BR9912979B1 - composição farmacêutica administrável oralmente, tablete de mascar, cápsula e uso de chitosan. - Google Patents

composição farmacêutica administrável oralmente, tablete de mascar, cápsula e uso de chitosan.

Info

Publication number
BR9912979B1
BR9912979B1 BRPI9912979-5A BR9912979A BR9912979B1 BR 9912979 B1 BR9912979 B1 BR 9912979B1 BR 9912979 A BR9912979 A BR 9912979A BR 9912979 B1 BR9912979 B1 BR 9912979B1
Authority
BR
Brazil
Prior art keywords
chitosan
capsule
pharmaceutical composition
orally administrable
administrable pharmaceutical
Prior art date
Application number
BRPI9912979-5A
Other languages
English (en)
Other versions
BR9912979A (pt
Inventor
Jacques Bailly
Andre Fleury
Paul Hadvary
Hans Lengsfeld
Hans Steffen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BR9912979A publication Critical patent/BR9912979A/pt
Publication of BR9912979B1 publication Critical patent/BR9912979B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007Effervescent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Epoxy Compounds (AREA)
BRPI9912979-5A 1998-08-14 1999-08-06 composição farmacêutica administrável oralmente, tablete de mascar, cápsula e uso de chitosan. BR9912979B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98115310 1998-08-14
EP99109430 1999-05-11
PCT/EP1999/005693 WO2000009123A1 (en) 1998-08-14 1999-08-06 Pharmaceutical compositions containing lipase inhibitors and chitosan

Publications (2)

Publication Number Publication Date
BR9912979A BR9912979A (pt) 2001-05-08
BR9912979B1 true BR9912979B1 (pt) 2010-09-21

Family

ID=26149536

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9912979-5A BR9912979B1 (pt) 1998-08-14 1999-08-06 composição farmacêutica administrável oralmente, tablete de mascar, cápsula e uso de chitosan.

Country Status (20)

