HUE042044T2 - Elektroporációs készülékek sejtek elektroporációjára emlõsökben - Google Patents

Elektroporációs készülékek sejtek elektroporációjára emlõsökben

Info

Publication number
HUE042044T2
HUE042044T2 HUE11184546A HUE11184546A HUE042044T2 HU E042044 T2 HUE042044 T2 HU E042044T2 HU E11184546 A HUE11184546 A HU E11184546A HU E11184546 A HUE11184546 A HU E11184546A HU E042044 T2 HUE042044 T2 HU E042044T2
Authority
HU
Hungary
Prior art keywords
electroporation
mammals
cells
devices
electroporation devices
Prior art date
Application number
HUE11184546A
Other languages
English (en)
Hungarian (hu)
Inventor
Patricia A Brown
Ruxandra Draghia-Akli
Amir Khan
Melissa A Pope
Original Assignee
Inovio Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inovio Pharmaceuticals Inc filed Critical Inovio Pharmaceuticals Inc
Publication of HUE042044T2 publication Critical patent/HUE042044T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0412Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0476Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
HUE11184546A 2006-10-17 2007-10-17 Elektroporációs készülékek sejtek elektroporációjára emlõsökben HUE042044T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85214906P 2006-10-17 2006-10-17
US97898207P 2007-10-10 2007-10-10

Publications (1)

Publication Number Publication Date
HUE042044T2 true HUE042044T2 (hu) 2019-06-28

Family

ID=38935920

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE18198349A HUE069139T2 (hu) 2006-10-17 2007-10-17 Elektroporációs eszközök sejtek elektroporálására emlõsökben
HUE11184546A HUE042044T2 (hu) 2006-10-17 2007-10-17 Elektroporációs készülékek sejtek elektroporációjára emlõsökben

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HUE18198349A HUE069139T2 (hu) 2006-10-17 2007-10-17 Elektroporációs eszközök sejtek elektroporálására emlõsökben

Country Status (16)

Country Link
US (1) US9452285B2 (enExample)
EP (4) EP2066399B1 (enExample)
JP (1) JP5439183B2 (enExample)
KR (1) KR101421760B1 (enExample)
CN (1) CN105457157B (enExample)
AU (1) AU2007313203B2 (enExample)
CA (1) CA2666501C (enExample)
DK (2) DK3524316T3 (enExample)
ES (2) ES2703744T3 (enExample)
FI (1) FI3524316T3 (enExample)
HU (2) HUE069139T2 (enExample)
LT (1) LT3524316T (enExample)
PL (2) PL3524316T3 (enExample)
PT (2) PT2066399T (enExample)
SG (1) SG175627A1 (enExample)
WO (1) WO2008048632A1 (enExample)

Families Citing this family (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9037230B2 (en) 2006-03-03 2015-05-19 Oncosec Medical Incorporated Method and device for treating microscopic tumors remaining in tissues following surgical resection
US7687267B2 (en) * 2006-09-30 2010-03-30 Rational Biotechnology Inc. High-throughput cell transfection device and methods of using thereof
WO2009073330A2 (en) 2007-11-12 2009-06-11 The Trustees Of The University Of Pennsylvania Novel vaccines against multiple subtypes of influenza virus
US8927508B2 (en) * 2007-11-14 2015-01-06 Vgx Pharmaceuticals, Inc. Antibody production elicited by a DNA vaccine delivered by electroporation
KR101589511B1 (ko) * 2008-04-04 2016-02-01 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 치쿤구니야 바이러스 단백질의 공통 서열, 이를 인코딩하는 핵산 분자, 조성물 및 이를 이용하는 방법
CN105535961A (zh) 2008-04-04 2016-05-04 宾夕法尼亚大学托管会 使用il-28和组合物的疫苗和免疫治疗及其使用方法
ITCO20080016A1 (it) * 2008-04-22 2009-10-23 Giuseppe Caccia Manipolo per elettroporazione di prodotti farmacologici e/o naturali e/o estetici su strati cutanei a spessore contenuto
US8829174B2 (en) 2008-10-29 2014-09-09 The Trustees Of The University Of Pennsylvania HCV vaccines and methods for using the same
US8921536B2 (en) 2008-10-29 2014-12-30 The Trustees Of The University Of Pennsylvania HCV vaccines and methods for using the same
KR101667069B1 (ko) * 2008-11-17 2016-10-17 이노비오 파마수티컬즈, 인크. 플라비바이러스에 대한 면역반응을 유발하는 항원 및 이를 사용하는 방법
US8632534B2 (en) 2009-04-03 2014-01-21 Angiodynamics, Inc. Irreversible electroporation (IRE) for congestive obstructive pulmonary disease (COPD)
KR102697118B1 (ko) 2009-04-16 2024-08-22 이노비오 파마수티컬즈, 인크. 비접촉식 전기천공 전극 및 방법
US8903488B2 (en) 2009-05-28 2014-12-02 Angiodynamics, Inc. System and method for synchronizing energy delivery to the cardiac rhythm
US9895189B2 (en) 2009-06-19 2018-02-20 Angiodynamics, Inc. Methods of sterilization and treating infection using irreversible electroporation
WO2011050009A1 (en) * 2009-10-19 2011-04-28 Rational Biotechnology Inc. Method, device and apparatus for inducing self-adjusting cell electroporation
US8298820B2 (en) 2010-01-26 2012-10-30 The Trustees Of The University Of Pennsylvania Influenza nucleic acid molecules and vaccines made therefrom
AU2011223768B2 (en) * 2010-03-01 2014-10-30 Inovio Pharmaceuticals, Inc. Multiple tissue layer electroporation applicator and device
EP2627274B1 (en) 2010-10-13 2022-12-14 AngioDynamics, Inc. System for electrically ablating tissue of a patient
CA3042411A1 (en) 2011-01-28 2012-08-02 The General Hospital Corporation Method and apparatus for skin resurfacing
EP2667805B1 (en) 2011-01-28 2023-04-05 The General Hospital Corporation Apparatus and method for tissue biopsy
MX349915B (es) 2011-01-28 2017-08-18 Massachusetts Gen Hospital Método y aparato para la dermoabrasión discontinua.
CA2826199A1 (en) 2011-01-31 2012-08-09 The Trustees Of The University Of Pennsylvania Nucleic acid molecules encoding novel herpes antigens, vaccine comprising the same, and methods of use thereof
KR101363000B1 (ko) * 2011-03-03 2014-02-24 라종주 피부 미용방법, 미용기 및 미용 시스템
ITTO20110374A1 (it) * 2011-04-29 2012-10-30 Igea S P A Metodo di controllo di un dispositivo di elettro-porazione
KR20140068000A (ko) 2011-06-15 2014-06-05 크론테크 파마 아베 주사 바늘 및 장치
DK3473296T3 (da) * 2011-06-28 2020-11-09 Inovio Pharmaceuticals Inc Minimalt invasiv dermal elektroporeringsenhed
AU2015203882C1 (en) * 2011-06-28 2017-09-21 Inovio Pharmaceuticals, Inc. A minimally invasive dermal electroporation device
CA2846229C (en) 2011-07-21 2019-08-27 The General Hospital Corporation Method and apparatus for damage and removal of fat
US9078665B2 (en) 2011-09-28 2015-07-14 Angiodynamics, Inc. Multiple treatment zone ablation probe
US9414881B2 (en) 2012-02-08 2016-08-16 Angiodynamics, Inc. System and method for increasing a target zone for electrical ablation
CN102680526B (zh) * 2012-05-16 2014-07-02 清华大学 单细胞阵列微芯片及其制造、电测量和电穿孔方法
KR101979746B1 (ko) * 2012-09-13 2019-05-17 (주)아모레퍼시픽 전기 천공 장치
US20140171957A1 (en) * 2012-12-19 2014-06-19 Alcon Research, Ltd. Control of Automated Intraocular Lens Injectors
CN107398013A (zh) * 2012-12-24 2017-11-28 电子运动医疗有限公司 用于唤起胃肠器官中连续的肌肉收缩的装置
