HRP20100086T1 - (2R,4aR,10bR)-6-(2,6-DIMETOKSIPIRIDIN-3-IL)-9-ETOKSI-8-METOKSI-1,2,3,4,4a,10b-HEKSAHIDROFENANTRIDIN-2-ol, HCI SOL - Google Patents

(2R,4aR,10bR)-6-(2,6-DIMETOKSIPIRIDIN-3-IL)-9-ETOKSI-8-METOKSI-1,2,3,4,4a,10b-HEKSAHIDROFENANTRIDIN-2-ol, HCI SOL Download PDF

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Publication number
HRP20100086T1
HRP20100086T1 HR20100086T HRP20100086T HRP20100086T1 HR P20100086 T1 HRP20100086 T1 HR P20100086T1 HR 20100086 T HR20100086 T HR 20100086T HR P20100086 T HRP20100086 T HR P20100086T HR P20100086 T1 HRP20100086 T1 HR P20100086T1
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Prior art keywords
salt according
hexahydrophenanthridin
dimethoxypyridin
ethoxy
methoxy
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HR20100086T
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English (en)
Inventor
Kautz Ulrich
Webel Matthias
Scheufler Christian
Hummel Rolf-Peter
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Nycomed Gmbh
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Publication of HRP20100086T1 publication Critical patent/HRP20100086T1/hr

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Abstract

Spoj, naznačen time, da je (2R,4aR,10bR)-6-(2,6-dimetoksipiridin-3-il)-9-etoksi-8-metoksi-1,2,3,4,4a,10b-heksahidrofenantridin-2-ol hidroklorid. Patent sadrži još 8 patentnih zahtjeva.

Claims (9)

1. Spoj, naznačen time, da je (2R,4aR,10bR)-6-(2,6-dimetoksipiridin-3-il)-9-etoksi-8-metoksi-1,2,3,4,4a,10b-heksahidrofenantridin-2-ol hidroklorid.
2. Spoj, naznačen time, da je solvatni oblik soli u skladu sa zahtjevom 1.
3. Spoj, naznačen time, da je hidratni oblik soli u skladu sa zahtjevom 1.
4. Sol u skladu s bilo kojim zahtjevom 1 do 3, naznačena time, da je u kristaliničnom obliku.
5. Sol u skladu s bilo kojim zahtjevom 1 do 4, naznačena time, da je u krutom dozirnom obliku.
6. Sol u skladu s bilo kojim zahtjevom 1 do 4, naznačena time, da je za uporabu u liječenju bolesti.
7. Farmaceutski pripravak, naznačen time, da sadrži sol u skladu s bilo kojim zahtjevom 1 do 4 zajedno s farmaceutskim pomoćnim tvarima i/ili punilima.
8. Uporaba soli u skladu s bilo kojim zahtjevom 1 do 4, naznačena time, da se koristi za pripremu farmaceutskih pripravaka za liječenje PDE4 posredovanih poremećaja.
9. Uporaba soli u skladu s bilo kojim zahtjevom 1 do 4, naznačena time, da se koristi za pripremu farmaceutskih pripravaka za liječenje diabetes mellitus-a.
HR20100086T 2005-03-02 2010-02-18 (2R,4aR,10bR)-6-(2,6-DIMETOKSIPIRIDIN-3-IL)-9-ETOKSI-8-METOKSI-1,2,3,4,4a,10b-HEKSAHIDROFENANTRIDIN-2-ol, HCI SOL HRP20100086T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05101619 2005-03-02
EP05108442 2005-09-14
PCT/EP2006/060377 WO2006092422A1 (en) 2005-03-02 2006-03-01 Novel salts of 6-heterocyclyl substituted hexahydrophenanthridine derivatives

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HRP20100086T1 true HRP20100086T1 (hr) 2010-04-30

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HR20100086T HRP20100086T1 (hr) 2005-03-02 2010-02-18 (2R,4aR,10bR)-6-(2,6-DIMETOKSIPIRIDIN-3-IL)-9-ETOKSI-8-METOKSI-1,2,3,4,4a,10b-HEKSAHIDROFENANTRIDIN-2-ol, HCI SOL

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EP (3) EP1856093B1 (hr)
JP (2) JP5478828B2 (hr)
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ES (2) ES2337083T3 (hr)
HR (1) HRP20100086T1 (hr)
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Families Citing this family (11)

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Publication number Priority date Publication date Assignee Title
DE60311662T2 (de) 2002-08-29 2007-10-25 Altana Pharma Ag 3-hydroxy-6-phenylphenanthridine als pde-4 inhibitoren
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