HRP20140808T1 - Fosfaplatine i njihova uporaba za lijeäśenje raka rezistentnog na cisplantin i karboplatin - Google Patents
Fosfaplatine i njihova uporaba za lijeäśenje raka rezistentnog na cisplantin i karboplatin Download PDFInfo
- Publication number
- HRP20140808T1 HRP20140808T1 HRP20140808AT HRP20140808T HRP20140808T1 HR P20140808 T1 HRP20140808 T1 HR P20140808T1 HR P20140808A T HRP20140808A T HR P20140808AT HR P20140808 T HRP20140808 T HR P20140808T HR P20140808 T1 HRP20140808 T1 HR P20140808T1
- Authority
- HR
- Croatia
- Prior art keywords
- platinum
- trans
- isolated
- preparation
- complex
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
- A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95412607P | 2007-08-06 | 2007-08-06 | |
| US97392607P | 2007-09-20 | 2007-09-20 | |
| PCT/US2008/072398 WO2009021082A2 (en) | 2007-08-06 | 2008-08-06 | Phosphaplatins and their use in the treatment of cancers resistant to cisplantin and carboplatin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20140808T1 true HRP20140808T1 (hr) | 2014-10-24 |
Family
ID=40342030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20140808AT HRP20140808T1 (hr) | 2007-08-06 | 2008-08-06 | Fosfaplatine i njihova uporaba za lijeäśenje raka rezistentnog na cisplantin i karboplatin |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US7700649B2 (enExample) |
| EP (2) | EP2173337B1 (enExample) |
| JP (2) | JP5385274B2 (enExample) |
| CN (1) | CN101801369B (enExample) |
| CY (1) | CY1115504T1 (enExample) |
| DK (1) | DK2173337T3 (enExample) |
| ES (1) | ES2495743T3 (enExample) |
| HR (1) | HRP20140808T1 (enExample) |
| PL (1) | PL2173337T3 (enExample) |
| PT (1) | PT2173337E (enExample) |
| SI (1) | SI2173337T1 (enExample) |
| WO (2) | WO2009021081A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101801369B (zh) | 2007-08-06 | 2012-09-19 | 俄亥俄大学 | 磷铂及其在治疗顺铂和卡铂耐药性癌中的用途 |
| PT2575802T (pt) * | 2010-06-04 | 2016-12-27 | Univ Ohio | Fosfaplatinas e sua utilização para o tratamento de cancros |
| CA2818933A1 (en) * | 2011-01-12 | 2012-07-19 | Ohio University | Phosphaplatins having anti-angiogenic, anti-metastatic, and pro-apoptotic properties and uses thereof |
| WO2013009511A1 (en) | 2011-07-08 | 2013-01-17 | Dow Global Technologies Llc | Polyethylene blend composition suitable for blown film, method of producing the same, and films made therefrom |
| JP6027619B2 (ja) | 2011-10-05 | 2016-11-16 | ラシンドラ・エヌ・ボーズ | ホスファプラチン系抗腫瘍剤の大規模調製のための効率的プロセス |
| CA2851254A1 (en) * | 2011-10-05 | 2013-04-11 | The University Of Houston System | Efficient processes for large scale preparation of phophaplatins antitumor agents |
| AU2012325819B2 (en) | 2011-10-20 | 2017-08-03 | Nerium Biotechnology, Inc. | Therapeutic combination for the treatment of cancer |
| EP2855496B1 (en) * | 2012-05-24 | 2016-12-14 | Phosplatin Therapeutics LLC | Synthetic and purification methods for phosphaplatin compounds and uses thereof |
| WO2014130776A1 (en) | 2013-02-22 | 2014-08-28 | University Of Houston | Phosphaplatins as neuroprotective agents |
| US20150231151A1 (en) * | 2014-02-19 | 2015-08-20 | University Of Houston System | Compositions and methods for the treatment of neurodegenerative diseases |
| KR102412203B1 (ko) | 2014-06-11 | 2022-06-23 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 백금 내성을 극복하는데 이용하기 위한 텍사피린-pt(iv) 접합체 및 조성물 |
| WO2017116356A1 (en) | 2015-12-30 | 2017-07-06 | Atilim Universitesi | Dna targeted mono and heterodinuclear complexes |
