HU187393B - Process for producing phenyl-substitited pyrido-bracket-1,4-bracket closed-benzodiazepines and intermediates and pharmaceutical compositions containing thes as active agents - Google Patents

Process for producing phenyl-substitited pyrido-bracket-1,4-bracket closed-benzodiazepines and intermediates and pharmaceutical compositions containing thes as active agents Download PDF

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Publication number
HU187393B
HU187393B HU813777A HU377781A HU187393B HU 187393 B HU187393 B HU 187393B HU 813777 A HU813777 A HU 813777A HU 377781 A HU377781 A HU 377781A HU 187393 B HU187393 B HU 187393B
Authority
HU
Hungary
Prior art keywords
formula
pyrido
compound
alkyl
product
Prior art date
Application number
HU813777A
Other languages
English (en)
Hungarian (hu)
Inventor
Jr Chandler Roy Taylor
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of HU187393B publication Critical patent/HU187393B/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU813777A 1981-09-24 1981-12-15 Process for producing phenyl-substitited pyrido-bracket-1,4-bracket closed-benzodiazepines and intermediates and pharmaceutical compositions containing thes as active agents HU187393B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30508081A 1981-09-24 1981-09-24

Publications (1)

Publication Number Publication Date
HU187393B true HU187393B (en) 1985-12-28

Family

ID=23179241

Family Applications (2)

Application Number Title Priority Date Filing Date
HU813777A HU187393B (en) 1981-09-24 1981-12-15 Process for producing phenyl-substitited pyrido-bracket-1,4-bracket closed-benzodiazepines and intermediates and pharmaceutical compositions containing thes as active agents
HU843212A HU189426B (en) 1981-09-24 1981-12-15 Process for producing /2-/amino-piridil/-amino-fenil/-aril-methanon derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU843212A HU189426B (en) 1981-09-24 1981-12-15 Process for producing /2-/amino-piridil/-amino-fenil/-aril-methanon derivatives

Country Status (27)

Country Link
JP (1) JPS5865290A (es)
KR (1) KR890000764B1 (es)
BE (1) BE891666A (es)
CA (1) CA1199324A (es)
CH (1) CH651833A5 (es)
DE (1) DE3150522A1 (es)
DK (3) DK186282A (es)
EG (1) EG15904A (es)
ES (6) ES8303348A1 (es)
FI (1) FI71935C (es)
FR (1) FR2515183B1 (es)
GR (1) GR78473B (es)
HU (2) HU187393B (es)
IE (1) IE52493B1 (es)
IL (1) IL64284A (es)
IN (1) IN156080B (es)
IT (1) IT1146728B (es)
LU (1) LU83865A1 (es)
NL (1) NL8200549A (es)
NO (1) NO157700C (es)
NZ (1) NZ198999A (es)
PH (2) PH17847A (es)
PL (6) PL139381B1 (es)
PT (1) PT74286B (es)
SE (2) SE448629B (es)
YU (1) YU46128B (es)
ZA (1) ZA817866B (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3825549A (en) * 1972-10-24 1974-07-23 Squibb & Sons Inc Certain dihydropyrido(2,1-b)(1,3)benzodi-azepines and benzodiazocines
DE2424811C3 (de) * 1974-05-22 1981-08-20 Dr. Karl Thomae Gmbh, 7950 Biberach Pyrido-benzodiazepinone, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
SE422799B (sv) * 1975-05-28 1982-03-29 Merck & Co Inc Analogiforfarande for framstellning av 1,3-dihydroimidazo (4,5-b)pyridin-2-oner

Also Published As

Publication number Publication date
NL8200549A (nl) 1983-04-18
PL137068B1 (en) 1986-04-30
SE455305B (sv) 1988-07-04
ES8604531A1 (es) 1986-02-01
ZA817866B (en) 1982-10-27
ES507971A0 (es) 1983-02-01
LU83865A1 (fr) 1983-09-02
FR2515183A1 (fr) 1983-04-29
ES516051A0 (es) 1983-09-16
KR830009058A (ko) 1983-12-17
PL241409A1 (en) 1984-05-21
FI71935B (fi) 1986-11-28
EG15904A (en) 1987-03-30
PL234426A1 (en) 1984-01-02
ES8607726A1 (es) 1986-06-01
PH20536A (en) 1987-02-09
NO813839L (no) 1983-03-25
DK403387A (da) 1987-08-03
ES516052A0 (es) 1984-01-16
NO157700B (no) 1988-01-25
NZ198999A (en) 1987-07-31
SE8106573L (sv) 1983-03-25
FI813976L (fi) 1983-03-25
PL138859B1 (en) 1986-11-29
JPS5865290A (ja) 1983-04-18
DK403487D0 (da) 1987-08-03
CH651833A5 (fr) 1985-10-15
ES8308563A1 (es) 1983-09-16
YU46128B (sh) 1993-05-28
FR2515183B1 (fr) 1986-11-14
ES526563A0 (es) 1986-02-01
PT74286A (en) 1982-02-01
GR78473B (es) 1984-09-27
IE812769L (en) 1983-03-24
IT8168605A0 (it) 1981-12-09
BE891666A (fr) 1982-04-16
DE3150522A1 (de) 1983-04-07
DK403487A (da) 1987-08-03
ES8402295A1 (es) 1984-01-16
IL64284A0 (en) 1982-02-28
IL64284A (en) 1986-12-31
PL143322B1 (en) 1988-02-29
SE8600688D0 (sv) 1986-02-17
FI71935C (fi) 1987-03-09
PL143596B1 (en) 1988-02-29
PL143597B1 (en) 1988-02-29
IE52493B1 (en) 1987-11-25
CA1199324A (en) 1986-01-14
PT74286B (en) 1983-06-27
KR890000764B1 (ko) 1989-04-05
SE448629B (sv) 1987-03-09
IN156080B (es) 1985-05-11
HUT34732A (en) 1985-04-28
ES8504148A1 (es) 1985-04-01
ES543328A0 (es) 1986-06-01
DK186282A (da) 1983-03-25
ES526562A0 (es) 1985-04-01
ES8303348A1 (es) 1983-02-01
SE8600688L (sv) 1986-02-17
YU62582A (en) 1986-04-30
PH17847A (en) 1985-01-09
IT1146728B (it) 1986-11-19
PL241410A1 (en) 1984-01-02
PL139381B1 (en) 1987-01-31
NO157700C (no) 1988-05-04
DK403387D0 (da) 1987-08-03
HU189426B (en) 1986-07-28

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee