HUP0000943A2 - Expandálható gasztro-retentív terápiás rendszer szabályozott hatóanyag felszabadítással a gyomor-béltraktusban - Google Patents

Expandálható gasztro-retentív terápiás rendszer szabályozott hatóanyag felszabadítással a gyomor-béltraktusban

Info

Publication number
HUP0000943A2
HUP0000943A2 HU0000943A HUP0000943A HUP0000943A2 HU P0000943 A2 HUP0000943 A2 HU P0000943A2 HU 0000943 A HU0000943 A HU 0000943A HU P0000943 A HUP0000943 A HU P0000943A HU P0000943 A2 HUP0000943 A2 HU P0000943A2
Authority
HU
Hungary
Prior art keywords
gastro
active substance
expandable
retentive
intestinal tract
Prior art date
Application number
HU0000943A
Other languages
English (en)
Inventor
Bodo Asmussen
Karsten Cremer
Hans-Rainer Hoffmann
Karin Ludwig
Michael Roreger
Original Assignee
Lts Lohmann Therapie-Systeme Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lts Lohmann Therapie-Systeme Gmbh filed Critical Lts Lohmann Therapie-Systeme Gmbh
Publication of HUP0000943A2 publication Critical patent/HUP0000943A2/hu
Publication of HUP0000943A3 publication Critical patent/HUP0000943A3/hu
Publication of HU224224B1 publication Critical patent/HU224224B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009—Sachets, pouches characterised by the material or function of the envelope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A találmány egy gyógyszerformát ír le hatóanyagok szabályozottfelszabadításához a gyomor-bél-traktusban késleltetett pylorus-pasz-százzsal egy a gyomornedvvel érintkező expandálható komponenssel, melyvalamely a gyomornedv és hatóanyagok számára permeábilispolimerburokkal van körülvéve. A gyógyszerforma legalább egyhatóanyagot tartalmaz, mely valamely multipartikuláris készítménybenvan, mely a hatóanyagot retardálva a gyomornedvbe lead. Szemben aszokásos gyógyszerformákkal, késleltetett pylorus-passzázzsal ahatóanyag-felszabadítás egy találmány szerinti gyógyszerformábóljobban szabályozható; hasonlóképpen a gyógyszerforma könnyen sodorhatóvagy redőzhető és problémamentesen vihető be a kapszulákba. Ó
HU0000943A 1997-01-14 1998-01-09 Expandálható gasztroretentív terápiás rendszer szabályozott hatóanyagfelszabadulással a gyomor-bél traktusban HU224224B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19700915 1997-01-14
PCT/EP1998/000099 WO1998031341A1 (de) 1997-01-14 1998-01-09 Expandierbares gastroretentives therapie-system mit kontrollierter wirkstofffreisetzung im gastrointestinaltrakt

Publications (3)

Publication Number Publication Date
HUP0000943A2 true HUP0000943A2 (hu) 2000-10-28
HUP0000943A3 HUP0000943A3 (en) 2000-11-28
HU224224B1 HU224224B1 (hu) 2005-06-28

Family

ID=7817288

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0000943A HU224224B1 (hu) 1997-01-14 1998-01-09 Expandálható gasztroretentív terápiás rendszer szabályozott hatóanyagfelszabadulással a gyomor-bél traktusban

Country Status (20)

Country Link
US (1) US6290989B1 (hu)
EP (1) EP0961611B1 (hu)
JP (1) JP3825811B2 (hu)
KR (1) KR100503266B1 (hu)
AT (1) ATE214916T1 (hu)
AU (1) AU727753B2 (hu)
CA (1) CA2277277C (hu)
CZ (1) CZ297098B6 (hu)
DE (2) DE59803511D1 (hu)
DK (1) DK0961611T3 (hu)
ES (1) ES2175676T3 (hu)
HU (1) HU224224B1 (hu)
ID (1) ID22698A (hu)
IL (1) IL130872A (hu)
NO (1) NO993383L (hu)
NZ (1) NZ336691A (hu)
PL (1) PL193282B1 (hu)
PT (1) PT961611E (hu)
SK (1) SK93999A3 (hu)
WO (1) WO1998031341A1 (hu)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19822278A1 (de) * 1998-05-18 1999-12-02 Lohmann Therapie Syst Lts Vorrichtung zur kontrollierten Freisetzung von Wirkstoff im Gastrointestinaltrakt mit verzögerter Pyloruspassage
DE19837073A1 (de) * 1998-08-17 2000-03-23 Lohmann Therapie Syst Lts Folienförmige Wirkstoffträger
DE19849848A1 (de) * 1998-10-29 2000-05-04 Lohmann Therapie Syst Lts Oral applizierbare, mit Flüssigkeit spontan zerfallende therapeutische Darreichungsform und Verfahren zu ihrer Herstellung
DE19850309A1 (de) * 1998-10-30 2000-05-04 Lohmann Therapie Syst Lts Expandierbares gastroretensives Therapiesystem mit verlängerter Magenverweildauer
DE19920854A1 (de) * 1999-05-06 2000-11-16 Lohmann Therapie Syst Lts Verfahren und Vorrichtung zum Herstellen eines gastroretentiven flachen Schlauchbeutels mit Längsnaht
DE19920833A1 (de) * 1999-05-06 2000-11-16 Lohmann Therapie Syst Lts Gastroretentives System mit quellbaren Polymeren
DE19920837A1 (de) * 1999-05-06 2000-11-16 Lohmann Therapie Syst Lts Gastroretentives System für verlängerte Verweilzeit im Magen bzw. im Gastrointestinaltrakt
DE19920855A1 (de) * 1999-05-06 2000-11-16 Lohmann Therapie Syst Lts Magenvolumenreduzierende Darreichungsform
DE19920838A1 (de) * 1999-05-06 2000-11-16 Lohmann Therapie Syst Lts Gastroretentives System mit Kapillaren
CA2396782A1 (en) * 2000-02-04 2001-08-09 Depomed, Inc. Shell-and-core dosage form approaching zero-order drug release
GB0102725D0 (en) * 2001-02-02 2001-03-21 Stowic Resources Ltd Medical delivery system
EP1245227A1 (en) 2001-03-31 2002-10-02 Jagotec Ag A pharmaceutical tablet system that floats in the stomach for programmed release of active substance and process of producing buoyant material contained in same
WO2003051329A1 (de) * 2001-12-17 2003-06-26 Beisel Guenther Mittel zur oralen einnahme und verfahren zu dessen herstellung
US6869333B2 (en) * 2002-09-11 2005-03-22 National Optronics, Inc. Lens blank alignment and blocking device and method
US20040180086A1 (en) * 2002-10-11 2004-09-16 Zebunnissa Ramtoola Gastro-retentive levodopa delivery form
TW200533391A (en) 2004-03-25 2005-10-16 Sun Pharmaceutical Ind Ltd Gastric retention drug delivery system
EP1786378A2 (en) * 2004-07-30 2007-05-23 Merrion Research II Limited Improved process and machine for automated manufacture of gastro-retentive devices
US8852083B2 (en) * 2005-02-04 2014-10-07 Uti Limited Partnership Self-stabilized encapsulated imaging system
WO2006088305A1 (en) * 2005-02-15 2006-08-24 Chong Kun Dang Pharmaceutical Corp. Gastric-retentive controlled release mono-matrix tablet
JP2009523175A (ja) * 2006-01-10 2009-06-18 パイペックス，インコーポレイテッド 目標とされる安定な銅状態を達成及び維持して銅関連中枢神経系疾患を予防及び治療するための医薬組成物及び方法
US9579227B2 (en) * 2006-03-29 2017-02-28 Eat Little Inc. Ingestible implement for weight control
MX2008012587A (es) * 2006-03-29 2009-01-14 Electronic Dietary Foods Inc Implemento ingerible para control de peso.
CA2672602C (en) * 2006-12-18 2014-05-20 Electronic Dietary Foods Inc. Device for delivery of a substance
US20080286343A1 (en) * 2007-05-16 2008-11-20 Dzenana Cengic Solid form
EP2490677A2 (en) * 2009-10-19 2012-08-29 Intec Pharma Ltd. Novel gastroretentive dosage forms of poorly soluble drugs
WO2013091093A1 (en) * 2011-12-21 2013-06-27 Eatlittle, Inc. Pseudobezoar-based intraluminal gastrointestinal cleansing and biopsy
EP4037666B1 (en) 2020-12-08 2024-05-01 Ruminant Biotech Corp Limited Improvements to devices and methods for delivery of substances to animals

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Publication number Priority date Publication date Assignee Title
US4207890A (en) * 1977-01-04 1980-06-17 Mcneilab, Inc. Drug-dispensing device and method
DE3400106A1 (de) * 1984-01-04 1985-07-11 Klaus-Dieter Dr. 3550 Marburg Bremecker Pharmazeutische zubereitungen mit gesteuerter arzneistoff-freisetzung
WO1987002241A1 (en) * 1985-10-09 1987-04-23 Desitin Arzneimittel Gmbh Process for producing an administration or dosage form of drugs, reagents or other active ingredients
IL87710A (en) * 1987-09-18 1992-06-21 Ciba Geigy Ag Covered floating retard form for controlled release in gastric juice
DE3812799A1 (de) 1988-04-16 1989-10-26 Sanol Arznei Schwarz Gmbh Oral zu verabreichende pharmazeutische zubereitung mit kontrollierter wirkstofffreisetzung und verfahren zu deren herstellung
EP0408496A3 (en) * 1989-07-12 1992-07-01 Ciba-Geigy Ag Solid dosage form for pharmaceutical substances
HU219594B (hu) * 1991-12-27 2001-05-28 Merck And Co. Inc. Szabályozott diszperziós hatóanyag-leadó eszköz és eljárás előállítására
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Also Published As

Publication number Publication date
JP3825811B2 (ja) 2006-09-27
NZ336691A (en) 2000-05-26
IL130872A (en) 2004-02-19
DE19800523A1 (de) 1998-07-30
PL193282B1 (pl) 2007-01-31
ID22698A (id) 1999-12-09
WO1998031341A1 (de) 1998-07-23
HU224224B1 (hu) 2005-06-28
KR100503266B1 (ko) 2005-07-25
AU727753B2 (en) 2000-12-21
PL334834A1 (en) 2000-03-27
NO993383D0 (no) 1999-07-08
DK0961611T3 (da) 2002-07-15
PT961611E (pt) 2002-09-30
US6290989B1 (en) 2001-09-18
DE59803511D1 (de) 2002-05-02
ATE214916T1 (de) 2002-04-15
CA2277277C (en) 2005-03-08
JP2001508068A (ja) 2001-06-19
ES2175676T3 (es) 2002-11-16
DE19800523C2 (de) 1999-01-21
NO993383L (no) 1999-07-08
EP0961611B1 (de) 2002-03-27
KR20000070179A (ko) 2000-11-25
IL130872A0 (en) 2001-01-28
CA2277277A1 (en) 1998-07-23
AU6292298A (en) 1998-08-07
CZ297098B6 (cs) 2006-09-13
SK93999A3 (en) 2000-01-18
HUP0000943A3 (en) 2000-11-28
CZ249599A3 (cs) 2000-01-12
EP0961611A2 (de) 1999-12-08

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Legal Events

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HFG4 Patent granted, date of granting

Effective date: 20050509

MM4A Lapse of definitive patent protection due to non-payment of fees