PT1105123E - Composicoes farmaceuticas contendo inibidores da lipase e quitosano - Google Patents

Composicoes farmaceuticas contendo inibidores da lipase e quitosano

Info

Publication number
PT1105123E
PT1105123E PT99940161T PT99940161T PT1105123E PT 1105123 E PT1105123 E PT 1105123E PT 99940161 T PT99940161 T PT 99940161T PT 99940161 T PT99940161 T PT 99940161T PT 1105123 E PT1105123 E PT 1105123E
Authority
PT
Portugal
Prior art keywords
quitosane
inhibitors
pharmaceutical compositions
compositions containing
containing lipase
Prior art date
Application number
PT99940161T
Other languages
English (en)
Inventor
Jacques Bailly
Andre Fleury
Paul Hadvary
Hans Lengsfeld
Hans Steffen
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PT1105123E publication Critical patent/PT1105123E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Epoxy Compounds (AREA)
PT99940161T 1998-08-14 1999-08-06 Composicoes farmaceuticas contendo inibidores da lipase e quitosano PT1105123E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98115310 1998-08-14
EP99109430 1999-05-11

Publications (1)

Publication Number Publication Date
PT1105123E true PT1105123E (pt) 2004-08-31

Family

ID=26149536

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99940161T PT1105123E (pt) 1998-08-14 1999-08-06 Composicoes farmaceuticas contendo inibidores da lipase e quitosano

Country Status (20)

Country Link
US (1) US6030953A (pt)
EP (1) EP1105123B1 (pt)
JP (1) JP3761783B2 (pt)
KR (1) KR20010079636A (pt)
CN (1) CN1152680C (pt)
AR (1) AR034691A1 (pt)
AT (1) ATE263558T1 (pt)
AU (1) AU759388B2 (pt)
BR (1) BR9912979B1 (pt)
CA (1) CA2340052C (pt)
CO (1) CO5160286A1 (pt)
DE (1) DE69916288T2 (pt)
DK (1) DK1105123T3 (pt)
ES (1) ES2217797T3 (pt)
MA (1) MA26672A1 (pt)
PE (1) PE20000954A1 (pt)
PT (1) PT1105123E (pt)
TR (1) TR200100472T2 (pt)
WO (1) WO2000009123A1 (pt)
ZA (1) ZA200100690B (pt)

