ATE475660T1 - Antivirale verbindungen - Google Patents
Antivirale verbindungenInfo
- Publication number
- ATE475660T1 ATE475660T1 AT06848056T AT06848056T ATE475660T1 AT E475660 T1 ATE475660 T1 AT E475660T1 AT 06848056 T AT06848056 T AT 06848056T AT 06848056 T AT06848056 T AT 06848056T AT E475660 T1 ATE475660 T1 AT E475660T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- antiviral compounds
- hcv
- viral
- syntheses
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75247305P | 2005-12-21 | 2005-12-21 | |
| US11/613,836 US7763731B2 (en) | 2005-12-21 | 2006-12-20 | Anti-viral compounds |
| PCT/US2006/049080 WO2007076035A2 (en) | 2005-12-21 | 2006-12-20 | Anti-viral compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE475660T1 true ATE475660T1 (de) | 2010-08-15 |
Family
ID=38069383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06848056T ATE475660T1 (de) | 2005-12-21 | 2006-12-20 | Antivirale verbindungen |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7763731B2 (de) |
| EP (1) | EP1979349B1 (de) |
| JP (1) | JP2009521480A (de) |
| CN (1) | CN102702194A (de) |
| AT (1) | ATE475660T1 (de) |
| CA (1) | CA2633760A1 (de) |
| DE (1) | DE602006015861D1 (de) |
| RU (1) | RU2467007C2 (de) |
| WO (1) | WO2007076035A2 (de) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602006015861D1 (de) | 2005-12-21 | 2010-09-09 | Abbott Lab | Antivirale verbindungen |
| NZ569817A (en) | 2005-12-21 | 2011-10-28 | Abbott Lab | Anti-viral compounds |
| WO2007081517A2 (en) | 2005-12-21 | 2007-07-19 | Abbott Laboratories | Anti-viral compounds |
| WO2008133753A2 (en) | 2006-12-20 | 2008-11-06 | Abbott Laboratories | Anti-viral compounds |
| US20110166123A1 (en) * | 2008-01-07 | 2011-07-07 | Aardea Biosciences, Inc. | Novel compositions and methods of use |
| EP2303841A1 (de) | 2008-07-14 | 2011-04-06 | Gilead Sciences, Inc. | Oxindolylhemmerverbindungen |
| CN102245604A (zh) * | 2008-12-23 | 2011-11-16 | 雅培制药有限公司 | 抗病毒化合物 |
| EP2367824B1 (de) * | 2008-12-23 | 2016-03-23 | AbbVie Inc. | Antivirale Pyrimidinderivate |
| WO2010098866A1 (en) | 2009-02-27 | 2010-09-02 | Supergen, Inc. | Cyclopentathiophene/cyclohexathiophene dna methyltransferase inhibitors |
| CA2758484A1 (en) * | 2009-04-15 | 2010-10-21 | David A. Degoey | Anti-viral compounds |
| WO2010144378A2 (en) | 2009-06-08 | 2010-12-16 | Gilead Colorado, Inc. | Cycloalkylcarbamate benzamide aniline hdac inhibitor compounds |
| JP5586692B2 (ja) | 2009-06-08 | 2014-09-10 | ギリアード サイエンシーズ, インコーポレイテッド | アルカノイルアミノベンズアミドアニリンhdacインヒビター化合物 |
| TWI402070B (zh) * | 2009-06-11 | 2013-07-21 | Abbott Lab | 抗病毒化合物 |
| US8937150B2 (en) | 2009-06-11 | 2015-01-20 | Abbvie Inc. | Anti-viral compounds |
| US9394279B2 (en) | 2009-06-11 | 2016-07-19 | Abbvie Inc. | Anti-viral compounds |
| US8716454B2 (en) | 2009-06-11 | 2014-05-06 | Abbvie Inc. | Solid compositions |
| US20110137633A1 (en) * | 2009-12-03 | 2011-06-09 | Abbott Laboratories | Anti-viral compounds and methods of identifying the same |
