AU2009250149B2 - Process for the synthesis of 3,6-dihydro-1,3,5-triazine derivatives - Google Patents

Process for the synthesis of 3,6-dihydro-1,3,5-triazine derivatives Download PDF

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Publication number
AU2009250149B2
AU2009250149B2 AU2009250149A AU2009250149A AU2009250149B2 AU 2009250149 B2 AU2009250149 B2 AU 2009250149B2 AU 2009250149 A AU2009250149 A AU 2009250149A AU 2009250149 A AU2009250149 A AU 2009250149A AU 2009250149 B2 AU2009250149 B2 AU 2009250149B2
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AU
Australia
Prior art keywords
formula
process according
compound
base
butanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2009250149A
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English (en)
Other versions
AU2009250149A1 (en
Inventor
Stephanie Aubourg
Bernard Boudet
Daniel Cravo
Matthias Helmreich
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Poxel SA
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Poxel SA
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Publication date
Application filed by Poxel SA filed Critical Poxel SA
Publication of AU2009250149A1 publication Critical patent/AU2009250149A1/en
Application granted granted Critical
Publication of AU2009250149B2 publication Critical patent/AU2009250149B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/10—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2009250149A 2008-05-23 2009-04-24 Process for the synthesis of 3,6-dihydro-1,3,5-triazine derivatives Ceased AU2009250149B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08009483.2 2008-05-23
EP08009483 2008-05-23
PCT/EP2009/002997 WO2009141040A2 (en) 2008-05-23 2009-04-24 Process for the synthesis of 3,6-dihydro-1,3,5-triazine derivatives

Publications (2)

Publication Number Publication Date
AU2009250149A1 AU2009250149A1 (en) 2009-11-26
AU2009250149B2 true AU2009250149B2 (en) 2013-05-23

Family

ID=40791625

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009250149A Ceased AU2009250149B2 (en) 2008-05-23 2009-04-24 Process for the synthesis of 3,6-dihydro-1,3,5-triazine derivatives

Country Status (21)

Country Link
US (1) US20110124860A1 (enExample)
EP (1) EP2300444B1 (enExample)
JP (1) JP5458093B2 (enExample)
KR (1) KR101618198B1 (enExample)
CN (1) CN102036970A (enExample)
AU (1) AU2009250149B2 (enExample)
BR (1) BRPI0912512B1 (enExample)
CA (1) CA2725011A1 (enExample)
CY (1) CY1117855T1 (enExample)
DK (1) DK2300444T3 (enExample)
EA (1) EA018921B1 (enExample)
ES (1) ES2571793T3 (enExample)
HR (1) HRP20160414T1 (enExample)
HU (1) HUE027532T2 (enExample)
IL (1) IL209198A (enExample)
MX (1) MX2010012741A (enExample)
PL (1) PL2300444T3 (enExample)
RS (1) RS54736B1 (enExample)
SI (1) SI2300444T1 (enExample)
WO (1) WO2009141040A2 (enExample)
ZA (1) ZA201009160B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2646422T3 (pl) 2010-12-01 2015-12-31 Poxel Rozdział enancjomerów pochodnych triazyny z zastosowaniem kwasu winowego
CN105753801B (zh) * 2016-03-25 2018-06-01 浙江工业大学 一种均三嗪类化合物的制备方法
JP2020536121A (ja) 2017-10-02 2020-12-10 ポクセルＰｏｘｅｌ 駆出率が保持された心不全を治療する方法
CA3102412A1 (en) 2018-06-06 2019-12-12 Metavant Sciences Gmbh Methods of treating subjects having diabetes with chronic kidney disease
WO2019238647A1 (en) 2018-06-14 2019-12-19 Poxel Film-coated tablet comprising a triazine derivative for use in the treatment of diabetes
CN114681464B (zh) * 2020-12-28 2024-07-09 南京理工大学 二甲双胍类似物在制备脑缺血再灌注损伤预防和治疗药物中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001055122A1 (fr) * 2000-01-26 2001-08-02 Lipha Derives amines de dihydro-1,3,5-triazine et leurs applications en therapeutique
WO2009062483A2 (de) * 2007-11-13 2009-05-22 Studiengesellschaft Kohle Mbh Verfahren zur herstellung von 3,6-dihydro-1,3,5-triazin-derivaten

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003289375A1 (en) * 2002-12-17 2004-07-09 Hamari Chemicals, Ltd Novel 2,4-diamino-1,3,5-triazine derivative
FR2853650B1 (fr) * 2003-04-10 2006-07-07 Merck Sante Sas Procede de dedoublement d'amines utiles pour le traitement de desordres associes au syndrome d'insulino-resistance

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001055122A1 (fr) * 2000-01-26 2001-08-02 Lipha Derives amines de dihydro-1,3,5-triazine et leurs applications en therapeutique
WO2009062483A2 (de) * 2007-11-13 2009-05-22 Studiengesellschaft Kohle Mbh Verfahren zur herstellung von 3,6-dihydro-1,3,5-triazin-derivaten

Also Published As

Publication number Publication date
WO2009141040A2 (en) 2009-11-26
PL2300444T3 (pl) 2016-08-31
JP2011520930A (ja) 2011-07-21
SI2300444T1 (sl) 2016-10-28
WO2009141040A3 (en) 2010-01-21
MX2010012741A (es) 2010-12-21
KR101618198B1 (ko) 2016-05-04
AU2009250149A1 (en) 2009-11-26
EA201001828A1 (ru) 2011-04-29
JP5458093B2 (ja) 2014-04-02
BRPI0912512B1 (pt) 2018-09-11
EP2300444A2 (en) 2011-03-30
DK2300444T3 (en) 2016-05-23
IL209198A0 (en) 2011-01-31
CN102036970A (zh) 2011-04-27
CA2725011A1 (en) 2009-11-26
KR20110013498A (ko) 2011-02-09
EA018921B1 (ru) 2013-11-29
US20110124860A1 (en) 2011-05-26
HUE027532T2 (en) 2016-10-28
EP2300444B1 (en) 2016-04-13
HRP20160414T1 (hr) 2016-05-20
CY1117855T1 (el) 2017-05-17
BRPI0912512A2 (pt) 2015-07-28
RS54736B1 (sr) 2016-10-31
ES2571793T3 (es) 2016-05-26
IL209198A (en) 2013-11-28
ZA201009160B (en) 2011-10-26

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired