IT8049108A0 - Nuovi eteri per uso farmaceutico eprocedimento per la loro preparazione - Google Patents

Nuovi eteri per uso farmaceutico eprocedimento per la loro preparazione

Info

Publication number
IT8049108A0
IT8049108A0 IT8049108A IT4910880A IT8049108A0 IT 8049108 A0 IT8049108 A0 IT 8049108A0 IT 8049108 A IT8049108 A IT 8049108A IT 4910880 A IT4910880 A IT 4910880A IT 8049108 A0 IT8049108 A0 IT 8049108A0
Authority
IT
Italy
Prior art keywords
procedure
preparation
pharmaceutical use
new ethers
ethers
Prior art date
Application number
IT8049108A
Other languages
English (en)
Other versions
IT1133025B (it
Inventor
Geoffrey Kneen
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IT8049108A0 publication Critical patent/IT8049108A0/it
Application granted granted Critical
Publication of IT1133025B publication Critical patent/IT1133025B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/125Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/30Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing —CHO groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/74Unsaturated compounds containing —CHO groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IT49108/80A 1979-06-29 1980-06-27 Nuovi eteri per uso farmaceutico e procedimento per la loro preparazione IT1133025B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7922781 1979-06-29

Publications (2)

Publication Number Publication Date
IT8049108A0 true IT8049108A0 (it) 1980-06-27
IT1133025B IT1133025B (it) 1986-07-09

Family

ID=10506199

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49108/80A IT1133025B (it) 1979-06-29 1980-06-27 Nuovi eteri per uso farmaceutico e procedimento per la loro preparazione

Country Status (18)

