MX348282B - Formulaciones farmaceuticas de liberacion controlada de nitazoxanida. - Google Patents

Formulaciones farmaceuticas de liberacion controlada de nitazoxanida.

Info

Publication number
MX348282B
MX348282B MX2011008530A MX2011008530A MX348282B MX 348282 B MX348282 B MX 348282B MX 2011008530 A MX2011008530 A MX 2011008530A MX 2011008530 A MX2011008530 A MX 2011008530A MX 348282 B MX348282 B MX 348282B
Authority
MX
Mexico
Prior art keywords
nitazoxanide
controlled release
pharmaceutical formulations
release pharmaceutical
analogue
Prior art date
Application number
MX2011008530A
Other languages
English (en)
Other versions
MX2011008530A (es
Inventor
Rossignol * Jean-Francois
Ayers Marc
Original Assignee
Romark Laboratories L C *
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Romark Laboratories L C * filed Critical Romark Laboratories L C *
Publication of MX2011008530A publication Critical patent/MX2011008530A/es
Publication of MX348282B publication Critical patent/MX348282B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Se proporcionan formulaciones de dosificación sólida de nitazoxanida, o un análogo de nitazoxanida que comprenden una porción de liberación controlada y una porción de liberación inmediata. La composición farmacéutica está típicamente en la forma de una forma de dosificación oral sólida de dos capas que comprende (a) una primera capa que comprende una primera cantidad de nitazoxanida o análogo de la misma en una formulación de liberación controlada, y (b) una segunda capa que comprende una segunda cantidad de nitazoxanida o un análogo de la misma en una formulación de liberación inmediata. También se proporciona el método de uso de las formulaciones en el tratamiento de la hepatitis C.
MX2011008530A 2009-02-13 2010-02-12 Formulaciones farmaceuticas de liberacion controlada de nitazoxanida. MX348282B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20228509P 2009-02-13 2009-02-13
PCT/US2010/024000 WO2010093854A1 (en) 2009-02-13 2010-02-12 Controlled release pharmaceutical formulations of nitazoxanide

Publications (2)

Publication Number Publication Date
MX2011008530A MX2011008530A (es) 2011-10-14
MX348282B true MX348282B (es) 2017-06-05

Family

ID=42560126

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017006915A MX381895B (es) 2009-02-13 2010-02-12 Formulaciones farmaceuticas de liberacion controlada de nitazoxanida.
MX2011008530A MX348282B (es) 2009-02-13 2010-02-12 Formulaciones farmaceuticas de liberacion controlada de nitazoxanida.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2017006915A MX381895B (es) 2009-02-13 2010-02-12 Formulaciones farmaceuticas de liberacion controlada de nitazoxanida.

Country Status (23)

Country Link
US (5) US8524278B2 (es)
EP (1) EP2395840B1 (es)
JP (3) JP5726766B2 (es)
KR (1) KR101697800B1 (es)
CN (2) CN107260695A (es)
AU (3) AU2010213678B2 (es)
BR (1) BRPI1007945C8 (es)
CA (1) CA2752233C (es)
CO (1) CO6501159A2 (es)
CY (1) CY1123162T1 (es)
DK (1) DK2395840T3 (es)
EA (1) EA029018B1 (es)
ES (1) ES2797493T3 (es)
HR (1) HRP20201055T1 (es)
HU (1) HUE049501T2 (es)
IL (1) IL214624A0 (es)
LT (1) LT2395840T (es)
MX (2) MX381895B (es)
PL (1) PL2395840T3 (es)
PT (1) PT2395840T (es)
SI (1) SI2395840T1 (es)
UA (1) UA107564C2 (es)
WO (1) WO2010093854A1 (es)

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Also Published As

Publication number Publication date
BRPI1007945B1 (pt) 2020-08-04
WO2010093854A1 (en) 2010-08-19
HUE049501T2 (hu) 2020-09-28
PT2395840T (pt) 2020-07-06
KR20120008024A (ko) 2012-01-25
MX2011008530A (es) 2011-10-14
AU2016200971B2 (en) 2017-02-23
ES2797493T3 (es) 2020-12-02
US10383855B2 (en) 2019-08-20
JP5726766B2 (ja) 2015-06-03
US20180085353A1 (en) 2018-03-29
JP6117845B2 (ja) 2017-04-19
JP2017061561A (ja) 2017-03-30
IL214624A0 (en) 2011-09-27
EP2395840A4 (en) 2013-12-25
CN102395276A (zh) 2012-03-28
CA2752233C (en) 2017-01-03
AU2010213678A1 (en) 2011-09-01
EP2395840B1 (en) 2020-04-15
CO6501159A2 (es) 2012-08-15
LT2395840T (lt) 2020-07-10
MX381895B (es) 2025-03-13
JP6491174B2 (ja) 2019-03-27
DK2395840T3 (da) 2020-06-08
KR101697800B1 (ko) 2017-01-18
US11426388B2 (en) 2022-08-30
US20140065215A1 (en) 2014-03-06
US20190321338A1 (en) 2019-10-24
CY1123162T1 (el) 2021-10-29
AU2017203148B2 (en) 2018-08-09
PL2395840T3 (pl) 2020-09-07
EP2395840A1 (en) 2011-12-21
CA2752233A1 (en) 2010-08-19
US8524278B2 (en) 2013-09-03
EA029018B1 (ru) 2018-01-31
CN107260695A (zh) 2017-10-20
BRPI1007945A2 (pt) 2015-09-01
SI2395840T1 (sl) 2020-08-31
HRP20201055T1 (hr) 2020-10-30
US20160243087A1 (en) 2016-08-25
US9827227B2 (en) 2017-11-28
US9351937B2 (en) 2016-05-31
BRPI1007945C1 (pt) 2020-09-01
BRPI1007945B8 (pt) 2020-08-18
AU2016200971A1 (en) 2016-03-03
UA107564C2 (uk) 2015-01-26
AU2017203148A1 (en) 2017-06-01
EA201190127A1 (ru) 2012-03-30
BRPI1007945C8 (pt) 2021-05-25
AU2010213678B2 (en) 2015-11-26
JP2015143258A (ja) 2015-08-06
US20100209505A1 (en) 2010-08-19
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