DK2235002T3 - 4-pyridinonforbindelser og anvendelse heraf til behandling af cancer - Google Patents
4-pyridinonforbindelser og anvendelse heraf til behandling af cancerInfo
- Publication number
- DK2235002T3 DK2235002T3 DK09704457.2T DK09704457T DK2235002T3 DK 2235002 T3 DK2235002 T3 DK 2235002T3 DK 09704457 T DK09704457 T DK 09704457T DK 2235002 T3 DK2235002 T3 DK 2235002T3
- Authority
- DK
- Denmark
- Prior art keywords
- cancer
- treatment
- pyridinone compounds
- pyridinone
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2284808P | 2008-01-23 | 2008-01-23 | |
PCT/US2009/031649 WO2009094417A1 (en) | 2008-01-23 | 2009-01-22 | 4-pyridinone compounds and their use for cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2235002T3 true DK2235002T3 (da) | 2013-03-11 |
Family
ID=40637826
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK09704457.2T DK2235002T3 (da) | 2008-01-23 | 2009-01-22 | 4-pyridinonforbindelser og anvendelse heraf til behandling af cancer |
Country Status (22)
Country | Link |
---|---|
US (2) | US8124768B2 (da) |
EP (1) | EP2235002B1 (da) |
JP (1) | JP5314050B2 (da) |
KR (1) | KR101596527B1 (da) |
CN (1) | CN101977906B (da) |
AU (1) | AU2009206440B2 (da) |
BR (1) | BRPI0906444B8 (da) |
CA (1) | CA2713111C (da) |
CO (1) | CO6230986A2 (da) |
CY (1) | CY1114140T1 (da) |
DK (1) | DK2235002T3 (da) |
EA (1) | EA017736B1 (da) |
ES (1) | ES2398335T3 (da) |
HK (1) | HK1143157A1 (da) |
HR (1) | HRP20130040T1 (da) |
IL (1) | IL207212A (da) |
NZ (1) | NZ586630A (da) |
PL (1) | PL2235002T3 (da) |
PT (1) | PT2235002E (da) |
SI (1) | SI2235002T1 (da) |
WO (1) | WO2009094417A1 (da) |
ZA (1) | ZA201005248B (da) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8293897B2 (en) | 2008-10-14 | 2012-10-23 | Ning Xi | Compounds comprising a spiro-ring and methods of use |
CA2752421C (en) | 2009-03-21 | 2013-08-06 | Ning Xi | Amino ester derivatives, salts thereof and methods of use |
WO2011139891A1 (en) * | 2010-04-29 | 2011-11-10 | Deciphera Pharmaceuticals, Llc | Pyridone amides and analogs exhibiting anti-cancer and anti-proliferative activites |
RU2477723C2 (ru) | 2011-06-16 | 2013-03-20 | Общество С Ограниченной Ответственностью "Фьюжн Фарма" | Ингибиторы протеинкиназ (варианты), их применение для лечения онкологических заболеваний и фармацевтическая композиция на их основе |
PL2810937T3 (pl) | 2012-01-31 | 2017-07-31 | Daiichi Sankyo Company, Limited | Pochodna pirydonu |
AU2013296897B2 (en) | 2012-07-28 | 2015-09-17 | Beijing Findcure Biosciences Ltd. | Substituted pyrazolone compounds and methods of use |
US8975282B2 (en) | 2012-07-28 | 2015-03-10 | Sunshine Lake Pharma Co., Ltd. | Substituted pyrazolone compounds and methods of use |
US20140057920A1 (en) | 2012-08-23 | 2014-02-27 | Boehringer Ingelheim International Gmbh | Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity |
US20140057926A1 (en) * | 2012-08-23 | 2014-02-27 | Boehringer Ingelheim International Gmbh | Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity |
US9102624B2 (en) | 2012-08-23 | 2015-08-11 | Boehringer Ingelheim International Gmbh | Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity |
TWI723572B (zh) | 2014-07-07 | 2021-04-01 | 日商第一三共股份有限公司 | 具有四氫吡喃基甲基之吡啶酮衍生物及其用途 |
CN105153026B (zh) * | 2015-08-21 | 2018-02-02 | 江西科技师范大学 | 含联芳基酰胺结构的索拉非尼衍生物及其制备方法和应用 |
WO2024067783A1 (zh) * | 2022-09-28 | 2024-04-04 | 上海济煜医药科技有限公司 | 含磷类化合物及其制备方法和医药应用 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0430885A3 (en) | 1989-12-01 | 1991-11-06 | Ciba-Geigy Ag | Anthelmintical compounds |
WO1997017329A1 (fr) | 1995-11-07 | 1997-05-15 | Kirin Beer Kabushiki Kaisha | Derives de quinoline et derives de quinazoline inhibant l'autophosphorylation d'un recepteur de facteur de croissance originaire de plaquettes, et compositions pharmaceutiques les contenant |
US6429213B1 (en) | 1998-06-17 | 2002-08-06 | Bristol Myers Squibb Pharma Co | Cyclic hydroxamic acids as metalloproteinase inhibitors |