Country Link
US (1) US4410537A (it)
EP (1) EP0022229B1 (it)
JP (1) JPS5649335A (it)
KR (2) KR850000073B1 (it)
AU (1) AU545274B2 (it)
DE (1) DE3061269D1 (it)
DK (1) DK159770C (it)
FI (1) FI71929C (it)
GB (1) GB2053218B (it)
GR (1) GR68748B (it)
HU (1) HU190774B (it)
IL (1) IL60422A (it)
IT (1) IT1133025B (it)
MW (1) MW2380A1 (it)
OA (1) OA06699A (it)
ZA (1) ZA803880B (it)
ZM (1) ZM5780A1 (it)
ZW (1) ZW14480A1 (it)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL64573A (en) * 1980-12-18 1985-04-30 Wellcome Found Derivatives of formylphenoxyalkanoic acids and formylphenoxymethylbenzoic acids,their preparation and pharmaceutical formulations containing them
GB8606913D0 (en) * 1986-03-20 1986-04-23 Hider R C Treatment of sickle cell disease
WO1998030252A1 (en) 1997-01-09 1998-07-16 Cohesion Technologies, Inc. Methods and apparatuses for making swellable uniformly shaped devices from polymeric materials
RU2300516C2 (ru) * 1999-11-05 2007-06-10 Эмисфере Текнолоджиз, Инк. Соединения феноксикарбоновой кислоты и композиции для доставки активных веществ
IL149337A0 (en) * 1999-11-05 2002-11-10 Emisphere Tech Inc Phenoxy carboxylic acid compounds and compositions for delivering active agents
US7129274B1 (en) 1999-11-05 2006-10-31 Emisphere Technologies Inc. Phenoxy carboxylic acid compounds and compositions for delivering active agents
US7279597B1 (en) 1999-11-05 2007-10-09 Emisphere Technologies, Inc. Phenyl amine carboxylic acid compounds and compositions for delivering active agents
US6649172B2 (en) 2000-03-17 2003-11-18 Corixa Corporation Amphipathic aldehydes and their uses as adjuvants and immunoeffectors
US8246969B2 (en) 2001-11-16 2012-08-21 Skinmedica, Inc. Compositions containing aromatic aldehydes and their use in treatments
CA2823647C (en) 2011-01-07 2016-07-19 Allergan, Inc. Compositions comprising substituted benzaldehydes and use thereof for lightening skin or treating hyperpigmenation and hypermelanosis disorders
EP2797597B1 (en) * 2011-12-28 2020-02-26 Global Blood Therapeutics, Inc. Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
SG10201702513SA (en) * 2011-12-28 2017-05-30 Univ California Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
PE20160078A1 (es) 2013-03-15 2016-03-02 Global Blood Therapeutics Inc Compuestos y sus usos para modular la hemoglobina
US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
WO2014145040A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
US20160083343A1 (en) 2013-03-15 2016-03-24 Global Blood Therapeutics, Inc Compounds and uses thereof for the modulation of hemoglobin
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
ES2890077T3 (es) 2013-03-15 2022-01-17 Global Blood Therapeutics Inc Compuestos y usos de los mismos para la modulación de la hemoglobina
US10800751B2 (en) * 2013-08-23 2020-10-13 Virginia Commonwealth University Ester nitrates derivatives of aromatic aldehydes with multiple pharmalogic properties to treat sickle cell disease
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
MX361810B (es) 2014-02-07 2018-12-14 Global Blood Therapeutics Inc Polimorfos cristalinos de la base libre de 2-hidroxi-6-((2-(1-isop ropil-1h-pirazol-5-il-)piridin-3-il)metoxi)benzaldehido.
SG11201707127VA (en) 2015-03-06 2017-09-28 Beyondspring Pharmaceuticals Inc Method of treating cancer associated with a ras mutation
MA41841A (fr) 2015-03-30 2018-02-06 Global Blood Therapeutics Inc Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
MA43373A (fr) 2015-12-04 2018-10-10 Global Blood Therapeutics Inc Régimes posologiques pour 2-hydroxy-6-((2- (1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)méthoxy)benzaldéhyde
CA3013467A1 (en) * 2016-02-08 2017-08-17 Beyondspring Pharmaceuticals, Inc. Compositions containing tucaresol or its analogs
TWI825524B (zh) 2016-05-12 2023-12-11 美商全球血液治療公司 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法
RU2760348C2 (ru) 2016-06-06 2021-11-24 Бейондспринг Фармасьютикалс, Инк. Способ уменьшения нейтропении
TWI778983B (zh) 2016-10-12 2022-10-01 美商全球血液治療公司 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
WO2018129381A1 (en) 2017-01-06 2018-07-12 Beyondspring Pharmaceuticals, Inc. Tubulin binding compounds and therapeutic use thereof
BR112019015974A2 (pt) 2017-02-01 2020-03-31 Beyondspring Pharmaceuticals, Inc. Método para reduzir neutropenia
WO2019182938A1 (en) * 2018-03-22 2019-09-26 Virginia Commonwealth University Aromatic aldehydes with sustained and enhanced in vitro and in vivo pharmacologic activity to treat sickle cell disease
US11014884B2 (en) 2018-10-01 2021-05-25 Global Blood Therapeutics, Inc. Modulators of hemoglobin
MD3880654T2 (ro) 2018-11-19 2022-05-31 Global Blood Therapeutics Inc Compuși 2-formil-3-hidroxifeniloximetilici capabili de modularea hemoglobinei
WO2020163689A1 (en) 2019-02-08 2020-08-13 University Of Pittsburgh - Of The Commonwealth System Of Higher Education 20-hete formation inhibitors
WO2022216908A1 (en) 2021-04-09 2022-10-13 Beyondspring Pharmaceuticals, Inc. Therapeutic compositions and methods for treating tumors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU36787A1 (it) * 1958-04-30
CH543472A (fr) * 1969-01-31 1973-10-31 Orchimed Sa Procédé pour la préparation d'acides phénoxyalcoyl-carboxyliques
CH550776A (de) 1971-03-05 1974-06-28 Ciba Geigy Ag Herstellung neuer bis-stilbenverbindungen.
DE2209128C3 (de) 1971-03-05 1981-10-22 CIBA-GEIGY AG, 4002 Basel Bis-Stilbenverbindungen, Verfahren zu deren Herstellung und deren Verwendung als optische Aufheller
GB1511645A (en) * 1974-05-31 1978-05-24 Univ Ife Sickle cell anaemia treatment
US4137309A (en) * 1976-10-14 1979-01-30 The Procter & Gamble Company Therapeutic treatment

Also Published As

Publication number Publication date
ZA803880B (en) 1982-02-24
KR850000072B1 (ko) 1985-02-18
FI71929B (fi) 1986-11-28
JPH0154339B2 (it) 1989-11-17
JPS5649335A (en) 1981-05-02
HU190774B (en) 1986-11-28
GR68748B (it) 1982-02-16
IL60422A (en) 1984-06-29
AU545274B2 (en) 1985-07-11
EP0022229B1 (en) 1982-12-08
EP0022229A1 (en) 1981-01-14
ZM5780A1 (en) 1983-11-21
IT1133025B (it) 1986-07-09
US4410537A (en) 1983-10-18
OA06699A (fr) 1982-05-31
FI71929C (fi) 1987-03-09
DK279780A (da) 1980-12-30
DK159770C (da) 1991-04-22
GB2053218A (en) 1981-02-04
KR830002693A (ko) 1983-05-30
IL60422A0 (en) 1980-09-16
ZW14480A1 (en) 1982-03-17
MW2380A1 (en) 1982-03-10
FI802052A7 (fi) 1980-12-30
KR840004668A (ko) 1984-10-22
DK159770B (da) 1990-12-03
KR850000073B1 (ko) 1985-02-18
AU5969780A (en) 1981-01-08
DE3061269D1 (en) 1983-01-13
GB2053218B (en) 1984-01-25

Similar Documents

Publication Publication Date Title
IT8049108A0 (it) Nuovi eteri per uso farmaceutico eprocedimento per la loro preparazione
IT1106143B (it) Peptidi e loro derivati per uso farmaceutico e procedimento per la preparazione delle formulazioni che li contengono
IT1143047B (it) Composti diazepinici per uso farmaceutico e loro procedimento di preparazione
IT1188970B (it) Derivati della moranolina e procedimento per la loro preparazione
IT1129933B (it) Derivati tioetilammidici loro composizioni farmaceutiche e procedimento per la loro preparazione
DE3062268D1 (en) Alkoxybenzylpyridopyrimidines, methods for their preparation and pharmaceutical formulations thereof
IT8148166A0 (it) Ne e loro uso terapeutico esteri di mercaptoacil-carnitine procedimento per la loro preparazio
IT1147741B (it) Derivati di idrossiammino eburnano e procedimento per la loro preparazione
IT1132403B (it) Derivati di alovincamone e procedimento per la loro preparazione
AR229875A1 (es) Procedimiento para la preparacion de derivados de 4-sulfanoil fenil-3-sustituido-2-fenilimino-4-tiazolina,intermediarios para su uso exclusivo en el procedimiento y procedimiento para obtener preparados farmaceuticos
IT1171361B (it) Amminociclopentanon-ammidi e procedimento per la loro preparazione e formulazione farmaceutica
IT1201523B (it) Eterociclilfenilfomramidine,processi per la loro preparazione e loro uso farmaceutico
IT1132404B (it) Derivati di 10-alo-e-omoeburnano e procedimento per la loro preparazione
IT1170862B (it) Mercaptoacil-carnitine procedimento per la loro preparazione e loro uso terapeutico
IT1169459B (it) 1-piridilossi-3-indolilalchilammino-2-propanoli sostituiti,procedimento di preparazione e loro uso
IT8048512A0 (it) Composizioni antibatteriche a basedi cloresidina per uso dermatologico e procedimento per la loro preparazione
IT1130074B (it) Composti policiclici e procedimento per la loro preparazione
IT1212412B (it) Derivati della benzo-as-triazina e procedimento per la loro preparazione.
IT1163698B (it) Derivati di 1-ftalazone, procedimento per la loro preparazione, e loro impiego
IT1143906B (it) Tiocarnitine procedimento per la loro preparazione e loro uso terapeutico
IT1169903B (it) Derivati epossicarbaciclinici, loro preparazione e loro uso
IT8067851A0 (it) Derivati di cefalosporina sommini strabili per via orale e procedimento per la loro preparazione
IT8024015A0 (it) Derivati del15-idrossi-e-omoeburnano alogenati e procedimento per la loro preparazione.
IT8222637A0 (it) Eterociclilfenilsolfonil e fosfonilamidine sostituite, procedimento per la loro preparazione e loro uso farmaceutico.
IT1115788B (it) 5-fenil-2-ossazolo carbossimmidammi di per uso farmaceutico

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940629