de amina biogenicos. |
| US7629473B2 (en) | 2005-06-17 | 2009-12-08 | H. Lundbeck A/S | 2-(1H-indolylsulfanyl)-aryl amine derivatives |
| EP2044043B2 (en) | 2006-06-16 | 2021-03-03 | H. Lundbeck A/S | 1- ý[- (2, 4-dimethylphenylsulfanyl) -phenyl]piperazine hydrobromide as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment |
| AU2008310883A1 (en) * | 2007-10-09 | 2009-04-16 | Hamann, Mark T | Method to use compositions having antidepressant anxiolytic and other neurological activity and compositions of matter |
| CA2718138A1 (en) * | 2008-03-14 | 2009-09-17 | Timo Heinrich | Azaindole compounds for treatment of central nervous system disorders |
| CN105283442B (zh) * | 2013-04-04 | 2018-04-13 | 斯洛文尼亚莱柯制药股份有限公司 | 用于合成1‑(2‑((2,4‑二甲基苯基)硫代)苯基)哌嗪的方法 |
| WO2015169180A1 (en) * | 2014-05-04 | 2015-11-12 | Sunshine Lake Pharma Co., Ltd. | Substituted piperazine compounds and methods and use thereof |
| CN105085491B (zh) * | 2014-05-05 | 2019-06-25 | 广东东阳光药业有限公司 | 取代的吲哚化合物及其使用方法和用途 |
| US10316025B2 (en) | 2015-06-03 | 2019-06-11 | Sunshine Lake Pharma Co., Ltd. | Substituted piperazine compounds and methods of use and use thereof |
| WO2017012579A1 (zh) * | 2015-07-23 | 2017-01-26 | 广东东阳光药业有限公司 | 取代的吲哚化合物及其使用方法和用途 |
| US11285153B2 (en) | 2017-09-29 | 2022-03-29 | Sunshine Lake Pharma Co., Ltd. | Substituted pyrimidine piperazine compound and use thereof |
| CN111518012A (zh) * | 2020-05-27 | 2020-08-11 | 中国药科大学 | 含苯硫醚结构的化合物或其药学上可接受的盐、制备方法和用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2138865A1 (de) * | 1970-08-15 | 1973-02-22 | Sumitomo Chemical Co | 3-indolylpiperazine, verfahren zu ihrer herstellung und arzneimittel |
| GB8830312D0 (en) * | 1988-12-28 | 1989-02-22 | Lundbeck & Co As H | Heterocyclic compounds |
| WO1994024105A1 (en) * | 1993-04-15 | 1994-10-27 | Merck Sharp & Dohme Limited | Indole derivatives as dopamine d4 antagonists |
| FR2712591B1 (fr) | 1993-11-19 | 1996-02-09 | Pf Medicament | Nouvelles arylpipérazines dérivées d'indole, leur préparation et leur utilisation thérapeutique. |
| WO1997019039A1 (en) | 1995-11-17 | 1997-05-29 | Novartis Ag | Solid phase synthesis of heterocyclic compounds and combinatorial compound library |
| USH2007H1 (en) * | 1996-01-19 | 2001-12-04 | Fmc Corporation | Insecticidal N-heterocyclylalkyl-or N-[(polycyclyl)alkyl]-N′substituted piperazines |
| ES2128266B1 (es) * | 1997-07-08 | 2000-01-16 | Vita Invest Sa | Compuestos derivados de tiofeno y benzotiofeno y utilizacion y composicion correspondientes. |
| WO2000077519A1 (en) | 1999-06-15 | 2000-12-21 | Aventis Pharmaceuticals Products Inc. | Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives |
| EP1246819A1 (en) * | 1999-12-30 | 2002-10-09 | H. Lundbeck A/S | A method for the preparation of substituted benzene derivatives |
-
2000
- 2000-12-20 KR KR1020027008608A patent/KR100790916B1/ko not_active IP Right Cessation
- 2000-12-20 CN CNB008192057A patent/CN1230432C/zh not_active Expired - Fee Related
- 2000-12-20 UA UA2002065260A patent/UA72948C2/uk unknown
- 2000-12-20 SK SK944-2002A patent/SK9442002A3/sk unknown
- 2000-12-20 BR BR0016952-8A patent/BR0016952A/pt not_active Application Discontinuation
- 2000-12-20 CA CA002395705A patent/CA2395705C/en not_active Expired - Fee Related
- 2000-12-20 PT PT00984924T patent/PT1246816E/pt unknown
- 2000-12-20 AT AT00984924T patent/ATE261959T1/de not_active IP Right Cessation
- 2000-12-20 PL PL355539A patent/PL199351B1/pl not_active IP Right Cessation
- 2000-12-20 TR TR2004/00645T patent/TR200400645T4/xx unknown
- 2000-12-20 EP EP00984924A patent/EP1246816B1/en not_active Expired - Lifetime
- 2000-12-20 AU AU21521/01A patent/AU2152101A/en not_active Abandoned
- 2000-12-20 WO PCT/DK2000/000721 patent/WO2001049678A1/en active IP Right Grant
- 2000-12-20 JP JP2001550218A patent/JP2003519224A/ja active Pending
- 2000-12-20 DE DE60009155T patent/DE60009155T2/de not_active Expired - Fee Related
- 2000-12-20 TR TR2002/01683T patent/TR200201683T2/xx unknown
- 2000-12-20 ES ES00984924T patent/ES2213634T3/es not_active Expired - Lifetime
