ATE475660T1 - Antivirale verbindungen - Google Patents
Antivirale verbindungenInfo
- Publication number
- ATE475660T1 ATE475660T1 AT06848056T AT06848056T ATE475660T1 AT E475660 T1 ATE475660 T1 AT E475660T1 AT 06848056 T AT06848056 T AT 06848056T AT 06848056 T AT06848056 T AT 06848056T AT E475660 T1 ATE475660 T1 AT E475660T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- antiviral compounds
- hcv
- viral
- syntheses
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75247305P | 2005-12-21 | 2005-12-21 | |
US11/613,836 US7763731B2 (en) | 2005-12-21 | 2006-12-20 | Anti-viral compounds |
PCT/US2006/049080 WO2007076035A2 (en) | 2005-12-21 | 2006-12-20 | Anti-viral compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE475660T1 true ATE475660T1 (de) | 2010-08-15 |
Family
ID=38069383
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06848056T ATE475660T1 (de) | 2005-12-21 | 2006-12-20 | Antivirale verbindungen |
Country Status (10)
Country | Link |
---|---|
US (2) | US7763731B2 (de) |
EP (1) | EP1979349B1 (de) |
JP (1) | JP2009521480A (de) |
CN (1) | CN102702194A (de) |
AT (1) | ATE475660T1 (de) |
CA (1) | CA2633760A1 (de) |
DE (1) | DE602006015861D1 (de) |
HK (1) | HK1122292A1 (de) |
RU (1) | RU2467007C2 (de) |
WO (1) | WO2007076035A2 (de) |
Families Citing this family (42)
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DE602006015861D1 (de) | 2005-12-21 | 2010-09-09 | Abbott Lab | Antivirale verbindungen |
AU2006330924B2 (en) * | 2005-12-21 | 2012-03-15 | Abbvie Inc. | Anti-viral compounds |
ES2395386T3 (es) | 2005-12-21 | 2013-02-12 | Abbott Laboratories | Compuestos antivirales |
TWI399380B (zh) | 2006-12-20 | 2013-06-21 | Abbott Lab | 抗病毒化合物 |
WO2009089263A2 (en) * | 2008-01-07 | 2009-07-16 | Ardea Biosciences Inc. | Novel compositions and methods of use |
CA2728228A1 (en) | 2008-07-14 | 2010-01-21 | Gilead Sciences, Inc. | Oxindolyl inhibitor compounds |
CN102245604A (zh) * | 2008-12-23 | 2011-11-16 | 雅培制药有限公司 | 抗病毒化合物 |
JP2012513409A (ja) * | 2008-12-23 | 2012-06-14 | アボット・ラボラトリーズ | 抗ウイルス化合物 |
WO2010098866A1 (en) | 2009-02-27 | 2010-09-02 | Supergen, Inc. | Cyclopentathiophene/cyclohexathiophene dna methyltransferase inhibitors |
RU2541571C2 (ru) | 2009-04-15 | 2015-02-20 | Эббви Инк. | Противовирусные соединения |
CA2763786C (en) | 2009-06-08 | 2014-09-30 | Gilead Sciences, Inc. | Alkanoylamino benzamide aniline hdac inihibitor compounds |
ES2463826T3 (es) | 2009-06-08 | 2014-05-29 | Gilead Sciences, Inc. | Compuestos inhibidores de HDAC de cicloalquilcarbamato benzamida anilina |
US8716454B2 (en) | 2009-06-11 | 2014-05-06 | Abbvie Inc. | Solid compositions |
TWI469780B (zh) | 2009-06-11 | 2015-01-21 | Abbvie Bahamas Ltd | 抗病毒化合物 |
US9394279B2 (en) | 2009-06-11 | 2016-07-19 | Abbvie Inc. | Anti-viral compounds |
US8937150B2 (en) | 2009-06-11 | 2015-01-20 | Abbvie Inc. | Anti-viral compounds |
US20110137633A1 (en) * | 2009-12-03 | 2011-06-09 | Abbott Laboratories | Anti-viral compounds and methods of identifying the same |
NZ605440A (en) | 2010-06-10 | 2014-05-30 | Abbvie Bahamas Ltd | Solid compositions comprising an hcv inhibitor |
