SI2173337T1 - Fosfaplatini in njihova uporaba pri zdravljenju vrst raka, odpornih proti cisplatinu in karboplatinu - Google Patents

Fosfaplatini in njihova uporaba pri zdravljenju vrst raka, odpornih proti cisplatinu in karboplatinu

Info

Publication number
SI2173337T1
SI2173337T1 SI200831280T SI200831280T SI2173337T1 SI 2173337 T1 SI2173337 T1 SI 2173337T1 SI 200831280 T SI200831280 T SI 200831280T SI 200831280 T SI200831280 T SI 200831280T SI 2173337 T1 SI2173337 T1 SI 2173337T1
Authority
SI
Slovenia
Prior art keywords
phosphaplatins
cisplantin
carboplatin
treatment
cancers resistant
Prior art date
Application number
SI200831280T
Other languages
English (en)
Slovenian (sl)
Inventor
Rathindra N. Bose
Original Assignee
Ohio University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ohio University filed Critical Ohio University
Publication of SI2173337T1 publication Critical patent/SI2173337T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI200831280T 2007-08-06 2008-08-06 Fosfaplatini in njihova uporaba pri zdravljenju vrst raka, odpornih proti cisplatinu in karboplatinu SI2173337T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US95412607P 2007-08-06 2007-08-06
US97392607P 2007-09-20 2007-09-20
PCT/US2008/072398 WO2009021082A2 (en) 2007-08-06 2008-08-06 Phosphaplatins and their use in the treatment of cancers resistant to cisplantin and carboplatin
EP08797320.2A EP2173337B1 (en) 2007-08-06 2008-08-06 Phosphaplatins and their use in the treatment of cancers resistant to cisplantin and carboplatin

Publications (1)

Publication Number Publication Date
SI2173337T1 true SI2173337T1 (sl) 2014-10-30

Family

ID=40342030

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200831280T SI2173337T1 (sl) 2007-08-06 2008-08-06 Fosfaplatini in njihova uporaba pri zdravljenju vrst raka, odpornih proti cisplatinu in karboplatinu

Country Status (12)

Country Link
US (4) US7700649B2 (enExample)
EP (2) EP2668949A1 (enExample)
JP (2) JP5385274B2 (enExample)
CN (1) CN101801369B (enExample)
CY (1) CY1115504T1 (enExample)
DK (1) DK2173337T3 (enExample)
ES (1) ES2495743T3 (enExample)
HR (1) HRP20140808T1 (enExample)
PL (1) PL2173337T3 (enExample)
PT (1) PT2173337E (enExample)
SI (1) SI2173337T1 (enExample)
WO (2) WO2009021081A2 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2173337T3 (pl) 2007-08-06 2014-11-28 Univ Ohio Fosfaplatyny i ich zastosowanie w leczeniu raków opornych na cisplatynę i karboplatynę
JP5860872B2 (ja) * 2010-06-04 2016-02-16 オハイオ ユニバーシティー ホスファプラチン、及び癌治療のためのそれらの使用
EP2663301A1 (en) 2011-01-12 2013-11-20 Ohio University Phosphaplatins having anti-angiogenic, anti-metastatic, and pro-apoptotic properties and uses thereof
MX354678B (es) 2011-07-08 2018-03-15 Dow Global Technologies Llc Composicion de mezcla de polietileno adecuada para pelicula soplada, metodo para producir la misma y peliculas hechas a partir de la misma.
CA2851254A1 (en) * 2011-10-05 2013-04-11 The University Of Houston System Efficient processes for large scale preparation of phophaplatins antitumor agents
MX357865B (es) 2011-10-05 2018-07-25 N Bose Rathindra Procedimientos eficientes para preparación a gran escala de agentes antitumorales de fosfaplatinos.
EP2768498B1 (en) 2011-10-20 2020-03-04 Nerium Biotechnology, Inc. Therapeutic combination for the treatment of cancer
PT3202769T (pt) 2012-05-24 2019-10-31 Phosplatin Therapeutics Llc Processos de síntese e de purificação para compostos de fosfaplatina e aplicações dos mesmos
US9333211B2 (en) * 2013-02-22 2016-05-10 University Of Houston System Phosphaplatin mediated modulation of pigment epithelial derived factor and uses thereof
US20150231151A1 (en) * 2014-02-19 2015-08-20 University Of Houston System Compositions and methods for the treatment of neurodegenerative diseases
SG11201610306RA (en) 2014-06-11 2017-01-27 Univ Texas Texaphyrin-pt(iv) conjugates and compositions for use in overcoming platinum resistance
EP3397642A1 (en) 2015-12-30 2018-11-07 Atilim Universitesi Dna targeted mono and heterodinuclear complexes
KR102419247B1 (ko) 2016-04-06 2022-07-11 포스플라틴 테라퓨틱스 인코포레이티드 포스파플라틴 액제 제형
CN110381952B (zh) 2017-01-06 2023-10-20 弗斯普拉廷治疗有限公司 作为治疗剂用于治疗骨癌或血癌的磷铂化合物
JP7381083B2 (ja) * 2017-09-08 2023-11-15 フォスプラティン テラピューティクス インコーポレイテッド 免疫調節剤としてのホスファプラチン化合物およびその治療的使用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234500A (en) 1979-03-07 1980-11-18 Engelhard Minerals & Chemicals Corporation Ethylenediamine platinum(II) and 1,2-diamino-cyclohexane platinum(II) pyrophosphate complexes
US4291027A (en) 1979-03-07 1981-09-22 Engelhard Minerals & Chemicals Corp. Method for treating tumors with ethylenediamine platinum (II) and 1,2-diaminocyclohexane-platinum (II) pyrophosphate complexes
CA2017739A1 (en) * 1989-07-18 1991-01-18 Engelhard Corporation Cis-diamineplatinum complexes with methanediphosphonate and substituted methanediphosphonate ligands as antitumor agents
WO2005000858A2 (en) * 2003-06-27 2005-01-06 Akira Odani Bisphosphonate complexes
WO2009008345A1 (ja) * 2007-07-06 2009-01-15 Tmrc Co., Ltd. 金属錯体化合物、これを有効成分とする癌治療剤組成物および該金属錯体化合物用の中間体
PL2173337T3 (pl) 2007-08-06 2014-11-28 Univ Ohio Fosfaplatyny i ich zastosowanie w leczeniu raków opornych na cisplatynę i karboplatynę

Also Published As

Publication number Publication date
JP5385274B2 (ja) 2014-01-08
US8034964B2 (en) 2011-10-11
CY1115504T1 (el) 2017-01-04
PL2173337T3 (pl) 2014-11-28
US20100233293A1 (en) 2010-09-16
JP2010535803A (ja) 2010-11-25
CN101801369B (zh) 2012-09-19
JP5647300B2 (ja) 2014-12-24
CN101801369A (zh) 2010-08-11
EP2173337A2 (en) 2010-04-14
US7700649B2 (en) 2010-04-20
WO2009021082A3 (en) 2009-04-23
WO2009021081A3 (en) 2009-05-07
EP2668949A1 (en) 2013-12-04
WO2009021081A2 (en) 2009-02-12
US20090042838A1 (en) 2009-02-12
US8445710B2 (en) 2013-05-21
ES2495743T3 (es) 2014-09-17
EP2173337A4 (en) 2010-10-27
HK1143551A1 (en) 2011-01-07
US20130237503A1 (en) 2013-09-12
US20110313182A1 (en) 2011-12-22
HRP20140808T1 (hr) 2014-10-24
JP2013227218A (ja) 2013-11-07
WO2009021082A2 (en) 2009-02-12
EP2173337B1 (en) 2014-07-30
US8653132B2 (en) 2014-02-18
DK2173337T3 (da) 2014-09-15
PT2173337E (pt) 2014-09-03

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