HUP0000943A2 - Expandálható gasztro-retentív terápiás rendszer szabályozott hatóanyag felszabadítással a gyomor-béltraktusban - Google Patents
Expandálható gasztro-retentív terápiás rendszer szabályozott hatóanyag felszabadítással a gyomor-béltraktusbanInfo
- Publication number
- HUP0000943A2 HUP0000943A2 HU0000943A HUP0000943A HUP0000943A2 HU P0000943 A2 HUP0000943 A2 HU P0000943A2 HU 0000943 A HU0000943 A HU 0000943A HU P0000943 A HUP0000943 A HU P0000943A HU P0000943 A2 HUP0000943 A2 HU P0000943A2
- Authority
- HU
- Hungary
- Prior art keywords
- gastro
- active substance
- expandable
- retentive
- intestinal tract
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title abstract 6
- 210000001035 gastrointestinal tract Anatomy 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title 1
- 210000004051 gastric juice Anatomy 0.000 abstract 3
- 230000003111 delayed effect Effects 0.000 abstract 2
- 239000002775 capsule Substances 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/009—Sachets, pouches characterised by the material or function of the envelope
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Anesthesiology (AREA)
- Wood Science & Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A találmány egy gyógyszerformát ír le hatóanyagok szabályozottfelszabadításához a gyomor-bél-traktusban késleltetett pylorus-pasz-százzsal egy a gyomornedvvel érintkező expandálható komponenssel, melyvalamely a gyomornedv és hatóanyagok számára permeábilispolimerburokkal van körülvéve. A gyógyszerforma legalább egyhatóanyagot tartalmaz, mely valamely multipartikuláris készítménybenvan, mely a hatóanyagot retardálva a gyomornedvbe lead. Szemben aszokásos gyógyszerformákkal, késleltetett pylorus-passzázzsal ahatóanyag-felszabadítás egy találmány szerinti gyógyszerformábóljobban szabályozható; hasonlóképpen a gyógyszerforma könnyen sodorhatóvagy redőzhető és problémamentesen vihető be a kapszulákba. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19700915 | 1997-01-14 | ||
PCT/EP1998/000099 WO1998031341A1 (de) | 1997-01-14 | 1998-01-09 | Expandierbares gastroretentives therapie-system mit kontrollierter wirkstofffreisetzung im gastrointestinaltrakt |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0000943A2 true HUP0000943A2 (hu) | 2000-10-28 |
HUP0000943A3 HUP0000943A3 (en) | 2000-11-28 |
HU224224B1 HU224224B1 (hu) | 2005-06-28 |
Family
ID=7817288
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0000943A HU224224B1 (hu) | 1997-01-14 | 1998-01-09 | Expandálható gasztroretentív terápiás rendszer szabályozott hatóanyagfelszabadulással a gyomor-bél traktusban |
Country Status (20)
Country | Link |
---|---|
US (1) | US6290989B1 (hu) |
EP (1) | EP0961611B1 (hu) |
JP (1) | JP3825811B2 (hu) |
KR (1) | KR100503266B1 (hu) |
AT (1) | ATE214916T1 (hu) |
AU (1) | AU727753B2 (hu) |
CA (1) | CA2277277C (hu) |
CZ (1) | CZ297098B6 (hu) |
DE (2) | DE19800523C2 (hu) |
DK (1) | DK0961611T3 (hu) |
ES (1) | ES2175676T3 (hu) |
HU (1) | HU224224B1 (hu) |
ID (1) | ID22698A (hu) |
IL (1) | IL130872A (hu) |
NO (1) | NO993383L (hu) |
NZ (1) | NZ336691A (hu) |
PL (1) | PL193282B1 (hu) |
PT (1) | PT961611E (hu) |
SK (1) | SK93999A3 (hu) |
WO (1) | WO1998031341A1 (hu) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19822278A1 (de) * | 1998-05-18 | 1999-12-02 | Lohmann Therapie Syst Lts | Vorrichtung zur kontrollierten Freisetzung von Wirkstoff im Gastrointestinaltrakt mit verzögerter Pyloruspassage |
DE19837073A1 (de) * | 1998-08-17 | 2000-03-23 | Lohmann Therapie Syst Lts | Folienförmige Wirkstoffträger |
DE19849848A1 (de) * | 1998-10-29 | 2000-05-04 | Lohmann Therapie Syst Lts | Oral applizierbare, mit Flüssigkeit spontan zerfallende therapeutische Darreichungsform und Verfahren zu ihrer Herstellung |
DE19850309A1 (de) * | 1998-10-30 | 2000-05-04 | Lohmann Therapie Syst Lts | Expandierbares gastroretensives Therapiesystem mit verlängerter Magenverweildauer |
DE19920854A1 (de) * | 1999-05-06 | 2000-11-16 | Lohmann Therapie Syst Lts | Verfahren und Vorrichtung zum Herstellen eines gastroretentiven flachen Schlauchbeutels mit Längsnaht |
DE19920838A1 (de) * | 1999-05-06 | 2000-11-16 | Lohmann Therapie Syst Lts | Gastroretentives System mit Kapillaren |
DE19920833A1 (de) * | 1999-05-06 | 2000-11-16 | Lohmann Therapie Syst Lts | Gastroretentives System mit quellbaren Polymeren |
DE19920837A1 (de) * | 1999-05-06 | 2000-11-16 | Lohmann Therapie Syst Lts | Gastroretentives System für verlängerte Verweilzeit im Magen bzw. im Gastrointestinaltrakt |
DE19920855A1 (de) * | 1999-05-06 | 2000-11-16 | Lohmann Therapie Syst Lts | Magenvolumenreduzierende Darreichungsform |
MXPA02007254A (es) | 2000-02-04 | 2002-12-09 | Depomed Inc | Forma de dosis de cubierta-y-nucleo que se aproxima a liberacion de droga de orden cero. |
GB0102725D0 (en) * | 2001-02-02 | 2001-03-21 | Stowic Resources Ltd | Medical delivery system |
EP1245227A1 (en) | 2001-03-31 | 2002-10-02 | Jagotec Ag | A pharmaceutical tablet system that floats in the stomach for programmed release of active substance and process of producing buoyant material contained in same |
AU2002356719A1 (en) * | 2001-12-17 | 2003-06-30 | Gunther Beisel | Agent for oral administration and method for producing the same |
US6869333B2 (en) * | 2002-09-11 | 2005-03-22 | National Optronics, Inc. | Lens blank alignment and blocking device and method |
WO2004032906A1 (en) * | 2002-10-11 | 2004-04-22 | Depomed Development, Ltd. | Gastro-retentive levodopa delivery form |
TW200533391A (en) | 2004-03-25 | 2005-10-16 | Sun Pharmaceutical Ind Ltd | Gastric retention drug delivery system |
EP1786378A2 (en) * | 2004-07-30 | 2007-05-23 | Merrion Research II Limited | Improved process and machine for automated manufacture of gastro-retentive devices |
US8852083B2 (en) * | 2005-02-04 | 2014-10-07 | Uti Limited Partnership | Self-stabilized encapsulated imaging system |
WO2006088305A1 (en) * | 2005-02-15 | 2006-08-24 | Chong Kun Dang Pharmaceutical Corp. | Gastric-retentive controlled release mono-matrix tablet |
JP2009523175A (ja) * | 2006-01-10 | 2009-06-18 | パイペックス,インコーポレイテッド | 目標とされる安定な銅状態を達成及び維持して銅関連中枢神経系疾患を予防及び治療するための医薬組成物及び方法 |
MX2008012587A (es) * | 2006-03-29 | 2009-01-14 | Electronic Dietary Foods Inc | Implemento ingerible para control de peso. |
US9579227B2 (en) * | 2006-03-29 | 2017-02-28 | Eat Little Inc. | Ingestible implement for weight control |
US8795721B2 (en) * | 2006-12-18 | 2014-08-05 | Eatlittle Inc. | Device for delivery of a substance |
US20080286343A1 (en) * | 2007-05-16 | 2008-11-20 | Dzenana Cengic | Solid form |
EP2490677A2 (en) * | 2009-10-19 | 2012-08-29 | Intec Pharma Ltd. | Novel gastroretentive dosage forms of poorly soluble drugs |
US20140343452A1 (en) * | 2011-12-21 | 2014-11-20 | Eatlittle Inc. | Pseudobezoar-Based Intraluminal Gastrointestinal Cleansing and Biospy |
CA3201057A1 (en) | 2020-12-08 | 2022-06-16 | Mark Christopher LAY | Improvements to devices and methods for delivery of substances to animals |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4207890A (en) | 1977-01-04 | 1980-06-17 | Mcneilab, Inc. | Drug-dispensing device and method |
DE3400106A1 (de) | 1984-01-04 | 1985-07-11 | Klaus-Dieter Dr. 3550 Marburg Bremecker | Pharmazeutische zubereitungen mit gesteuerter arzneistoff-freisetzung |
JPS63501794A (ja) * | 1985-10-09 | 1988-07-21 | デジテイン アルツナイミツテル ゲ−エムベ−ハ− | 医薬有効物質,試薬,その他の作用物質の提供ないし投与形態の製造法 |
IL87710A (en) * | 1987-09-18 | 1992-06-21 | Ciba Geigy Ag | Covered floating retard form for controlled release in gastric juice |
DE3812799A1 (de) * | 1988-04-16 | 1989-10-26 | Sanol Arznei Schwarz Gmbh | Oral zu verabreichende pharmazeutische zubereitung mit kontrollierter wirkstofffreisetzung und verfahren zu deren herstellung |
EP0408496A3 (en) * | 1989-07-12 | 1992-07-01 | Ciba-Geigy Ag | Solid dosage form for pharmaceutical substances |
CA2085871C (en) * | 1991-12-27 | 2002-05-07 | Gerald S. Rork | A controlled release drug dispersion delivery device |
GB9202519D0 (en) * | 1992-02-06 | 1992-03-25 | Glaxo Group Ltd | Medicaments |
US5260069A (en) | 1992-11-27 | 1993-11-09 | Anda Sr Pharmaceuticals Inc. | Pulsatile particles drug delivery system |
DE4406424A1 (de) | 1994-02-28 | 1995-08-31 | Bayer Ag | Expandierbare Arzneiformen |
-
1998
- 1998-01-09 KR KR10-1999-7006405A patent/KR100503266B1/ko not_active IP Right Cessation
- 1998-01-09 ES ES98906865T patent/ES2175676T3/es not_active Expired - Lifetime
- 1998-01-09 EP EP98906865A patent/EP0961611B1/de not_active Expired - Lifetime
- 1998-01-09 PL PL334834A patent/PL193282B1/pl not_active IP Right Cessation
- 1998-01-09 JP JP53131998A patent/JP3825811B2/ja not_active Expired - Fee Related
- 1998-01-09 ID IDW990690A patent/ID22698A/id unknown
- 1998-01-09 AU AU62922/98A patent/AU727753B2/en not_active Ceased
- 1998-01-09 WO PCT/EP1998/000099 patent/WO1998031341A1/de active IP Right Grant
- 1998-01-09 US US09/341,492 patent/US6290989B1/en not_active Expired - Fee Related
- 1998-01-09 CA CA002277277A patent/CA2277277C/en not_active Expired - Fee Related
- 1998-01-09 HU HU0000943A patent/HU224224B1/hu not_active IP Right Cessation
- 1998-01-09 AT AT98906865T patent/ATE214916T1/de active
- 1998-01-09 DE DE19800523A patent/DE19800523C2/de not_active Expired - Fee Related
- 1998-01-09 SK SK939-99A patent/SK93999A3/sk unknown
- 1998-01-09 CZ CZ0249599A patent/CZ297098B6/cs not_active IP Right Cessation
- 1998-01-09 IL IL13087298A patent/IL130872A/en not_active IP Right Cessation
- 1998-01-09 DE DE59803511T patent/DE59803511D1/de not_active Expired - Lifetime
- 1998-01-09 NZ NZ336691A patent/NZ336691A/xx not_active IP Right Cessation
- 1998-01-09 PT PT98906865T patent/PT961611E/pt unknown
- 1998-01-09 DK DK98906865T patent/DK0961611T3/da active
-
1999
- 1999-07-08 NO NO993383A patent/NO993383L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CZ297098B6 (cs) | 2006-09-13 |
DE19800523C2 (de) | 1999-01-21 |
KR20000070179A (ko) | 2000-11-25 |
US6290989B1 (en) | 2001-09-18 |
ES2175676T3 (es) | 2002-11-16 |
NZ336691A (en) | 2000-05-26 |
CZ249599A3 (cs) | 2000-01-12 |
DK0961611T3 (da) | 2002-07-15 |
SK93999A3 (en) | 2000-01-18 |
AU6292298A (en) | 1998-08-07 |
WO1998031341A1 (de) | 1998-07-23 |
NO993383D0 (no) | 1999-07-08 |
PL193282B1 (pl) | 2007-01-31 |
IL130872A0 (en) | 2001-01-28 |
AU727753B2 (en) | 2000-12-21 |
JP2001508068A (ja) | 2001-06-19 |
IL130872A (en) | 2004-02-19 |
HUP0000943A3 (en) | 2000-11-28 |
JP3825811B2 (ja) | 2006-09-27 |
PL334834A1 (en) | 2000-03-27 |
DE19800523A1 (de) | 1998-07-30 |
NO993383L (no) | 1999-07-08 |
ID22698A (id) | 1999-12-09 |
KR100503266B1 (ko) | 2005-07-25 |
HU224224B1 (hu) | 2005-06-28 |
DE59803511D1 (de) | 2002-05-02 |
PT961611E (pt) | 2002-09-30 |
ATE214916T1 (de) | 2002-04-15 |
CA2277277A1 (en) | 1998-07-23 |
CA2277277C (en) | 2005-03-08 |
EP0961611A2 (de) | 1999-12-08 |
EP0961611B1 (de) | 2002-03-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HFG4 | Patent granted, date of granting |
Effective date: 20050509 |
|
MM4A | Lapse of definitive patent protection due to non-payment of fees |