KR100743262B1 (ko) | 1999-07-20 | 2007-07-27 | 다우 아그로사이언시즈 엘엘씨 | 살균성 헤테로고리 방향족 아미드 및 그 조성물, 사용 및제조방법 |
US6355660B1 (en) | 1999-07-20 | 2002-03-12 | Dow Agrosciences Llc | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation |
RU2002110461A (ru) | 1999-09-21 | 2004-03-10 | Астразенека Аб (Se) | Производные хиназолина и их применение в качестве фармацевтических веществ |
AU4398801A (en) * | 2000-03-22 | 2001-10-03 | Banyu Pharmaceutical Co., Ltd. | Sulfur substituted aryldifluoromethylphosphonic acids as ptp-1b inhibitors |
FR2812633A1 (fr) | 2000-08-04 | 2002-02-08 | Aventis Cropscience Sa | Derives de phenyl(thio)urees et phenyl(thio)carbamates fongicides |
SE0102384D0 (sv) | 2001-07-03 | 2001-07-03 | Pharmacia Ab | New compounds |
AU2002344567A1 (en) | 2001-11-28 | 2003-06-10 | Daiso Co., Ltd. | Heterocyclic amide compounds as apolipoprotein b inhibitors |
SE0302487D0 (sv) | 2003-09-18 | 2003-09-18 | Astrazeneca Ab | Novel compounds |
JP4829506B2 (ja) | 2004-02-17 | 2011-12-07 | 石原産業株式会社 | チオアミド系化合物又はその塩、並びにそれらを含有するサイトカイン産生抑制剤 |
US7459562B2 (en) * | 2004-04-23 | 2008-12-02 | Bristol-Myers Squibb Company | Monocyclic heterocycles as kinase inhibitors |
AU2005245386B2 (en) | 2004-05-07 | 2008-11-27 | Amgen Inc. | Nitrogenated heterocyclic derivatives as protein kinase modulators and use for the treatment of angiogenesis and cancer |
US7432373B2 (en) | 2004-06-28 | 2008-10-07 | Bristol-Meyers Squibb Company | Processes and intermediates useful for preparing fused heterocyclic kinase inhibitors |
US20050288290A1 (en) | 2004-06-28 | 2005-12-29 | Borzilleri Robert M | Fused heterocyclic kinase inhibitors |
US7439246B2 (en) | 2004-06-28 | 2008-10-21 | Bristol-Myers Squibb Company | Fused heterocyclic kinase inhibitors |
JO2787B1 (en) | 2005-04-27 | 2014-03-15 | امجين إنك, | Alternative amide derivatives and methods of use |
US7732613B2 (en) | 2005-09-14 | 2010-06-08 | Bristol-Myers Squibb Company | Met kinase inhibitors |
WO2007035428A1 (en) | 2005-09-15 | 2007-03-29 | Bristol-Myers Squibb Company | Met kinase inhibitors |
US7348325B2 (en) | 2005-11-30 | 2008-03-25 | Bristol-Myers Squibb Company | Pyrrolotriazine kinase inhibitors |
CN101977905B (zh) | 2008-01-23 | 2014-07-02 | 百时美施贵宝公司 | 4-吡啶酮化合物及其对于癌症的用途 |
-
2009
- 2009-01-22 PT PT97044572T patent/PT2235002E/pt unknown
- 2009-01-22 DK DK09704457.2T patent/DK2235002T3/da active
- 2009-01-22 CN CN200980110414.7A patent/CN101977906B/zh active Active
- 2009-01-22 AU AU2009206440A patent/AU2009206440B2/en active Active
- 2009-01-22 CA CA2713111A patent/CA2713111C/en active Active
- 2009-01-22 PL PL09704457T patent/PL2235002T3/pl unknown
- 2009-01-22 EP EP09704457A patent/EP2235002B1/en active Active
- 2009-01-22 KR KR1020107016439A patent/KR101596527B1/ko active IP Right Grant
- 2009-01-22 BR BRPI0906444A patent/BRPI0906444B8/pt active IP Right Grant
- 2009-01-22 SI SI200930516T patent/SI2235002T1/sl unknown
- 2009-01-22 NZ NZ586630A patent/NZ586630A/en unknown
- 2009-01-22 JP JP2010544403A patent/JP5314050B2/ja active Active
- 2009-01-22 US US12/863,697 patent/US8124768B2/en active Active
- 2009-01-22 ES ES09704457T patent/ES2398335T3/es active Active
- 2009-01-22 WO PCT/US2009/031649 patent/WO2009094417A1/en active Application Filing
- 2009-01-22 EA EA201001196A patent/EA017736B1/ru not_active IP Right Cessation
-
2010
- 2010-07-13 CO CO10085288A patent/CO6230986A2/es active IP Right Grant
- 2010-07-22 ZA ZA2010/05248A patent/ZA201005248B/en unknown
- 2010-07-25 IL IL207212A patent/IL207212A/en active IP Right Grant
- 2010-10-13 HK HK10109674.2A patent/HK1143157A1/en unknown
-
2012
- 2012-01-12 US US13/349,173 patent/US8258118B2/en active Active
-
2013
- 2013-01-17 HR HRP20130040AT patent/HRP20130040T1/hr unknown
- 2013-02-08 CY CY20131100116T patent/CY1114140T1/el unknown
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