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AR025587A1 (es) 1999-09-13 2002-12-04 Hoffmann La Roche Formulaciones en dispersion que contienen inhibidores de lipasa
AR025609A1 (es) * 1999-09-13 2002-12-04 Hoffmann La Roche Formulaciones lipidas solidas
US6235305B1 (en) * 1999-10-29 2001-05-22 2Pro Chemical Essentially nonabsorbable lipase inhibitor derivatives, pharmaceutical compositions and methods of use therefor
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FI20000780A (fi) * 2000-04-03 2001-10-04 Novasso Oy Peroraalinen lääkemuoto lääkeaineen hallituksi vapauttamiseksi
EP1142572A1 (de) * 2000-04-04 2001-10-10 Volker Dr. Helmstädter Oxetanon-enthaltende Präparate zur Behandlung von Darmerkrankungen
JP4549486B2 (ja) * 2000-04-26 2010-09-22 アピ株式会社 抗肥満薬及びその製造方法
AU8184601A (en) 2000-06-27 2002-01-08 Hoffmann La Roche Method for preparing a composition
BR0112800A (pt) 2000-07-28 2003-07-01 Hoffmann La Roche Utilização de um inibidor de lìpases e de um sequestrante de ácido de bìlis farmaceuticamente aceitáveis e processo para a prevenção e tratamento de enfermidades associadas com altos nìveis de colesterol de plasma
IL154008A0 (en) 2000-07-28 2003-07-31 Hoffmann La Roche New pharmaceutical composition
AU1212002A (en) 2000-08-09 2002-02-18 Hoffmann La Roche Use of lipase inhibitors
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US20030091610A1 (en) * 2001-03-19 2003-05-15 The Procter & Gamble Company Use of non-digestible polymeric foams to sequester ingested materials thereby inhibiting their absorption by the body
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JP2004529363A (ja) * 2001-06-05 2004-09-24 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア 膵臓に基づく脂肪吸収不良障害を診断するための方法およびキット
US20030027786A1 (en) 2001-06-06 2003-02-06 Karsten Maeder Lipase inhibiting composition
US7041280B2 (en) * 2001-06-29 2006-05-09 Genzyme Corporation Aryl boronate functionalized polymers for treating obesity
US7049345B2 (en) * 2001-06-29 2006-05-23 Genzyme Corporation Fat-binding polymers
US6787558B2 (en) 2001-09-28 2004-09-07 Hoffmann-La Roche Inc. Quinoline derivatives
GB0202015D0 (en) 2002-01-29 2002-03-13 Hoffmann La Roche Piperazine Derivatives
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US20040091450A1 (en) * 2002-02-26 2004-05-13 The Procter & Gamble Company Use of non-digestible polymeric foams to sequester ingested materials thereby inhibiting their absorption by the body
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ATE453390T1 (de) * 2002-04-26 2010-01-15 Hoffmann La Roche Pharmazeutische zusammensetzung enthaltend einen lipase - inhibitor und glucomannan
KR100647932B1 (ko) 2002-07-05 2006-11-23 에프. 호프만-라 로슈 아게 퀴나졸린 유도체
WO2004014884A1 (en) 2002-08-07 2004-02-19 F. Hoffmann-La Roche Ag Thiazole derivatives
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RU2296759C2 (ru) 2002-09-12 2007-04-10 Ф.Хоффманн-Ля Рош Аг N-замещенные 1н-индол-5-пропионовые кислоты, фармацевтическая композиция, содержащая эти соединения, и их применение (варианты)
DE10248575A1 (de) * 2002-10-17 2004-05-06 Christian-Albrechts-Universität Zu Kiel Chiltosanpellets
MXPA05005445A (es) 2002-11-25 2005-08-26 Hoffmann La Roche Derivados de indolilo.
US8372430B2 (en) * 2002-12-17 2013-02-12 The Procter & Gamble Company Compositions, methods, and kits useful for the alleviation of gastrointestinal effects
GB0310919D0 (en) * 2003-05-13 2003-06-18 West Pharm Serv Drug Res Ltd Pharmaceutical compositions
GB0314967D0 (en) 2003-06-26 2003-07-30 Hoffmann La Roche Piperazine derivatives
US20050008699A1 (en) * 2003-07-11 2005-01-13 Fred Wehling Effervescent glucosamine composition
WO2005014593A1 (en) 2003-08-12 2005-02-17 F. Hoffmann-La Roche Ag Thiazole derivatives as npy antagonists
BRPI0413500A (pt) 2003-08-12 2006-10-10 Hoffmann La Roche compostos, processos para a sua preparação, composição farmacêutica que compreende os mesmos, utilização de um composto, métodos para o tratamento e profilaxia de artrite, diabetes, distúrbios alimentares e obesidade
US20080075688A1 (en) * 2003-10-31 2008-03-27 The Procter & Gamble Company Use of non-digestible polymeric foams to sequester ingested materials thereby inhibiting their absorption by the body
JP2005154477A (ja) * 2003-11-20 2005-06-16 Tottori Univ 紫外線硬化型キトサン誘導体を用いた医療用接着剤および医療用被覆剤
CN100496468C (zh) * 2004-03-23 2009-06-10 利统股份有限公司 甲壳素包埋或包胶胶囊
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JP2009517434A (ja) 2005-11-30 2009-04-30 エフ．ホフマン−ラ ロシュ アーゲー ５−置換インドール−２−カルボキサミド誘導体
KR101047204B1 (ko) 2005-11-30 2011-07-06 에프. 호프만-라 로슈 아게 Ｈ3 조절제로서 사용하기 위한1,1-다이옥소-싸이오모폴린일 인돌일 메탄온 유도체
KR101124156B1 (ko) 2005-11-30 2012-03-23 에프. 호프만-라 로슈 아게 1,5-치환된 인돌-2-일 아마이드 유도체
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JP2009519290A (ja) 2005-12-15 2009-05-14 エフ．ホフマン−ラ ロシュ アーゲー ピロロ［２，３−ｃ］ピリジン誘導体
BRPI0619985A2 (pt) 2005-12-16 2011-10-25 Hoffmann La Roche compostos, processo para a sua manufatura, composições farmacêuticas, métodos para o tratamento e/ou prevenção de enfermidades que estão associadas com a modulação de receptores de h3, de obesidade e de diabetes do tipo ii em um ser humano ou animal e usos dos compostos
ITMI20060384A1 (it) * 2006-03-03 2007-09-04 Umberto Cornelli Composizioni comprendenti chitosano atte al trattamento terapeutico complessivo o alla prevenzione complessiva della sindrome metabolica
KR101252635B1 (ko) 2006-04-20 2013-04-10 (주)아모레퍼시픽 리파아제 저해제 및 친유성 오일흡수제를 포함하는 약학조성물 및 이로부터 제조된 경구 투여용 제제
US7432255B2 (en) 2006-05-16 2008-10-07 Hoffmann-La Roche Inc. 1H-indol-5-yl-piperazin-1-yl-methanone derivatives
US7902184B2 (en) 2006-05-30 2011-03-08 Hoffmann-La Roche Inc. Piperazinyl pyrimidine derivatives
US7514433B2 (en) 2006-08-03 2009-04-07 Hoffmann-La Roche Inc. 1H-indole-6-yl-piperazin-1-yl-methanone derivatives
US20080146559A1 (en) 2006-12-08 2008-06-19 Li Chen 4,5,6,7-Tetrahydro-Thieno [2,3-C] Pyridine Derivatives
TR200607613A2 (tr) * 2006-12-29 2008-07-21 NOBEL İLAÇ SAN.ve TiC.A.Ş. Lipaz inhibitörü içeren farmasötik formülasyonlar
EP2016946B1 (en) * 2007-07-18 2013-02-27 The Jordanian Pharmaceutical Manufacturing Co. Chitosan silicon dioxide coprecipitate composition for use as a therapeutically active agent
KR20100027231A (ko) 2007-07-25 2010-03-10 에프. 호프만-라 로슈 아게 벤조퓨란- 및 벤조[ｂ]티오펜-2-카복실산 아마이드 유도체 및 이의 히스타민 3 수용체 조절제로서의 용도
WO2012070702A1 (ko) * 2010-11-25 2012-05-31 주식회사 삼양사 올리스태트 및 키토산 함유 조성물 및 그 제조방법
CN104546768B (zh) * 2014-12-30 2017-06-16 重庆植恩药业有限公司 含有脂肪酶抑制剂的咀嚼片组合物及其制备方法
CN105520947B (zh) * 2015-12-24 2018-05-01 广东药科大学 一种含有氨基葡萄糖的具有减肥功能的药物组合物
JOP20180128A1 (ar) * 2018-12-24 2020-06-24 Univ Of Petra صيغة دوائية صلبة قابلة للتشتت في الفم
GB202212379D0 (en) * 2022-08-25 2022-10-12 GlaxoSmithKline Consumer Healthcare UK IP Ltd Novel toothpaste tablet composition

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Also Published As

Publication number Publication date
BR9912979B1 (pt) 2010-09-21
ATE263558T1 (de) 2004-04-15
CN1152680C (zh) 2004-06-09
AR034691A1 (es) 2004-03-17
AU759388B2 (en) 2003-04-10
PE20000954A1 (es) 2000-09-27
AU5420599A (en) 2000-03-06
CN1312714A (zh) 2001-09-12
BR9912979A (pt) 2001-05-08
KR20010079636A (ko) 2001-08-22
JP3761783B2 (ja) 2006-03-29
ES2217797T3 (es) 2004-11-01
EP1105123B1 (en) 2004-04-07
TR200100472T2 (tr) 2001-07-23
US6030953A (en) 2000-02-29
WO2000009123A1 (en) 2000-02-24
CA2340052C (en) 2007-05-29
EP1105123A1 (en) 2001-06-13
CA2340052A1 (en) 2000-02-24
CO5160286A1 (es) 2002-05-30
DE69916288T2 (de) 2005-03-24
JP2002522492A (ja) 2002-07-23
MA26672A1 (fr) 2004-12-20
ZA200100690B (en) 2002-06-26
DE69916288D1 (de) 2004-05-13
DK1105123T3 (da) 2004-08-09

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