HRP20160414T1 - Postupak sinteze derivata 3,6-dihidro-1,3,5-triazina - Google Patents

Postupak sinteze derivata 3,6-dihidro-1,3,5-triazina Download PDF

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Publication number
HRP20160414T1
HRP20160414T1 HRP20160414TT HRP20160414T HRP20160414T1 HR P20160414 T1 HRP20160414 T1 HR P20160414T1 HR P20160414T T HRP20160414T T HR P20160414TT HR P20160414 T HRP20160414 T HR P20160414T HR P20160414 T1 HRP20160414 T1 HR P20160414T1
Authority
HR
Croatia
Prior art keywords
process according
compound
formula
butanol
solvent
Prior art date
Application number
HRP20160414TT
Other languages
English (en)
Croatian (hr)
Inventor
Stéphanie AUBOURG
Bernard Boudet
Daniel Cravo
Matthias Helmreich
Original Assignee
Poxel Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poxel Sas filed Critical Poxel Sas
Publication of HRP20160414T1 publication Critical patent/HRP20160414T1/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/10—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HRP20160414TT 2008-05-23 2009-04-24 Postupak sinteze derivata 3,6-dihidro-1,3,5-triazina HRP20160414T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08009483 2008-05-23
PCT/EP2009/002997 WO2009141040A2 (en) 2008-05-23 2009-04-24 Process for the synthesis of 3,6-dihydro-1,3,5-triazine derivatives
EP09749530.3A EP2300444B1 (en) 2008-05-23 2009-04-24 Process for the synthesis of 3,6-dihydro-1,3,5-triazine derivatives

Publications (1)

Publication Number Publication Date
HRP20160414T1 true HRP20160414T1 (hr) 2016-05-20

Family

ID=40791625

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20160414TT HRP20160414T1 (hr) 2008-05-23 2009-04-24 Postupak sinteze derivata 3,6-dihidro-1,3,5-triazina

Country Status (21)

Country Link
US (1) US20110124860A1 (enExample)
EP (1) EP2300444B1 (enExample)
JP (1) JP5458093B2 (enExample)
KR (1) KR101618198B1 (enExample)
CN (1) CN102036970A (enExample)
AU (1) AU2009250149B2 (enExample)
BR (1) BRPI0912512B1 (enExample)
CA (1) CA2725011A1 (enExample)
CY (1) CY1117855T1 (enExample)
DK (1) DK2300444T3 (enExample)
EA (1) EA018921B1 (enExample)
ES (1) ES2571793T3 (enExample)
HR (1) HRP20160414T1 (enExample)
HU (1) HUE027532T2 (enExample)
IL (1) IL209198A (enExample)
MX (1) MX2010012741A (enExample)
PL (1) PL2300444T3 (enExample)
RS (1) RS54736B1 (enExample)
SI (1) SI2300444T1 (enExample)
WO (1) WO2009141040A2 (enExample)
ZA (1) ZA201009160B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2646422T3 (pl) 2010-12-01 2015-12-31 Poxel Rozdział enancjomerów pochodnych triazyny z zastosowaniem kwasu winowego
CN105753801B (zh) * 2016-03-25 2018-06-01 浙江工业大学 一种均三嗪类化合物的制备方法
JP2020536121A (ja) 2017-10-02 2020-12-10 ポクセルＰｏｘｅｌ 駆出率が保持された心不全を治療する方法
CA3102412A1 (en) 2018-06-06 2019-12-12 Metavant Sciences Gmbh Methods of treating subjects having diabetes with chronic kidney disease
WO2019238647A1 (en) 2018-06-14 2019-12-19 Poxel Film-coated tablet comprising a triazine derivative for use in the treatment of diabetes
CN114681464B (zh) * 2020-12-28 2024-07-09 南京理工大学 二甲双胍类似物在制备脑缺血再灌注损伤预防和治疗药物中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2804113B1 (fr) * 2000-01-26 2004-06-18 Lipha Derives animes de dihydro-1,3,5-triazine et leurs applications en therapeutique
AU2003289375A1 (en) * 2002-12-17 2004-07-09 Hamari Chemicals, Ltd Novel 2,4-diamino-1,3,5-triazine derivative
FR2853650B1 (fr) * 2003-04-10 2006-07-07 Merck Sante Sas Procede de dedoublement d'amines utiles pour le traitement de desordres associes au syndrome d'insulino-resistance
DE102007054416A1 (de) * 2007-11-13 2009-05-14 Studiengesellschaft Kohle Mbh Verfahren zur Herstellung von 3,6-Dihydro-1,3,5- Triazin-Derivaten für die Behandlungen von Erkrankungen, die mit dem Insulinresistenz-Syndrom assoziiert sind

Also Published As

Publication number Publication date
WO2009141040A2 (en) 2009-11-26
PL2300444T3 (pl) 2016-08-31
JP2011520930A (ja) 2011-07-21
SI2300444T1 (sl) 2016-10-28
WO2009141040A3 (en) 2010-01-21
MX2010012741A (es) 2010-12-21
KR101618198B1 (ko) 2016-05-04
AU2009250149A1 (en) 2009-11-26
EA201001828A1 (ru) 2011-04-29
JP5458093B2 (ja) 2014-04-02
BRPI0912512B1 (pt) 2018-09-11
EP2300444A2 (en) 2011-03-30
DK2300444T3 (en) 2016-05-23
IL209198A0 (en) 2011-01-31
CN102036970A (zh) 2011-04-27
CA2725011A1 (en) 2009-11-26
KR20110013498A (ko) 2011-02-09
EA018921B1 (ru) 2013-11-29
US20110124860A1 (en) 2011-05-26
HUE027532T2 (en) 2016-10-28
EP2300444B1 (en) 2016-04-13
CY1117855T1 (el) 2017-05-17
BRPI0912512A2 (pt) 2015-07-28
RS54736B1 (sr) 2016-10-31
ES2571793T3 (es) 2016-05-26
AU2009250149B2 (en) 2013-05-23
IL209198A (en) 2013-11-28
ZA201009160B (en) 2011-10-26

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