| KR102718532B1 (ko) * | 2017-01-06 | 2024-10-21 | 프로몬토리 테라퓨틱스 인코포레이티드 | 뼈 또는 혈액 암의 치료를 위한 치료제로서의 포스파플라틴 화합물 |
| JP7381083B2 (ja) * | 2017-09-08 | 2023-11-15 | フォスプラティン テラピューティクス インコーポレイテッド | 免疫調節剤としてのホスファプラチン化合物およびその治療的使用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4234500A (en) * | 1979-03-07 | 1980-11-18 | Engelhard Minerals & Chemicals Corporation | Ethylenediamine platinum(II) and 1,2-diamino-cyclohexane platinum(II) pyrophosphate complexes |
| US4291027A (en) * | 1979-03-07 | 1981-09-22 | Engelhard Minerals & Chemicals Corp. | Method for treating tumors with ethylenediamine platinum (II) and 1,2-diaminocyclohexane-platinum (II) pyrophosphate complexes |
| CA2017739A1 (en) * | 1989-07-18 | 1991-01-18 | Engelhard Corporation | Cis-diamineplatinum complexes with methanediphosphonate and substituted methanediphosphonate ligands as antitumor agents |
| WO2005000858A2 (en) * | 2003-06-27 | 2005-01-06 | Akira Odani | Bisphosphonate complexes |
| WO2009008345A1 (ja) * | 2007-07-06 | 2009-01-15 | Tmrc Co., Ltd. | 金属錯体化合物、これを有効成分とする癌治療剤組成物および該金属錯体化合物用の中間体 |
| CN101801369B (zh) | 2007-08-06 | 2012-09-19 | 俄亥俄大学 | 磷铂及其在治疗顺铂和卡铂耐药性癌中的用途 |
-
2008
- 2008-08-06 CN CN2008801015774A patent/CN101801369B/zh active Active
- 2008-08-06 SI SI200831280T patent/SI2173337T1/sl unknown
- 2008-08-06 PL PL08797320T patent/PL2173337T3/pl unknown
- 2008-08-06 HR HRP20140808AT patent/HRP20140808T1/hr unknown
- 2008-08-06 ES ES08797320.2T patent/ES2495743T3/es active Active
- 2008-08-06 US US12/187,376 patent/US7700649B2/en active Active
- 2008-08-06 PT PT87973202T patent/PT2173337E/pt unknown
- 2008-08-06 WO PCT/US2008/072397 patent/WO2009021081A2/en not_active Ceased
- 2008-08-06 EP EP08797320.2A patent/EP2173337B1/en active Active
- 2008-08-06 DK DK08797320.2T patent/DK2173337T3/da active
- 2008-08-06 EP EP13182512.7A patent/EP2668949A1/en not_active Withdrawn
- 2008-08-06 WO PCT/US2008/072398 patent/WO2009021082A2/en not_active Ceased
- 2008-08-06 JP JP2010520294A patent/JP5385274B2/ja active Active
-
2010
- 2010-03-11 US US12/722,189 patent/US8034964B2/en active Active
-
2011
- 2011-08-30 US US13/221,458 patent/US8445710B2/en active Active
-
2013
- 2013-03-15 US US13/842,885 patent/US8653132B2/en active Active
- 2013-06-07 JP JP2013120309A patent/JP5647300B2/ja active Active
-
2014
- 2014-08-27 CY CY20141100686T patent/CY1115504T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2173337A4 (en) | 2010-10-27 |
| US7700649B2 (en) | 2010-04-20 |
| JP2013227218A (ja) | 2013-11-07 |
| EP2173337A2 (en) | 2010-04-14 |
| ES2495743T3 (es) | 2014-09-17 |
| US20110313182A1 (en) | 2011-12-22 |
| US8445710B2 (en) | 2013-05-21 |
| SI2173337T1 (sl) | 2014-10-30 |
| DK2173337T3 (da) | 2014-09-15 |
| PL2173337T3 (pl) | 2014-11-28 |
| WO2009021082A3 (en) | 2009-04-23 |
| JP5647300B2 (ja) | 2014-12-24 |
| JP5385274B2 (ja) | 2014-01-08 |
| WO2009021081A3 (en) | 2009-05-07 |
| CN101801369A (zh) | 2010-08-11 |
| US20090042838A1 (en) | 2009-02-12 |
| US20130237503A1 (en) | 2013-09-12 |
| PT2173337E (pt) | 2014-09-03 |
| US8653132B2 (en) | 2014-02-18 |
| EP2173337B1 (en) | 2014-07-30 |
| CY1115504T1 (el) | 2017-01-04 |
| US8034964B2 (en) | 2011-10-11 |
| JP2010535803A (ja) | 2010-11-25 |
| WO2009021081A2 (en) | 2009-02-12 |
| CN101801369B (zh) | 2012-09-19 |
| HK1143551A1 (en) | 2011-01-07 |
| EP2668949A1 (en) | 2013-12-04 |
| WO2009021082A2 (en) | 2009-02-12 |
| US20100233293A1 (en) | 2010-09-16 |
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