US10543127B2 (en) 2013-02-20 2020-01-28 Cytrellis Biosystems, Inc. Methods and devices for skin tightening
WO2015021434A2 (en) 2013-08-09 2015-02-12 Cytrellis Biosystems, Inc. Methods and apparatuses for skin treatment using non-thermal tissue ablation
EP3082897A4 (en) 2013-12-19 2017-07-26 Cytrellis Biosystems, Inc. Methods and devices for manipulating subdermal fat
US11260137B2 (en) * 2014-04-06 2022-03-01 Emily Chen Tang Electroporation apparatuses and their method of use
US12114911B2 (en) * 2014-08-28 2024-10-15 Angiodynamics, Inc. System and method for ablating a tissue site by electroporation with real-time pulse monitoring
EP3217899A4 (en) 2014-11-14 2018-07-11 Cytrellis Biosystems, Inc. Devices and methods for ablation of the skin
WO2016161113A1 (en) * 2015-03-31 2016-10-06 University Of South Florida System and method for electroporation controlled by electrical impedance measurements
DK3277368T3 (da) * 2015-03-31 2020-07-27 Oncosec Medical Inc Systemer til forbedret vævsregistreringsbaseret elektroporering
EP4442300A3 (en) 2015-12-28 2024-12-25 Inovio Pharmaceuticals, Inc. Intradermal jet injection electroporation device
ITUB20159819A1 (it) * 2015-12-31 2017-07-01 Biopulse S R L Elettroporatore teranostico ad onda bifasica per la diagnosi delle aree patologiche ed il trasferimento terapeutico di molecole e relativo procedimento
WO2017136758A1 (en) 2016-02-05 2017-08-10 Inovio Pharmaceuticals, Inc. Cancer vaccines and methods of treatment using the same
JP6968867B2 (ja) 2016-03-29 2021-11-17 サイトレリス バイオシステムズ,インコーポレーテッド 美容用スキンリサーフェシングのためのデバイス及び方法
JP7250520B2 (ja) 2016-04-13 2023-04-03 ヤンセン ファーマシューティカルズ,インコーポレーテッド 組換えアルテリウイルスレプリコン系およびその使用
CN109922740B (zh) 2016-09-21 2022-08-23 希特利斯生物系统有限公司 用于美容皮肤重建的装置和方法
CN110073002B (zh) 2016-10-17 2024-06-11 杨森制药公司 重组病毒复制子体系及其用途
JP7158820B2 (ja) * 2016-10-26 2022-10-24 ロレアル エレクトロポレーションデバイスおよびエレクトロポレーションデバイスを制御するための方法
US10905492B2 (en) 2016-11-17 2021-02-02 Angiodynamics, Inc. Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode
CA3045650A1 (en) 2016-12-05 2018-06-14 Synthetic Genomics, Inc. Compositions and methods for enhancing gene expression
KR20180123312A (ko) * 2017-05-08 2018-11-16 (주)오스힐 미세전류 조절 수단을 구비한 스킨 부스터
JP6518971B2 (ja) * 2017-05-12 2019-05-29 株式会社ベックス エレクトロポレーター用電源
CN107126628A (zh) * 2017-06-14 2017-09-05 重庆百国智科技发展有限公司 一种人体电位差细胞补水及生物电信号修复的装置及其方法
DE102017116305A1 (de) * 2017-07-19 2019-01-24 Cinogy Gmbh Plasma-Behandlungsgerät
SE541651C2 (en) 2017-07-28 2019-11-19 Scandinavian Chemotech Ab An electrode device and a needle electrode for use in delivery of electrical pulses to a desired tissue of a mammal
BR112020010542A2 (pt) 2017-12-13 2020-12-01 Inovio Pharmaceuticals, Inc. moléculas de ácido nucleico, vetor, composição, proteínas, usos dos anteriores, e vacinas
BR112020011716A2 (pt) 2017-12-13 2020-11-17 Inovio Pharmaceuticals, Inc. molécula de ácido nucleico, seus usos, vetor, composição, proteína e vacina
MX2020006226A (es) 2017-12-13 2020-11-18 Inovio Pharmaceuticals Inc Vacunas contra el cancer dirigidas a mesotelina y usos de estas.
JP7317017B2 (ja) 2017-12-19 2023-07-28 ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー B型肝炎ウイルス(hbv)ワクチンおよびその使用
EA202091513A1 (ru) 2017-12-19 2020-09-09 Янссен Сайенсиз Айрлэнд Анлимитед Компани Вакцины против вируса гепатита b (hbv) и их применение
EA202091517A1 (ru) 2017-12-19 2020-11-03 Янссен Сайенсиз Айрлэнд Анлимитед Компани Способы и устройство для доставки вакцин против вируса гепатита b (hbv)
MX2020006471A (es) 2017-12-19 2020-09-22 Janssen Sciences Ireland Unlimited Co Metodos y composiciones para inducir una respuesta inmune contra el virus de hepatitis b (hbv).
EA202091516A1 (ru) 2017-12-19 2020-11-03 Янссен Сайенсиз Айрлэнд Анлимитед Компани Способы и композиции для индукции иммунного ответа против вируса гепатита b (hbv)
KR20200111729A (ko) 2018-01-19 2020-09-29 얀센 파마슈티칼즈, 인코포레이티드 재조합 레플리콘 시스템을 이용한 면역 반응 유도 및 증진
KR102132370B1 (ko) * 2018-03-13 2020-08-05 주식회사 지씨에스 피부관리장치, 피부관리장치의 구동방법 및 컴퓨터 판독가능 기록매체
CN112867786A (zh) * 2018-08-01 2021-05-28 俄亥俄州国家创新基金会 用于将皮肤重编程为产生胰岛素的组织的组合物和方法
US12331076B2 (en) 2018-10-08 2025-06-17 Janssen Pharmaceuticals, Inc. Alphavirus-based replicons for administration of biotherapeutics
EP3673846A1 (en) * 2018-12-27 2020-07-01 Bogdan Ionescu Device for an electrophysiology procedure
US11071860B2 (en) * 2019-02-06 2021-07-27 Oncosec Medical Incorporated Systems and methods for detecting fault conditions in electroporation therapy
MA56520A (fr) 2019-06-18 2022-04-27 Janssen Sciences Ireland Unlimited Co Construction de l'interleukine 12 recombinante et ses utilisations
US20220305115A1 (en) 2019-06-18 2022-09-29 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and pyridopyrimidine derivatives
CA3140707A1 (en) 2019-06-18 2020-12-24 Helen Horton Combination of hepatitis b virus (hbv) vaccines and quinazoline derivatives
WO2020255035A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and pyrimidine derivatives
WO2020255019A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and a quinazoline derivative
WO2020254876A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Virus-like particle delivery of hepatitis b virus (hbv) vaccines
WO2020255042A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and a pyrimidine derivative
WO2020255017A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and dihydropyrimidine derivatives as capsid assembly modulators
WO2020255007A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and hbv-targeting rnai
WO2020255010A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of recombinant interleukin 12 construct and hepatitis b virus (hbv) vaccines
WO2020255020A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and pd-l1 inhibitors
CA3143679A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and hbv-targeting rnai
WO2020255015A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and dihydropyrimidine derivatives as capsid assembly modulators
WO2020255022A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and aminopyridine derivatives as hpk1 inhibitors
WO2020255016A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and dihydropyrimidine derivatives as capsid assembly modulators
WO2020255011A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and anti-pd-1 or anti-pd-l1 antibody
CN114206379A (zh) 2019-06-18 2022-03-18 爱尔兰詹森科学公司 乙型肝炎病毒(hbv)疫苗和抗pd-1抗体的组合
CA3140588A1 (en) 2019-06-18 2020-12-24 Helen Horton Combination of hepatitis b virus (hbv) vaccines and small molecule pdl1 or pd1 inhibitor
WO2020255012A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and capsid assembly modulators being sulfonamide derivatives
US20220324916A1 (en) 2019-06-18 2022-10-13 Janssen Sciences Ireland Unlimited Company Hepatitis B Virus (HBV) Vaccines and Uses Thereof
WO2020255013A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and capsid assembly modulators being amide derivatives
AU2020297019A1 (en) 2019-06-20 2022-02-17 Janssen Sciences Ireland Unlimited Company Carbohydrate nanocarrier delivery of hepatitis B virus (HBV) vaccines
WO2020255062A1 (en) 2019-06-20 2020-12-24 Janssen Sciences Ireland Unlimited Company Lipid nanoparticle or liposome delivery of hepatitis b virus (hbv) vaccines
US20220290183A1 (en) * 2019-08-30 2022-09-15 Virginia Tech Intellectual Properties, Inc. Method for intracellular delivery of compounds using cell force and shape with electric fields
IL296163A (en) * 2020-03-20 2022-11-01 Inovio Pharmaceuticals Inc Vacuum-assisted electroporation devices, and related systems and methods
CN111581642A (zh) * 2020-05-03 2020-08-25 付贵龙 一种互联网安全防护系统
JP2023533174A (ja) 2020-06-12 2023-08-02 ユニバーシティ オブ ロチェスター ACE-tRNAのコード化及び発現
US12496442B2 (en) 2020-06-30 2025-12-16 Industrial Technology Research Institute Microneedle electroporation device
WO2022008613A1 (en) 2020-07-08 2022-01-13 Janssen Sciences Ireland Unlimited Company Rna replicon vaccines against hbv
US12006507B2 (en) 2020-07-22 2024-06-11 Nantcell, Inc. Electroporation with active compensation
US12076071B2 (en) 2020-08-14 2024-09-03 Kardium Inc. Systems and methods for treating tissue with pulsed field ablation
US20220071692A1 (en) * 2020-09-08 2022-03-10 Biosense Webster (Israel) Ltd. Impedance based irreversible-electroporation (ire)
TW202245809A (zh) 2020-12-18 2022-12-01 美商詹森藥物公司 用於治療b型肝炎病毒感染之組合療法
EP4267740A1 (en) 2020-12-28 2023-11-01 Arcturus Therapeutics, Inc. Transcription activator-like effector nucleases (talens) targeting hbv
EP4476348A1 (en) 2022-02-07 2024-12-18 University of Rochester Optimized sequences for enhanced trna expression or/and nonsense mutation suppression
AU2023224287A1 (en) * 2022-02-25 2024-10-03 Inovio Pharmaceuticals, Inc. Handheld electroporation devices, and related systems and methods
CA3252072A1 (en) * 2022-05-05 2023-11-09 Renbio, Inc. PLASMIC DNA CONSTRUCTIONS FOR THE EXPRESSION OF THERAPEUTIC PROTEINS
WO2023233290A1 (en) 2022-05-31 2023-12-07 Janssen Sciences Ireland Unlimited Company Rnai agents targeting pd-l1
EP4634373A1 (en) 2022-12-16 2025-10-22 University of Rochester Repairment of barrier dysfunction in esophagus
WO2025101685A1 (en) 2023-11-09 2025-05-15 University Of Rochester Suppression of nonsense mutations using anticodon engineered (ace)-trnas
CN120436779B (zh) * 2025-07-01 2025-09-30 北京航空航天大学青岛研究院 十二指肠粘膜表面置换与电转染一体化设备及基于参数反馈运行的方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989006555A1 (en) 1988-01-21 1989-07-27 Massachusetts Institute Of Technology Transport of molecules across tissue using electroporation
US5545130A (en) 1992-04-08 1996-08-13 Genetronics, Inc. Flow through electroporation method
US5702359A (en) 1995-06-06 1997-12-30 Genetronics, Inc. Needle electrodes for mediated delivery of drugs and genes
US5439440A (en) * 1993-04-01 1995-08-08 Genetronics, Inc. Electroporation system with voltage control feedback for clinical applications
US5869326A (en) 1996-09-09 1999-02-09 Genetronics, Inc. Electroporation employing user-configured pulsing scheme
US6241701B1 (en) 1997-08-01 2001-06-05 Genetronics, Inc. Apparatus for electroporation mediated delivery of drugs and genes
US6216034B1 (en) 1997-08-01 2001-04-10 Genetronics, Inc. Method of programming an array of needle electrodes for electroporation therapy of tissue
US6055453A (en) 1997-08-01 2000-04-25 Genetronics, Inc. Apparatus for addressing needle array electrodes for electroporation therapy
US6120493A (en) 1998-01-27 2000-09-19 Genetronics, Inc. Method for the introduction of therapeutic agents utilizing an electroporation apparatus
US6208893B1 (en) 1998-01-27 2001-03-27 Genetronics, Inc. Electroporation apparatus with connective electrode template
WO2000002621A1 (en) * 1998-07-13 2000-01-20 Genetronics, Inc. Skin and muscle-targeted gene therapy by pulsed electrical field
AU761522B2 (en) 1998-07-13 2003-06-05 Genetronics, Inc. Method and apparatus for electrically assisted topical delivery of agents for cosmetic applications
US6972013B1 (en) * 1998-07-13 2005-12-06 Genetronics, Inc. Enhanced delivery of naked DNA to skin by non-invasive in vivo electroporation
US6192270B1 (en) 1998-08-14 2001-02-20 Genetronics, Inc. Apparatus and method for the delivery of drugs and genes into tissue
US6150148A (en) 1998-10-21 2000-11-21 Genetronics, Inc. Electroporation apparatus for control of temperature during the process
US6148232A (en) * 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US7171264B1 (en) * 1999-05-10 2007-01-30 Genetronics, Inc. Intradermal delivery of active agents by needle-free injection and electroporation
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6300108B1 (en) * 1999-07-21 2001-10-09 The Regents Of The University Of California Controlled electroporation and mass transfer across cell membranes
WO2001089455A2 (en) * 2000-05-22 2001-11-29 Merck & Company, Inc. System and method for assessing the performance of a pharmaceutical agent delivery system
CN1345610A (zh) * 2000-09-30 2002-04-24 杭州泰士生物科技有限公司 一种活体组织电穿孔用的波形及波形发生器
JP3543326B2 (ja) 2001-08-30 2004-07-14 ソニー株式会社 情報処理装置および方法、情報処理システム、情報配信装置、記録媒体、並びにプログラム
US8209006B2 (en) 2002-03-07 2012-06-26 Vgx Pharmaceuticals, Inc. Constant current electroporation device and methods of use
US7245963B2 (en) 2002-03-07 2007-07-17 Advisys, Inc. Electrode assembly for constant-current electroporation and use
US20080269153A1 (en) * 2002-05-28 2008-10-30 Ruxandra Draghia-Akli Increased stability of a dna formulation by including poly-l-glutamate
US7328064B2 (en) * 2002-07-04 2008-02-05 Inovio As Electroporation device and injection apparatus
US20050070841A1 (en) 2002-07-04 2005-03-31 Inovio As Electroporation device and injection apparatus
DK2364769T3 (en) 2003-05-30 2016-04-11 Vgxi Inc Apparatus and methods for biomaterialeproduktion

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EP4477254A3 (en) 2025-02-19
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WO2008048632A1 (en) 2008-04-24
EP2066399B1 (en) 2018-10-03
CA2666501C (en) 2017-03-21
ES2993941T3 (en) 2025-01-14
CN105457157B (zh) 2020-04-14
DK3524316T3 (da) 2024-11-11
EP3524316B1 (en) 2024-08-07
EP2066399A1 (en) 2009-06-10
LT3524316T (lt) 2024-11-25
EP4477254A2 (en) 2024-12-18
PL2409727T3 (pl) 2019-03-29
EP2409727A1 (en) 2012-01-25
HUE069139T2 (hu) 2025-02-28
ES2703744T3 (es) 2019-03-12
CN105457157A (zh) 2016-04-06
EP3524316A1 (en) 2019-08-14
AU2007313203B2 (en) 2012-08-16
PT3524316T (pt) 2024-11-29
FI3524316T3 (fi) 2024-11-08
AU2007313203A1 (en) 2008-04-24
CA2666501A1 (en) 2008-04-24
KR101421760B1 (ko) 2014-07-22
PL3524316T3 (pl) 2024-12-23
DK2066399T3 (en) 2019-01-21
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US9452285B2 (en) 2016-09-27
JP2010506660A (ja) 2010-03-04
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