| NZ605440A (en) | 2010-06-10 | 2014-05-30 | Abbvie Bahamas Ltd | Solid compositions comprising an hcv inhibitor |
| PT3042910T (pt) | 2010-11-30 | 2019-04-16 | Gilead Pharmasset Llc | 2'-espiro-nucleósidos para utilização na terapia da hepatite c |
| US10201584B1 (en) | 2011-05-17 | 2019-02-12 | Abbvie Inc. | Compositions and methods for treating HCV |
| WO2013040492A2 (en) | 2011-09-16 | 2013-03-21 | Gilead Sciences, Inc. | Methods for treating hcv |
| US8889159B2 (en) | 2011-11-29 | 2014-11-18 | Gilead Pharmasset Llc | Compositions and methods for treating hepatitis C virus |
| US9034832B2 (en) | 2011-12-29 | 2015-05-19 | Abbvie Inc. | Solid compositions |
| BR112014031263B1 (pt) * | 2012-06-15 | 2022-03-29 | Curegenix Inc | Composto, composição farmacêutica, método de inibição da secreção wnt, método de inibição da sinalização wnt e uso de um composto |
| WO2014069063A1 (ja) | 2012-10-29 | 2014-05-08 | 京セラ株式会社 | 弾性表面波センサ |
| CA2890009C (en) | 2012-11-08 | 2017-11-28 | Pfizer Inc. | Heteroaromatic compounds and their use as dopamine d1 ligands |
| EP2950786B1 (de) | 2013-01-31 | 2019-11-27 | Gilead Pharmasset LLC | Kombinationsformulierung zweier antiviraler verbindungen |
| US11484534B2 (en) | 2013-03-14 | 2022-11-01 | Abbvie Inc. | Methods for treating HCV |
| EP3089757A1 (de) | 2014-01-03 | 2016-11-09 | AbbVie Inc. | Feste antivirale darreichungsformen |
| EP3134405B1 (de) | 2014-04-25 | 2019-08-28 | Pfizer Inc | Heteroaromatische verbindungen und deren verwendung als dopamin-d1-liganden |
| CN104086543A (zh) * | 2014-06-19 | 2014-10-08 | 湖南华腾制药有限公司 | 一种制备4-氯-1,8-二氮萘的方法 |
| EP3162796B1 (de) | 2014-06-27 | 2021-06-09 | Agro-Kanesho Co., Ltd. | Verfahren zur herstellung von 2-amino-6-methylnikotinsäure |
| US10131683B2 (en) | 2014-07-17 | 2018-11-20 | Molecular Templates, Inc. | TH-302 solid forms and methods related thereto |
| ES2828026T3 (es) | 2015-03-10 | 2021-05-25 | Obi Pharma Inc | Agentes alquilantes del ADN |
| MY198613A (en) | 2015-04-02 | 2023-09-11 | Ascenta Pharmaceuticals Ltd | Nitrobenzyl derivatives of anti-cancer agents |
| US20180169064A1 (en) | 2015-06-24 | 2018-06-21 | Threshold Pharmaceuticals, Inc. | Aziridine containing dna alkylating agents |
| IL283355B (en) * | 2015-07-21 | 2022-08-01 | Immunogen Inc | Methods for the preparation of cytotoxic benzodiazepine compounds |
| KR20180086187A (ko) | 2015-10-05 | 2018-07-30 | 더 트러스티이스 오브 콜롬비아 유니버시티 인 더 시티 오브 뉴욕 | 자가포식 유동의 활성체 및 포스포리파제 d 및 타우를 포함하는 단백질 응집물의 클리어런스 및 단백질질환의 치료 |
| CN105461582A (zh) * | 2015-11-18 | 2016-04-06 | 浙江汇能生物股份有限公司 | 一种碘醚柳胺的制备方法 |
| US10239875B2 (en) | 2017-06-16 | 2019-03-26 | King Saud University | Naphthyridinyl hydrazine derivatives as potent peripheral analgesic agents |
| EP3594205A1 (de) | 2018-07-09 | 2020-01-15 | Abivax | Phenyl-n-aryl-derivate zur behandlung einer rna-virusinfektion |
