PL2235002T3 - Związki 4-pirydynonu i ich zastosowanie w raku - Google Patents

Związki 4-pirydynonu i ich zastosowanie w raku

Info

Publication number
PL2235002T3
PL2235002T3 PL09704457T PL09704457T PL2235002T3 PL 2235002 T3 PL2235002 T3 PL 2235002T3 PL 09704457 T PL09704457 T PL 09704457T PL 09704457 T PL09704457 T PL 09704457T PL 2235002 T3 PL2235002 T3 PL 2235002T3
Authority
PL
Poland
Prior art keywords
cancer
pyridinone compounds
pyridinone
compounds
Prior art date
Application number
PL09704457T
Other languages
English (en)
Inventor
Robert M Borzilleri
Zhen-Wei Cai
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of PL2235002T3 publication Critical patent/PL2235002T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL09704457T 2008-01-23 2009-01-22 Związki 4-pirydynonu i ich zastosowanie w raku PL2235002T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2284808P 2008-01-23 2008-01-23
EP09704457A EP2235002B1 (en) 2008-01-23 2009-01-22 4-pyridinone compounds and their use for cancer
PCT/US2009/031649 WO2009094417A1 (en) 2008-01-23 2009-01-22 4-pyridinone compounds and their use for cancer

Publications (1)

Publication Number Publication Date
PL2235002T3 true PL2235002T3 (pl) 2013-04-30

Family

ID=40637826

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09704457T PL2235002T3 (pl) 2008-01-23 2009-01-22 Związki 4-pirydynonu i ich zastosowanie w raku

Country Status (22)

Country Link
US (2) US8124768B2 (pl)
EP (1) EP2235002B1 (pl)
JP (1) JP5314050B2 (pl)
KR (1) KR101596527B1 (pl)
CN (1) CN101977906B (pl)
AU (1) AU2009206440B2 (pl)
BR (1) BRPI0906444B8 (pl)
CA (1) CA2713111C (pl)
CO (1) CO6230986A2 (pl)
CY (1) CY1114140T1 (pl)
DK (1) DK2235002T3 (pl)
EA (1) EA017736B1 (pl)
ES (1) ES2398335T3 (pl)
HK (1) HK1143157A1 (pl)
HR (1) HRP20130040T1 (pl)
IL (1) IL207212A (pl)
NZ (1) NZ586630A (pl)
PL (1) PL2235002T3 (pl)
PT (1) PT2235002E (pl)
SI (1) SI2235002T1 (pl)
WO (1) WO2009094417A1 (pl)
ZA (1) ZA201005248B (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009303602B2 (en) 2008-10-14 2012-06-14 Sunshine Lake Pharma Co., Ltd. Compounds and methods of use
EP2408300B1 (en) 2009-03-21 2016-05-11 Sunshine Lake Pharma Co., Ltd. Amino ester derivatives, salts thereof and methods of use
EP2563773A1 (en) 2010-04-29 2013-03-06 Deciphera Pharmaceuticals, LLC Pyridone amides and analogs exhibiting anti-cancer and anti-proliferative activites
RU2477723C2 (ru) 2011-06-16 2013-03-20 Общество С Ограниченной Ответственностью "Фьюжн Фарма" Ингибиторы протеинкиназ (варианты), их применение для лечения онкологических заболеваний и фармацевтическая композиция на их основе
PT2810937T (pt) 2012-01-31 2017-03-03 Daiichi Sankyo Co Ltd Derivado de piridona
EP2879677B1 (en) 2012-07-28 2017-06-14 Calitor Sciences, LLC Substituted pyrazolone compounds and methods of use
US8975282B2 (en) 2012-07-28 2015-03-10 Sunshine Lake Pharma Co., Ltd. Substituted pyrazolone compounds and methods of use
US20140057920A1 (en) 2012-08-23 2014-02-27 Boehringer Ingelheim International Gmbh Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity
US20140057926A1 (en) * 2012-08-23 2014-02-27 Boehringer Ingelheim International Gmbh Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity
US9102624B2 (en) * 2012-08-23 2015-08-11 Boehringer Ingelheim International Gmbh Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity
TWI723572B (zh) 2014-07-07 2021-04-01 日商第一三共股份有限公司 具有四氫吡喃基甲基之吡啶酮衍生物及其用途
CN105153026B (zh) * 2015-08-21 2018-02-02 江西科技师范大学 含联芳基酰胺结构的索拉非尼衍生物及其制备方法和应用
WO2024067783A1 (zh) * 2022-09-28 2024-04-04 上海济煜医药科技有限公司 含磷类化合物及其制备方法和医药应用

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0430885A3 (en) 1989-12-01 1991-11-06 Ciba-Geigy Ag Anthelmintical compounds
US6143764A (en) 1995-11-07 2000-11-07 Kirin Beer Kabushiki Kaisha Quinoline and quinazoline derivatives inhibiting platelet-derived growth factor receptor autophosphorylation and pharmaceutical compositions containing the same
EP1087937A1 (en) 1998-06-17 2001-04-04 Du Pont Pharmaceuticals Company Cyclic hydroxamic acids as metalloproteinase inhibitors
US6355660B1 (en) 1999-07-20 2002-03-12 Dow Agrosciences Llc Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
WO2001005769A2 (en) 1999-07-20 2001-01-25 Dow Agrosciences Llc Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
WO2001021596A1 (en) 1999-09-21 2001-03-29 Astrazeneca Ab Quinazoline derivatives and their use as pharmaceuticals
WO2001070754A1 (en) * 2000-03-22 2001-09-27 Merck Frosst Canada & Co. Sulfur substituted aryldifluoromethylphosphonic acids as ptp-1b inhibitors
FR2812633A1 (fr) 2000-08-04 2002-02-08 Aventis Cropscience Sa Derives de phenyl(thio)urees et phenyl(thio)carbamates fongicides
SE0102384D0 (sv) 2001-07-03 2001-07-03 Pharmacia Ab New compounds
JP2005510564A (ja) 2001-11-28 2005-04-21 藤沢薬品工業株式会社 アポリポタンパク質ｂ阻害剤としての複素環式アミド化合物
SE0302487D0 (sv) 2003-09-18 2003-09-18 Astrazeneca Ab Novel compounds
JP2005263787A (ja) 2004-02-17 2005-09-29 Ishihara Sangyo Kaisha Ltd アミド系化合物又はその塩、並びにそれらを含有するサイトカイン産生抑制剤
US7459562B2 (en) * 2004-04-23 2008-12-02 Bristol-Myers Squibb Company Monocyclic heterocycles as kinase inhibitors
JP5097539B2 (ja) 2004-05-07 2012-12-12 アムジエン・インコーポレーテツド タンパク質キナーゼ調節剤および使用方法
US7432373B2 (en) 2004-06-28 2008-10-07 Bristol-Meyers Squibb Company Processes and intermediates useful for preparing fused heterocyclic kinase inhibitors
US7173031B2 (en) 2004-06-28 2007-02-06 Bristol-Myers Squibb Company Pyrrolotriazine kinase inhibitors
US7439246B2 (en) 2004-06-28 2008-10-21 Bristol-Myers Squibb Company Fused heterocyclic kinase inhibitors
JO2787B1 (en) 2005-04-27 2014-03-15 امجين إنك, Alternative amide derivatives and methods of use
WO2007033196A1 (en) 2005-09-14 2007-03-22 Bristol-Myers Squibb Company Met kinase inhibitors
WO2007035428A1 (en) 2005-09-15 2007-03-29 Bristol-Myers Squibb Company Met kinase inhibitors
US7348325B2 (en) 2005-11-30 2008-03-25 Bristol-Myers Squibb Company Pyrrolotriazine kinase inhibitors
ES2531396T3 (es) 2008-01-23 2015-03-13 Bristol Myers Squibb Co Proceso para preparar compuestos de piridinona

Also Published As

Publication number Publication date
HK1143157A1 (en) 2010-12-24
HRP20130040T1 (hr) 2013-02-28
BRPI0906444A8 (pt) 2020-02-27
CN101977906A (zh) 2011-02-16
US8124768B2 (en) 2012-02-28
NZ586630A (en) 2011-12-22
US20110034416A1 (en) 2011-02-10
DK2235002T3 (da) 2013-03-11
JP5314050B2 (ja) 2013-10-16
EA201001196A1 (ru) 2011-02-28
WO2009094417A1 (en) 2009-07-30
PT2235002E (pt) 2013-01-30
CN101977906B (zh) 2014-11-05
SI2235002T1 (sl) 2013-06-28
CY1114140T1 (el) 2016-07-27
BRPI0906444A2 (pt) 2015-07-14
CA2713111A1 (en) 2009-07-30
AU2009206440B2 (en) 2013-08-15
EP2235002A1 (en) 2010-10-06
KR20100103636A (ko) 2010-09-27
BRPI0906444B8 (pt) 2021-05-25
EP2235002B1 (en) 2012-11-21
IL207212A (en) 2015-01-29
KR101596527B1 (ko) 2016-02-22
EA017736B1 (ru) 2013-02-28
ZA201005248B (en) 2011-09-28
IL207212A0 (en) 2010-12-30
JP2011510087A (ja) 2011-03-31
AU2009206440A1 (en) 2009-07-30
CA2713111C (en) 2015-06-30
BRPI0906444B1 (pt) 2021-03-16
CO6230986A2 (es) 2010-12-20
US8258118B2 (en) 2012-09-04
US20120114643A1 (en) 2012-05-10
ES2398335T3 (es) 2013-03-15

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