PT2173337E - Fosfoplatinas e a sua utilização no tratamento de cancros resistentes à cisplantina e carboplatina - Google Patents

Fosfoplatinas e a sua utilização no tratamento de cancros resistentes à cisplantina e carboplatina Download PDF

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Publication number
PT2173337E
PT2173337E PT87973202T PT08797320T PT2173337E PT 2173337 E PT2173337 E PT 2173337E PT 87973202 T PT87973202 T PT 87973202T PT 08797320 T PT08797320 T PT 08797320T PT 2173337 E PT2173337 E PT 2173337E
Authority
PT
Portugal
Prior art keywords
phosphaplatins
cisplantin
carboplatin
treatment
cancers resistant
Prior art date
Application number
PT87973202T
Other languages
English (en)
Inventor
Rathindra N Bose
Original Assignee
Univ Ohio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Ohio filed Critical Univ Ohio
Publication of PT2173337E publication Critical patent/PT2173337E/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT87973202T 2007-08-06 2008-08-06 Fosfoplatinas e a sua utilização no tratamento de cancros resistentes à cisplantina e carboplatina PT2173337E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95412607P 2007-08-06 2007-08-06
US97392607P 2007-09-20 2007-09-20

Publications (1)

Publication Number Publication Date
PT2173337E true PT2173337E (pt) 2014-09-03

Family

ID=40342030

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87973202T PT2173337E (pt) 2007-08-06 2008-08-06 Fosfoplatinas e a sua utilização no tratamento de cancros resistentes à cisplantina e carboplatina

Country Status (13)

Country Link
US (4) US7700649B2 (pt)
EP (2) EP2668949A1 (pt)
JP (2) JP5385274B2 (pt)
CN (1) CN101801369B (pt)
CY (1) CY1115504T1 (pt)
DK (1) DK2173337T3 (pt)
ES (1) ES2495743T3 (pt)
HK (1) HK1143551A1 (pt)
HR (1) HRP20140808T1 (pt)
PL (1) PL2173337T3 (pt)
PT (1) PT2173337E (pt)
SI (1) SI2173337T1 (pt)
WO (2) WO2009021082A2 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2173337T3 (pl) 2007-08-06 2014-11-28 Univ Ohio Fosfaplatyny i ich zastosowanie w leczeniu raków opornych na cisplatynę i karboplatynę
CN108409795A (zh) * 2010-06-04 2018-08-17 俄亥俄大学 磷铂及其在治疗癌症中的用途
US20130236568A1 (en) * 2011-01-12 2013-09-12 Ohio University Phosphaplatins having anti-angiogenic, anti-metastatic, and pro-apoptotic properties and uses thereof
KR101901477B1 (ko) 2011-07-08 2018-09-21 다우 글로벌 테크놀로지스 엘엘씨 블로운 필름에 적합한 폴리에틸렌 배합 조성물, 그 제조 방법, 및 그로부터 제조된 필름
CN104010508B (zh) * 2011-10-05 2017-03-15 理辛德拉·N·博斯 用于大规模制备磷铂类抗肿瘤剂的高效方法
US9012669B2 (en) 2011-10-05 2015-04-21 The University Of Houston System Efficient processes for large scale preparation of phosphaplatins antitumor agents
RU2017136415A (ru) 2011-10-20 2019-02-08 Нериум Байотекнолоджи, Инк. Терапевтическая комбинация для лечения рака
PT3202769T (pt) * 2012-05-24 2019-10-31 Phosplatin Therapeutics Llc Processos de síntese e de purificação para compostos de fosfaplatina e aplicações dos mesmos
JP6382231B2 (ja) * 2013-02-22 2018-08-29 ユニバーシティ オブ ヒューストンＵｎｉｖｅｒｓｉｔｙ Ｏｆ Ｈｏｕｓｔｏｎ 神経保護剤としてのホスファプラチン
US20150231151A1 (en) * 2014-02-19 2015-08-20 University Of Houston System Compositions and methods for the treatment of neurodegenerative diseases
BR112016029024A8 (pt) 2014-06-11 2021-07-20 Univ Texas composto, composição farmacêutica e uso
WO2017116356A1 (en) 2015-12-30 2017-07-06 Atilim Universitesi Dna targeted mono and heterodinuclear complexes
KR20190103258A (ko) * 2017-01-06 2019-09-04 포스플라틴 테라퓨틱스 엘엘씨 뼈 또는 혈액 암의 치료를 위한 치료제로서의 포스파플라틴 화합물
AU2018327339B2 (en) * 2017-09-08 2023-10-12 Promontory Therapeutics Inc. Phosphaplatin compounds as immuno-modulatory agents and therapeutic uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4291027A (en) 1979-03-07 1981-09-22 Engelhard Minerals & Chemicals Corp. Method for treating tumors with ethylenediamine platinum (II) and 1,2-diaminocyclohexane-platinum (II) pyrophosphate complexes
US4234500A (en) * 1979-03-07 1980-11-18 Engelhard Minerals & Chemicals Corporation Ethylenediamine platinum(II) and 1,2-diamino-cyclohexane platinum(II) pyrophosphate complexes
CA2017739A1 (en) * 1989-07-18 1991-01-18 Leslie S. Hollis Cis-diamineplatinum complexes with methanediphosphonate and substituted methanediphosphonate ligands as antitumor agents
CA2530279A1 (en) * 2003-06-27 2005-01-06 Akira Odani Bisphosphonate complexes
JPWO2009008345A1 (ja) * 2007-07-06 2010-09-09 久雄 浴本 金属錯体化合物、これを有効成分とする癌治療剤組成物および該金属錯体化合物用の中間体
PL2173337T3 (pl) * 2007-08-06 2014-11-28 Univ Ohio Fosfaplatyny i ich zastosowanie w leczeniu raków opornych na cisplatynę i karboplatynę

Also Published As

Publication number Publication date
ES2495743T3 (es) 2014-09-17
US20110313182A1 (en) 2011-12-22
EP2173337A4 (en) 2010-10-27
US20100233293A1 (en) 2010-09-16
JP2013227218A (ja) 2013-11-07
WO2009021082A3 (en) 2009-04-23
CN101801369B (zh) 2012-09-19
JP5647300B2 (ja) 2014-12-24
SI2173337T1 (sl) 2014-10-30
EP2173337B1 (en) 2014-07-30
US8653132B2 (en) 2014-02-18
US20130237503A1 (en) 2013-09-12
DK2173337T3 (da) 2014-09-15
EP2668949A1 (en) 2013-12-04
US8445710B2 (en) 2013-05-21
WO2009021081A3 (en) 2009-05-07
HRP20140808T1 (hr) 2014-10-24
JP2010535803A (ja) 2010-11-25
US8034964B2 (en) 2011-10-11
CN101801369A (zh) 2010-08-11
JP5385274B2 (ja) 2014-01-08
EP2173337A2 (en) 2010-04-14
US20090042838A1 (en) 2009-02-12
WO2009021081A2 (en) 2009-02-12
HK1143551A1 (en) 2011-01-07
US7700649B2 (en) 2010-04-20
WO2009021082A2 (en) 2009-02-12
CY1115504T1 (el) 2017-01-04
PL2173337T3 (pl) 2014-11-28

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