| EP3594206A1 (de) | 2018-07-09 | 2020-01-15 | Abivax | Phenyl-n-chinolin-derivate zur behandlung einer rna-virusinfektion |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5034393A (en) | 1989-07-27 | 1991-07-23 | Dowelanco | Fungicidal use of pyridopyrimidine, pteridine, pyrimidopyrimidine, pyrimidopyridazine, and pyrimido-1,2,4-triazine derivatives |
| GB9127252D0 (en) * | 1991-12-23 | 1992-02-19 | Boots Co Plc | Therapeutic agents |
| DE4308014A1 (de) * | 1993-03-13 | 1994-09-15 | Hoechst Schering Agrevo Gmbh | Kondensierte Stickstoffheterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel und Fungizide |
| GB9312891D0 (en) * | 1993-06-22 | 1993-08-04 | Boots Co Plc | Therapeutic agents |
| IL112249A (en) | 1994-01-25 | 2001-11-25 | Warner Lambert Co | Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds |
| US5679683A (en) * | 1994-01-25 | 1997-10-21 | Warner-Lambert Company | Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family |
| GB9510757D0 (en) | 1994-09-19 | 1995-07-19 | Wellcome Found | Therapeuticaly active compounds |
| WO1996040142A1 (en) | 1995-06-07 | 1996-12-19 | Pfizer Inc. | Heterocyclic ring-fused pyrimidine derivatives |
| US6037157A (en) * | 1995-06-29 | 2000-03-14 | Abbott Laboratories | Method for improving pharmacokinetics |
| US6130217A (en) * | 1995-09-20 | 2000-10-10 | Pfizer Inc | Compounds enhancing antitumor activity of other cytotoxic agents |
| AR004010A1 (es) | 1995-10-11 | 1998-09-30 | Glaxo Group Ltd | Compuestos heterociclicos |
| EA199900021A1 (ru) | 1996-07-13 | 1999-08-26 | Глаксо, Груп Лимитед | Бициклические гетероароматические соединения в качестве ингибиторов протеинтирозинкиназы |
| HRP970371A2 (en) | 1996-07-13 | 1998-08-31 | Kathryn Jane Smith | Heterocyclic compounds |
| FR2751330B1 (fr) | 1996-07-16 | 1998-10-30 | Pernod Ricard | Procede de production de derivees de diol-1,3 naturels et de derives de 1,3-dioxane naturels correspondants |
| ATE232863T1 (de) | 1996-08-06 | 2003-03-15 | Pfizer | Substituierte pyrido- oder pyrimidogruppen enthaltende 6,6- oder 6,7-bicyclische derivate |
| TW477787B (en) | 1996-08-27 | 2002-03-01 | Pfizer | Pyrido six-membered nitrogen-containing cyclic ring derivatives having corticotropin releasing factor antagonist activity and pharmaceutical composition containing same |
| ATE300521T1 (de) * | 1996-09-25 | 2005-08-15 | Astrazeneca Ab | Chinolin-derivate die den effekt von wachstumsfaktoren wie vegf vezögern |
| DE19647413A1 (de) | 1996-11-15 | 1998-05-20 | Hoechst Schering Agrevo Gmbh | Substituierte Stickstoff-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel |
| DE19647317A1 (de) * | 1996-11-15 | 1998-05-20 | Hoechst Schering Agrevo Gmbh | Substituierte Stickstoff-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel |
| IL129825A0 (en) * | 1996-11-27 | 2000-02-29 | Pfizer | Fused bicyclic pyrimidine derivatives |
| MXPA00008348A (es) * | 1998-02-25 | 2005-07-15 | Univ Emory | 2-fluronucleosidos. |
| AU7583098A (en) | 1998-05-20 | 1999-12-06 | Eli Lilly And Company | Anti-viral compounds |
| US6323180B1 (en) * | 1998-08-10 | 2001-11-27 | Boehringer Ingelheim (Canada) Ltd | Hepatitis C inhibitor tri-peptides |
