HRP20160002T1 - Bicikliäśki heterocikliäśki spojevi kao inhibitori protein tirozin kinaze - Google Patents

Bicikliäśki heterocikliäśki spojevi kao inhibitori protein tirozin kinaze Download PDF

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Publication number
HRP20160002T1
HRP20160002T1 HRP20160002TT HRP20160002T HRP20160002T1 HR P20160002 T1 HRP20160002 T1 HR P20160002T1 HR P20160002T T HRP20160002T T HR P20160002TT HR P20160002 T HRP20160002 T HR P20160002T HR P20160002 T1 HRP20160002 T1 HR P20160002T1
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HR
Croatia
Prior art keywords
alkyl
heterocyclyl
compound according
groups
independently represent
Prior art date
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HRP20160002TT
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English (en)
Croatian (hr)
Inventor
Gordon Saxty
Valerio Berdini
Christopher William Murray
Charlotte Mary Griffiths-Jones
Emma Vickerstaffe
Gilbert Ebai Besong
Maria Grazia Carr
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Astex Therapeutics Limited
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Application filed by Astex Therapeutics Limited filed Critical Astex Therapeutics Limited
Publication of HRP20160002T1 publication Critical patent/HRP20160002T1/hr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HRP20160002TT 2007-10-12 2008-10-10 Bicikliäśki heterocikliäśki spojevi kao inhibitori protein tirozin kinaze HRP20160002T1 (hr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US97955507P 2007-10-12 2007-10-12
GBGB0720041.3A GB0720041D0 (en) 2007-10-12 2007-10-12 New Compounds
US6117808P 2008-06-13 2008-06-13
PCT/GB2008/003418 WO2009047506A1 (en) 2007-10-12 2008-10-10 Bicyclic heterocyclic compounds as protein tyrosine kinase inhibitors
EP08806556.0A EP2197880B1 (en) 2007-10-12 2008-10-10 Bicyclic heterocyclic compounds as protein tyrosine kinase inhibitors

Publications (1)

Publication Number Publication Date
HRP20160002T1 true HRP20160002T1 (hr) 2016-03-11

Family

ID=38788133

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20160002TT HRP20160002T1 (hr) 2007-10-12 2008-10-10 Bicikliäśki heterocikliäśki spojevi kao inhibitori protein tirozin kinaze

Country Status (17)

Country Link
US (2) US8076354B2 (enExample)
EP (1) EP2197880B1 (enExample)
JP (1) JP5497648B2 (enExample)
AU (1) AU2008309418B2 (enExample)
CA (1) CA2701865C (enExample)
CY (1) CY1117139T1 (enExample)
DK (1) DK2197880T3 (enExample)
ES (1) ES2559685T3 (enExample)
GB (1) GB0720041D0 (enExample)
HR (1) HRP20160002T1 (enExample)
HU (1) HUE026275T2 (enExample)
ME (1) ME02373B (enExample)
PL (1) PL2197880T3 (enExample)
PT (1) PT2197880E (enExample)
RS (1) RS54518B1 (enExample)
SI (1) SI2197880T1 (enExample)
WO (1) WO2009047506A1 (enExample)

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WO2009047506A1 (en) 2009-04-16
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