HU180273B - Process for producing 1,5-disubstituted-2-pyrrolidone derivatives - Google Patents

Process for producing 1,5-disubstituted-2-pyrrolidone derivatives Download PDF

Info

Publication number
HU180273B
HU180273B HU77PI587A HUPI000587A HU180273B HU 180273 B HU180273 B HU 180273B HU 77PI587 A HU77PI587 A HU 77PI587A HU PI000587 A HUPI000587 A HU PI000587A HU 180273 B HU180273 B HU 180273B
Authority
HU
Hungary
Prior art keywords
pyrrolidone
group
formula
reaction
prepared
Prior art date
Application number
HU77PI587A
Other languages
German (de)
English (en)
Hungarian (hu)
Inventor
Albin J Nelson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of HU180273B publication Critical patent/HU180273B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU77PI587A 1976-08-06 1977-08-05 Process for producing 1,5-disubstituted-2-pyrrolidone derivatives HU180273B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71236276A 1976-08-06 1976-08-06

Publications (1)

Publication Number Publication Date
HU180273B true HU180273B (en) 1983-02-28

Family

ID=24861795

Family Applications (1)

Application Number Title Priority Date Filing Date
HU77PI587A HU180273B (en) 1976-08-06 1977-08-05 Process for producing 1,5-disubstituted-2-pyrrolidone derivatives

Country Status (31)

Country Link
JP (2) JPS5321159A (sv)
AR (1) AR217080A1 (sv)
AT (1) AT362887B (sv)
AU (1) AU508007B2 (sv)
BE (1) BE857506A (sv)
BG (1) BG31073A3 (sv)
CA (1) CA1077948A (sv)
CH (1) CH624934A5 (sv)
CS (1) CS221269B2 (sv)
DD (2) DD143768A5 (sv)
DE (1) DE2735904A1 (sv)
DK (1) DK352077A (sv)
ES (2) ES461388A1 (sv)
FI (1) FI70009C (sv)
FR (1) FR2369260A1 (sv)
GB (2) GB1556569A (sv)
GR (1) GR68688B (sv)
HU (1) HU180273B (sv)
IE (1) IE45505B1 (sv)
IL (1) IL52615A (sv)
LU (1) LU77936A1 (sv)
NL (1) NL7708637A (sv)
NO (1) NO772752L (sv)
NZ (1) NZ184806A (sv)
PH (1) PH17398A (sv)
PL (2) PL200124A1 (sv)
PT (1) PT66891B (sv)
SE (1) SE423813B (sv)
SU (3) SU703016A3 (sv)
YU (1) YU192577A (sv)
ZA (1) ZA774704B (sv)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5695569A (en) * 1979-12-27 1981-08-03 Canon Inc Forming method for bar lens sphere face
US4321201A (en) * 1980-09-22 1982-03-23 E. I. Du Pont De Nemours And Company Optically active tert-alkyl 7-(2-oxo-5-carbonyloxypyrrolidinyl) heptanoates
JPS59137224A (ja) * 1983-01-25 1984-08-07 Mitsubishi Electric Corp 電気鉄道用き電電圧補償装置
ATE327751T1 (de) * 2000-01-31 2006-06-15 Pfizer Prod Inc Verwendung von aktivatoren des prostaglandinrezeptores 4 zur behandlung von akuter oder chronischer niereninsuffizienz
WO2002024647A1 (fr) * 2000-09-21 2002-03-28 Ono Pharmaceutical Co., Ltd. Agonistes du recepteur de l'ep4 comprenant comme principe actif des derives de la 8-azaprostaglandine
DE60130675T2 (de) * 2000-11-27 2008-01-24 Pfizer Products Inc., Groton Selektive agonisten des ep4 rezeptors für die behandlung von osteoporose
KR100826866B1 (ko) * 2001-07-23 2008-05-06 오노 야꾸힝 고교 가부시키가이샤 Ep4 아고니스트를 유효 성분으로 하는 골량 저하질환의 치료제
AU2003207900A1 (en) * 2002-03-18 2003-09-29 Pfizer Products Inc. Methods of treatment with selective ep4 receptor agonists
US6573294B1 (en) * 2002-05-14 2003-06-03 Allergan, Inc. 8-azaprostaglandin analogs as agents for lowering intraocular pressure
EP1586564B1 (en) * 2003-01-21 2012-11-28 Ono Pharmaceutical Co., Ltd. 8-azaprostaglandin derivatives and medicinal uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386146A (en) * 1972-05-03 1975-03-05 Ici Ltd Cyclopentane derivatives
JPS511460A (en) * 1974-06-24 1976-01-08 Tanabe Seiyaku Co 22 piroridonjudotaino seiho
JPS514166A (ja) * 1974-06-28 1976-01-14 Tanabe Seiyaku Co 22piroridonjudotaino seiho
US3975399A (en) * 1974-08-06 1976-08-17 E. I. Du Pont De Nemours And Company 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones
DE2528664A1 (de) * 1975-06-27 1977-01-13 Hoechst Ag Pyrrolidone und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
PH17398A (en) 1984-08-08
JPS5555161A (en) 1980-04-22
BG31073A3 (en) 1981-10-15
ATA579477A (de) 1980-11-15
DK352077A (da) 1978-02-07
LU77936A1 (sv) 1978-04-27
IL52615A (en) 1981-09-13
AR217080A1 (es) 1980-02-29
PT66891B (en) 1979-01-26
IE45505B1 (en) 1982-09-08
GR68688B (sv) 1982-02-01
JPS5321159A (en) 1978-02-27
GB1556569A (en) 1979-11-28
CH624934A5 (sv) 1981-08-31
SU818480A3 (ru) 1981-03-30
PT66891A (en) 1977-09-01
SU850000A3 (ru) 1981-07-23
AU2751577A (en) 1979-02-08
GB1556570A (en) 1979-11-28
FR2369260B1 (sv) 1982-02-12
FI70009B (fi) 1986-01-31
FI772376A (sv) 1978-02-07
DE2735904A1 (de) 1978-02-09
NL7708637A (nl) 1978-02-08
SE7708642L (sv) 1978-02-07
DD143768A5 (de) 1980-09-10
IL52615A0 (en) 1977-10-31
BE857506A (fr) 1978-02-06
FI70009C (fi) 1986-09-12
PL200124A1 (pl) 1978-05-22
PL112931B1 (en) 1980-11-29
AU508007B2 (en) 1980-03-06
YU192577A (en) 1983-04-30
DD136135A5 (de) 1979-06-20
FR2369260A1 (fr) 1978-05-26
ES471349A1 (es) 1979-09-16
NO772752L (no) 1978-02-07
JPS5531147B2 (sv) 1980-08-15
SE423813B (sv) 1982-06-07
JPS585196B2 (ja) 1983-01-29
AT362887B (de) 1981-06-25
IE45505L (en) 1978-02-06
NZ184806A (en) 1980-04-28
CA1077948A (en) 1980-05-20
CS221269B2 (en) 1983-04-29
ES461388A1 (es) 1978-12-01
SU703016A3 (ru) 1979-12-05
ZA774704B (en) 1978-06-28

