HUP0102117A2 - Imidazo[1,2-a]piridin-származékok és ezeket tartalmazó gyógyászati készítmények - Google Patents

Imidazo[1,2-a]piridin-származékok és ezeket tartalmazó gyógyászati készítmények Download PDF

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Publication number
HUP0102117A2
HUP0102117A2 HU0102117A HUP0102117A HUP0102117A2 HU P0102117 A2 HUP0102117 A2 HU P0102117A2 HU 0102117 A HU0102117 A HU 0102117A HU P0102117 A HUP0102117 A HU P0102117A HU P0102117 A2 HUP0102117 A2 HU P0102117A2
Authority
HU
Hungary
Prior art keywords
mmol
formula
compound
pyridine
starting
Prior art date
Application number
HU0102117A
Other languages
English (en)
Hungarian (hu)
Inventor
Jesus Ezquerra-Carrera
Joseph Michael Gruber
Chafiq Hamdouchi
Richard Elmer Holmes
Wayne Alfred Spitzer
Original Assignee
Eli Lilly And Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co. filed Critical Eli Lilly And Co.
Publication of HUP0102117A2 publication Critical patent/HUP0102117A2/hu

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
HU0102117A 1998-05-20 1998-05-20 Imidazo[1,2-a]piridin-származékok és ezeket tartalmazó gyógyászati készítmények HUP0102117A2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1998/010299 WO1999059587A1 (en) 1998-05-20 1998-05-20 Anti-viral compounds

Publications (1)

Publication Number Publication Date
HUP0102117A2 true HUP0102117A2 (hu) 2001-12-28

Family

ID=22267098

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102117A HUP0102117A2 (hu) 1998-05-20 1998-05-20 Imidazo[1,2-a]piridin-származékok és ezeket tartalmazó gyógyászati készítmények

Country Status (15)

Country Link
EP (1) EP1077701A4 (cs)
JP (1) JP2002515433A (cs)
KR (1) KR20010025055A (cs)
CN (1) CN1292697A (cs)
AU (1) AU7583098A (cs)
BR (1) BR9815899A (cs)
CA (1) CA2332403A1 (cs)
CZ (1) CZ289425B6 (cs)
EA (1) EA200001208A1 (cs)
HU (1) HUP0102117A2 (cs)
IL (1) IL139166A0 (cs)
NO (1) NO20005795L (cs)
SK (1) SK17482000A3 (cs)
TR (1) TR200003414T2 (cs)
WO (1) WO1999059587A1 (cs)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR213700A0 (en) * 2000-12-18 2001-01-25 Biota Scientific Management Pty Ltd Antiviral agents
AR048650A1 (es) * 2004-05-04 2006-05-10 Tibotec Pharm Ltd Derivados de (1,10b-dihidro-2-(aminocarbonil-fenil)-5h-pirazolo[1,5 c][1,3]benzoxazin-5-il)fenil metanona como inhibidores de la replicacion viral del vih
CA2576993C (en) 2004-08-12 2013-09-24 Amgen Inc. Bisaryl-sulfonamides
US7666880B2 (en) 2005-03-21 2010-02-23 S*Bio Pte Ltd. Imidazo[1,2-A]pyridine derivatives: preparation and pharmaceutical applications
MX2007011710A (es) * 2005-03-21 2007-11-20 S Bio Pte Ltd Derivados de imidazo[1,2-a]piridina, preparacion y aplicaciones farmaceuticas.
CA2633760A1 (en) 2005-12-21 2007-07-05 Abbott Laboratories Anti-viral compounds
US7915411B2 (en) 2005-12-21 2011-03-29 Abbott Laboratories Anti-viral compounds
EP1979348B1 (en) 2005-12-21 2012-01-18 Abbott Laboratories Anti-viral compounds
TWI399380B (zh) 2006-12-20 2013-06-21 Abbott Lab 抗病毒化合物
EP2297141B1 (en) * 2008-05-27 2015-10-21 Biota Scientific Management Pty Ltd Antiviral salts
EP2367824B1 (en) 2008-12-23 2016-03-23 AbbVie Inc. Anti-viral derivatives of pyrimidine
EP2367823A1 (en) 2008-12-23 2011-09-28 Abbott Laboratories Anti-viral compounds
EP2419404B1 (en) * 2009-04-15 2015-11-04 AbbVie Inc. Anti-viral compounds
WO2014060381A1 (de) 2012-10-18 2014-04-24 Bayer Cropscience Ag Heterocyclische verbindungen als schädlingsbekämpfungsmittel
WO2014067962A1 (de) 2012-10-31 2014-05-08 Bayer Cropscience Ag Neue heterocylische verbindungen als schädlingsbekämpfungsmittel
CN104370732B (zh) * 2014-01-26 2015-08-19 山东信立泰药业有限公司 一种氯吡格雷及其中间体的制备方法
CN109535405B (zh) * 2017-09-21 2021-07-30 宁波聚嘉新材料科技有限公司 一种基于2-(4-羧基苯基)-5-羟基吡啶并咪唑的聚芳酯的制备方法
CN109810085B (zh) * 2019-04-19 2019-07-19 上海皓元生物医药科技有限公司 Acc抑制剂及其中间体的制备方法
CN110746450A (zh) * 2019-09-17 2020-02-04 济南康和医药科技有限公司 一种贝前列素钠关键中间体的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4096264A (en) * 1975-12-09 1978-06-20 Merck & Co., Inc. Certain substituted imidazo [1,2-a] pyridines
US4250174A (en) * 1979-05-02 1981-02-10 Merck & Co., Inc. 3-Substituted imidazo [1,2-A] pyridines
US5693661A (en) * 1995-06-07 1997-12-02 Eli Lilly And Company Anti-viral compounds
US5891874A (en) * 1996-06-05 1999-04-06 Eli Lilly And Company Anti-viral compound
EA001316B1 (ru) * 1996-06-05 2001-02-26 Эли Лилли Энд Компании Соединения, обладающие антивирусной активностью
US5821242A (en) * 1996-06-06 1998-10-13 Eli Lilly And Company Anti-viral compounds

Also Published As

Publication number Publication date
EP1077701A4 (en) 2002-03-20
JP2002515433A (ja) 2002-05-28
EA200001208A1 (ru) 2001-06-25
KR20010025055A (ko) 2001-03-26
IL139166A0 (en) 2001-11-25
BR9815899A (pt) 2001-02-20
CZ289425B6 (cs) 2002-01-16
EP1077701A1 (en) 2001-02-28
CZ20004278A3 (en) 2001-05-16
CA2332403A1 (en) 1999-11-25
SK17482000A3 (sk) 2005-03-04
AU7583098A (en) 1999-12-06
NO20005795D0 (no) 2000-11-16
NO20005795L (no) 2001-01-18
TR200003414T2 (tr) 2001-03-21
WO1999059587A1 (en) 1999-11-25
CN1292697A (zh) 2001-04-25

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