HRP20201055T1 - Farmaceutske formulacije nitazoksanida s kontroliranim oslobađanjem - Google Patents

Farmaceutske formulacije nitazoksanida s kontroliranim oslobađanjem Download PDF

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Publication number
HRP20201055T1
HRP20201055T1 HRP20201055TT HRP20201055T HRP20201055T1 HR P20201055 T1 HRP20201055 T1 HR P20201055T1 HR P20201055T T HRP20201055T T HR P20201055TT HR P20201055 T HRP20201055 T HR P20201055T HR P20201055 T1 HRP20201055 T1 HR P20201055T1
Authority
HR
Croatia
Prior art keywords
nitazoxanide
preparation
polymorph
amide
ester
Prior art date
Application number
HRP20201055TT
Other languages
English (en)
Croatian (hr)
Inventor
Jean-Francois Rossignol
Marc Ayers
Original Assignee
Romark Laboratories, L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Romark Laboratories, L.C. filed Critical Romark Laboratories, L.C.
Publication of HRP20201055T1 publication Critical patent/HRP20201055T1/hr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HRP20201055TT 2009-02-13 2010-02-12 Farmaceutske formulacije nitazoksanida s kontroliranim oslobađanjem HRP20201055T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20228509P 2009-02-13 2009-02-13
PCT/US2010/024000 WO2010093854A1 (en) 2009-02-13 2010-02-12 Controlled release pharmaceutical formulations of nitazoxanide
EP10741758.6A EP2395840B1 (en) 2009-02-13 2010-02-12 Controlled release pharmaceutical formulations of nitazoxanide

Publications (1)

Publication Number Publication Date
HRP20201055T1 true HRP20201055T1 (hr) 2020-10-30

Family

ID=42560126

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20201055TT HRP20201055T1 (hr) 2009-02-13 2010-02-12 Farmaceutske formulacije nitazoksanida s kontroliranim oslobađanjem

Country Status (23)

Country Link
US (5) US8524278B2 (https=)
EP (1) EP2395840B1 (https=)
JP (3) JP5726766B2 (https=)
KR (1) KR101697800B1 (https=)
CN (2) CN102395276A (https=)
AU (3) AU2010213678B2 (https=)
BR (1) BRPI1007945C8 (https=)
CA (1) CA2752233C (https=)
CO (1) CO6501159A2 (https=)
CY (1) CY1123162T1 (https=)
DK (1) DK2395840T3 (https=)
EA (1) EA029018B1 (https=)
ES (1) ES2797493T3 (https=)
HR (1) HRP20201055T1 (https=)
HU (1) HUE049501T2 (https=)
IL (1) IL214624A0 (https=)
LT (1) LT2395840T (https=)
MX (2) MX381895B (https=)
PL (1) PL2395840T3 (https=)
PT (1) PT2395840T (https=)
SI (1) SI2395840T1 (https=)
UA (1) UA107564C2 (https=)
WO (1) WO2010093854A1 (https=)

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Also Published As

Publication number Publication date
BRPI1007945A2 (pt) 2015-09-01
EP2395840A1 (en) 2011-12-21
CO6501159A2 (es) 2012-08-15
EA029018B1 (ru) 2018-01-31
EA201190127A1 (ru) 2012-03-30
AU2010213678B2 (en) 2015-11-26
JP5726766B2 (ja) 2015-06-03
CN107260695A (zh) 2017-10-20
CY1123162T1 (el) 2021-10-29
IL214624A0 (en) 2011-09-27
CN102395276A (zh) 2012-03-28
EP2395840B1 (en) 2020-04-15
WO2010093854A1 (en) 2010-08-19
AU2016200971A1 (en) 2016-03-03
US20160243087A1 (en) 2016-08-25
US20180085353A1 (en) 2018-03-29
EP2395840A4 (en) 2013-12-25
MX381895B (es) 2025-03-13
US20140065215A1 (en) 2014-03-06
BRPI1007945B8 (pt) 2020-08-18
PT2395840T (pt) 2020-07-06
ES2797493T3 (es) 2020-12-02
US9351937B2 (en) 2016-05-31
US10383855B2 (en) 2019-08-20
AU2016200971B2 (en) 2017-02-23
DK2395840T3 (da) 2020-06-08
UA107564C2 (uk) 2015-01-26
JP6117845B2 (ja) 2017-04-19
US20190321338A1 (en) 2019-10-24
BRPI1007945C8 (pt) 2021-05-25
AU2017203148A1 (en) 2017-06-01
MX2011008530A (es) 2011-10-14
JP2017061561A (ja) 2017-03-30
KR20120008024A (ko) 2012-01-25
CA2752233C (en) 2017-01-03
AU2010213678A1 (en) 2011-09-01
PL2395840T3 (pl) 2020-09-07
US11426388B2 (en) 2022-08-30
JP2015143258A (ja) 2015-08-06
US20100209505A1 (en) 2010-08-19
HUE049501T2 (hu) 2020-09-28
SI2395840T1 (sl) 2020-08-31
US9827227B2 (en) 2017-11-28
BRPI1007945B1 (pt) 2020-08-04
KR101697800B1 (ko) 2017-01-18
AU2017203148B2 (en) 2018-08-09
CA2752233A1 (en) 2010-08-19
JP6491174B2 (ja) 2019-03-27
LT2395840T (lt) 2020-07-10
JP2012518002A (ja) 2012-08-09
US8524278B2 (en) 2013-09-03
MX348282B (es) 2017-06-05
BRPI1007945C1 (pt) 2020-09-01

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