Similar Documents

Publication Publication Date Title
US4177346A (en) 1,5-Disubstituted-2-pyrrolidones
EP0045118B1 (en) Intermediates for the synthesis of bicyclo (2,2,1) heptanes and bicyclo (2,2,1) hept-2z-enes
CA1088930A (en) Preparation of 9-hydroxy tetrahydropyranyl substituted prostaglandin intermediates
HU180273B (en) Process for producing 1,5-disubstituted-2-pyrrolidone derivatives
US4169895A (en) Antisecretory 16,16-dimethyl-17-oxaprostaglandins
HU205116B (en) Process for producing 1,4-diazabicyclo/3.2.2./nonane
HU190007B (en) Process for producing new aromatic prostacylin analogues
Boisbrun et al. A Convenient Synthesis of Indole‐Substituted 2‐Pyrrolidones and Their Cyclized Derivatives
US4095036A (en) 8β,12α,15β-PGF2 β Compounds
US4048194A (en) 6α-Methoxy-4α-hydroxy-2β-hydroxymethyl-3.alpha.-tetrahydropyranacetic acid 4α γ-lactone ethers and acylates
US4029693A (en) 2A,2B-Dihomo-11-deoxy-17(substituted phenyl)-18,19,20-trinor-PGE2 compounds and their corresponding esters
US4404372A (en) 15-Substituted-ω-pentanorprostaglandin derivatives
US3987085A (en) 8β,11β,12α-PGF2.sub.α compounds
US4298745A (en) Hydantoin derivatives
US4092349A (en) 11-Desoxy-15-thiaprostaglandins
KR810000657B1 (ko) 피롤리돈 화합물의 제조방법
US4035360A (en) Magnesium salts of 2-descarboxy-2-(tetrazol-5-yl)-11-desoxy-15-substituted-omega-pentanoprostaglandins
JPS60152461A (ja) ピロリジン誘導体
US3901919A (en) Bicyclononane diol and esters
DK146179B (da) 1,5-disubstituerede 3ae-oxo-2-pyrrolidon-forbindelser til anvendelse som mellemprodukter ved fremstilling af 1,5-disubstituerede 2-pyrrolidon-forbindelser
US4213907A (en) Prostaglandin intermediates
US5498719A (en) Diastereoselective process leading to a key intermediate for the preparation of fluorinated reverse transcriptase inhibitors
US4169849A (en) 11-desoxy-15-thiaprostaglandins
CA1186306A (en) Optically active 16-methoxy-16-methyl-prostaglandin e derivatives and a process for preparing them
US4148804A (en) 2-Descarboxy-2-(tetrazol-5-yl) 11-desoxy-15-thiaprostaglandins