HU190774B - Process for preparing ether derivatives with pharmacological activity - Google Patents
Process for preparing ether derivatives with pharmacological activity Download PDFInfo
- Publication number
- HU190774B HU190774B HU801601A HU160180A HU190774B HU 190774 B HU190774 B HU 190774B HU 801601 A HU801601 A HU 801601A HU 160180 A HU160180 A HU 160180A HU 190774 B HU190774 B HU 190774B
- Authority
- HU
- Hungary
- Prior art keywords
- formula
- group
- formyl
- compound
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/30—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing —CHO groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/74—Unsaturated compounds containing —CHO groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7922781 | 1979-06-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU190774B true HU190774B (en) | 1986-11-28 |
Family
ID=10506199
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU801601A HU190774B (en) | 1979-06-29 | 1980-06-27 | Process for preparing ether derivatives with pharmacological activity |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4410537A (esLanguage) |
| EP (1) | EP0022229B1 (esLanguage) |
| JP (1) | JPS5649335A (esLanguage) |
| KR (2) | KR850000073B1 (esLanguage) |
| AU (1) | AU545274B2 (esLanguage) |
| DE (1) | DE3061269D1 (esLanguage) |
| DK (1) | DK159770C (esLanguage) |
| FI (1) | FI71929C (esLanguage) |
| GB (1) | GB2053218B (esLanguage) |
| GR (1) | GR68748B (esLanguage) |
| HU (1) | HU190774B (esLanguage) |
| IL (1) | IL60422A (esLanguage) |
| IT (1) | IT1133025B (esLanguage) |
| MW (1) | MW2380A1 (esLanguage) |
| OA (1) | OA06699A (esLanguage) |
| ZA (1) | ZA803880B (esLanguage) |
| ZM (1) | ZM5780A1 (esLanguage) |
| ZW (1) | ZW14480A1 (esLanguage) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR76950B (esLanguage) * | 1980-12-18 | 1984-09-04 | Wellcome Found | |
| GB8606913D0 (en) * | 1986-03-20 | 1986-04-23 | Hider R C | Treatment of sickle cell disease |
| US6083522A (en) | 1997-01-09 | 2000-07-04 | Neucoll, Inc. | Devices for tissue repair and methods for preparation and use thereof |
| RU2300516C2 (ru) * | 1999-11-05 | 2007-06-10 | Эмисфере Текнолоджиз, Инк. | Соединения феноксикарбоновой кислоты и композиции для доставки активных веществ |
| US7279597B1 (en) | 1999-11-05 | 2007-10-09 | Emisphere Technologies, Inc. | Phenyl amine carboxylic acid compounds and compositions for delivering active agents |
| US7129274B1 (en) | 1999-11-05 | 2006-10-31 | Emisphere Technologies Inc. | Phenoxy carboxylic acid compounds and compositions for delivering active agents |
| IL149337A0 (en) * | 1999-11-05 | 2002-11-10 | Emisphere Tech Inc | Phenoxy carboxylic acid compounds and compositions for delivering active agents |
| JP2003528068A (ja) * | 2000-03-17 | 2003-09-24 | コリクサ コーポレイション | 新規両親媒性アルデヒドならびにアジュバントおよび免疫エフェクターとしてのそれらの使用 |
| US8246969B2 (en) | 2001-11-16 | 2012-08-21 | Skinmedica, Inc. | Compositions containing aromatic aldehydes and their use in treatments |
| CA2823647C (en) | 2011-01-07 | 2016-07-19 | Allergan, Inc. | Compositions comprising substituted benzaldehydes and use thereof for lightening skin or treating hyperpigmenation and hypermelanosis disorders |
| PT3141542T (pt) | 2011-12-28 | 2020-06-16 | Global Blood Therapeutics Inc | Compostos de benzaldeído substituído e métodos para a sua utilização no aumento da oxigenação de tecidos |
| EP2797597B1 (en) * | 2011-12-28 | 2020-02-26 | Global Blood Therapeutics, Inc. | Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation |
| US9604999B2 (en) | 2013-03-15 | 2017-03-28 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US9802900B2 (en) | 2013-03-15 | 2017-10-31 | Global Blood Therapeutics, Inc. | Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin |
| US10266551B2 (en) | 2013-03-15 | 2019-04-23 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US9422279B2 (en) | 2013-03-15 | 2016-08-23 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| AU2014237330A1 (en) | 2013-03-15 | 2015-09-17 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US20140274961A1 (en) | 2013-03-15 | 2014-09-18 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| ES2890077T3 (es) | 2013-03-15 | 2022-01-17 | Global Blood Therapeutics Inc | Compuestos y usos de los mismos para la modulación de la hemoglobina |
| AU2014237340C1 (en) * | 2013-03-15 | 2018-11-08 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US8952171B2 (en) | 2013-03-15 | 2015-02-10 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US9458139B2 (en) | 2013-03-15 | 2016-10-04 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US10100043B2 (en) | 2013-03-15 | 2018-10-16 | Global Blood Therapeutics, Inc. | Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation |
| EP3816155A1 (en) * | 2013-08-23 | 2021-05-05 | Virginia Commonwealth University | Ester nitrates derivatives of aromatic aldehydes with multiple pharmalogic properties to treat sickle cell disease |
| EA202092627A1 (ru) | 2013-11-18 | 2021-09-30 | Глобал Блад Терапьютикс, Инк. | Соединения и их применения для модуляции гемоглобина |
| PL3102208T5 (pl) | 2014-02-07 | 2024-10-14 | Global Blood Therapeutics, Inc. | Krystaliczny polimorf wolnej zasady 2-hydroksy-6-((2-(1-izopropylo-1h-pirazol-5-ilo)pirydyn-3-ylo)metoksy)benzaldehydu |
| US10238650B2 (en) | 2015-03-06 | 2019-03-26 | Beyondspring Pharmaceuticals, Inc. | Method of treating cancer associated with a RAS mutation |
| MA41841A (fr) | 2015-03-30 | 2018-02-06 | Global Blood Therapeutics Inc | Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs |
| PL3383392T3 (pl) | 2015-12-04 | 2025-11-17 | Global Blood Therapeutics, Inc. | Schematy dawkowania dla 2-hydroksy-6-((2-(1-izopropylo-1H-pirazol-5-ilo)pirydyn3-ylo)metoksy)benzaldehydu |
| JP2019511565A (ja) * | 2016-02-08 | 2019-04-25 | ビヨンドスプリング ファーマシューティカルズ，インコーポレイテッド | ツカレゾールまたはそのアナログを含む組成物 |
| TWI663160B (zh) | 2016-05-12 | 2019-06-21 | 全球血液治療公司 | 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法 |
| EP3463337A4 (en) | 2016-06-06 | 2020-02-12 | Beyondspring Pharmaceuticals, Inc. | COMPOSITION AND METHOD FOR REDUCING NEUTROPENIA |
| TW202332423A (zh) | 2016-10-12 | 2023-08-16 | 美商全球血液治療公司 | 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑 |
| JP2020503363A (ja) | 2017-01-06 | 2020-01-30 | ビヨンドスプリング ファーマシューティカルズ，インコーポレイテッド | チューブリン結合化合物およびその治療的使用 |
| CN110381938A (zh) | 2017-02-01 | 2019-10-25 | 大连万春布林医药有限公司 | 减少中性粒细胞缺乏症的方法 |
| US11401241B2 (en) * | 2018-03-22 | 2022-08-02 | Virginia Commonwealth University | Aromatic aldehydes with sustained and enhanced in vitro and in vivo pharmacologic activity to treat sickle cell disease |
| ES2966707T3 (es) | 2018-10-01 | 2024-04-23 | Global Blood Therapeutics Inc | Moduladores de la hemoglobina para el tratamiento de la drepanocitosis |
| WO2020106642A1 (en) | 2018-11-19 | 2020-05-28 | Global Blood Therapeutics, Inc. | 2-formyl-3-hydroxyphenyloxymethyl compounds capable of modulating hemoglobin |
| US12479816B2 (en) | 2019-02-08 | 2025-11-25 | University of Pittsburgh—of the Commonwealth System of Higher Education | 20-HETE formation inhibitors |
| CA3215047A1 (en) | 2021-04-09 | 2022-10-13 | Lan Huang | Therapeutic compositions and methods for treating tumors |
| JP2025537075A (ja) * | 2022-11-07 | 2025-11-14 | バージニア コモンウェルス ユニバーシティー | 鎌状赤血球症を治療するための直接的なポリマー不安定化効果を有するベンズアルデヒド化合物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL236575A (esLanguage) * | 1958-04-30 | |||
| CH543472A (fr) * | 1969-01-31 | 1973-10-31 | Orchimed Sa | Procédé pour la préparation d'acides phénoxyalcoyl-carboxyliques |
| DE2209128C3 (de) | 1971-03-05 | 1981-10-22 | CIBA-GEIGY AG, 4002 Basel | Bis-Stilbenverbindungen, Verfahren zu deren Herstellung und deren Verwendung als optische Aufheller |
| CH550776A (de) | 1971-03-05 | 1974-06-28 | Ciba Geigy Ag | Herstellung neuer bis-stilbenverbindungen. |
| GB1511645A (en) | 1974-05-31 | 1978-05-24 | Univ Ife | Sickle cell anaemia treatment |
| US4137309A (en) * | 1976-10-14 | 1979-01-30 | The Procter & Gamble Company | Therapeutic treatment |
-
1980
- 1980-06-27 JP JP8764580A patent/JPS5649335A/ja active Granted
- 1980-06-27 IT IT49108/80A patent/IT1133025B/it active
- 1980-06-27 AU AU59697/80A patent/AU545274B2/en not_active Ceased
- 1980-06-27 ZW ZW144/80A patent/ZW14480A1/xx unknown
- 1980-06-27 DE DE8080103657T patent/DE3061269D1/de not_active Expired
- 1980-06-27 ZM ZM57/80A patent/ZM5780A1/xx unknown
- 1980-06-27 IL IL60422A patent/IL60422A/xx not_active IP Right Cessation
- 1980-06-27 GR GR62311A patent/GR68748B/el unknown
- 1980-06-27 FI FI802052A patent/FI71929C/fi not_active IP Right Cessation
- 1980-06-27 KR KR1019800002541A patent/KR850000073B1/ko not_active Expired
- 1980-06-27 DK DK279780A patent/DK159770C/da not_active IP Right Cessation
- 1980-06-27 HU HU801601A patent/HU190774B/hu not_active IP Right Cessation
- 1980-06-27 ZA ZA00803880A patent/ZA803880B/xx unknown
- 1980-06-27 GB GB8021219A patent/GB2053218B/en not_active Expired
- 1980-06-27 MW MW23/80A patent/MW2380A1/xx unknown
- 1980-06-27 EP EP80103657A patent/EP0022229B1/en not_active Expired
- 1980-08-09 OA OA57193A patent/OA06699A/xx unknown
-
1981
- 1981-06-09 US US06/271,950 patent/US4410537A/en not_active Expired - Lifetime
-
1984
- 1984-03-13 KR KR1019840001263A patent/KR850000072B1/ko not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ZA803880B (en) | 1982-02-24 |
| KR850000073B1 (ko) | 1985-02-18 |
| GR68748B (esLanguage) | 1982-02-16 |
| FI71929B (fi) | 1986-11-28 |
| AU545274B2 (en) | 1985-07-11 |
| DE3061269D1 (en) | 1983-01-13 |
| DK279780A (da) | 1980-12-30 |
| JPS5649335A (en) | 1981-05-02 |
| DK159770C (da) | 1991-04-22 |
| EP0022229A1 (en) | 1981-01-14 |
| ZM5780A1 (en) | 1983-11-21 |
| GB2053218B (en) | 1984-01-25 |
| OA06699A (fr) | 1982-05-31 |
| ZW14480A1 (en) | 1982-03-17 |
| KR830002693A (ko) | 1983-05-30 |
| IT1133025B (it) | 1986-07-09 |
| DK159770B (da) | 1990-12-03 |
| IT8049108A0 (it) | 1980-06-27 |
| AU5969780A (en) | 1981-01-08 |
| IL60422A0 (en) | 1980-09-16 |
| KR850000072B1 (ko) | 1985-02-18 |
| FI802052A7 (fi) | 1980-12-30 |
| KR840004668A (ko) | 1984-10-22 |
| US4410537A (en) | 1983-10-18 |
| FI71929C (fi) | 1987-03-09 |
| GB2053218A (en) | 1981-02-04 |
| JPH0154339B2 (esLanguage) | 1989-11-17 |
| IL60422A (en) | 1984-06-29 |
| MW2380A1 (en) | 1982-03-10 |
| EP0022229B1 (en) | 1982-12-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HU90 | Patent valid on 900628 | ||
| HMM4 | Cancellation of final prot. due to non-payment of fee |