DK2235002T3 - 4-pyridinonforbindelser og anvendelse heraf til behandling af cancer - Google Patents

4-pyridinonforbindelser og anvendelse heraf til behandling af cancer

Info

Publication number
DK2235002T3
DK2235002T3 DK09704457.2T DK09704457T DK2235002T3 DK 2235002 T3 DK2235002 T3 DK 2235002T3 DK 09704457 T DK09704457 T DK 09704457T DK 2235002 T3 DK2235002 T3 DK 2235002T3
Authority
DK
Denmark
Prior art keywords
cancer
treatment
pyridinone compounds
pyridinone
compounds
Prior art date
Application number
DK09704457.2T
Other languages
English (en)
Inventor
Robert M Borzilleri
Zhen-Wei Cai
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DK2235002T3 publication Critical patent/DK2235002T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
DK09704457.2T 2008-01-23 2009-01-22 4-pyridinonforbindelser og anvendelse heraf til behandling af cancer DK2235002T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2284808P 2008-01-23 2008-01-23
PCT/US2009/031649 WO2009094417A1 (en) 2008-01-23 2009-01-22 4-pyridinone compounds and their use for cancer

Publications (1)

Publication Number Publication Date
DK2235002T3 true DK2235002T3 (da) 2013-03-11

Family

ID=40637826

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09704457.2T DK2235002T3 (da) 2008-01-23 2009-01-22 4-pyridinonforbindelser og anvendelse heraf til behandling af cancer

Country Status (22)

Country Link
US (2) US8124768B2 (da)
EP (1) EP2235002B1 (da)
JP (1) JP5314050B2 (da)
KR (1) KR101596527B1 (da)
CN (1) CN101977906B (da)
AU (1) AU2009206440B2 (da)
BR (1) BRPI0906444B8 (da)
CA (1) CA2713111C (da)
CO (1) CO6230986A2 (da)
CY (1) CY1114140T1 (da)
DK (1) DK2235002T3 (da)
EA (1) EA017736B1 (da)
ES (1) ES2398335T3 (da)
HK (1) HK1143157A1 (da)
HR (1) HRP20130040T1 (da)
IL (1) IL207212A (da)
NZ (1) NZ586630A (da)
PL (1) PL2235002T3 (da)
PT (1) PT2235002E (da)
SI (1) SI2235002T1 (da)
WO (1) WO2009094417A1 (da)
ZA (1) ZA201005248B (da)

Families Citing this family (13)

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US8293897B2 (en) 2008-10-14 2012-10-23 Ning Xi Compounds comprising a spiro-ring and methods of use
CA2752421C (en) 2009-03-21 2013-08-06 Ning Xi Amino ester derivatives, salts thereof and methods of use
WO2011139891A1 (en) * 2010-04-29 2011-11-10 Deciphera Pharmaceuticals, Llc Pyridone amides and analogs exhibiting anti-cancer and anti-proliferative activites
RU2477723C2 (ru) 2011-06-16 2013-03-20 Общество С Ограниченной Ответственностью "Фьюжн Фарма" Ингибиторы протеинкиназ (варианты), их применение для лечения онкологических заболеваний и фармацевтическая композиция на их основе
PL2810937T3 (pl) 2012-01-31 2017-07-31 Daiichi Sankyo Company, Limited Pochodna pirydonu
AU2013296897B2 (en) 2012-07-28 2015-09-17 Beijing Findcure Biosciences Ltd. Substituted pyrazolone compounds and methods of use
US8975282B2 (en) 2012-07-28 2015-03-10 Sunshine Lake Pharma Co., Ltd. Substituted pyrazolone compounds and methods of use
US20140057920A1 (en) 2012-08-23 2014-02-27 Boehringer Ingelheim International Gmbh Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity
US20140057926A1 (en) * 2012-08-23 2014-02-27 Boehringer Ingelheim International Gmbh Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity
US9102624B2 (en) 2012-08-23 2015-08-11 Boehringer Ingelheim International Gmbh Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity
TWI723572B (zh) 2014-07-07 2021-04-01 日商第一三共股份有限公司 具有四氫吡喃基甲基之吡啶酮衍生物及其用途
CN105153026B (zh) * 2015-08-21 2018-02-02 江西科技师范大学 含联芳基酰胺结构的索拉非尼衍生物及其制备方法和应用
WO2024067783A1 (zh) * 2022-09-28 2024-04-04 上海济煜医药科技有限公司 含磷类化合物及其制备方法和医药应用

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EP0430885A3 (en) 1989-12-01 1991-11-06 Ciba-Geigy Ag Anthelmintical compounds
WO1997017329A1 (fr) 1995-11-07 1997-05-15 Kirin Beer Kabushiki Kaisha Derives de quinoline et derives de quinazoline inhibant l'autophosphorylation d'un recepteur de facteur de croissance originaire de plaquettes, et compositions pharmaceutiques les contenant
US6429213B1 (en) 1998-06-17 2002-08-06 Bristol Myers Squibb Pharma Co Cyclic hydroxamic acids as metalloproteinase inhibitors
KR100743262B1 (ko) 1999-07-20 2007-07-27 다우 아그로사이언시즈 엘엘씨 살균성 헤테로고리 방향족 아미드 및 그 조성물, 사용 및제조방법
US6355660B1 (en) 1999-07-20 2002-03-12 Dow Agrosciences Llc Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
RU2002110461A (ru) 1999-09-21 2004-03-10 Астразенека Аб (Se) Производные хиназолина и их применение в качестве фармацевтических веществ
AU4398801A (en) * 2000-03-22 2001-10-03 Banyu Pharmaceutical Co., Ltd. Sulfur substituted aryldifluoromethylphosphonic acids as ptp-1b inhibitors
FR2812633A1 (fr) 2000-08-04 2002-02-08 Aventis Cropscience Sa Derives de phenyl(thio)urees et phenyl(thio)carbamates fongicides
SE0102384D0 (sv) 2001-07-03 2001-07-03 Pharmacia Ab New compounds
AU2002344567A1 (en) 2001-11-28 2003-06-10 Daiso Co., Ltd. Heterocyclic amide compounds as apolipoprotein b inhibitors
SE0302487D0 (sv) 2003-09-18 2003-09-18 Astrazeneca Ab Novel compounds
JP4829506B2 (ja) 2004-02-17 2011-12-07 石原産業株式会社 チオアミド系化合物又はその塩、並びにそれらを含有するサイトカイン産生抑制剤
US7459562B2 (en) * 2004-04-23 2008-12-02 Bristol-Myers Squibb Company Monocyclic heterocycles as kinase inhibitors
AU2005245386B2 (en) 2004-05-07 2008-11-27 Amgen Inc. Nitrogenated heterocyclic derivatives as protein kinase modulators and use for the treatment of angiogenesis and cancer
US7432373B2 (en) 2004-06-28 2008-10-07 Bristol-Meyers Squibb Company Processes and intermediates useful for preparing fused heterocyclic kinase inhibitors
US20050288290A1 (en) 2004-06-28 2005-12-29 Borzilleri Robert M Fused heterocyclic kinase inhibitors
US7439246B2 (en) 2004-06-28 2008-10-21 Bristol-Myers Squibb Company Fused heterocyclic kinase inhibitors
JO2787B1 (en) 2005-04-27 2014-03-15 امجين إنك, Alternative amide derivatives and methods of use
US7732613B2 (en) 2005-09-14 2010-06-08 Bristol-Myers Squibb Company Met kinase inhibitors
WO2007035428A1 (en) 2005-09-15 2007-03-29 Bristol-Myers Squibb Company Met kinase inhibitors
US7348325B2 (en) 2005-11-30 2008-03-25 Bristol-Myers Squibb Company Pyrrolotriazine kinase inhibitors
CN101977905B (zh) 2008-01-23 2014-07-02 百时美施贵宝公司 4-吡啶酮化合物及其对于癌症的用途

Also Published As

Publication number Publication date
NZ586630A (en) 2011-12-22
CO6230986A2 (es) 2010-12-20
PL2235002T3 (pl) 2013-04-30
EP2235002A1 (en) 2010-10-06
ES2398335T3 (es) 2013-03-15
BRPI0906444A8 (pt) 2020-02-27
KR101596527B1 (ko) 2016-02-22
BRPI0906444B1 (pt) 2021-03-16
HK1143157A1 (en) 2010-12-24
WO2009094417A1 (en) 2009-07-30
EA017736B1 (ru) 2013-02-28
ZA201005248B (en) 2011-09-28
JP5314050B2 (ja) 2013-10-16
US20110034416A1 (en) 2011-02-10
CN101977906A (zh) 2011-02-16
HRP20130040T1 (hr) 2013-02-28
KR20100103636A (ko) 2010-09-27
SI2235002T1 (sl) 2013-06-28
AU2009206440B2 (en) 2013-08-15
EA201001196A1 (ru) 2011-02-28
CA2713111A1 (en) 2009-07-30
US20120114643A1 (en) 2012-05-10
CN101977906B (zh) 2014-11-05
US8124768B2 (en) 2012-02-28
EP2235002B1 (en) 2012-11-21
US8258118B2 (en) 2012-09-04
CA2713111C (en) 2015-06-30
BRPI0906444A2 (pt) 2015-07-14
PT2235002E (pt) 2013-01-30
CY1114140T1 (el) 2016-07-27
IL207212A (en) 2015-01-29
IL207212A0 (en) 2010-12-30
JP2011510087A (ja) 2011-03-31
BRPI0906444B8 (pt) 2021-05-25
AU2009206440A1 (en) 2009-07-30

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