DK2173337T3 - Phosphaplatiner og deres anvendelse i behandlingen af cancer, der er resistent over for cisplatin og carboplatin - Google Patents
Phosphaplatiner og deres anvendelse i behandlingen af cancer, der er resistent over for cisplatin og carboplatinInfo
- Publication number
- DK2173337T3 DK2173337T3 DK08797320.2T DK08797320T DK2173337T3 DK 2173337 T3 DK2173337 T3 DK 2173337T3 DK 08797320 T DK08797320 T DK 08797320T DK 2173337 T3 DK2173337 T3 DK 2173337T3
- Authority
- DK
- Denmark
- Prior art keywords
- phosphaplatins
- cisplatin
- treatment
- resistant cancers
- carboplatin resistant
- Prior art date
Links
- 229960004562 carboplatin Drugs 0.000 title 1
- 190000008236 carboplatin Chemical compound 0.000 title 1
- 229960004316 cisplatin Drugs 0.000 title 1
- DQLATGHUWYMOKM-UHFFFAOYSA-L cisplatin Chemical compound N[Pt](N)(Cl)Cl DQLATGHUWYMOKM-UHFFFAOYSA-L 0.000 title 1
- 208000016691 refractory malignant neoplasm Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
- A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95412607P | 2007-08-06 | 2007-08-06 | |
| US97392607P | 2007-09-20 | 2007-09-20 | |
| PCT/US2008/072398 WO2009021082A2 (en) | 2007-08-06 | 2008-08-06 | Phosphaplatins and their use in the treatment of cancers resistant to cisplantin and carboplatin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2173337T3 true DK2173337T3 (da) | 2014-09-15 |
Family
ID=40342030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK08797320.2T DK2173337T3 (da) | 2007-08-06 | 2008-08-06 | Phosphaplatiner og deres anvendelse i behandlingen af cancer, der er resistent over for cisplatin og carboplatin |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US7700649B2 (enExample) |
| EP (2) | EP2668949A1 (enExample) |
| JP (2) | JP5385274B2 (enExample) |
| CN (1) | CN101801369B (enExample) |
| CY (1) | CY1115504T1 (enExample) |
| DK (1) | DK2173337T3 (enExample) |
| ES (1) | ES2495743T3 (enExample) |
| HR (1) | HRP20140808T1 (enExample) |
| PL (1) | PL2173337T3 (enExample) |
| PT (1) | PT2173337E (enExample) |
| SI (1) | SI2173337T1 (enExample) |
| WO (2) | WO2009021081A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2173337T3 (pl) | 2007-08-06 | 2014-11-28 | Univ Ohio | Fosfaplatyny i ich zastosowanie w leczeniu raków opornych na cisplatynę i karboplatynę |
| JP5860872B2 (ja) * | 2010-06-04 | 2016-02-16 | オハイオ ユニバーシティー | ホスファプラチン、及び癌治療のためのそれらの使用 |
| EP2663301A1 (en) | 2011-01-12 | 2013-11-20 | Ohio University | Phosphaplatins having anti-angiogenic, anti-metastatic, and pro-apoptotic properties and uses thereof |
| MX354678B (es) | 2011-07-08 | 2018-03-15 | Dow Global Technologies Llc | Composicion de mezcla de polietileno adecuada para pelicula soplada, metodo para producir la misma y peliculas hechas a partir de la misma. |
| CA2851254A1 (en) * | 2011-10-05 | 2013-04-11 | The University Of Houston System | Efficient processes for large scale preparation of phophaplatins antitumor agents |
| MX357865B (es) | 2011-10-05 | 2018-07-25 | N Bose Rathindra | Procedimientos eficientes para preparación a gran escala de agentes antitumorales de fosfaplatinos. |
| EP2768498B1 (en) | 2011-10-20 | 2020-03-04 | Nerium Biotechnology, Inc. | Therapeutic combination for the treatment of cancer |
| PT3202769T (pt) | 2012-05-24 | 2019-10-31 | Phosplatin Therapeutics Llc | Processos de síntese e de purificação para compostos de fosfaplatina e aplicações dos mesmos |
| US9333211B2 (en) * | 2013-02-22 | 2016-05-10 | University Of Houston System | Phosphaplatin mediated modulation of pigment epithelial derived factor and uses thereof |
| US20150231151A1 (en) * | 2014-02-19 | 2015-08-20 | University Of Houston System | Compositions and methods for the treatment of neurodegenerative diseases |
| SG11201610306RA (en) | 2014-06-11 | 2017-01-27 | Univ Texas | Texaphyrin-pt(iv) conjugates and compositions for use in overcoming platinum resistance |
| EP3397642A1 (en) | 2015-12-30 | 2018-11-07 | Atilim Universitesi | Dna targeted mono and heterodinuclear complexes |
| KR102419247B1 (ko) | 2016-04-06 | 2022-07-11 | 포스플라틴 테라퓨틱스 인코포레이티드 | 포스파플라틴 액제 제형 |
| CN110381952B (zh) | 2017-01-06 | 2023-10-20 | 弗斯普拉廷治疗有限公司 | 作为治疗剂用于治疗骨癌或血癌的磷铂化合物 |
| JP7381083B2 (ja) * | 2017-09-08 | 2023-11-15 | フォスプラティン テラピューティクス インコーポレイテッド | 免疫調節剤としてのホスファプラチン化合物およびその治療的使用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4234500A (en) | 1979-03-07 | 1980-11-18 | Engelhard Minerals & Chemicals Corporation | Ethylenediamine platinum(II) and 1,2-diamino-cyclohexane platinum(II) pyrophosphate complexes |
| US4291027A (en) | 1979-03-07 | 1981-09-22 | Engelhard Minerals & Chemicals Corp. | Method for treating tumors with ethylenediamine platinum (II) and 1,2-diaminocyclohexane-platinum (II) pyrophosphate complexes |
| CA2017739A1 (en) * | 1989-07-18 | 1991-01-18 | Engelhard Corporation | Cis-diamineplatinum complexes with methanediphosphonate and substituted methanediphosphonate ligands as antitumor agents |
| WO2005000858A2 (en) * | 2003-06-27 | 2005-01-06 | Akira Odani | Bisphosphonate complexes |
| WO2009008345A1 (ja) * | 2007-07-06 | 2009-01-15 | Tmrc Co., Ltd. | 金属錯体化合物、これを有効成分とする癌治療剤組成物および該金属錯体化合物用の中間体 |
| PL2173337T3 (pl) | 2007-08-06 | 2014-11-28 | Univ Ohio | Fosfaplatyny i ich zastosowanie w leczeniu raków opornych na cisplatynę i karboplatynę |
-
2008
- 2008-08-06 PL PL08797320T patent/PL2173337T3/pl unknown
- 2008-08-06 WO PCT/US2008/072397 patent/WO2009021081A2/en not_active Ceased
- 2008-08-06 HR HRP20140808AT patent/HRP20140808T1/hr unknown
- 2008-08-06 US US12/187,376 patent/US7700649B2/en active Active
- 2008-08-06 ES ES08797320.2T patent/ES2495743T3/es active Active
- 2008-08-06 CN CN2008801015774A patent/CN101801369B/zh active Active
- 2008-08-06 EP EP13182512.7A patent/EP2668949A1/en not_active Withdrawn
- 2008-08-06 WO PCT/US2008/072398 patent/WO2009021082A2/en not_active Ceased
- 2008-08-06 EP EP08797320.2A patent/EP2173337B1/en active Active
- 2008-08-06 PT PT87973202T patent/PT2173337E/pt unknown
- 2008-08-06 JP JP2010520294A patent/JP5385274B2/ja active Active
- 2008-08-06 SI SI200831280T patent/SI2173337T1/sl unknown
- 2008-08-06 DK DK08797320.2T patent/DK2173337T3/da active
-
2010
- 2010-03-11 US US12/722,189 patent/US8034964B2/en active Active
-
2011
- 2011-08-30 US US13/221,458 patent/US8445710B2/en active Active
-
2013
- 2013-03-15 US US13/842,885 patent/US8653132B2/en active Active
- 2013-06-07 JP JP2013120309A patent/JP5647300B2/ja active Active
-
2014
- 2014-08-27 CY CY20141100686T patent/CY1115504T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP5385274B2 (ja) | 2014-01-08 |
| US8034964B2 (en) | 2011-10-11 |
| CY1115504T1 (el) | 2017-01-04 |
| PL2173337T3 (pl) | 2014-11-28 |
| US20100233293A1 (en) | 2010-09-16 |
| JP2010535803A (ja) | 2010-11-25 |
| SI2173337T1 (sl) | 2014-10-30 |
| CN101801369B (zh) | 2012-09-19 |
| JP5647300B2 (ja) | 2014-12-24 |
| CN101801369A (zh) | 2010-08-11 |
| EP2173337A2 (en) | 2010-04-14 |
| US7700649B2 (en) | 2010-04-20 |
| WO2009021082A3 (en) | 2009-04-23 |
| WO2009021081A3 (en) | 2009-05-07 |
| EP2668949A1 (en) | 2013-12-04 |
| WO2009021081A2 (en) | 2009-02-12 |
| US20090042838A1 (en) | 2009-02-12 |
| US8445710B2 (en) | 2013-05-21 |
| ES2495743T3 (es) | 2014-09-17 |
| EP2173337A4 (en) | 2010-10-27 |
| HK1143551A1 (en) | 2011-01-07 |
| US20130237503A1 (en) | 2013-09-12 |
| US20110313182A1 (en) | 2011-12-22 |
| HRP20140808T1 (hr) | 2014-10-24 |
| JP2013227218A (ja) | 2013-11-07 |
| WO2009021082A2 (en) | 2009-02-12 |
| EP2173337B1 (en) | 2014-07-30 |
| US8653132B2 (en) | 2014-02-18 |
| PT2173337E (pt) | 2014-09-03 |
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