HRP20180468T1 - Novi derivat analoga inzulina - Google Patents

Novi derivat analoga inzulina Download PDF

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Publication number
HRP20180468T1
HRP20180468T1 HRP20180468TT HRP20180468T HRP20180468T1 HR P20180468 T1 HRP20180468 T1 HR P20180468T1 HR P20180468T T HRP20180468T T HR P20180468TT HR P20180468 T HRP20180468 T HR P20180468T HR P20180468 T1 HRP20180468 T1 HR P20180468T1
Authority
HR
Croatia
Prior art keywords
compound
administered
compound according
diabetes
treatment
Prior art date
Application number
HRP20180468TT
Other languages
English (en)
Croatian (hr)
Inventor
Peter Madsen
Tina Møller TAGMOSE
Helle Naver
Thomas Børglum KJELDSEN
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of HRP20180468T1 publication Critical patent/HRP20180468T1/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HRP20180468TT 2013-10-07 2014-10-03 Novi derivat analoga inzulina HRP20180468T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13187626 2013-10-07
EP14780512.1A EP3055325B1 (en) 2013-10-07 2014-10-03 Novel derivative of an insulin analogue
PCT/EP2014/071236 WO2015052088A1 (en) 2013-10-07 2014-10-03 Novel derivative of an insulin analogue

Publications (1)

Publication Number Publication Date
HRP20180468T1 true HRP20180468T1 (hr) 2018-05-04

Family

ID=49301382

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20180468TT HRP20180468T1 (hr) 2013-10-07 2014-10-03 Novi derivat analoga inzulina

Country Status (21)

Country Link
US (1) US9896496B2 (enExample)
EP (1) EP3055325B1 (enExample)
JP (1) JP6499184B2 (enExample)
KR (1) KR20160065126A (enExample)
CN (1) CN105636979B (enExample)
AU (1) AU2014333979B2 (enExample)
BR (1) BR112016007166A2 (enExample)
CA (1) CA2926701A1 (enExample)
DK (1) DK3055325T3 (enExample)
ES (1) ES2676065T3 (enExample)
HR (1) HRP20180468T1 (enExample)
HU (1) HUE036702T2 (enExample)
IL (1) IL244507B (enExample)
MX (1) MX366636B (enExample)
PL (1) PL3055325T3 (enExample)
PT (1) PT3055325T (enExample)
RS (1) RS57004B1 (enExample)
RU (1) RU2673185C2 (enExample)
SA (1) SA516370893B1 (enExample)
SI (1) SI3055325T1 (enExample)
WO (1) WO2015052088A1 (enExample)

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WO2018083335A1 (en) 2016-11-07 2018-05-11 Novo Nordisk A/S Dchbs-active esters of peg compounds and their use
BR112019011761A2 (pt) * 2016-12-16 2019-11-05 Novo Nordisk As composições farmacêuticas contendo insulina
KR102612576B1 (ko) 2017-09-29 2023-12-12 한미약품 주식회사 링커로서 비펩타이드성 중합체 결합 지방산 유도체 화합물을 포함하는 단백질 결합체 및 이의 제조방법
TWI799680B (zh) * 2019-01-29 2023-04-21 美商美國禮來大藥廠 製備gip/glp1雙重促效劑之方法
CN111909255A (zh) * 2019-05-10 2020-11-10 宁波鲲鹏生物科技有限公司 胰岛素衍生物及其制备方法
CA3189527A1 (en) 2020-07-24 2022-01-27 Jiangsu Gensciences Inc. Insulin-fc fusion protein and application thereof
US20240374692A1 (en) 2021-05-24 2024-11-14 Sunshine Lake Pharma Co., Ltd. A novel acylated insulin analog
CN117342967A (zh) * 2023-09-28 2024-01-05 奥锐特药业(天津)有限公司 一种长链脂肪酸化合物的制备方法

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JP5931857B2 (ja) 2010-06-23 2016-06-08 ノヴォ ノルディスク アー／エス 追加のジスルフィド結合を含有するインスリン誘導体
EP2632478B1 (en) * 2010-10-27 2019-07-24 Novo Nordisk A/S Treating diabetes melitus using insulin injections administered with varying injection intervals
AU2013247047A1 (en) 2012-04-11 2014-10-23 Novo Nordisk A/S Insulin formulations

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BR112016007166A2 (pt) 2017-09-12
PL3055325T3 (pl) 2018-06-29
AU2014333979B2 (en) 2018-02-15
EP3055325A1 (en) 2016-08-17
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SA516370893B1 (ar) 2018-08-13
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