HUP0200843A2 - Eljárás vízben oldhatatlan, amorf vagy részben amorf, szabályozottan felszabaduló mátrix előállítására - Google Patents

Eljárás vízben oldhatatlan, amorf vagy részben amorf, szabályozottan felszabaduló mátrix előállítására

Info

Publication number
HUP0200843A2
HUP0200843A2 HU0200843A HUP0200843A HUP0200843A2 HU P0200843 A2 HUP0200843 A2 HU P0200843A2 HU 0200843 A HU0200843 A HU 0200843A HU P0200843 A HUP0200843 A HU P0200843A HU P0200843 A2 HUP0200843 A2 HU P0200843A2
Authority
HU
Hungary
Prior art keywords
amorphous
producing
water
controlled release
release matrix
Prior art date
Application number
HU0200843A
Other languages
English (en)
Inventor
Hubert Rein
Klaus-Jürgen Steffens
Original Assignee
Euroceltique S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euroceltique S.A. filed Critical Euroceltique S.A.
Publication of HUP0200843A2 publication Critical patent/HUP0200843A2/hu
Publication of HUP0200843A3 publication Critical patent/HUP0200843A3/hu
Publication of HU227001B1 publication Critical patent/HU227001B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
HU0200843A 1999-04-22 2000-04-20 Method for producing a water-insoluble amorphous or partially amorphous controlled release matrix HU227001B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19918325A DE19918325A1 (de) 1999-04-22 1999-04-22 Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
PCT/EP2000/003612 WO2000064415A1 (de) 1999-04-22 2000-04-20 Verfahren zur herstellung einer wasserunlöslichen amorphen oder teilamorphen retardmatrix

Publications (3)

Publication Number Publication Date
HUP0200843A2 true HUP0200843A2 (hu) 2002-07-29
HUP0200843A3 HUP0200843A3 (en) 2003-04-28
HU227001B1 HU227001B1 (en) 2010-04-28

Family

ID=7905525

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0200843A HU227001B1 (en) 1999-04-22 2000-04-20 Method for producing a water-insoluble amorphous or partially amorphous controlled release matrix

Country Status (18)

Country Link
US (1) US8557286B1 (hu)
EP (2) EP1839651A1 (hu)
JP (2) JP4575599B2 (hu)
KR (1) KR100511113B1 (hu)
CN (1) CN1214783C (hu)
AT (1) ATE356617T1 (hu)
AU (1) AU763609B2 (hu)
BR (1) BR0009927B1 (hu)
CA (1) CA2372025C (hu)
CY (1) CY1106478T1 (hu)
DE (3) DE19918325A1 (hu)
DK (1) DK1171101T3 (hu)
ES (1) ES2284495T3 (hu)
HU (1) HU227001B1 (hu)
IL (1) IL145755A0 (hu)
PT (1) PT1171101E (hu)
RU (1) RU2208436C2 (hu)
WO (1) WO2000064415A1 (hu)

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US6375957B1 (en) 1997-12-22 2002-04-23 Euro-Celtique, S.A. Opioid agonist/opioid antagonist/acetaminophen combinations
DE19918325A1 (de) * 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
CN1525851A (zh) 2001-05-11 2004-09-01 ������ҩ�����޹�˾ 抗滥用阿片样物质控释剂型
AU2002342755A1 (en) * 2001-09-26 2003-04-14 Klaus-Jurgen Steffens Method and device for producing granulates that comprise at least one pharmaceutical active substance
CN100411611C (zh) 2002-04-05 2008-08-20 欧洲凯尔蒂克公司 用于持续,不变且独立释放活性化合物的基质
EP1479381A1 (en) * 2003-05-19 2004-11-24 Euro-Celtique S.A. Pharmaceutical dosage form comprising a solid solution
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US8367105B2 (en) 2004-11-10 2013-02-05 Teva Pharmaceutical Industries, Ltd. Compressed solid dosage form manufacturing process well-suited for use with drugs of low aqueous solubility and compressed solid dosage forms made thereby
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DE102007028869A1 (de) 2007-06-22 2008-12-24 Ratiopharm Gmbh Verfahren zur Herstellung eines Arzneimittels enthaltend Tadalafil
NZ595663A (en) 2009-03-10 2013-11-29 Euro Celtique Sa Immediate release pharmaceutical compositions comprising oxycodone and naloxone
DE102011011889B4 (de) 2011-02-21 2015-11-05 Leistritz Extrusionstechnik Gmbh Vorrichtung und Verfahren zur kontinuierlichen Herstellung von biplan geschnittenen Formkörpern enthaltend wenigstens einen Füllstoff
DE102011015370A1 (de) * 2011-03-29 2012-10-04 Emodys Gmbh Matrix für eine orale Darreichungsform, Verfahren zu deren Herstellung sowie Verwendung derselben
MY175307A (en) * 2011-12-21 2020-06-18 Bayer Ip Gmbh Preparations comprising amorphous emodepside
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EP3459527B1 (en) 2017-09-20 2022-11-23 Tillotts Pharma Ag Method for preparing a solid dosage form comprising antibodies by wet granulation, extrusion and spheronization

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IL145755A0 (en) 2002-07-25
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CA2372025C (en) 2007-09-25
EP1839651A1 (de) 2007-10-03
DE19918325A1 (de) 2000-10-26
HUP0200843A3 (en) 2003-04-28
BR0009927A (pt) 2002-01-08
RU2208436C2 (ru) 2003-07-20
BR0009927B1 (pt) 2011-12-27
CN1214783C (zh) 2005-08-17
AU4554200A (en) 2000-11-10
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ES2284495T3 (es) 2007-11-16
AU763609B2 (en) 2003-07-31
EP1171101B1 (de) 2007-03-14
DE50014164D1 (de) 2007-04-26
WO2000064415A1 (de) 2000-11-02
US8557286B1 (en) 2013-10-15
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