CN105457157B - 电穿孔装置及用其进行哺乳动物细胞电穿孔的方法 - Google Patents

电穿孔装置及用其进行哺乳动物细胞电穿孔的方法 Download PDF

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Publication number
CN105457157B
CN105457157B CN201510716613.XA CN201510716613A CN105457157B CN 105457157 B CN105457157 B CN 105457157B CN 201510716613 A CN201510716613 A CN 201510716613A CN 105457157 B CN105457157 B CN 105457157B
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skin
electroporation
energy
pulse
electrodes
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CN105457157A (zh
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R.德雷希亚-阿克利
A.S.韩
M.A.波普
P.A.布朗
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Inovio Biopharmaceutical Co.
VGX Pharmaceutical Co.,Ltd.
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Inovio Pharmaceuticals Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0412Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0476Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
CN201510716613.XA 2006-10-17 2007-10-17 电穿孔装置及用其进行哺乳动物细胞电穿孔的方法 Active CN105457157B (zh)

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US85214906P 2006-10-17 2006-10-17
US60/852149 2006-10-17
US97898207P 2007-10-10 2007-10-10
US60/978982 2007-10-10
CNA2007800466527A CN101563132A (zh) 2006-10-17 2007-10-17 电穿孔装置及用其进行哺乳动物细胞电穿孔的方法

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CN105457157B true CN105457157B (zh) 2020-04-14

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EP (4) EP2066399B1 (enExample)
JP (1) JP5439183B2 (enExample)
KR (1) KR101421760B1 (enExample)
CN (1) CN105457157B (enExample)
AU (1) AU2007313203B2 (enExample)
CA (1) CA2666501C (enExample)
DK (2) DK2066399T3 (enExample)
ES (2) ES2993941T3 (enExample)
FI (1) FI3524316T3 (enExample)
HU (2) HUE042044T2 (enExample)
LT (1) LT3524316T (enExample)
PL (2) PL3524316T3 (enExample)
PT (2) PT3524316T (enExample)
SG (1) SG175627A1 (enExample)
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