DK1171101T3 - Fremgangsmåde til fremstilling af en vanduoplöselig amorf depotmatrix - Google Patents

Fremgangsmåde til fremstilling af en vanduoplöselig amorf depotmatrix

Info

Publication number
DK1171101T3
DK1171101T3 DK00927010T DK00927010T DK1171101T3 DK 1171101 T3 DK1171101 T3 DK 1171101T3 DK 00927010 T DK00927010 T DK 00927010T DK 00927010 T DK00927010 T DK 00927010T DK 1171101 T3 DK1171101 T3 DK 1171101T3
Authority
DK
Denmark
Prior art keywords
preparing
water
matrix
insoluble amorphous
depot matrix
Prior art date
Application number
DK00927010T
Other languages
English (en)
Inventor
Hubert Rein
Klaus-Juergen Steffens
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Application granted granted Critical
Publication of DK1171101T3 publication Critical patent/DK1171101T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK00927010T 1999-04-22 2000-04-20 Fremgangsmåde til fremstilling af en vanduoplöselig amorf depotmatrix DK1171101T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19918325A DE19918325A1 (de) 1999-04-22 1999-04-22 Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
PCT/EP2000/003612 WO2000064415A1 (de) 1999-04-22 2000-04-20 Verfahren zur herstellung einer wasserunlöslichen amorphen oder teilamorphen retardmatrix

Publications (1)

Publication Number Publication Date
DK1171101T3 true DK1171101T3 (da) 2007-07-16

Family

ID=7905525

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00927010T DK1171101T3 (da) 1999-04-22 2000-04-20 Fremgangsmåde til fremstilling af en vanduoplöselig amorf depotmatrix

Country Status (18)

Country Link
US (1) US8557286B1 (da)
EP (2) EP1839651A1 (da)
JP (2) JP4575599B2 (da)
KR (1) KR100511113B1 (da)
CN (1) CN1214783C (da)
AT (1) ATE356617T1 (da)
AU (1) AU763609B2 (da)
BR (1) BR0009927B1 (da)
CA (1) CA2372025C (da)
CY (1) CY1106478T1 (da)
DE (3) DE19918325A1 (da)
DK (1) DK1171101T3 (da)
ES (1) ES2284495T3 (da)
HU (1) HU227001B1 (da)
IL (1) IL145755A0 (da)
PT (1) PT1171101E (da)
RU (1) RU2208436C2 (da)
WO (1) WO2000064415A1 (da)

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RS50070B (sr) 1997-12-22 2009-01-22 Euro-Celtique S.A., Oralni dozni oblik sa kombinacijom opijatnog agonista i antagonista
US6375957B1 (en) 1997-12-22 2002-04-23 Euro-Celtique, S.A. Opioid agonist/opioid antagonist/acetaminophen combinations
DE19918325A1 (de) * 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
CN1525851A (zh) 2001-05-11 2004-09-01 ������ҩ�����޹�˾ 抗滥用阿片样物质控释剂型
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DK2425824T5 (da) 2002-04-05 2018-02-12 Mundipharma As Farmaceutisk præparat indeholdende oxycodon og naloxon
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EP1604666A1 (en) 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD)
EP1604667A1 (en) 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioids for the treatment of the restless leg syndrome
US8367105B2 (en) 2004-11-10 2013-02-05 Teva Pharmaceutical Industries, Ltd. Compressed solid dosage form manufacturing process well-suited for use with drugs of low aqueous solubility and compressed solid dosage forms made thereby
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DE102007028869A1 (de) 2007-06-22 2008-12-24 Ratiopharm Gmbh Verfahren zur Herstellung eines Arzneimittels enthaltend Tadalafil
WO2010103039A1 (en) 2009-03-10 2010-09-16 Euro-Celtique S.A. Immediate release pharmaceutical compositions comprising oxycodone and naloxone
DE102011011889B4 (de) 2011-02-21 2015-11-05 Leistritz Extrusionstechnik Gmbh Vorrichtung und Verfahren zur kontinuierlichen Herstellung von biplan geschnittenen Formkörpern enthaltend wenigstens einen Füllstoff
DE102011015370A1 (de) * 2011-03-29 2012-10-04 Emodys Gmbh Matrix für eine orale Darreichungsform, Verfahren zu deren Herstellung sowie Verwendung derselben
JP6185930B2 (ja) * 2011-12-21 2017-08-23 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ 非晶質エモデプシド含有製剤
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EP3459527B1 (en) 2017-09-20 2022-11-23 Tillotts Pharma Ag Method for preparing a solid dosage form comprising antibodies by wet granulation, extrusion and spheronization

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HU227001B1 (en) 2010-04-28
RU2001128233A (ru) 2004-02-27
DE19918325A1 (de) 2000-10-26
JP5022086B2 (ja) 2012-09-12
DE50014164D1 (de) 2007-04-26
KR100511113B1 (ko) 2005-08-31
ES2284495T3 (es) 2007-11-16
IL145755A0 (en) 2002-07-25
CA2372025C (en) 2007-09-25
HUP0200843A3 (en) 2003-04-28
BR0009927B1 (pt) 2011-12-27
AU763609B2 (en) 2003-07-31
CA2372025A1 (en) 2000-11-02
CN1214783C (zh) 2005-08-17
ATE356617T1 (de) 2007-04-15
JP4575599B2 (ja) 2010-11-04
WO2000064415A1 (de) 2000-11-02
KR20010112440A (ko) 2001-12-20
US8557286B1 (en) 2013-10-15
JP2002542276A (ja) 2002-12-10
EP1171101A1 (de) 2002-01-16
DE20022720U1 (de) 2002-02-28
EP1839651A1 (de) 2007-10-03
PT1171101E (pt) 2007-06-08
CN1347315A (zh) 2002-05-01
BR0009927A (pt) 2002-01-08
JP2007211019A (ja) 2007-08-23
RU2208436C2 (ru) 2003-07-20
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AU4554200A (en) 2000-11-10
CY1106478T1 (el) 2012-01-25

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