SI2173337T1 - Fosfaplatini in njihova uporaba pri zdravljenju vrst raka, odpornih proti cisplatinu in karboplatinu - Google Patents

Fosfaplatini in njihova uporaba pri zdravljenju vrst raka, odpornih proti cisplatinu in karboplatinu

Info

Publication number
SI2173337T1
SI2173337T1 SI200831280T SI200831280T SI2173337T1 SI 2173337 T1 SI2173337 T1 SI 2173337T1 SI 200831280 T SI200831280 T SI 200831280T SI 200831280 T SI200831280 T SI 200831280T SI 2173337 T1 SI2173337 T1 SI 2173337T1
Authority
SI
Slovenia
Prior art keywords
phosphaplatins
cisplantin
carboplatin
treatment
cancers resistant
Prior art date
Application number
SI200831280T
Other languages
English (en)
Slovenian (sl)
Inventor
Rathindra N. Bose
Original Assignee
Ohio University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ohio University filed Critical Ohio University
Publication of SI2173337T1 publication Critical patent/SI2173337T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A61K31/6615Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/665Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI200831280T 2007-08-06 2008-08-06 Fosfaplatini in njihova uporaba pri zdravljenju vrst raka, odpornih proti cisplatinu in karboplatinu SI2173337T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US95412607P 2007-08-06 2007-08-06
US97392607P 2007-09-20 2007-09-20
EP08797320.2A EP2173337B1 (en) 2007-08-06 2008-08-06 Phosphaplatins and their use in the treatment of cancers resistant to cisplantin and carboplatin
PCT/US2008/072398 WO2009021082A2 (en) 2007-08-06 2008-08-06 Phosphaplatins and their use in the treatment of cancers resistant to cisplantin and carboplatin

Publications (1)

Publication Number Publication Date
SI2173337T1 true SI2173337T1 (sl) 2014-10-30

Family

ID=40342030

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200831280T SI2173337T1 (sl) 2007-08-06 2008-08-06 Fosfaplatini in njihova uporaba pri zdravljenju vrst raka, odpornih proti cisplatinu in karboplatinu

Country Status (12)

Country Link
US (4) US7700649B2 (enExample)
EP (2) EP2173337B1 (enExample)
JP (2) JP5385274B2 (enExample)
CN (1) CN101801369B (enExample)
CY (1) CY1115504T1 (enExample)
DK (1) DK2173337T3 (enExample)
ES (1) ES2495743T3 (enExample)
HR (1) HRP20140808T1 (enExample)
PL (1) PL2173337T3 (enExample)
PT (1) PT2173337E (enExample)
SI (1) SI2173337T1 (enExample)
WO (2) WO2009021081A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101801369B (zh) 2007-08-06 2012-09-19 俄亥俄大学 磷铂及其在治疗顺铂和卡铂耐药性癌中的用途
PT2575802T (pt) * 2010-06-04 2016-12-27 Univ Ohio Fosfaplatinas e sua utilização para o tratamento de cancros
CA2818933A1 (en) * 2011-01-12 2012-07-19 Ohio University Phosphaplatins having anti-angiogenic, anti-metastatic, and pro-apoptotic properties and uses thereof
WO2013009511A1 (en) 2011-07-08 2013-01-17 Dow Global Technologies Llc Polyethylene blend composition suitable for blown film, method of producing the same, and films made therefrom
JP6027619B2 (ja) 2011-10-05 2016-11-16 ラシンドラ・エヌ・ボーズ ホスファプラチン系抗腫瘍剤の大規模調製のための効率的プロセス
CA2851254A1 (en) * 2011-10-05 2013-04-11 The University Of Houston System Efficient processes for large scale preparation of phophaplatins antitumor agents
AU2012325819B2 (en) 2011-10-20 2017-08-03 Nerium Biotechnology, Inc. Therapeutic combination for the treatment of cancer
EP2855496B1 (en) * 2012-05-24 2016-12-14 Phosplatin Therapeutics LLC Synthetic and purification methods for phosphaplatin compounds and uses thereof
WO2014130776A1 (en) 2013-02-22 2014-08-28 University Of Houston Phosphaplatins as neuroprotective agents
US20150231151A1 (en) * 2014-02-19 2015-08-20 University Of Houston System Compositions and methods for the treatment of neurodegenerative diseases
KR102412203B1 (ko) 2014-06-11 2022-06-23 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 백금 내성을 극복하는데 이용하기 위한 텍사피린-pt(iv) 접합체 및 조성물
WO2017116356A1 (en) 2015-12-30 2017-07-06 Atilim Universitesi Dna targeted mono and heterodinuclear complexes
KR102718532B1 (ko) * 2017-01-06 2024-10-21 프로몬토리 테라퓨틱스 인코포레이티드 뼈 또는 혈액 암의 치료를 위한 치료제로서의 포스파플라틴 화합물
JP7381083B2 (ja) * 2017-09-08 2023-11-15 フォスプラティン テラピューティクス インコーポレイテッド 免疫調節剤としてのホスファプラチン化合物およびその治療的使用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234500A (en) * 1979-03-07 1980-11-18 Engelhard Minerals & Chemicals Corporation Ethylenediamine platinum(II) and 1,2-diamino-cyclohexane platinum(II) pyrophosphate complexes
US4291027A (en) * 1979-03-07 1981-09-22 Engelhard Minerals & Chemicals Corp. Method for treating tumors with ethylenediamine platinum (II) and 1,2-diaminocyclohexane-platinum (II) pyrophosphate complexes
CA2017739A1 (en) * 1989-07-18 1991-01-18 Engelhard Corporation Cis-diamineplatinum complexes with methanediphosphonate and substituted methanediphosphonate ligands as antitumor agents
WO2005000858A2 (en) * 2003-06-27 2005-01-06 Akira Odani Bisphosphonate complexes
WO2009008345A1 (ja) * 2007-07-06 2009-01-15 Tmrc Co., Ltd. 金属錯体化合物、これを有効成分とする癌治療剤組成物および該金属錯体化合物用の中間体
CN101801369B (zh) 2007-08-06 2012-09-19 俄亥俄大学 磷铂及其在治疗顺铂和卡铂耐药性癌中的用途

Also Published As

Publication number Publication date
EP2173337A4 (en) 2010-10-27
US7700649B2 (en) 2010-04-20
JP2013227218A (ja) 2013-11-07
EP2173337A2 (en) 2010-04-14
ES2495743T3 (es) 2014-09-17
US20110313182A1 (en) 2011-12-22
US8445710B2 (en) 2013-05-21
DK2173337T3 (da) 2014-09-15
PL2173337T3 (pl) 2014-11-28
WO2009021082A3 (en) 2009-04-23
JP5647300B2 (ja) 2014-12-24
JP5385274B2 (ja) 2014-01-08
WO2009021081A3 (en) 2009-05-07
CN101801369A (zh) 2010-08-11
US20090042838A1 (en) 2009-02-12
US20130237503A1 (en) 2013-09-12
PT2173337E (pt) 2014-09-03
US8653132B2 (en) 2014-02-18
EP2173337B1 (en) 2014-07-30
CY1115504T1 (el) 2017-01-04
US8034964B2 (en) 2011-10-11
JP2010535803A (ja) 2010-11-25
WO2009021081A2 (en) 2009-02-12
CN101801369B (zh) 2012-09-19
HRP20140808T1 (hr) 2014-10-24
HK1143551A1 (en) 2011-01-07
EP2668949A1 (en) 2013-12-04
WO2009021082A2 (en) 2009-02-12
US20100233293A1 (en) 2010-09-16

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