| US6184226B1 (en) | 1998-08-28 | 2001-02-06 | Scios Inc. | Quinazoline derivatives as inhibitors of P-38 α |
| UA71945C2 (en) * | 1999-01-27 | 2005-01-17 | Pfizer Prod Inc | Substituted bicyclic derivatives being used as anticancer agents |
| GB9906566D0 (en) | 1999-03-23 | 1999-05-19 | Zeneca Ltd | Chemical compounds |
| AU1071301A (en) | 1999-11-01 | 2001-05-14 | Eli Lilly And Company | Pharmaceutical compounds |
| EP1225899A2 (de) | 1999-11-04 | 2002-07-31 | Virochem Pharma Inc. | Methode zur behandlung und vorbeugung von flaviviridae viralinfekten mit nukleosidanalogen |
| ID30204A (id) | 1999-12-27 | 2001-11-15 | Japan Tobacco Inc | Senyawa-senyawa cincin terfusi dan penggunaannya sebagai obat |
| ITMI992711A1 (it) * | 1999-12-27 | 2001-06-27 | Novartis Ag | Composti organici |
| WO2001057040A1 (en) | 2000-02-03 | 2001-08-09 | Abbott Laboratories | 6,7-disubstituted-4-aminopyrido[2,3-d]pyrimidine compounds |
| HUP0301112A3 (en) | 2000-02-18 | 2005-04-28 | Shire Biochem Inc Laval | Method for the treatment or prevention of flavivirus infections using nucleoside analogues |
| MY164523A (en) | 2000-05-23 | 2017-12-29 | Univ Degli Studi Cagliari | Methods and compositions for treating hepatitis c virus |
| US6448281B1 (en) | 2000-07-06 | 2002-09-10 | Boehringer Ingelheim (Canada) Ltd. | Viral polymerase inhibitors |
| US7622503B2 (en) * | 2000-08-24 | 2009-11-24 | University Of Tennessee Research Foundation | Selective androgen receptor modulators and methods of use thereof |
| KR20030036922A (ko) * | 2000-10-12 | 2003-05-09 | 머크 앤드 캄파니 인코포레이티드 | Hiv 인테그라제 억제제로서 유용한 아자- 및폴리아자-나프탈레닐 카복스아미드 |
| US20040110785A1 (en) * | 2001-02-02 | 2004-06-10 | Tao Wang | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives |
| AU2002259130A1 (en) * | 2001-05-03 | 2002-11-18 | Eli Lilly And Company | Agents for treatment of hcv and methods of use |
| US20030158195A1 (en) * | 2001-12-21 | 2003-08-21 | Cywin Charles L. | 1,6 naphthyridines useful as inhibitors of SYK kinase |
| US7037913B2 (en) * | 2002-05-01 | 2006-05-02 | Bristol-Myers Squibb Company | Bicyclo 4.4.0 antiviral derivatives |
| WO2004014852A2 (en) | 2002-08-12 | 2004-02-19 | Bristol-Myers Squibb Company | Iminothiazolidinones as inhibitors of hcv replication |
| US7358249B2 (en) | 2002-08-13 | 2008-04-15 | Shionogi & Co., Ltd. | Heterocyclic compounds having inhibitory activity against HIV integrase |
| US20050075331A1 (en) * | 2003-10-06 | 2005-04-07 | Pratt John K. | Anti-infective agents |
| WO2004047818A2 (en) | 2002-11-22 | 2004-06-10 | Scios, Inc. | USE OF TFG-β INHIBITORSTO COUNTERACT PATHOLOGIC CHANGES IN THE LEVEL OR FUNCTION OF STEROID/THYROID RECEPTORS |
| CA2509233A1 (en) | 2002-12-13 | 2004-07-01 | Neurogen Corporation | 2-substituted quinazolin-4-ylamine analogues as capsaicin receptor modulators |
| WO2004065392A1 (en) | 2003-01-24 | 2004-08-05 | Smithkline Beecham Corporation | Condensed pyridines and pyrimidines and their use as alk-5 receptor ligands |
| CA2520465A1 (en) | 2003-03-28 | 2004-10-14 | Scios Inc. | Bi-cyclic pyrimidine inhibitors of tgf.beta. |
| EP1636195A1 (de) * | 2003-05-27 | 2006-03-22 | Pfizer Products Inc. | Chinazoline und pyrido[3,4-d]pyrimidine als rezeptor tyrosin kinase inhibitoren |
| TW200510373A (en) * | 2003-07-14 | 2005-03-16 | Neurogen Corp | Substituted quinolin-4-ylamine analogues |
| US7378414B2 (en) * | 2003-08-25 | 2008-05-27 | Abbott Laboratories | Anti-infective agents |
| GB0326168D0 (en) * | 2003-11-10 | 2003-12-17 | Arrow Therapeutics Ltd | Chemical compounds |
| CA2564175A1 (en) | 2004-04-28 | 2005-11-10 | Arrow Therapeutics Limited | Chemical compounds |
| EP1773862A1 (de) | 2004-06-30 | 2007-04-18 | Merck & Co., Inc. | Östrogenrezeptormodulatoren |
| BRPI0516751A (pt) | 2004-09-30 | 2008-09-16 | Tibotec Pharm Ltd | pirimidinas bicìclicas que inibem hcv |
| GB0421908D0 (en) | 2004-10-01 | 2004-11-03 | Angeletti P Ist Richerche Bio | New uses |
| AR056347A1 (es) | 2005-05-12 | 2007-10-03 | Tibotec Pharm Ltd | Uso de compuestos de pteridina para fabricar medicamentos y composiciones farmaceuticas |
| TW200716631A (en) | 2005-05-12 | 2007-05-01 | Tibotec Pharm Ltd | Pyrido[2,3-d]pyrimidines useful as HCV inhibitors, and methods for the preparation thereof |
| US7816351B2 (en) | 2005-09-23 | 2010-10-19 | Equispharm Co., Ltd | 5,6-dimethylthieno[2,3-di] pyrimidine derivatives, the preparation method thereof and the pharmaceutical composition comprising the same for anti-virus |
| WO2007081517A2 (en) * | 2005-12-21 | 2007-07-19 | Abbott Laboratories | Anti-viral compounds |
| DE602006015861D1 (de) | 2005-12-21 | 2010-09-09 | Abbott Lab | Antivirale verbindungen |
-
2006
- 2006-12-20 DE DE602006015861T patent/DE602006015861D1/de active Active
- 2006-12-20 WO PCT/US2006/049080 patent/WO2007076035A2/en not_active Ceased
- 2006-12-20 EP EP06848056A patent/EP1979349B1/de active Active
- 2006-12-20 AT AT06848056T patent/ATE475660T1/de not_active IP Right Cessation
- 2006-12-20 US US11/613,836 patent/US7763731B2/en active Active
- 2006-12-20 CA CA002633760A patent/CA2633760A1/en not_active Abandoned
- 2006-12-20 CN CN2012101601285A patent/CN102702194A/zh active Pending
- 2006-12-20 JP JP2008547625A patent/JP2009521480A/ja active Pending
- 2006-12-20 RU RU2008129807/04A patent/RU2467007C2/ru not_active IP Right Cessation
-
2010
- 2010-06-17 US US12/817,808 patent/US8338605B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007076035A3 (en) | 2007-10-04 |
| US20070232645A1 (en) | 2007-10-04 |
| US8338605B2 (en) | 2012-12-25 |
| US20100256139A1 (en) | 2010-10-07 |
| RU2467007C2 (ru) | 2012-11-20 |
| HK1122292A1 (en) | 2009-05-15 |
| RU2008129807A (ru) | 2010-02-20 |
| US7763731B2 (en) | 2010-07-27 |
| EP1979349A2 (de) | 2008-10-15 |
| CA2633760A1 (en) | 2007-07-05 |
| CN102702194A (zh) | 2012-10-03 |
| JP2009521480A (ja) | 2009-06-04 |
| EP1979349B1 (de) | 2010-07-28 |
| WO2007076035A2 (en) | 2007-07-05 |
| DE602006015861D1 (de) | 2010-09-09 |
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