Country Link
US (1) US6030953A (pt)
EP (1) EP1105123B1 (pt)
JP (1) JP3761783B2 (pt)
KR (1) KR20010079636A (pt)
CN (1) CN1152680C (pt)
AR (1) AR034691A1 (pt)
AT (1) ATE263558T1 (pt)
AU (1) AU759388B2 (pt)
BR (1) BR9912979B1 (pt)
CA (1) CA2340052C (pt)
CO (1) CO5160286A1 (pt)
DE (1) DE69916288T2 (pt)
DK (1) DK1105123T3 (pt)
ES (1) ES2217797T3 (pt)
MA (1) MA26672A1 (pt)
PE (1) PE20000954A1 (pt)
PT (1) PT1105123E (pt)
TR (1) TR200100472T2 (pt)
WO (1) WO2000009123A1 (pt)
ZA (1) ZA200100690B (pt)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6264937B1 (en) * 1998-01-09 2001-07-24 Geltex Pharmaceuticals, Inc. Fat-binding polymers
US7048917B1 (en) 1998-01-09 2006-05-23 Genzyme Corporation Fat-binding polymers
US6299868B1 (en) 1999-07-14 2001-10-09 Geltex Pharmaceuticals, Inc. Fat-binding polymers
CN1152680C (zh) * 1998-08-14 2004-06-09 霍夫曼-拉罗奇有限公司 含有脂酶抑制剂和壳聚糖的药物组合物
WO2000013667A1 (en) 1998-09-08 2000-03-16 Smithkline Beecham Corporation Lipstatin derivative-soluble fiber tablets
AR025609A1 (es) * 1999-09-13 2002-12-04 Hoffmann La Roche Formulaciones lipidas solidas
AR025587A1 (es) 1999-09-13 2002-12-04 Hoffmann La Roche Formulaciones en dispersion que contienen inhibidores de lipasa
US6235305B1 (en) * 1999-10-29 2001-05-22 2Pro Chemical Essentially nonabsorbable lipase inhibitor derivatives, pharmaceutical compositions and methods of use therefor
EP1132389A1 (en) 2000-03-06 2001-09-12 Vernalis Research Limited New aza-indolyl derivatives for the treatment of obesity
FI20000780A (fi) * 2000-04-03 2001-10-04 Novasso Oy Peroraalinen lääkemuoto lääkeaineen hallituksi vapauttamiseksi
EP1142572A1 (de) * 2000-04-04 2001-10-10 Volker Dr. Helmstädter Oxetanon-enthaltende Präparate zur Behandlung von Darmerkrankungen
JP4549486B2 (ja) * 2000-04-26 2010-09-22 アピ株式会社 抗肥満薬及びその製造方法
AU8184601A (en) 2000-06-27 2002-01-08 Hoffmann La Roche Method for preparing a composition
RU2241462C2 (ru) * 2000-07-28 2004-12-10 Ф. Хоффманн-Ля Рош Аг Новая фармацевтическая композиция
CN1261094C (zh) 2000-07-28 2006-06-28 霍夫曼-拉罗奇有限公司 脂肪酶抑制剂的新用途
EP1311260B1 (en) 2000-08-09 2008-04-02 F. Hoffmann-La Roche Ag Lipase inhibitors to treat dyspepsia
US6900226B2 (en) 2000-09-06 2005-05-31 Hoffman-La Roche Inc. Neuropeptide Y antagonists
US6251421B1 (en) * 2000-09-25 2001-06-26 Sarfaraz K. Niazi Pharmaceutical composition containing psyllium fiber and a lipase inhibitor
JP4047723B2 (ja) 2000-10-16 2008-02-13 エフ.ホフマン−ラ ロシュ アーゲー インドリン誘導体、および5−ht2受容体リガンドとしてのその使用
GB0030710D0 (en) 2000-12-15 2001-01-31 Hoffmann La Roche Piperazine derivatives
JP4094950B2 (ja) 2000-12-27 2008-06-04 エフ.ホフマン−ラ ロシュ アーゲー インドール誘導体および5−ht2bおよび5−ht2c受容体リガンドとしてのそれらの使用
GB0106177D0 (en) 2001-03-13 2001-05-02 Hoffmann La Roche Piperazine derivatives
US20030072804A1 (en) * 2001-03-19 2003-04-17 The Procter & Gamble Company Use of non-digestible polymeric foams to sequester ingested materials thereby inhibiting their absorption by the body
