EA200001208A1 - Противовирусные соединения - Google Patents

Противовирусные соединения

Info

Publication number
EA200001208A1
EA200001208A1 EA200001208A EA200001208A EA200001208A1 EA 200001208 A1 EA200001208 A1 EA 200001208A1 EA 200001208 A EA200001208 A EA 200001208A EA 200001208 A EA200001208 A EA 200001208A EA 200001208 A1 EA200001208 A1 EA 200001208A1
Authority
EA
Eurasian Patent Office
Prior art keywords
alkyl
hydrogen
halogen
virus
formula
Prior art date
Application number
EA200001208A
Other languages
English (en)
Russian (ru)
Inventor
Хесус Эскера-Каррера
Джозеф Майкл Грубер
Чафик Амдоучи Амдоучи
Ричард Элмер Холмс
Вейн Альфред Шпицер
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of EA200001208A1 publication Critical patent/EA200001208A1/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EA200001208A 1998-05-20 1998-05-20 Противовирусные соединения EA200001208A1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1998/010299 WO1999059587A1 (en) 1998-05-20 1998-05-20 Anti-viral compounds

Publications (1)

Publication Number Publication Date
EA200001208A1 true EA200001208A1 (ru) 2001-06-25

Family

ID=22267098

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200001208A EA200001208A1 (ru) 1998-05-20 1998-05-20 Противовирусные соединения

Country Status (15)

Country Link
EP (1) EP1077701A4 (cs)
JP (1) JP2002515433A (cs)
KR (1) KR20010025055A (cs)
CN (1) CN1292697A (cs)
AU (1) AU7583098A (cs)
BR (1) BR9815899A (cs)
CA (1) CA2332403A1 (cs)
CZ (1) CZ289425B6 (cs)
EA (1) EA200001208A1 (cs)
HU (1) HUP0102117A2 (cs)
IL (1) IL139166A0 (cs)
NO (1) NO20005795L (cs)
SK (1) SK17482000A3 (cs)
TR (1) TR200003414T2 (cs)
WO (1) WO1999059587A1 (cs)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR213700A0 (en) 2000-12-18 2001-01-25 Biota Scientific Management Pty Ltd Antiviral agents
AR048650A1 (es) * 2004-05-04 2006-05-10 Tibotec Pharm Ltd Derivados de (1,10b-dihidro-2-(aminocarbonil-fenil)-5h-pirazolo[1,5 c][1,3]benzoxazin-5-il)fenil metanona como inhibidores de la replicacion viral del vih
DE602005020313D1 (de) 2004-08-12 2010-05-12 Amgen Inc Bisaryl-sulfonamide
US7666880B2 (en) 2005-03-21 2010-02-23 S*Bio Pte Ltd. Imidazo[1,2-A]pyridine derivatives: preparation and pharmaceutical applications
MY147647A (en) * 2005-03-21 2012-12-31 S Bio Pte Ltd Imidazo [1,2-a] pyridine derivatives : preparation and pharmaceutical applications
CA2633760A1 (en) 2005-12-21 2007-07-05 Abbott Laboratories Anti-viral compounds
ES2395386T3 (es) 2005-12-21 2013-02-12 Abbott Laboratories Compuestos antivirales
ES2378473T3 (es) 2005-12-21 2012-04-12 Abbott Laboratories Compuestos antivirales
WO2008133753A2 (en) 2006-12-20 2008-11-06 Abbott Laboratories Anti-viral compounds
NZ590286A (en) * 2008-05-27 2011-08-26 Biota Scient Management Phosphate and sulphate salts of 6-{ 2-[1-(6-methyl-3-pyrazinyl)-4-piperidinyl]ethoxy} -3-ethoxy-1,2-benzisoxazole
WO2010075380A1 (en) 2008-12-23 2010-07-01 Abbott Laboratories Anti-viral compounds
CA2740193A1 (en) 2008-12-23 2010-07-01 Abbott Laboratories Anti-viral compounds
EP2419404B1 (en) 2009-04-15 2015-11-04 AbbVie Inc. Anti-viral compounds
WO2014060381A1 (de) 2012-10-18 2014-04-24 Bayer Cropscience Ag Heterocyclische verbindungen als schädlingsbekämpfungsmittel
CN104884449A (zh) 2012-10-31 2015-09-02 拜尔农作物科学股份公司 作为害虫防治剂的新的杂环化合物
CN104370732B (zh) * 2014-01-26 2015-08-19 山东信立泰药业有限公司 一种氯吡格雷及其中间体的制备方法
CN109535405B (zh) * 2017-09-21 2021-07-30 宁波聚嘉新材料科技有限公司 一种基于2-(4-羧基苯基)-5-羟基吡啶并咪唑的聚芳酯的制备方法
CN109810085B (zh) * 2019-04-19 2019-07-19 上海皓元生物医药科技有限公司 Acc抑制剂及其中间体的制备方法
CN110746450A (zh) * 2019-09-17 2020-02-04 济南康和医药科技有限公司 一种贝前列素钠关键中间体的合成方法
CN117902992A (zh) * 2024-01-04 2024-04-19 浙江永太科技股份有限公司 一种2,4-二氟苯基甘氨酸的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4096264A (en) * 1975-12-09 1978-06-20 Merck & Co., Inc. Certain substituted imidazo [1,2-a] pyridines
US4250174A (en) * 1979-05-02 1981-02-10 Merck & Co., Inc. 3-Substituted imidazo [1,2-A] pyridines
US5693661A (en) * 1995-06-07 1997-12-02 Eli Lilly And Company Anti-viral compounds
EA001316B1 (ru) * 1996-06-05 2001-02-26 Эли Лилли Энд Компании Соединения, обладающие антивирусной активностью
US5891874A (en) * 1996-06-05 1999-04-06 Eli Lilly And Company Anti-viral compound
US5821242A (en) * 1996-06-06 1998-10-13 Eli Lilly And Company Anti-viral compounds

Also Published As

Publication number Publication date
EP1077701A1 (en) 2001-02-28
HUP0102117A2 (hu) 2001-12-28
NO20005795D0 (no) 2000-11-16
CA2332403A1 (en) 1999-11-25
CZ20004278A3 (en) 2001-05-16
CN1292697A (zh) 2001-04-25
KR20010025055A (ko) 2001-03-26
SK17482000A3 (sk) 2005-03-04
NO20005795L (no) 2001-01-18
TR200003414T2 (tr) 2001-03-21
WO1999059587A1 (en) 1999-11-25
AU7583098A (en) 1999-12-06
CZ289425B6 (cs) 2002-01-16
JP2002515433A (ja) 2002-05-28
EP1077701A4 (en) 2002-03-20
BR9815899A (pt) 2001-02-20
IL139166A0 (en) 2001-11-25

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