HRP20131133T1 - Postupak za dobivanje 4-[(1,6-dihidro-6-okso-2-pirimidinil)amino benzonitrila - Google Patents

Postupak za dobivanje 4-[(1,6-dihidro-6-okso-2-pirimidinil)amino benzonitrila Download PDF

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Publication number
HRP20131133T1
HRP20131133T1 HRP20131133TT HRP20131133T HRP20131133T1 HR P20131133 T1 HRP20131133 T1 HR P20131133T1 HR P20131133T T HRP20131133T T HR P20131133TT HR P20131133 T HRP20131133 T HR P20131133T HR P20131133 T1 HRP20131133 T1 HR P20131133T1
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HR
Croatia
Prior art keywords
formula
acid
compound
process according
image
Prior art date
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HRP20131133TT
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English (en)
Croatian (hr)
Inventor
Didier Philippe Robert Schils
Alfred Elisabeth Stappers
Original Assignee
Janssen R&D Ireland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35822492&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20131133(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen R&D Ireland filed Critical Janssen R&D Ireland
Publication of HRP20131133T1 publication Critical patent/HRP20131133T1/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HRP20131133TT 2005-05-26 2006-05-24 Postupak za dobivanje 4-[(1,6-dihidro-6-okso-2-pirimidinil)amino benzonitrila HRP20131133T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05104531 2005-05-26
US68599305P 2005-05-31 2005-05-31
PCT/EP2006/062606 WO2006125809A1 (en) 2005-05-26 2006-05-24 Process for preparing 4-[(1,6-dihydro-6-oxo-2-pyrimidinyl)amino benzonitrile

Publications (1)

Publication Number Publication Date
HRP20131133T1 true HRP20131133T1 (hr) 2014-01-03

Family

ID=35822492

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20131133TT HRP20131133T1 (hr) 2005-05-26 2006-05-24 Postupak za dobivanje 4-[(1,6-dihidro-6-okso-2-pirimidinil)amino benzonitrila

Country Status (19)

Country Link
US (2) US8101752B2 (en17)
EP (1) EP1888537B1 (en17)
JP (2) JP5148483B2 (en17)
CN (1) CN101248051B (en17)
AU (1) AU2006251163C1 (en17)
BR (1) BRPI0611038B8 (en17)
CA (1) CA2609716C (en17)
DK (1) DK1888537T3 (en17)
ES (1) ES2437202T3 (en17)
HR (1) HRP20131133T1 (en17)
IN (1) IN2014DN04588A (en17)
ME (1) ME01612B (en17)
MX (1) MX2007014881A (en17)
PL (1) PL1888537T3 (en17)
PT (1) PT1888537E (en17)
RS (1) RS53062B (en17)
RU (1) RU2458056C2 (en17)
SI (1) SI1888537T1 (en17)
WO (1) WO2006125809A1 (en17)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006125809A1 (en) * 2005-05-26 2006-11-30 Tibotec Pharmaceuticals Ltd Process for preparing 4-[(1,6-dihydro-6-oxo-2-pyrimidinyl)amino benzonitrile
WO2012125993A1 (en) 2011-03-17 2012-09-20 Teva Pharmaceutical Industries Ltd. Solid state forms of rilpivirine base, and rilipivirine salts
WO2013135684A1 (en) 2012-03-13 2013-09-19 Octapharma Ag Improved process for production of fibrinogen and fibrinogen produced thereby
CN103058936B (zh) * 2013-01-23 2016-01-06 宁波九胜创新医药科技有限公司 4-[(4-氯-2-嘧啶基)氨基]苯腈的制备方法
CN103193719B (zh) * 2013-04-08 2015-07-22 宁波九胜创新医药科技有限公司 一种4-[(4-羟基-2-嘧啶基)氨基]苯腈的制备方法
CN114933567B (zh) * 2022-04-29 2023-07-11 武汉工程大学 一种2-甲硫基-4-嘧啶酮的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63502B1 (en) 1989-04-21 1995-05-03 Zeneca Ltd Aminopyrimidine derivatives useful for treating cardiovascular disorders
RU2037483C1 (ru) * 1989-07-20 1995-06-19 Мерк Патент Гмбх Способ получения замещенных ароматических нитрилов
DE3923979A1 (de) 1989-07-20 1991-01-24 Merck Patent Gmbh Verfahren zur herstellung von aromatischen nitrilen
WO1999050250A1 (en) * 1998-03-27 1999-10-07 Janssen Pharmaceutica N.V. Hiv inhibiting pyrimidine derivatives
EE05086B1 (et) * 1998-11-10 2008-10-15 Janssen Pharmaceutica N.V. Primidiini derivaadid, nende valmistamismeetod ja kasutamine, farmatseutiline kompositsioon ja selle valmistamismeetod, kombinatsioon ning saadus
BRPI0014271B1 (pt) * 1999-09-24 2021-06-22 Janssen Pharmaceutica N.V. Partícula consistindo em uma dispersão de sólidos, uso da dita partícula, dispersão de sólidos, forma de dosagem farmacêutica, bem como processos de preparação de dita partícula, dispersão e forma de dosagem
EP1282607B1 (en) * 2000-05-08 2015-11-11 Janssen Pharmaceutica NV Prodrugs of hiv replication inhibiting pyrimidines
JO3429B1 (ar) * 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv مشتقات برميدينات مثبطة فيروس الايدز
MXPA04004178A (es) * 2001-11-01 2004-09-06 Janssen Pharmaceutica Nv Heteroarilaminas como inhibidores de glucogeno cintasa cinasa 3beta.
AU2003266413B2 (en) * 2002-08-09 2009-04-02 Janssen Pharmaceutica N.V. Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
AU2004286933B2 (en) * 2003-09-30 2010-11-18 Janssen Pharmaceutica N.V. Benzoimidazole compounds
WO2006125809A1 (en) * 2005-05-26 2006-11-30 Tibotec Pharmaceuticals Ltd Process for preparing 4-[(1,6-dihydro-6-oxo-2-pyrimidinyl)amino benzonitrile

Also Published As

Publication number Publication date
CN101248051B (zh) 2013-07-17
US8101752B2 (en) 2012-01-24
EP1888537B1 (en) 2013-09-11
DK1888537T3 (da) 2013-12-09
HK1123551A1 (en) 2009-06-19
WO2006125809A1 (en) 2006-11-30
AU2006251163B2 (en) 2012-03-08
RS53062B (en) 2014-04-30
JP2008545680A (ja) 2008-12-18
RU2007148968A (ru) 2009-07-10
US20120083606A1 (en) 2012-04-05
US20080171878A1 (en) 2008-07-17
US8618291B2 (en) 2013-12-31
ES2437202T3 (es) 2014-01-09
BRPI0611038B8 (pt) 2022-10-25
RU2458056C2 (ru) 2012-08-10
BRPI0611038B1 (pt) 2022-02-08
ME01612B (me) 2014-09-20
JP2013040194A (ja) 2013-02-28
CN101248051A (zh) 2008-08-20
AU2006251163A1 (en) 2006-11-30
EP1888537A1 (en) 2008-02-20
IN2014DN04588A (en17) 2015-07-10
PT1888537E (pt) 2013-11-26
JP5148483B2 (ja) 2013-02-20
CA2609716C (en) 2014-10-14
SI1888537T1 (sl) 2014-01-31
BRPI0611038A2 (pt) 2010-08-10
CA2609716A1 (en) 2006-11-30
MX2007014881A (es) 2008-02-15
JP5580385B2 (ja) 2014-08-27
AU2006251163C1 (en) 2012-07-12
PL1888537T3 (pl) 2014-02-28

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