US20030091610A1 (en) * 2001-03-19 2003-05-15 The Procter & Gamble Company Use of non-digestible polymeric foams to sequester ingested materials thereby inhibiting their absorption by the body
DE60225274T2 (de) 2001-05-21 2009-03-26 F. Hoffmann-La Roche Ag Chinolinderivate als liganden für den neuropeptid-y-rezeptor
JP2004529363A (ja) * 2001-06-05 2004-09-24 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア 膵臓に基づく脂肪吸収不良障害を診断するための方法およびキット
US20030027786A1 (en) 2001-06-06 2003-02-06 Karsten Maeder Lipase inhibiting composition
US7041280B2 (en) * 2001-06-29 2006-05-09 Genzyme Corporation Aryl boronate functionalized polymers for treating obesity
US7049345B2 (en) * 2001-06-29 2006-05-23 Genzyme Corporation Fat-binding polymers
US6787558B2 (en) 2001-09-28 2004-09-07 Hoffmann-La Roche Inc. Quinoline derivatives
GB0202015D0 (en) 2002-01-29 2002-03-13 Hoffmann La Roche Piperazine Derivatives
JP4216196B2 (ja) 2002-02-04 2009-01-28 エフ.ホフマン−ラ ロシュ アーゲー Npyアンタゴニストとしてのキノリン誘導体
US20040091450A1 (en) * 2002-02-26 2004-05-13 The Procter & Gamble Company Use of non-digestible polymeric foams to sequester ingested materials thereby inhibiting their absorption by the body
WO2003072577A1 (en) 2002-02-28 2003-09-04 F.Hoffmann-La Roche Ag Thiazole derivatives as npy receptor antagonists
JP4234017B2 (ja) 2002-04-26 2009-03-04 エフ.ホフマン−ラ ロシュ アーゲー リパーゼ阻害薬及びグルコマンナンを含む医薬組成物
PL374817A1 (en) 2002-07-05 2005-10-31 F.Hoffmann-La Roche Ag Quinazoline derivatives
CN100381429C (zh) 2002-08-07 2008-04-16 霍夫曼-拉罗奇有限公司 噻唑衍生物
ES2209632B1 (es) * 2002-08-30 2005-08-01 Romildo Holding, N.V. Complemento dietetico, soluble, efervescente y alimenticio.
ATE345340T1 (de) 2002-09-12 2006-12-15 Hoffmann La Roche N-substituierte-1h-indol-5-propansäure verbindungen als ppar-agonisten zur behandlung von diabetis
DE10248575A1 (de) * 2002-10-17 2004-05-06 Christian-Albrechts-Universität Zu Kiel Chiltosanpellets
RU2315767C2 (ru) 2002-11-25 2008-01-27 Ф.Хоффманн-Ля Рош Аг Индолилпроизводные, способ их получения, фармацевтическая композиция, способ лечения и/или профилактики заболеваний
US8372430B2 (en) * 2002-12-17 2013-02-12 The Procter & Gamble Company Compositions, methods, and kits useful for the alleviation of gastrointestinal effects
GB0310919D0 (en) * 2003-05-13 2003-06-18 West Pharm Serv Drug Res Ltd Pharmaceutical compositions
GB0314967D0 (en) 2003-06-26 2003-07-30 Hoffmann La Roche Piperazine derivatives
US20050008699A1 (en) * 2003-07-11 2005-01-13 Fred Wehling Effervescent glucosamine composition
JP2007501824A (ja) 2003-08-12 2007-02-01 エフ.ホフマン−ラ ロシュ アーゲー Npyアンタゴニストとしてのチアゾール誘導体
MXPA06001570A (es) 2003-08-12 2006-05-15 Hoffmann La Roche Antagonistas del receptor de neuropeptido y (npy) 2-amino-5-benzoiltiazol.
US20080075688A1 (en) * 2003-10-31 2008-03-27 The Procter & Gamble Company Use of non-digestible polymeric foams to sequester ingested materials thereby inhibiting their absorption by the body
JP2005154477A (ja) * 2003-11-20 2005-06-16 Tottori Univ 紫外線硬化型キトサン誘導体を用いた医療用接着剤および医療用被覆剤
CA2560667A1 (en) * 2004-03-23 2005-11-03 Lytone Enterprise, Inc. Chitosan embedded or encapsulated capsule
US7465417B2 (en) * 2004-07-19 2008-12-16 Baxter International Inc. Parametric injection molding system and method
MXPA04010692A (es) * 2004-10-28 2006-05-02 Jorge Luis Rosado Loria Composicion para el tratamiento de la obesidad e hiperlipidemia.
ITMI20050150A1 (it) * 2005-02-03 2006-08-04 Umberto Cornelli Prodotti alimentari
JP2008540368A (ja) 2005-05-03 2008-11-20 エフ.ホフマン−ラ ロシュ アーゲー 5−ht2リガンドとしての四環式アザピラジノインドリン
WO2007020213A2 (en) 2005-08-18 2007-02-22 F. Hoffmann-La Roche Ag Thiazolyl piperidine derivatives useful as h3 receptor modulators
DE602006014022D1 (de) 2005-11-30 2010-06-10 Hoffmann La Roche 5-substituierte indol-2-carbonsäureamidderivate
CN101316840B (zh) 2005-11-30 2012-08-08 霍夫曼-拉罗奇有限公司 1,5-取代的吲哚-2-基酰胺衍生物
CN101316838B (zh) 2005-11-30 2013-01-30 霍夫曼-拉罗奇有限公司 用作h3调节剂的1,1-二氧代-硫代吗啉基吲哚基甲酮衍生物
CA2631128A1 (en) 2005-12-09 2007-06-14 F. Hoffmann-La Roche Ag Tricyclic amide derivatives useful for treating obesity
BRPI0619989A2 (pt) 2005-12-15 2011-10-25 Hoffmann La Roche Compostos, processo para a sua manufatura, composições farmacêuticas que os compreendem, métodos para o tratamento e/ou prevenção de enfermidades que estão associados com a modulação de receptores de h3, de obesidade e de diabetes do tipo ii em um ser humano ou animal e usos dos compostos
CN101331131A (zh) 2005-12-16 2008-12-24 霍夫曼-拉罗奇有限公司 用作H3受体调节剂的吡咯并[2,3-b]吡啶衍生物
ITMI20060384A1 (it) * 2006-03-03 2007-09-04 Umberto Cornelli Composizioni comprendenti chitosano atte al trattamento terapeutico complessivo o alla prevenzione complessiva della sindrome metabolica
KR101252635B1 (ko) 2006-04-20 2013-04-10 (주)아모레퍼시픽 리파아제 저해제 및 친유성 오일흡수제를 포함하는 약학조성물 및 이로부터 제조된 경구 투여용 제제
US7432255B2 (en) 2006-05-16 2008-10-07 Hoffmann-La Roche Inc. 1H-indol-5-yl-piperazin-1-yl-methanone derivatives
AU2007267184A1 (en) 2006-05-30 2007-12-06 F. Hoffmann-La Roche Ag Piperidinyl pyrimidine derivatives
US7514433B2 (en) 2006-08-03 2009-04-07 Hoffmann-La Roche Inc. 1H-indole-6-yl-piperazin-1-yl-methanone derivatives
US20080146559A1 (en) 2006-12-08 2008-06-19 Li Chen 4,5,6,7-Tetrahydro-Thieno [2,3-C] Pyridine Derivatives
TR200607613A2 (tr) * 2006-12-29 2008-07-21 NOBEL İLAÇ SAN.ve TiC.A.Ş. Lipaz inhibitörü içeren farmasötik formülasyonlar
EP2016946B1 (en) * 2007-07-18 2013-02-27 The Jordanian Pharmaceutical Manufacturing Co. Chitosan silicon dioxide coprecipitate composition for use as a therapeutically active agent
KR20100027231A (ko) 2007-07-25 2010-03-10 에프. 호프만-라 로슈 아게 벤조퓨란- 및 벤조[b]티오펜-2-카복실산 아마이드 유도체 및 이의 히스타민 3 수용체 조절제로서의 용도
WO2012070702A1 (ko) * 2010-11-25 2012-05-31 주식회사 삼양사 올리스태트 및 키토산 함유 조성물 및 그 제조방법
CN104546768B (zh) * 2014-12-30 2017-06-16 重庆植恩药业有限公司 含有脂肪酶抑制剂的咀嚼片组合物及其制备方法
CN105520947B (zh) * 2015-12-24 2018-05-01 广东药科大学 一种含有氨基葡萄糖的具有减肥功能的药物组合物
JOP20180128A1 (ar) * 2018-12-24 2020-06-24 Univ Of Petra صيغة دوائية صلبة قابلة للتشتت في الفم
GB202212379D0 (en) * 2022-08-25 2022-10-12 GlaxoSmithKline Consumer Healthcare UK IP Ltd Novel toothpaste tablet composition