US8841275B2 (en) | 2010-11-30 | 2014-09-23 | Gilead Pharmasset Llc | 2′-spiro-nucleosides and derivatives thereof useful for treating hepatitis C virus and dengue virus infections |
US10201584B1 (en) | 2011-05-17 | 2019-02-12 | Abbvie Inc. | Compositions and methods for treating HCV |
DE202012013074U1 (de) | 2011-09-16 | 2014-10-29 | Gilead Pharmasset Lcc | Zusammensetzungen zur Behandlung von HCV |
US8889159B2 (en) | 2011-11-29 | 2014-11-18 | Gilead Pharmasset Llc | Compositions and methods for treating hepatitis C virus |
US9034832B2 (en) | 2011-12-29 | 2015-05-19 | Abbvie Inc. | Solid compositions |
CN106188045B (zh) * | 2012-06-15 | 2018-01-16 | 广州源生医药科技有限公司 | 作为wnt信号传导抑制剂的化合物、组合物及其应用 |
JP5922791B2 (ja) | 2012-10-29 | 2016-05-24 | 京セラ株式会社 | 弾性表面波センサ |
BR112015010620A2 (pt) | 2012-11-08 | 2017-07-11 | Pfizer | compostos heteroaromáticos e seus usos como ligantes de dopamina d1 |
SI2950786T1 (sl) | 2013-01-31 | 2020-03-31 | Gilead Pharmasset Llc | Formulacija kombinacije dveh protivirusnih spojin |
US11484534B2 (en) | 2013-03-14 | 2022-11-01 | Abbvie Inc. | Methods for treating HCV |
WO2015103490A1 (en) | 2014-01-03 | 2015-07-09 | Abbvie, Inc. | Solid antiviral dosage forms |
EP3134405B1 (de) | 2014-04-25 | 2019-08-28 | Pfizer Inc | Heteroaromatische verbindungen und deren verwendung als dopamin-d1-liganden |
CN104086543A (zh) * | 2014-06-19 | 2014-10-08 | 湖南华腾制药有限公司 | 一种制备4-氯-1,8-二氮萘的方法 |
BR112016029756B1 (pt) | 2014-06-27 | 2021-05-04 | Agro-Kanesho Co., Ltd | método para produzir um composto |
WO2016011195A1 (en) | 2014-07-17 | 2016-01-21 | Threshold Pharmaceuticals, Inc. | Th-302 solid forms and methods related thereto |
SG11201707293VA (en) * | 2015-03-10 | 2017-10-30 | Ascenta Pharmaceuticals Ltd | Dna alkylating agents |
EP3277381A4 (de) | 2015-04-02 | 2018-12-05 | Obi Pharma, Inc. | Nitrobenzylderivate von antikrebsmitteln |
WO2016210175A1 (en) | 2015-06-24 | 2016-12-29 | Threshold Pharmaceuticals, Inc. | Aziridine containing dna alkylating agents |
PL3325482T3 (pl) * | 2015-07-21 | 2021-01-11 | Immunogen, Inc. | Sposoby otrzymywania cytotoksycznych pochodnych benzodiazepiny |
BR112018006873A2 (pt) | 2015-10-05 | 2018-11-06 | The Trustees Of Columbia University In The City Of New York | ativadores do fluxo autofágico e fosfolipase d e depuração de agregados de proteína incluindo tau e tratamento de proteinopatias |
CN105461582A (zh) * | 2015-11-18 | 2016-04-06 | 浙江汇能生物股份有限公司 | 一种碘醚柳胺的制备方法 |
US10239875B2 (en) | 2017-06-16 | 2019-03-26 | King Saud University | Naphthyridinyl hydrazine derivatives as potent peripheral analgesic agents |
EP3594205A1 (de) | 2018-07-09 | 2020-01-15 | Abivax | Phenyl-n-aryl-derivate zur behandlung einer rna-virusinfektion |
EP3594206A1 (de) | 2018-07-09 | 2020-01-15 | Abivax | Phenyl-n-chinolin-derivate zur behandlung einer rna-virusinfektion |
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BR9710362A (pt) | 1996-07-13 | 1999-08-17 | Glaxo Group Ltd | Composto formula-ao farmaceutica utiliza-ao de um composto processos de tratamento de um ser humano ou animal sofrendo de uma mediada por atividade anormal de cinase de proteina tirosina e para a prepara-ao de um composto |