- 2000-12-20 CZ CZ20022319A patent/CZ20022319A3/cs unknown
- 2000-12-20 HU HU0203722A patent/HUP0203722A3/hu unknown
- 2000-12-20 NZ NZ519647A patent/NZ519647A/en unknown
- 2000-12-20 MX MXPA02006223A patent/MXPA02006223A/es active IP Right Grant
- 2000-12-20 EA EA200200732A patent/EA006071B1/ru not_active IP Right Cessation
- 2000-12-20 IL IL15024100A patent/IL150241A0/xx unknown
- 2000-12-28 AR ARP000106987A patent/AR029428A1/es unknown
-
2002
- 2002-06-13 IS IS6420A patent/IS2174B/is unknown
- 2002-06-14 ZA ZA200204814A patent/ZA200204814B/xx unknown
- 2002-06-16 IL IL150241A patent/IL150241A/en not_active IP Right Cessation
- 2002-06-20 US US10/177,261 patent/US6699864B2/en not_active Expired - Fee Related
- 2002-06-28 NO NO20023146A patent/NO322666B1/no not_active IP Right Cessation
- 2002-07-17 BG BG106930A patent/BG65262B1/bg unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUP0200714A3 (en) | Pharmaceutical compounds, pharmaceutical compositions containing them and their use | |
| HUP0203403A3 (en) | New imidazole derivatives, pharmaceutical compositions containing them and their use | |
| HUP0400837A3 (en) | 2-phenyl-thiazole derivatives, their use and pharmaceutical compositions containing them | |
| HUP0204474A3 (en) | 1h-imidazopyridine derivatives, pharmaceutical compositions containing them and their use | |
| HUP0204081A3 (en) | 4-pyrimidinyl-n-acyl-l-phenylalanines, pharmaceutical compositions containing them and their use | |
| HUP0401567A3 (en) | Novel 4,5-dyhydro-1h-pyrazole derivatives having cb1-antagonistic activity, their use and pharmaceutical compositions containing them | |
| HUP0302969A3 (en) | Npyy5 antagonists, pharmaceutical compositions containing them and their use | |
| HUP0105414A3 (en) | Pyrrolo-isoquinoline, azepino- and diazepino-indole derivatives, their use and pharmaceutical compisitions containing them | |
| HUP0400467A3 (en) | 2-iminopyrrolidine derivatives, pharmaceutical compositions containing them and their use | |
| HUP0301722A3 (en) | Pyrimidine derivatives, pharmaceutical compositions containing them and their use | |
| HUP0303069A3 (en) | Imidazole derivatives, pharmaceutical compositions containing them and their use | |
| HUP0202795A3 (en) | Pyrimidine and pyrazine derivatives, pharmaceutical compositions containing them and their use | |
| HUP0200308A2 (en) | Quinolinecarboxamides as antiviral agents, pharmaceutical compositions containing them and their use | |
| HUP0400540A3 (en) | 2-pyrazolin-5-one derivatives, their use and pharmaceutical compositions containing them | |
| HUP0301573A3 (en) | Substituted arylpyrazines, pharmaceutical compositions containing them and their use | |
| HUP0200155A3 (en) | Thioamide derivatives, pharmaceutical compositions containing them and their use | |
| HUP0303082A3 (en) | Substituted indoleoxoacetic piperazine derivatives, pharmaceutical compositions containing them and their antiviral use | |
| HUP0102766A3 (en) | Aminomethylcarboxylic acid derivatives, their pharmaceutical use and pharmaceutical compositions comprising them | |
| HUP0200996A3 (en) | Amine derivatives, pharmaceutical compositions containing them and their use | |
| HUP0203194A3 (en) | Phenylpiperazines, pharmaceutical compositions containing them and their use | |
| HUP0203735A3 (en) | 4-pyridinyl-n-acyl-l-phenylalanines, pharmaceutical compositions containing them and their use | |
| HUP0203722A3 (en) | Substituted phenyl-piperazine derivatives, pharmaceutical compositions containing them and their use | |
| HUP0105073A3 (en) | 2-aminopyridine derivatives, their use as medicines and pharmaceutical compositions containing them | |
| HUP0400967A3 (en) | Substituted 2-anilino-benzimidazoles, their use and pharmaceutical compositions containing them | |
| HUP0202075A3 (en) | Substituted 2-dialkylaminoalkylbiphenyl derivatives, process for their preparation, pharmaceutical compositions containing them and their use |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |