IT8049108A0 - Nuovi eteri per uso farmaceutico eprocedimento per la loro preparazione - Google Patents

Nuovi eteri per uso farmaceutico eprocedimento per la loro preparazione

Info

Publication number
IT8049108A0
IT8049108A0 IT8049108A IT4910880A IT8049108A0 IT 8049108 A0 IT8049108 A0 IT 8049108A0 IT 8049108 A IT8049108 A IT 8049108A IT 4910880 A IT4910880 A IT 4910880A IT 8049108 A0 IT8049108 A0 IT 8049108A0
Authority
IT
Italy
Prior art keywords
procedure
preparation
pharmaceutical use
new ethers
ethers
Prior art date
Application number
IT8049108A
Other languages
English (en)
Other versions
IT1133025B (it
Inventor
Geoffrey Kneen
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IT8049108A0 publication Critical patent/IT8049108A0/it
Application granted granted Critical
Publication of IT1133025B publication Critical patent/IT1133025B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/125Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/30Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing —CHO groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/74Unsaturated compounds containing —CHO groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IT49108/80A 1979-06-29 1980-06-27 Nuovi eteri per uso farmaceutico e procedimento per la loro preparazione IT1133025B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7922781 1979-06-29

Publications (2)

Publication Number Publication Date
IT8049108A0 true IT8049108A0 (it) 1980-06-27
IT1133025B IT1133025B (it) 1986-07-09

Family

ID=10506199

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49108/80A IT1133025B (it) 1979-06-29 1980-06-27 Nuovi eteri per uso farmaceutico e procedimento per la loro preparazione

Country Status (18)

Country Link
US (1) US4410537A (it)
EP (1) EP0022229B1 (it)
JP (1) JPS5649335A (it)
KR (2) KR850000073B1 (it)
AU (1) AU545274B2 (it)
DE (1) DE3061269D1 (it)
DK (1) DK159770C (it)
FI (1) FI71929C (it)
GB (1) GB2053218B (it)
GR (1) GR68748B (it)
HU (1) HU190774B (it)
IL (1) IL60422A (it)
IT (1) IT1133025B (it)
MW (1) MW2380A1 (it)
OA (1) OA06699A (it)
ZA (1) ZA803880B (it)
ZM (1) ZM5780A1 (it)
ZW (1) ZW14480A1 (it)

Families Citing this family (39)

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GB2090830B (en) * 1980-12-18 1984-09-26 Wellcome Found Formyl ether derivatives
GB8606913D0 (en) * 1986-03-20 1986-04-23 Hider R C Treatment of sickle cell disease
WO1998030141A2 (en) 1997-01-09 1998-07-16 Cohesion Technologies, Inc. Devices for tissue repair and methods for preparation and use thereof
US7279597B1 (en) 1999-11-05 2007-10-09 Emisphere Technologies, Inc. Phenyl amine carboxylic acid compounds and compositions for delivering active agents
US7129274B1 (en) 1999-11-05 2006-10-31 Emisphere Technologies Inc. Phenoxy carboxylic acid compounds and compositions for delivering active agents
RU2300516C2 (ru) * 1999-11-05 2007-06-10 Эмисфере Текнолоджиз, Инк. Соединения феноксикарбоновой кислоты и композиции для доставки активных веществ
JP5117658B2 (ja) * 1999-11-05 2013-01-16 エミスフェアー・テクノロジーズ・インク フェノキシカルボン酸化合物及び活性剤を送達するための組成物
AU2001245823A1 (en) * 2000-03-17 2001-10-03 Corixa Corporation Novel amphipathic aldehydes and their use as adjuvants and immunoeffectors
US8246969B2 (en) 2001-11-16 2012-08-21 Skinmedica, Inc. Compositions containing aromatic aldehydes and their use in treatments
JP6378878B2 (ja) 2011-01-07 2018-08-22 アラーガン、インコーポレイテッドAllergan,Incorporated メラニン改変組成物および使用方法
US9018210B2 (en) * 2011-12-28 2015-04-28 Global Blood Therapeutics, Inc. Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation
WO2013102145A1 (en) 2011-12-28 2013-07-04 Global Blood Therapeutics, Inc. Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
KR102280614B1 (ko) 2013-03-15 2021-07-21 글로벌 블러드 테라퓨틱스, 인크. 헤모글로빈 조정을 위한 화합물 및 이의 용도
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
WO2014150258A1 (en) 2013-03-15 2014-09-25 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
CN111454200A (zh) 2013-03-15 2020-07-28 全球血液疗法股份有限公司 化合物及其用于调节血红蛋白的用途
WO2014145040A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10800751B2 (en) * 2013-08-23 2020-10-13 Virginia Commonwealth University Ester nitrates derivatives of aromatic aldehydes with multiple pharmalogic properties to treat sickle cell disease
EA202092627A1 (ru) 2013-11-18 2021-09-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
WO2015120133A1 (en) 2014-02-07 2015-08-13 Global Blood Therapeutics, Inc. Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
CA2978567A1 (en) 2015-03-06 2016-09-15 Beyondspring Pharmaceuticals, Inc. Method of treating cancer associated with a ras mutation using plinabulin
MA41841A (fr) 2015-03-30 2018-02-06 Global Blood Therapeutics Inc Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
FI3383392T3 (fi) 2015-12-04 2025-09-11 Global Blood Therapeutics Inc Annosteluohjelmat 2-hydroksi-6-((2-(1-isopropyyli-1h-pyratsol-5-yyli)pyridin-3-yyli)metoksi)bentsaldehydille
BR112018016054A2 (pt) * 2016-02-08 2019-02-12 Beyondspring Pharmaceuticals, Inc. composições farmacêuticas e/ou métodos para tratar câncer e/ou para romper vasculatura de tumor associada ao câncer em indivíduo
TWI752307B (zh) 2016-05-12 2022-01-11 美商全球血液治療公司 新穎化合物及製造化合物之方法
EP3463337A4 (en) 2016-06-06 2020-02-12 Beyondspring Pharmaceuticals, Inc. COMPOSITION AND METHOD FOR REDUCING NEUTROPENIA
TW202332423A (zh) 2016-10-12 2023-08-16 美商全球血液治療公司 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
EP3565812B1 (en) 2017-01-06 2023-12-27 Beyondspring Pharmaceuticals, Inc. Tubulin binding compounds and therapeutic use thereof
EP3576733A4 (en) 2017-02-01 2020-11-25 Beyondspring Pharmaceuticals, Inc. NEUTROPENIA REDUCTION METHOD
WO2019182938A1 (en) * 2018-03-22 2019-09-26 Virginia Commonwealth University Aromatic aldehydes with sustained and enhanced in vitro and in vivo pharmacologic activity to treat sickle cell disease
ES2966707T3 (es) 2018-10-01 2024-04-23 Global Blood Therapeutics Inc Moduladores de la hemoglobina para el tratamiento de la drepanocitosis
CR20210335A (es) 2018-11-19 2021-09-14 Global Blood Therapeutics Inc Compuestos de 2-formil-3-hidroxifeniloximetilo capaces de modular la hemoglobina
WO2022216908A1 (en) 2021-04-09 2022-10-13 Beyondspring Pharmaceuticals, Inc. Therapeutic compositions and methods for treating tumors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU36436A1 (it) * 1958-04-30
CH543472A (fr) * 1969-01-31 1973-10-31 Orchimed Sa Procédé pour la préparation d'acides phénoxyalcoyl-carboxyliques
CH550776A (de) 1971-03-05 1974-06-28 Ciba Geigy Ag Herstellung neuer bis-stilbenverbindungen.
DE2209128C3 (de) 1971-03-05 1981-10-22 CIBA-GEIGY AG, 4002 Basel Bis-Stilbenverbindungen, Verfahren zu deren Herstellung und deren Verwendung als optische Aufheller
GB1511645A (en) 1974-05-31 1978-05-24 Univ Ife Sickle cell anaemia treatment
US4137309A (en) * 1976-10-14 1979-01-30 The Procter & Gamble Company Therapeutic treatment

Also Published As

Publication number Publication date
FI802052A7 (fi) 1980-12-30
AU545274B2 (en) 1985-07-11
FI71929C (fi) 1987-03-09
KR830002693A (ko) 1983-05-30
IL60422A0 (en) 1980-09-16
US4410537A (en) 1983-10-18
HU190774B (en) 1986-11-28
FI71929B (fi) 1986-11-28
OA06699A (fr) 1982-05-31
DK159770C (da) 1991-04-22
DE3061269D1 (en) 1983-01-13
GB2053218A (en) 1981-02-04
KR850000073B1 (ko) 1985-02-18
KR840004668A (ko) 1984-10-22
IL60422A (en) 1984-06-29
JPH0154339B2 (it) 1989-11-17
GR68748B (it) 1982-02-16
EP0022229A1 (en) 1981-01-14
JPS5649335A (en) 1981-05-02
KR850000072B1 (ko) 1985-02-18
GB2053218B (en) 1984-01-25
MW2380A1 (en) 1982-03-10
DK159770B (da) 1990-12-03
IT1133025B (it) 1986-07-09
AU5969780A (en) 1981-01-08
EP0022229B1 (en) 1982-12-08
ZW14480A1 (en) 1982-03-17
ZM5780A1 (en) 1983-11-21
ZA803880B (en) 1982-02-24
DK279780A (da) 1980-12-30

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940629