HU227190B1 - Trpm-2 antisense therapy - Google Patents

Trpm-2 antisense therapy Download PDF

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Publication number
HU227190B1
HU227190B1 HU0200093A HUP0200093A HU227190B1 HU 227190 B1 HU227190 B1 HU 227190B1 HU 0200093 A HU0200093 A HU 0200093A HU P0200093 A HUP0200093 A HU P0200093A HU 227190 B1 HU227190 B1 HU 227190B1
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Hungary
Prior art keywords
trpm
antisense
seq
odn
composition
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HU0200093A
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English (en)
Hungarian (hu)
Inventor
Martin Gleave
Paul S Rennie
Hideaki Miyake
Colleen Nelson
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Univ British Columbia
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Publication date
Application filed by Univ British Columbia filed Critical Univ British Columbia
Publication of HUP0200093A2 publication Critical patent/HUP0200093A2/hu
Publication of HU227190B1 publication Critical patent/HU227190B1/hu

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
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    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/321—2'-O-R Modification
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    • C12N2310/30—Chemical structure
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    • C12N2310/341—Gapmers, i.e. of the type ===---===
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/34—Spatial arrangement of the modifications
    • C12N2310/346—Spatial arrangement of the modifications having a combination of backbone and sugar modifications

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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HU0200093A 1999-02-26 2000-02-25 Trpm-2 antisense therapy HU227190B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12172699P 1999-02-26 1999-02-26
PCT/US2000/004875 WO2000049937A2 (en) 1999-02-26 2000-02-25 Trpm-2 antisense therapy

Publications (2)

Publication Number Publication Date
HUP0200093A2 HUP0200093A2 (en) 2002-05-29
HU227190B1 true HU227190B1 (en) 2010-10-28

Family

ID=22398429

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0200093A HU227190B1 (en) 1999-02-26 2000-02-25 Trpm-2 antisense therapy

Country Status (15)

Country Link
US (7) US7534773B1 (https=)
EP (1) EP1163254B1 (https=)
JP (1) JP4785252B2 (https=)
KR (2) KR100768109B1 (https=)
AT (1) ATE385237T1 (https=)
AU (1) AU767133B2 (https=)
CA (2) CA2850318A1 (https=)
DE (1) DE60037938T2 (https=)
DK (1) DK1163254T3 (https=)
ES (1) ES2300257T3 (https=)
HU (1) HU227190B1 (https=)
IL (2) IL144975A0 (https=)
NO (1) NO330799B1 (https=)
NZ (1) NZ513757A (https=)
WO (1) WO2000049937A2 (https=)

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