FR2515183B1 - Pyrido(1,4)benzodiazepines phenyl-substituees et leurs intermediaires, utiles comme medicaments antidepresseurs - Google Patents

Pyrido(1,4)benzodiazepines phenyl-substituees et leurs intermediaires, utiles comme medicaments antidepresseurs

Info

Publication number
FR2515183B1
FR2515183B1 FR8124111A FR8124111A FR2515183B1 FR 2515183 B1 FR2515183 B1 FR 2515183B1 FR 8124111 A FR8124111 A FR 8124111A FR 8124111 A FR8124111 A FR 8124111A FR 2515183 B1 FR2515183 B1 FR 2515183B1
Authority
FR
France
Prior art keywords
benzodiazepines
pyrido
intermediates
phenyl
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8124111A
Other languages
English (en)
Other versions
FR2515183A1 (fr
Inventor
Chandler Roy Taylor Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AH Robins Co Inc
Original Assignee
AH Robins Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AH Robins Co Inc filed Critical AH Robins Co Inc
Publication of FR2515183A1 publication Critical patent/FR2515183A1/fr
Application granted granted Critical
Publication of FR2515183B1 publication Critical patent/FR2515183B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR8124111A 1981-09-24 1981-12-23 Pyrido(1,4)benzodiazepines phenyl-substituees et leurs intermediaires, utiles comme medicaments antidepresseurs Expired FR2515183B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30508081A 1981-09-24 1981-09-24

Publications (2)

Publication Number Publication Date
FR2515183A1 FR2515183A1 (fr) 1983-04-29
FR2515183B1 true FR2515183B1 (fr) 1986-11-14

Family

ID=23179241

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8124111A Expired FR2515183B1 (fr) 1981-09-24 1981-12-23 Pyrido(1,4)benzodiazepines phenyl-substituees et leurs intermediaires, utiles comme medicaments antidepresseurs

Country Status (27)

Country Link
JP (1) JPS5865290A (fr)
KR (1) KR890000764B1 (fr)
BE (1) BE891666A (fr)
CA (1) CA1199324A (fr)
CH (1) CH651833A5 (fr)
DE (1) DE3150522A1 (fr)
DK (3) DK186282A (fr)
EG (1) EG15904A (fr)
ES (6) ES8303348A1 (fr)
FI (1) FI71935C (fr)
FR (1) FR2515183B1 (fr)
GR (1) GR78473B (fr)
HU (2) HU189426B (fr)
IE (1) IE52493B1 (fr)
IL (1) IL64284A (fr)
IN (1) IN156080B (fr)
IT (1) IT1146728B (fr)
LU (1) LU83865A1 (fr)
NL (1) NL8200549A (fr)
NO (1) NO157700C (fr)
NZ (1) NZ198999A (fr)
PH (2) PH17847A (fr)
PL (6) PL143596B1 (fr)
PT (1) PT74286B (fr)
SE (2) SE448629B (fr)
YU (1) YU46128B (fr)
ZA (1) ZA817866B (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3825549A (en) * 1972-10-24 1974-07-23 Squibb & Sons Inc Certain dihydropyrido(2,1-b)(1,3)benzodi-azepines and benzodiazocines
DE2424811C3 (de) * 1974-05-22 1981-08-20 Dr. Karl Thomae Gmbh, 7950 Biberach Pyrido-benzodiazepinone, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
SE422799B (sv) * 1975-05-28 1982-03-29 Merck & Co Inc Analogiforfarande for framstellning av 1,3-dihydroimidazo (4,5-b)pyridin-2-oner

Also Published As

Publication number Publication date
KR890000764B1 (ko) 1989-04-05
ES8308563A1 (es) 1983-09-16
DK403487D0 (da) 1987-08-03
PL234426A1 (en) 1984-01-02
DK403387D0 (da) 1987-08-03
GR78473B (fr) 1984-09-27
BE891666A (fr) 1982-04-16
PL241409A1 (en) 1984-05-21
PL139381B1 (en) 1987-01-31
FR2515183A1 (fr) 1983-04-29
IL64284A0 (en) 1982-02-28
IT8168605A0 (it) 1981-12-09
HUT34732A (en) 1985-04-28
FI71935C (fi) 1987-03-09
HU187393B (en) 1985-12-28
IE52493B1 (en) 1987-11-25
NO157700C (no) 1988-05-04
ZA817866B (en) 1982-10-27
SE8600688D0 (sv) 1986-02-17
NO157700B (no) 1988-01-25
ES516051A0 (es) 1983-09-16
YU62582A (en) 1986-04-30
SE8600688L (sv) 1986-02-17
PL143597B1 (en) 1988-02-29
PL143322B1 (en) 1988-02-29
PT74286A (en) 1982-02-01
ES507971A0 (es) 1983-02-01
ES8607726A1 (es) 1986-06-01
HU189426B (en) 1986-07-28
PL241410A1 (en) 1984-01-02
PL138859B1 (en) 1986-11-29
IE812769L (en) 1983-03-24
SE455305B (sv) 1988-07-04
SE448629B (sv) 1987-03-09
EG15904A (en) 1987-03-30
PL143596B1 (en) 1988-02-29
ES543328A0 (es) 1986-06-01
YU46128B (sh) 1993-05-28
ES526563A0 (es) 1986-02-01
IT1146728B (it) 1986-11-19
ES8504148A1 (es) 1985-04-01
SE8106573L (sv) 1983-03-25
CH651833A5 (fr) 1985-10-15
PH17847A (en) 1985-01-09
LU83865A1 (fr) 1983-09-02
NZ198999A (en) 1987-07-31
FI813976L (fi) 1983-03-25
DK403487A (da) 1987-08-03
PH20536A (en) 1987-02-09
JPS5865290A (ja) 1983-04-18
IL64284A (en) 1986-12-31
CA1199324A (fr) 1986-01-14
NO813839L (no) 1983-03-25
DK403387A (da) 1987-08-03
DE3150522A1 (de) 1983-04-07
PT74286B (en) 1983-06-27
DK186282A (da) 1983-03-25
PL137068B1 (en) 1986-04-30
FI71935B (fi) 1986-11-28
ES8303348A1 (es) 1983-02-01
ES8604531A1 (es) 1986-02-01
ES516052A0 (es) 1984-01-16
ES526562A0 (es) 1985-04-01
ES8402295A1 (es) 1984-01-16
KR830009058A (ko) 1983-12-17
IN156080B (fr) 1985-05-11
NL8200549A (nl) 1983-04-18

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Legal Events

Date Code Title Description
ST Notification of lapse