HRP970371A2 (en) | 1996-07-13 | 1998-08-31 | Kathryn Jane Smith | Heterocyclic compounds |
FR2751330B1 (fr) | 1996-07-16 | 1998-10-30 | Pernod Ricard | Procede de production de derivees de diol-1,3 naturels et de derives de 1,3-dioxane naturels correspondants |
ES2191183T3 (es) | 1996-08-06 | 2003-09-01 | Pfizer | Derivados 6,6- o 6,7-biciclicos que contienen pirido o pirimido sustituidos. |
TW477787B (en) | 1996-08-27 | 2002-03-01 | Pfizer | Pyrido six-membered nitrogen-containing cyclic ring derivatives having corticotropin releasing factor antagonist activity and pharmaceutical composition containing same |
US6809097B1 (en) * | 1996-09-25 | 2004-10-26 | Zeneca Limited | Quinoline derivatives inhibiting the effect of growth factors such as VEGF |
DE19647413A1 (de) | 1996-11-15 | 1998-05-20 | Hoechst Schering Agrevo Gmbh | Substituierte Stickstoff-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel |
DE19647317A1 (de) * | 1996-11-15 | 1998-05-20 | Hoechst Schering Agrevo Gmbh | Substituierte Stickstoff-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel |
WO1998023613A1 (en) * | 1996-11-27 | 1998-06-04 | Pfizer Inc. | Fused bicyclic pyrimidine derivatives |
DK1058686T3 (da) * | 1998-02-25 | 2007-03-05 | Univ Emory | 2'-fluornukleosider |
CZ289425B6 (cs) | 1998-05-20 | 2002-01-16 | Eli Lilly And Company | Imidazo[1,2-a] pyridinové sloučeniny, jejich pouľití a farmaceutický přípravek s jejich obsahem |
US6323180B1 (en) * | 1998-08-10 | 2001-11-27 | Boehringer Ingelheim (Canada) Ltd | Hepatitis C inhibitor tri-peptides |
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US6448281B1 (en) | 2000-07-06 | 2002-09-10 | Boehringer Ingelheim (Canada) Ltd. | Viral polymerase inhibitors |
US7622503B2 (en) * | 2000-08-24 | 2009-11-24 | University Of Tennessee Research Foundation | Selective androgen receptor modulators and methods of use thereof |
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US20040110785A1 (en) * | 2001-02-02 | 2004-06-10 | Tao Wang | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives |
WO2002089731A2 (en) * | 2001-05-03 | 2002-11-14 | Stanford University | Agents for treatment of hcv and methods of use |
US20030158195A1 (en) * | 2001-12-21 | 2003-08-21 | Cywin Charles L. | 1,6 naphthyridines useful as inhibitors of SYK kinase |
US7037913B2 (en) * | 2002-05-01 | 2006-05-02 | Bristol-Myers Squibb Company | Bicyclo 4.4.0 antiviral derivatives |
WO2004014852A2 (en) | 2002-08-12 | 2004-02-19 | Bristol-Myers Squibb Company | Iminothiazolidinones as inhibitors of hcv replication |
US7358249B2 (en) | 2002-08-13 | 2008-04-15 | Shionogi & Co., Ltd. | Heterocyclic compounds having inhibitory activity against HIV integrase |
US20050075331A1 (en) * | 2003-10-06 | 2005-04-07 | Pratt John K. | Anti-infective agents |
WO2004047818A2 (en) | 2002-11-22 | 2004-06-10 | Scios, Inc. | USE OF TFG-β INHIBITORSTO COUNTERACT PATHOLOGIC CHANGES IN THE LEVEL OR FUNCTION OF STEROID/THYROID RECEPTORS |
AU2003300898A1 (en) | 2002-12-13 | 2004-07-09 | Neurogen Corporation | Carboxylic acid, phosphate or phosphonate substituted quinazolin-4-ylamine analogues as capsaicin receptor modulators |
WO2004065392A1 (en) | 2003-01-24 | 2004-08-05 | Smithkline Beecham Corporation | Condensed pyridines and pyrimidines and their use as alk-5 receptor ligands |
JP2006521398A (ja) | 2003-03-28 | 2006-09-21 | サイオス・インコーポレーテツド | TGFβの二−環式ピリミジン阻害剤 |
WO2004106308A1 (en) * | 2003-05-27 | 2004-12-09 | Pfizer Products Inc. | Quinazolines and pyrido [3,4-d] pyrimidines as receptor tyrosine kinase inhibitors |
TW200510373A (en) * | 2003-07-14 | 2005-03-16 | Neurogen Corp | Substituted quinolin-4-ylamine analogues |
US7378414B2 (en) * | 2003-08-25 | 2008-05-27 | Abbott Laboratories | Anti-infective agents |
GB0326168D0 (en) * | 2003-11-10 | 2003-12-17 | Arrow Therapeutics Ltd | Chemical compounds |
JP2007534735A (ja) | 2004-04-28 | 2007-11-29 | アロウ セラピューティクス リミテッド | 抗ウイルス剤として使用するためのモルホリニルアニリノキナゾリン誘導体 |
CN1976944A (zh) | 2004-06-30 | 2007-06-06 | 默克公司 | 雌激素受体调节剂 |
EP1799218A1 (de) | 2004-09-30 | 2007-06-27 | Tibotec Pharmaceuticals Ltd. | Hcv-hemmende bicyclische pyrimidine |
GB0421908D0 (en) | 2004-10-01 | 2004-11-03 | Angeletti P Ist Richerche Bio | New uses |
AR054122A1 (es) | 2005-05-12 | 2007-06-06 | Tibotec Pharm Ltd | Pirido[2,3-d]pirimidas utiles como inhibidores de hcv, y metodos para la preparacion de las mismas |
AR056347A1 (es) | 2005-05-12 | 2007-10-03 | Tibotec Pharm Ltd | Uso de compuestos de pteridina para fabricar medicamentos y composiciones farmaceuticas |
ATE455117T1 (de) | 2005-09-23 | 2010-01-15 | Equispharm Co Ltd | 5,6-dimethylthienoä2,3-diüpyrimidinderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung für die bekämpfung von viren |
DE602006015861D1 (de) | 2005-12-21 | 2010-09-09 | Abbott Lab | Antivirale verbindungen |
ES2395386T3 (es) * | 2005-12-21 | 2013-02-12 | Abbott Laboratories | Compuestos antivirales |
-
2006
- 2006-12-20 DE DE602006015861T patent/DE602006015861D1/de active Active
- 2006-12-20 CA CA002633760A patent/CA2633760A1/en not_active Abandoned
- 2006-12-20 WO PCT/US2006/049080 patent/WO2007076035A2/en active Application Filing
- 2006-12-20 JP JP2008547625A patent/JP2009521480A/ja active Pending
- 2006-12-20 AT AT06848056T patent/ATE475660T1/de not_active IP Right Cessation
- 2006-12-20 US US11/613,836 patent/US7763731B2/en active Active
- 2006-12-20 CN CN2012101601285A patent/CN102702194A/zh active Pending
- 2006-12-20 EP EP06848056A patent/EP1979349B1/de active Active
- 2006-12-20 RU RU2008129807/04A patent/RU2467007C2/ru not_active IP Right Cessation
-
2009
- 2009-02-11 HK HK09101289.9A patent/HK1122292A1/xx not_active IP Right Cessation
-
2010
- 2010-06-17 US US12/817,808 patent/US8338605B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP1979349A2 (de) | 2008-10-15 |
JP2009521480A (ja) | 2009-06-04 |
RU2008129807A (ru) | 2010-02-20 |
RU2467007C2 (ru) | 2012-11-20 |
DE602006015861D1 (de) | 2010-09-09 |
US20070232645A1 (en) | 2007-10-04 |
HK1122292A1 (en) | 2009-05-15 |
US20100256139A1 (en) | 2010-10-07 |
WO2007076035A2 (en) | 2007-07-05 |
WO2007076035A3 (en) | 2007-10-04 |
CN102702194A (zh) | 2012-10-03 |
US7763731B2 (en) | 2010-07-27 |
US8338605B2 (en) | 2012-12-25 |
EP1979349B1 (de) | 2010-07-28 |
CA2633760A1 (en) | 2007-07-05 |
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