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4223023A (en) * 1978-10-12 1980-09-16 Ivan Furda Nonabsorbable lipid binder
CA1247547A (en) * 1983-06-22 1988-12-28 Paul Hadvary Leucine derivatives
US5063210A (en) * 1989-04-20 1991-11-05 Lange Iii Louis G Use of sulfated polysaccharides to decrease cholesterol and fatty acid absorption
CA2098167C (en) * 1992-06-24 2006-12-19 Dorothea Isler Foodstuffs and feedstuffs containing a lipase inhibitor
CN1152680C (zh) * 1998-08-14 2004-06-09 霍夫曼-拉罗奇有限公司 含有脂酶抑制剂和壳聚糖的药物组合物

Also Published As

Publication number Publication date
AU5420599A (en) 2000-03-06
CA2340052A1 (en) 2000-02-24
PE20000954A1 (es) 2000-09-27
JP2002522492A (ja) 2002-07-23
PT1105123E (pt) 2004-08-31
CN1152680C (zh) 2004-06-09
WO2000009123A1 (en) 2000-02-24
ES2217797T3 (es) 2004-11-01
JP3761783B2 (ja) 2006-03-29
ZA200100690B (en) 2002-06-26
CA2340052C (en) 2007-05-29
EP1105123A1 (en) 2001-06-13
CN1312714A (zh) 2001-09-12
TR200100472T2 (tr) 2001-07-23
AR034691A1 (es) 2004-03-17
AU759388B2 (en) 2003-04-10
KR20010079636A (ko) 2001-08-22
ATE263558T1 (de) 2004-04-15
MA26672A1 (fr) 2004-12-20
CO5160286A1 (es) 2002-05-30
DK1105123T3 (da) 2004-08-09
DE69916288T2 (de) 2005-03-24
US6030953A (en) 2000-02-29
DE69916288D1 (de) 2004-05-13
EP1105123B1 (en) 2004-04-07
BR9912979A (pt) 2001-05-08

Similar Documents

Publication Publication Date Title
BR9912979B1 (pt) composição farmacêutica administrável oralmente, tablete de mascar, cápsula e uso de chitosan.
NO20020976D0 (no) Retarderte, orale, farmasöytiske administreringsformer
TR199901077A3 (tr) Ispençiyari formülasyonlar.
NO20001409L (no) Karboksamidotiazolderivater, fremgangsmÕte for fremstilling derav og farmasøytiske blandinger
FR2775596B1 (fr) Nouvelles compositions pharmaceutiques
IL148876A0 (en) Sulfonamide derivatives, their preparation and pharmaceutical compositions containing them
ZA200206905B (en) Azetidine derivatives, preparation thereof and pharmaceutical compositions containing same.
IL154965A0 (en) Sulfonamide derivatives, their preparation and pharmaceutical compositions containing them
ZA200007638B (en) Pyrazoline derivatives, their preparation and application as medicaments.
NO20014013D0 (no) 16-halogenepotilonderivater, fremgangsmater for fremstilling av dem og deres farmasoytiske anvendelse
DK1119557T3 (da) Indeno-, naphto- og benzocyclohepta-dihydrothiazolderivater, fremstilling deraf og anvendelse deraf som anorektiske medikamenter
BR9911871B1 (pt) derivados de ácido fenoxiacético e composições farmacêuticas contendo os mesmos.
HK1032958A1 (en) Derivatives of acyl-piperazinil-pyrimidins, preparation thereof and application as medicaments.
DK1112266T3 (da) Substituerede 4-amino-2-arylpyrimidiner, fremstilling og anvendelse deraf og farmaceutiske præparater indeholdende dem
NO20006138D0 (no) Substituerte indolinoner, fremstilling og anvendelse derav som medikamenter
HUP0105073A3 (en) 2-aminopyridine derivatives, their use as medicines and pharmaceutical compositions containing them
NO20022021D0 (no) Indeno-, nafto- og benzocyklohepta-dihydrotiazolderivater, fremstilling av de samme og deres anvendelse somanoreksilegemidler
DK1183026T3 (da) Forbedrede farmaceutiske formuleringer omfattende ritonavir
ZA200308221B (en) Pharmaceutical compositions for oral and topical administration.
FR2802423B1 (fr) Compositions pharmaceutiques
IS2258B (is) Setin tríasóló-pýridasín afleiða, lyfjasamsetningar gerðar úr henni
ZA200203294B (en) N-guanidinoalkylamides, their preparation, their use, and pharmaceutical preparations comprising them.
DZ1926A1 (fr) Formulations pharmaceutiques.
PT1131297E (pt) Certas caprolactamas substituidas composicoes farmaceuticas contendo-as e sua utilizacao no tratamento de tumores
IL154966A0 (en) Sulfonamide derivatives, their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 21/09/2010, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: REFERENTE A RPI 2072 DE 21/09/2010, CODIGO DO DESPACHO (16.1), ITEM (54) TITULO. ONDE SE LE: COMPOSICAO FARMACEUTICA ADMINISTRAVEL ORALMENTE, TABLETE DE MASCAR, CAPSULA E USO DE CHITOSAN. LEIA-SE: COMPOSICAO FARMACEUTICA ADMINISTRAVEL ORALMENTE, TABLETE DE MASCAR E CAPSULA PARA O TRATAMENTO DE OBESIDADE.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 21A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2595 DE 29-09-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.